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Licensable software to help model and reconstruct neurons and their functions. Work done based off of data and reconstructions from Harvard, Yale, and other academic institutions as well as open source data.

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Sculpt 🧠

A Multi-Omics Deep Learning Framework for Decoding Cerebral Cortex Localization

Overview

Sculpt is an open source project focused on advanced multi-omics modeling to elucidate neuronal architecture. This project combines cutting-edge techniques in 3D interneuron/neuron image modeling, leveraging work from NIH and the University of Maryland.

Key Features

  • Instance segmentation for detailed neuron analysis
  • Frame-by-frame image modeling
  • 3D neuron prediction from multiomics data
  • SEM visualization integration

Usage

Feel free to use any of the code in this repository. However, we kindly request that you cite this GitHub Project when doing so.

Methodology

The project utilizes instance segmentation along with frame-by-frame image modeling to create predicted 3D neurons from multiomics data and SEM visualization.

Collaboration

This project was developed in part through collaboration with Google Research and Harvard University, focusing on 3D interneuron/neuron image modeling.

Contributing

This is an open source project, and all code and push updates will be posted on this project repository. Contributions are welcome!

Future Updates

Additional contributors and references will be cited in future updates to this README.

Contact

Email: talluri.ganeshsai@gmail.com or ashwinrokss@gmail.com


Note: This README is a living document and will be updated as the project evolves.

About

Licensable software to help model and reconstruct neurons and their functions. Work done based off of data and reconstructions from Harvard, Yale, and other academic institutions as well as open source data.

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