diff --git a/go/vt/vterrors/constants.go b/go/vt/vterrors/constants.go
index 2008e1ccbc1..50df5445354 100644
--- a/go/vt/vterrors/constants.go
+++ b/go/vt/vterrors/constants.go
@@ -41,3 +41,9 @@ const (
 	// PrimaryVindexNotSet is the error message to be used when there is no primary vindex found on a table
 	PrimaryVindexNotSet = "table '%s' does not have a primary vindex"
 )
+
+// TxKillerRollback purpose when acquire lock on connection for rolling back transaction.
+const TxKillerRollback = "in use: for tx killer rollback"
+
+// TxClosed regex for connection closed
+var TxClosed = regexp.MustCompile("transaction ([a-z0-9:]+) (?:ended|not found|in use: for tx killer rollback)")
diff --git a/go/vt/vtgate/scatter_conn.go b/go/vt/vtgate/scatter_conn.go
index 3d890c77ffb..ee0f6912630 100644
--- a/go/vt/vtgate/scatter_conn.go
+++ b/go/vt/vtgate/scatter_conn.go
@@ -20,7 +20,6 @@ import (
 	"context"
 	"flag"
 	"io"
-	"regexp"
 	"sync"
 	"time"
 
@@ -709,8 +708,6 @@ func (stc *ScatterConn) ExecuteLock(
 	return qr, err
 }
 
-var txClosed = regexp.MustCompile("transaction ([a-z0-9:]+) (?:ended|not found)")
-
 func wasConnectionClosed(err error) bool {
 	sqlErr := mysql.NewSQLErrorFromError(err).(*mysql.SQLError)
 	message := sqlErr.Error()
@@ -719,7 +716,7 @@ func wasConnectionClosed(err error) bool {
 	case mysql.CRServerGone, mysql.CRServerLost:
 		return true
 	case mysql.ERQueryInterrupted:
-		return txClosed.MatchString(message)
+		return vterrors.TxClosed.MatchString(message)
 	default:
 		return false
 	}
diff --git a/go/vt/vtgate/scatter_conn_test.go b/go/vt/vtgate/scatter_conn_test.go
index dd485a2055e..276b4cad405 100644
--- a/go/vt/vtgate/scatter_conn_test.go
+++ b/go/vt/vtgate/scatter_conn_test.go
@@ -325,6 +325,14 @@ func TestReservedConnFail(t *testing.T) {
 	assert.NotEqual(t, oldRId, session.Session.ShardSessions[0].ReservedId, "should have recreated a reserved connection since the last connection was lost")
 	oldRId = session.Session.ShardSessions[0].ReservedId
 
+	sbc0.Queries = nil
+	sbc0.EphemeralShardErr = mysql.NewSQLError(mysql.ERQueryInterrupted, mysql.SSUnknownSQLState, "transaction 123 in use: for tx killer rollback")
+	_ = executeOnShardsReturnsErr(t, res, keyspace, sc, session, destinations)
+	assert.Equal(t, 2, len(sbc0.Queries), "one for the failed attempt, and one for the retry")
+	require.Equal(t, 1, len(session.ShardSessions))
+	assert.NotEqual(t, oldRId, session.Session.ShardSessions[0].ReservedId, "should have recreated a reserved connection since the last connection was lost")
+	oldRId = session.Session.ShardSessions[0].ReservedId
+
 	sbc0.Queries = nil
 	sbc0.EphemeralShardErr = vterrors.New(vtrpcpb.Code_CLUSTER_EVENT, "operation not allowed in state NOT_SERVING during query: query1")
 	_ = executeOnShardsReturnsErr(t, res, keyspace, sc, session, destinations)
@@ -420,6 +428,10 @@ func TestIsConnClosed(t *testing.T) {
 		"tx not found missing tx id",
 		mysql.NewSQLError(mysql.ERQueryInterrupted, mysql.SSUnknownSQLState, "transaction not found"),
 		false,
+	}, {
+		"tx getting killed by tx killer",
+		mysql.NewSQLError(mysql.ERQueryInterrupted, mysql.SSUnknownSQLState, "transaction 111 in use: for tx killer rollback"),
+		true,
 	}}
 
 	for _, tCase := range testCases {
diff --git a/go/vt/vttablet/tabletserver/tx_pool.go b/go/vt/vttablet/tabletserver/tx_pool.go
index 12e262e6b65..4673bc1432b 100644
--- a/go/vt/vttablet/tabletserver/tx_pool.go
+++ b/go/vt/vttablet/tabletserver/tx_pool.go
@@ -122,7 +122,7 @@ func (tp *TxPool) Shutdown(ctx context.Context) {
 
 func (tp *TxPool) transactionKiller() {
 	defer tp.env.LogError()
-	for _, conn := range tp.scp.GetOutdated(tp.Timeout(), "for tx killer rollback") {
+	for _, conn := range tp.scp.GetOutdated(tp.Timeout(), vterrors.TxKillerRollback) {
 		log.Warningf("killing transaction (exceeded timeout: %v): %s", tp.Timeout(), conn.String(tp.env.Config().SanitizeLogMessages))
 		switch {
 		case conn.IsTainted():