diff --git a/src/corePlugins.js b/src/corePlugins.js
index f92767e24cbe..4efc8cfae0e6 100644
--- a/src/corePlugins.js
+++ b/src/corePlugins.js
@@ -1814,13 +1814,16 @@ export let corePlugins = {
         font: (value) => {
           let [families, options = {}] =
             Array.isArray(value) && isPlainObject(value[1]) ? value : [value]
-          let { fontFeatureSettings } = options
+          let { fontFeatureSettings, fontVariationSettings } = options
 
           return {
             'font-family': Array.isArray(families) ? families.join(', ') : families,
             ...(fontFeatureSettings === undefined
               ? {}
               : { 'font-feature-settings': fontFeatureSettings }),
+            ...(fontVariationSettings === undefined
+              ? {}
+              : { 'font-variation-settings': fontVariationSettings }),
           }
         },
       },
diff --git a/src/css/preflight.css b/src/css/preflight.css
index 3029044290d5..fab875d95904 100644
--- a/src/css/preflight.css
+++ b/src/css/preflight.css
@@ -23,6 +23,7 @@
 3. Use a more readable tab size.
 4. Use the user's configured `sans` font-family by default.
 5. Use the user's configured `sans` font-feature-settings by default.
+6. Use the user's configured `sans` font-variation-settings by default.
 */
 
 html {
@@ -32,6 +33,7 @@ html {
   tab-size: 4; /* 3 */
   font-family: theme('fontFamily.sans', ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, "Noto Sans", sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", "Noto Color Emoji"); /* 4 */
   font-feature-settings: theme('fontFamily.sans[1].fontFeatureSettings', normal); /* 5 */
+  font-variation-settings: theme('fontFamily.sans[1].fontVariationSettings', normal); /* 6 */
 }
 
