diff --git a/.changeset/dirty-zoos-provide.md b/.changeset/dirty-zoos-provide.md
new file mode 100644
index 000000000000..5c306e79a6f6
--- /dev/null
+++ b/.changeset/dirty-zoos-provide.md
@@ -0,0 +1,5 @@
+---
+'astro': patch
+---
+
+Fix: avoid calling `astro:server:setup` integration hook in production
diff --git a/packages/astro/src/core/create-vite.ts b/packages/astro/src/core/create-vite.ts
index 1879daac83b3..54a8ce016fd9 100644
--- a/packages/astro/src/core/create-vite.ts
+++ b/packages/astro/src/core/create-vite.ts
@@ -19,7 +19,6 @@ import envVitePlugin from '../vite-plugin-env/index.js';
 import astroHeadPlugin from '../vite-plugin-head/index.js';
 import htmlVitePlugin from '../vite-plugin-html/index.js';
 import { astroInjectEnvTsPlugin } from '../vite-plugin-inject-env-ts/index.js';
-import astroIntegrationsContainerPlugin from '../vite-plugin-integrations-container/index.js';
 import jsxVitePlugin from '../vite-plugin-jsx/index.js';
 import astroLoadFallbackPlugin from '../vite-plugin-load-fallback/index.js';
 import markdownVitePlugin from '../vite-plugin-markdown/index.js';
@@ -119,7 +118,6 @@ export async function createVite(
 			htmlVitePlugin(),
 			jsxVitePlugin({ settings, logging }),
 			astroPostprocessVitePlugin({ settings }),
-			astroIntegrationsContainerPlugin({ settings, logging }),
 			astroScriptsPageSSRPlugin({ settings }),
 			astroHeadPlugin({ settings }),
 			astroScannerPlugin({ settings }),
diff --git a/packages/astro/src/vite-plugin-integrations-container/index.ts b/packages/astro/src/vite-plugin-integrations-container/index.ts
deleted file mode 100644
index 0169a6f71560..000000000000
--- a/packages/astro/src/vite-plugin-integrations-container/index.ts
+++ /dev/null
@@ -1,20 +0,0 @@
-import type { Plugin as VitePlugin } from 'vite';
-import type { AstroSettings } from '../@types/astro.js';
-import type { LogOptions } from '../core/logger/core.js';
-import { runHookServerSetup } from '../integrations/index.js';
-
-/** Connect Astro integrations into Vite, as needed. */
-export default function astroIntegrationsContainerPlugin({
-	settings,
-	logging,
-}: {
-	settings: AstroSettings;
-	logging: LogOptions;
-}): VitePlugin {
-	return {
-		name: 'astro:integration-container',
-		configureServer(server) {
-			runHookServerSetup({ config: settings.config, server, logging });
-		},
-	};
-}