Dual Threshold Optimization compares two ranked lists of features (e.g. genes) to determine the rank threshold for each list that minimizes the hypergeometric p-value of the overlap of features. It then calculates a permutation based empirical p-value and an FDR
bioinformatics transcription-factors transcription-factor-binding transcriptional-regulatory-network regulatory-network geneset-enrichment-analysis transcription-factor-perturbation regulatory-genomics
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Updated
Dec 5, 2024 - Rust