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adjust logic around goi subsetting and re-run
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cbethell committed May 13, 2021
1 parent 3ad02de commit d71f76b
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4 changes: 2 additions & 2 deletions analyses/oncoprint-landscape/02-plot-oncoprint.R
Original file line number Diff line number Diff line change
Expand Up @@ -258,15 +258,15 @@ if (!is.null(opt$goi_list)){
goi_list <- readr::read_tsv(opt$goi_list) %>%
as.matrix()

maf_object <- subsetMaf(
filtered_maf_object <- subsetMaf(
maf = maf_object,
tsb = metadata$Tumor_Sample_Barcode,
genes = goi_list,
mafObj = TRUE
)

# Get top mutated genes per this subset object
gene_sum <- mafSummary(maf_object)$gene.summary
gene_sum <- mafSummary(filtered_maf_object)$gene.summary

# Sort to get top altered genes rather than mutated only genes
goi_list <- gene_sum %>%
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