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DESCRIPTION
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Package: HorGeneVis
Type: Package
Title: Horizontal Gene Transfer Visualization
Version: 1.0.0
Authors@R: c(
person("Jana", "Schwarzerova", email = "Jana.Schwarzerova@vut.cz", role = c("aut", "cre"),
comment = c(ORCID = "0000-0003-2918-9313")),
person("Laxmipriya", "Rajasekaran", role = "aut", comment = c(ORCID = "0009-0000-6401-7731")),
person("Katerina", "Jureckova", role = "aut", comment = c(ORCID = "0000-0001-5143-9521")),
person("Julie", "Nejezchlebova", role = "aut", comment = c(ORCID = "0009-0008-2290-6467")),
person("Margaret", "Varga", role = "aut", comment = c(ORCID = "0000-0002-9086-1626")),
person("Valentine", "Provaznik", role = "aut", comment = c(ORCID = "0000-0002-3422-7938")),
person("Wolfram", "Weckwerth", role = "aut", comment = c(ORCID = "0000-0002-9719-6358")),
person("Darina", "Cejkova", role = c("aut", "fnd"), comment = c(ORCID = "0000-0002-6989-6330"))
)
Description:
This package involves the analysis and visualization of horizontal gene transfer (HGT) between individual taxonomic
categories using genomic data. The tool combines the integration of a heat-map matrix with phylogenetic analysis
visualization techniques to enhance the accuracy and efficiency of HGT event detection. We applied it to a diverse
set of bacterial genomes from chicken and pig gut and expanded the results with established methods for HGT
detection. The findings demonstrate the capability of our visualization techniques to pinpoint HGT events, offering
a valuable tool for researchers to explore the intricate dynamics of bacterial genome evolution.
License: GPL-3
Encoding: UTF-8
Imports:
ape,
circlize,
RColorBrewer
References:
- Schwarzerova, J., Rajasekaran, L., Jureckova, K., Nejezchlebova, J., Varga, M., Provaznik, V., et al. (2024).
“Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria,” in Bioinformatics and
Biomedical Engineering, 1–11.
- Schwarzerova, J., Zeman, M., Babak, V., Jureckova, K., Nykrynova, M., Varga, M., et al. (2024).
Detecting horizontal gene transfer among microbiota: an innovative pipeline for identifying co-shared genes within
the mobilome through advanced comparative analysis. Microbiol. Spectr. 12, e01964-23. doi:10.1128/spectrum.01964-23.
URL: https://github.com/JanaSchwarzerova/HorGeneVis
BugReports: https://github.com/JanaSchwarzerova/HorGeneVis/issues
RoxygenNote: 7.3.2
Roxygen: list(markdown = TRUE)