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Updated schistosomiasis model #1587

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Updated schistosomiasis model #1587

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tdm32
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@tdm32 tdm32 commented Feb 12, 2025

This updated version of the schistosomiasis code has the following features:

  • all input data are updated (MDA coverage, infection burden)
  • many key parameters are updated
  • two diagnostic tests for different species, both have varying sensitivity and specificity based on individual worm burden
  • individuals now have a susceptibility property, which determines whether they are susceptible to schisto infection, this is calibrated to match infection prevalence
  • effects of WASH properties on schisto risk (proportion susceptible) now incorporated
  • updated logging includes person-years of infection by species and infection intensity (and district / age-group)
  • new test added
  • correct consumables dosage (by individual weight by age if treatment, by average weight of age-group if through MDA)
  • functionality to manipulate future MDA schedules as parameter inputs to module
  • background risk of infection dependent on deviation from baseline prevalence, when disease prevalence increases, background risk also increases reflecting higher likelihood of new infections (and reduces stochastic fadeout in small populations)
  • symptoms now linked with moderate/high worm burden and assigned probabilistically
  • links to bladder cancer and HIV included where relevant
  • can assign all individuals in simulation to one district through module keyword

tdm32 added 30 commits February 27, 2024 14:04
…r). Update ResourceFile_Oesophageal_Cancer.xlsx
…lsx with rr_hiv, leave value=1.0 if no effect of hiv
…eFile_TB.xlsx

replace linearmodels dict which was accidentally removed in depression.py
…ns between schisto->hiv, schisto->bladder cancer
tdm32 added 30 commits January 3, 2025 16:30
increased odd_ratio of HSB for some symptoms
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