Background
Rabies virus (RABV) causes around 59,000 deaths each year and exceeds $8.6 billion in annual costs. While rabies can affect all mammals, up to 99% of human cases result from bites by infected domestic dogs, and vaccination of dogs is a vital component of control strategies. Because canine infections usually originate in wildlife, genomic surveillance is crucial for detecting and monitoring potential wildlife reservoirs.
Footnote:
RABV-GLUE is a sequence-oriented resource developed to support effective and coordinated genomic surveillance of RABV. It can be installed as a local resource and is also accessible via an online interface. It comprises an interactive database of curated, phylogenetically structured RABV sequence data, automatically updated via periodic downloads from NCBI GenBank. The online version provides access to a subset of its features and functionalities, including a genotyping function, support for analysis and visualisation of sequences, and pre-built, downloadable sequence alignments.