Patch nfosi 266

NF.csv

@@ -296,6 +296,7 @@ CD138+,"","","",FALSE,"",cellType,,"","",CD138_positive,Class,Biosample,Cell,Cel
 CNON,Cultured Neuronal cells derived from Olfactory Neuroepithelium,"","",FALSE,https://www.synapse.org/#!Synapse:syn4590897,cellType,,"","",CNON,Class,Biosample,Cell,Cell,"","",""
 teratoma,"A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C3403,cellType,,"","",Teratoma,Class,Biosample,Cell,Cell,"","",""
 cultured Muller glia,"Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. [ http://www.ncbi.nlm.nih.gov/pubmed/21911394 GOC : NV ]","","",FALSE,http://purl.obolibrary.org/obo/CL_0000636,cellType,,"","",Müller cell,Class,Biosample,Cell,Cell,"","",""
+DRG/nerve root neurosphere cell,"Dorsal root ganglia/nerve root neurosphere cells (DNSCs) are cultured from embryonic DRGs/nerve roots and have been used in in vitro sphere assays to study the origin of para-spinal neurofibromas. See reference PMC4254535","","",FALSE,,cellType,,"","",DNSC,Class,Biosample,Cell,Cell,"","",""
 Neurofibromatosis type 1,"(NF1) - A disease characterized by patches of skin pigmentation (cafe-au-lait spots), Lisch nodules of the iris, tumors in the peripheral nervous system and fibromatous skin tumors. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors.","","",FALSE,"",diagnosis,,"","",Neurofibromatosis_Type_1,Class,Biosample,Diagnosis,"","","",""
 Neurofibromatosis type 2,"(NF2) - Genetic disorder characterized by bilateral vestibular schwannomas (formerly called acoustic neuromas), schwannomas of other cranial and peripheral nerves, meningiomas, and ependymomas. It is inherited in an autosomal dominant fashion with full penetrance.","","",FALSE,https://www.ebi.ac.uk/ols/ontologies/cco/terms?iri=http%3A%2F%2Fidentifiers.org%2Fomim%2F101000,diagnosis,,"","",Neurofibromatosis_Type_2,Class,Biosample,Diagnosis,"","","",""
 Schwannomatosis,A rare genetic disorder characterized by the presence of multiple schwannomas.,"","",FALSE,https://www.ebi.ac.uk/ols/ontologies/ncit/terms?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FNCIT_C6557,diagnosis,,"","",Schwannomatosis,Class,Biosample,Diagnosis,"","","",""
@@ -511,7 +512,7 @@ individualIdSource,Database or repository to which individual ID maps,,,FALSE,,e
 tissue,A tissue is a mereologically maximal collection of cells that together perform physiological function.,"nerve tissue,optic nerve,serum,plasma,splenocyte,blood,primary tumor,embryonic tissue,meninges,bone marrow,Buccal Mucosa,Dorsal Root Ganglion,unspecified,whole brain,Buffy Coat,cerebral cortex,sciatic nerve,connective tissue,tumor-adjacent normal, PDX tissue, CDX tissue, metastatic/recurrent tumor, recurrent tumor, metastatic tumor, organoid, spheroid, microtissue, retina",,FALSE,,experimentalData,,,,tissueType,Property,Biosample,annotationProperty,,Tissue,,
 isCellLine,Whether or not sample source is a cell line (Yes; No),"Yes, No",,FALSE,,experimentalData,,,,isCellLine,DataProperty,Biosample,annotationProperty,,,,
 isPrimaryCell,Whether or not cellType is primary (Yes; No),"Yes, No",,FALSE,,experimentalData,,,,isPrimaryCell,DataProperty,Biosample,annotationProperty,,,,
-cellType,A cell type is a distinct morphological or functional form of cell.,"Schwann cell precursor, B-lymphocytes, Embryonic stem cells, iPSC, iPSC-derived telencephalic organoids, GABAergic neurons, monocytes, microglia, macrophages, astrocytes, SH-SY5Y, GLUtamatergic neurons, NeuN+, NeuN-, epithelial, epithelial-like, fibroblast, round, lymphoblast, CD8+ T-Cells, arachnoid, meningioma, schwannoma, oligodendrocyte, schwann, iPSC-derived neuron, iPSC-derived glia, iPSC-derived astrocytes, monocyte-derived microglia, iPSC-derived neuronal progenitor cell, CD138+, CNON, teratoma, cultured Muller glia",,FALSE,,experimentalData,,,list,cellType,DataProperty,Biosample,annotationProperty,,Cell,,
+cellType,A cell type is a distinct morphological or functional form of cell.,"Schwann cell precursor, B-lymphocytes, Embryonic stem cells, iPSC, iPSC-derived telencephalic organoids, GABAergic neurons, monocytes, microglia, macrophages, astrocytes, SH-SY5Y, GLUtamatergic neurons, NeuN+, NeuN-, epithelial, epithelial-like, fibroblast, round, lymphoblast, CD8+ T-Cells, arachnoid, meningioma, schwannoma, oligodendrocyte, schwann, iPSC-derived neuron, iPSC-derived glia, iPSC-derived astrocytes, monocyte-derived microglia, iPSC-derived neuronal progenitor cell, CD138+, CNON, teratoma, cultured Muller glia, DRG/nerve root neurosphere cell",,FALSE,,experimentalData,,,list,cellType,DataProperty,Biosample,annotationProperty,,Cell,,
 isMultiIndividual,Whether or not a file has data for multiple individuals (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,isMultiIndividual,DataProperty,Biosample,annotationProperty,,,,
 isMultiSpecimen,Whether or not a file has data for multiple specimens (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,isMultiSpecimen,DataProperty,Biosample,annotationProperty,,,,
 sex,"Phenotypic expression of chromosomal makeup that defines a study subject as male, female, or other.","Male, Female, Unknown",,FALSE,http://purl.obolibrary.org/obo/NCIT_C28421,experimentalData,,,,sex,Property,Biosample,annotationProperty,,Sex,,

