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update readme
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xiao-chen-xc committed Jan 26, 2023
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Expand Up @@ -6,6 +6,8 @@ Chen X, Harting J, Farrow E, et al. Comprehensive SMN1 and SMN2 profiling for sp

For whole-genome sequencing (WGS) data, we recommend >20X, ideally 30X, genome coverage. Low coverage or short read length could result in less accurate phasing, especially when haplotypes are highly similar to each other in Exons 1-6. For hybrid capture-based enrichment data, a higher read depth (>50X) is recommended as the read length is generally shorter than WGS.

Currently Paraphase only works on GRCh38. Support for GRCh37 will be adde in the future.

## Contact

If you need assistance or have suggestions, please don't hesitate to reach out by email or open a GitHub issue.
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