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mobiusklein/README.md

I'm a bioinformatician who works with mass spectrometry data. My PhD was dedicated to developing computational methods for glycomics and glycoproteomics, finding integrated-omics strategies to dig deeper into complex biological samples. My professional work has involved using that knowledge to analyze immunopeptidomics data to help develop better vaccines for personalized cancer immunotherapy and multi-strain infectious disease protection, using a combination deep learning, population sampling, and sequence conservation models.

🔔 I am actively seeking a new position in bioinformatics or a related domain.

📧 Email me if you want to discuss MS data processing techniques, glycoinformatics, or antigenomics

🔬 Active Projects

I am actively working on migrating much of the I/O and signal processing code I have written in Python/C to Rust

  • mzdata - The I/O and spectrum data layer, including some fancy iterators and convenience functions for reading and writing mass spectrometry data files.
  • mzpeaks - Types and traits for generic representation of peaks and features for mass spectrometry, including searchable collections and spatial data structures.
  • mzsignal - Algorithms for low-level signal processing of mass spectra and temporal traces like chromatograms or mobilograms, including peak picking, feature extraction, signal averaging, smoothing and denoising.
  • mzdeisotope - Algorithms for charge state deconvolution and deisotoping of mass spectra and feature maps.
  • mass-fragment-index - Data structures for large-scale searching of precursor-product collections suitable for fragment indices, spectral libraries, or similar data. Includes fast-to-search on-disk serialization.

I am also experimenting with adapting some ML/DL methods from regular proteomics to glycoproteomics.

Popular repositories Loading

  1. cython_pyinstaller_example cython_pyinstaller_example Public

    A simple example repository describing the process of building a PyInstaller executable for a Cython-compiled program

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  2. ms_deisotope ms_deisotope Public

    A library for deisotoping and charge state deconvolution of complex mass spectra

    Python 34 13

  3. glypy glypy Public

    Glycan Analysis and Glycoinformatics Library for Python

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  4. mzdata mzdata Public

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  5. ms_peak_picker ms_peak_picker Public

    A small library to provide peak picking for software processing mass spectrometry data

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  6. psims psims Public

    A declarative API for writing XML documents for HUPO PSI-MS mzML and mzIdentML

    Python 20 10