NF.jsonld

@@ -7701,6 +7701,23 @@
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
+        {
+            "@id": "bts:DRG/nerverootneurospherecell",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Dorsal root ganglia/nerve root neurosphere cells (DNSCs) are cultured from embryonic DRGs/nerve roots and have been used in in vitro sphere assays to study the origin of para-spinal neurofibromas. See reference PMC4254535",
+            "rdfs:label": "DRG/nerverootneurospherecell",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "DRG/nerve root neurosphere cell",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
         {
             "@id": "bts:Neurofibromatosistype1",
             "@type": "rdfs:Class",
@@ -11913,6 +11930,9 @@
                 },
                 {
                     "@id": "bts:CulturedMullerglia"
+                },
+                {
+                    "@id": "bts:DRG/nerverootneurospherecell"
                 }
             ],
             "sms:displayName": "cellType",

modules/Biosample/Cell.csv

@@ -33,3 +33,4 @@ CD138+,"","","",FALSE,"",cellType,,"","",CD138_positive,Class,Biosample,Cell,Cel
 CNON,Cultured Neuronal cells derived from Olfactory Neuroepithelium,"","",FALSE,https://www.synapse.org/#!Synapse:syn4590897,cellType,,"","",CNON,Class,Biosample,Cell,Cell,"","",""
 teratoma,"A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C3403,cellType,,"","",Teratoma,Class,Biosample,Cell,Cell,"","",""
 cultured Muller glia,"Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. [ http://www.ncbi.nlm.nih.gov/pubmed/21911394 GOC : NV ]","","",FALSE,http://purl.obolibrary.org/obo/CL_0000636,cellType,,"","",Müller cell,Class,Biosample,Cell,Cell,"","",""
+DRG/nerve root neurosphere cell,"Dorsal root ganglia/nerve root neurosphere cells (DNSCs) are cultured from embryonic DRGs/nerve roots and have been used in in vitro sphere assays to study the origin of para-spinal neurofibromas. See reference PMC4254535","","",FALSE,,cellType,,"","",DNSC,Class,Biosample,Cell,Cell,"","",""

