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Hi-C integrative catalog

This repository contains codes and processed files for the manuscript entitled "A comprehensive catalog of 3D genome organization in diverse human genomes facilitates understanding of the impact of structural variation on chromatin structure". Specifically, it includes the codes corresponding to the analyses of the main results listed below:

  1. TAD boundary calling by Insulation Score
  2. Comprehensive TAD catalog integration
  3. Quantification of SVs’ impact on 3D chromatin structure, gene expression, and splicing levels

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