diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 53563c6c..40050890 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -70,14 +70,18 @@ jobs:
             os: ubuntu-latest
             python-version: 3.9
             tox-env: py39
-          - name: py3.9 with gmpy
+          - name: py3.10
             os: ubuntu-latest
-            python-version: 3.9
-            tox-env: gmpypy39
-          - name: py3.9 with gmpy2
+            python-version: '3.10'
+            tox-env: py310
+          - name: py3.10 with gmpy
             os: ubuntu-latest
-            python-version: 3.9
-            tox-env: gmpy2py39
+            python-version: '3.10'
+            tox-env: gmpypy310
+          - name: py3.10 with gmpy2
+            os: ubuntu-latest
+            python-version: '3.10'
+            tox-env: gmpy2py310
           - name: pypy
             os: ubuntu-latest
             python-version: pypy-2.7
diff --git a/tox.ini b/tox.ini
index 294eef34..7661d8cb 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,6 +1,6 @@
 
 [tox]
-envlist = py26, py27, py33, py34, py35, py36, py37, py38, py39, py, pypy, pypy3, gmpy2py27, gmpy2py39, gmpypy27, gmpypy39, codechecks
+envlist = py26, py27, py33, py34, py35, py36, py37, py38, py39, py310, py, pypy, pypy3, gmpy2py27, gmpy2py39, gmpy2py310, gmpypy27, gmpypy39, gmpypy310, codechecks
 
 [testenv]
 deps =
@@ -11,12 +11,12 @@ deps =
      py{26}: unittest2
      py{26}: hypothesis<3
      py{34}: attrs<21
-     py{26,27,34,35,36,37,38,39,py,py3}: pytest
-     py{27,34,35,36,37,38,39,py,py3}: hypothesis
-     gmpy2py{27,39}: gmpy2
-     gmpypy{27,39}: gmpy
-     gmpy{2py27,2py39,py27,py39}: pytest
-     gmpy{2py27,2py39,py27,py39}: hypothesis
+     py{26,27,34,35,36,37,38,39,310,py,py3}: pytest
+     py{27,34,35,36,37,38,39,310,py,py3}: hypothesis
+     gmpy2py{27,39,310}: gmpy2
+     gmpypy{27,39,310}: gmpy
+     gmpy{2py27,2py39,2py310,py27,py39,py310}: pytest
+     gmpy{2py27,2py39,2py310,py27,py39,py310}: hypothesis
 # six==1.9.0 comes from setup.py install_requires
      py27_old_six: six==1.9.0
      py27_old_six: pytest
@@ -50,12 +50,18 @@ basepython=python2.7
 [testenv:gmpypy39]
 basepython=python3.9
 
+[testenv:gmpypy310]
+basepython=python3.10
+
 [testenv:gmpy2py27]
 basepython=python2.7
 
 [testenv:gmpy2py39]
 basepython=python3.9
 
+[testenv:gmpy2py310]
+basepython=python3.10
+
 [testenv:instrumental]
 basepython = python2.7
 deps =