modules/Biosample/annotationProperty.csv

@@ -8,7 +8,7 @@ individualIdSource,Database or repository to which individual ID maps,,,FALSE,,e
 tissue,A tissue is a mereologically maximal collection of cells that together perform physiological function.,"nerve tissue,optic nerve,serum,plasma,splenocyte,blood,primary tumor,embryonic tissue,meninges,bone marrow,Buccal Mucosa,Dorsal Root Ganglion,unspecified,whole brain,Buffy Coat,cerebral cortex,sciatic nerve,connective tissue,tumor-adjacent normal, PDX tissue, CDX tissue, metastatic/recurrent tumor, recurrent tumor, metastatic tumor, organoid, spheroid, microtissue, retina",,FALSE,,experimentalData,,,,tissueType,Property,Biosample,annotationProperty,,Tissue,,
 isCellLine,Whether or not sample source is a cell line (Yes; No),"Yes, No",,FALSE,,experimentalData,,,,isCellLine,DataProperty,Biosample,annotationProperty,,,,
 isPrimaryCell,Whether or not cellType is primary (Yes; No),"Yes, No",,FALSE,,experimentalData,,,,isPrimaryCell,DataProperty,Biosample,annotationProperty,,,,
-cellType,A cell type is a distinct morphological or functional form of cell.,"Schwann cell precursor, B-lymphocytes, Embryonic stem cells, iPSC, iPSC-derived telencephalic organoids, GABAergic neurons, monocytes, microglia, macrophages, astrocytes, SH-SY5Y, GLUtamatergic neurons, NeuN+, NeuN-, epithelial, epithelial-like, fibroblast, round, lymphoblast, CD8+ T-Cells, arachnoid, meningioma, schwannoma, oligodendrocyte, schwann, iPSC-derived neuron, iPSC-derived glia, iPSC-derived astrocytes, monocyte-derived microglia, iPSC-derived neuronal progenitor cell, CD138+, CNON, teratoma, cultured Muller glia",,FALSE,,experimentalData,,,list,cellType,DataProperty,Biosample,annotationProperty,,Cell,,
+cellType,A cell type is a distinct morphological or functional form of cell.,"Schwann cell precursor, B-lymphocytes, Embryonic stem cells, iPSC, iPSC-derived telencephalic organoids, GABAergic neurons, monocytes, microglia, macrophages, astrocytes, SH-SY5Y, GLUtamatergic neurons, NeuN+, NeuN-, epithelial, epithelial-like, fibroblast, round, lymphoblast, CD8+ T-Cells, arachnoid, meningioma, schwannoma, oligodendrocyte, schwann, iPSC-derived neuron, iPSC-derived glia, iPSC-derived astrocytes, monocyte-derived microglia, iPSC-derived neuronal progenitor cell, CD138+, CNON, teratoma, cultured Muller glia, DRG/nerve root neurosphere cell",,FALSE,,experimentalData,,,list,cellType,DataProperty,Biosample,annotationProperty,,Cell,,
 isMultiIndividual,Whether or not a file has data for multiple individuals (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,isMultiIndividual,DataProperty,Biosample,annotationProperty,,,,
 isMultiSpecimen,Whether or not a file has data for multiple specimens (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,isMultiSpecimen,DataProperty,Biosample,annotationProperty,,,,
 sex,"Phenotypic expression of chromosomal makeup that defines a study subject as male, female, or other.","Male, Female, Unknown",,FALSE,http://purl.obolibrary.org/obo/NCIT_C28421,experimentalData,,,,sex,Property,Biosample,annotationProperty,,Sex,,