 /*
diff --git a/tests/__snapshots__/source-maps.test.js.snap b/tests/__snapshots__/source-maps.test.js.snap
index b1016e638e7c..32da0ae772dd 100644
--- a/tests/__snapshots__/source-maps.test.js.snap
+++ b/tests/__snapshots__/source-maps.test.js.snap
@@ -73,293 +73,294 @@ Array [
   "2:4-18 -> 19:2-18",
   "2:18 -> 20:0",
   "2:4 -> 22:0",
-  "2:18 -> 28:1",
-  "2:4 -> 30:0",
-  "2:4-18 -> 31:2-26",
-  "2:4-18 -> 32:2-40",
-  "2:4-18 -> 33:2-26",
-  "2:4-18 -> 34:2-21",
-  "2:4-18 -> 35:2-230",
-  "2:4-18 -> 36:2-39",
-  "2:18 -> 37:0",
-  "2:4 -> 39:0",
-  "2:18 -> 42:1",
-  "2:4 -> 44:0",
-  "2:4-18 -> 45:2-19",
-  "2:4-18 -> 46:2-30",
-  "2:18 -> 47:0",
-  "2:4 -> 49:0",
-  "2:18 -> 53:1",
-  "2:4 -> 55:0",
-  "2:4-18 -> 56:2-19",
-  "2:4-18 -> 57:2-24",
-  "2:4-18 -> 58:2-31",
-  "2:18 -> 59:0",
-  "2:4 -> 61:0",
-  "2:18 -> 63:1",
-  "2:4 -> 65:0",
-  "2:4-18 -> 66:2-35",
-  "2:18 -> 67:0",
-  "2:4 -> 69:0",
-  "2:18 -> 71:1",
-  "2:4 -> 73:0",
-  "2:4-18 -> 79:2-20",
-  "2:4-18 -> 80:2-22",
-  "2:18 -> 81:0",
-  "2:4 -> 83:0",
-  "2:18 -> 85:1",
-  "2:4 -> 87:0",
-  "2:4-18 -> 88:2-16",
-  "2:4-18 -> 89:2-26",
-  "2:18 -> 90:0",
-  "2:4 -> 92:0",
-  "2:18 -> 94:1",
-  "2:4 -> 96:0",
-  "2:4-18 -> 98:2-21",
-  "2:18 -> 99:0",
-  "2:4 -> 101:0",
-  "2:18 -> 104:1",
-  "2:4 -> 106:0",
-  "2:4-18 -> 110:2-121",
-  "2:4-18 -> 111:2-24",
-  "2:18 -> 112:0",
-  "2:4 -> 114:0",
-  "2:18 -> 116:1",
-  "2:4 -> 118:0",
-  "2:4-18 -> 119:2-16",
-  "2:18 -> 120:0",
-  "2:4 -> 122:0",
-  "2:18 -> 124:1",
-  "2:4 -> 126:0",
-  "2:4-18 -> 128:2-16",
-  "2:4-18 -> 129:2-16",
-  "2:4-18 -> 130:2-20",
-  "2:4-18 -> 131:2-26",
-  "2:18 -> 132:0",
-  "2:4 -> 134:0",
-  "2:4-18 -> 135:2-17",
-  "2:18 -> 136:0",
-  "2:4 -> 138:0",
-  "2:4-18 -> 139:2-13",
-  "2:18 -> 140:0",
-  "2:4 -> 142:0",
-  "2:18 -> 146:1",
-  "2:4 -> 148:0",
-  "2:4-18 -> 149:2-24",
-  "2:4-18 -> 150:2-31",
-  "2:4-18 -> 151:2-35",
-  "2:18 -> 152:0",
-  "2:4 -> 154:0",
-  "2:18 -> 158:1",
-  "2:4 -> 160:0",
-  "2:4-18 -> 165:2-30",
-  "2:4-18 -> 166:2-25",
+  "2:18 -> 29:1",
+  "2:4 -> 31:0",
+  "2:4-18 -> 32:2-26",
+  "2:4-18 -> 33:2-40",
+  "2:4-18 -> 34:2-26",
+  "2:4-18 -> 35:2-21",
+  "2:4-18 -> 36:2-230",
+  "2:4-18 -> 37:2-39",
+  "2:4-18 -> 38:2-41",
+  "2:18 -> 39:0",
+  "2:4 -> 41:0",
+  "2:18 -> 44:1",
+  "2:4 -> 46:0",
+  "2:4-18 -> 47:2-19",
+  "2:4-18 -> 48:2-30",
+  "2:18 -> 49:0",
+  "2:4 -> 51:0",
+  "2:18 -> 55:1",
+  "2:4 -> 57:0",
+  "2:4-18 -> 58:2-19",
+  "2:4-18 -> 59:2-24",
+  "2:4-18 -> 60:2-31",
+  "2:18 -> 61:0",
+  "2:4 -> 63:0",
+  "2:18 -> 65:1",
+  "2:4 -> 67:0",
+  "2:4-18 -> 68:2-35",
+  "2:18 -> 69:0",
+  "2:4 -> 71:0",
+  "2:18 -> 73:1",
+  "2:4 -> 75:0",
+  "2:4-18 -> 81:2-20",
+  "2:4-18 -> 82:2-22",
+  "2:18 -> 83:0",
+  "2:4 -> 85:0",
+  "2:18 -> 87:1",
+  "2:4 -> 89:0",
+  "2:4-18 -> 90:2-16",
+  "2:4-18 -> 91:2-26",
+  "2:18 -> 92:0",
+  "2:4 -> 94:0",
+  "2:18 -> 96:1",
+  "2:4 -> 98:0",
+  "2:4-18 -> 100:2-21",
+  "2:18 -> 101:0",
+  "2:4 -> 103:0",
+  "2:18 -> 106:1",
+  "2:4 -> 108:0",
+  "2:4-18 -> 112:2-121",
+  "2:4-18 -> 113:2-24",
+  "2:18 -> 114:0",
+  "2:4 -> 116:0",
+  "2:18 -> 118:1",
+  "2:4 -> 120:0",
+  "2:4-18 -> 121:2-16",
+  "2:18 -> 122:0",
+  "2:4 -> 124:0",
+  "2:18 -> 126:1",
+  "2:4 -> 128:0",
+  "2:4-18 -> 130:2-16",
+  "2:4-18 -> 131:2-16",
+  "2:4-18 -> 132:2-20",
+  "2:4-18 -> 133:2-26",
+  "2:18 -> 134:0",
+  "2:4 -> 136:0",
+  "2:4-18 -> 137:2-17",
+  "2:18 -> 138:0",
+  "2:4 -> 140:0",
+  "2:4-18 -> 141:2-13",
+  "2:18 -> 142:0",
+  "2:4 -> 144:0",
+  "2:18 -> 148:1",
+  "2:4 -> 150:0",
+  "2:4-18 -> 151:2-24",
+  "2:4-18 -> 152:2-31",
+  "2:4-18 -> 153:2-35",
+  "2:18 -> 154:0",
+  "2:4 -> 156:0",
+  "2:18 -> 160:1",
+  "2:4 -> 162:0",
   "2:4-18 -> 167:2-30",
-  "2:4-18 -> 168:2-30",
-  "2:4-18 -> 169:2-24",
-  "2:4-18 -> 170:2-19",
-  "2:4-18 -> 171:2-20",
-  "2:18 -> 172:0",
-  "2:4 -> 174:0",
-  "2:18 -> 176:1",
-  "2:4 -> 178:0",
-  "2:4-18 -> 180:2-22",
-  "2:18 -> 181:0",
-  "2:4 -> 183:0",
-  "2:18 -> 186:1",
-  "2:4 -> 188:0",
-  "2:4-18 -> 192:2-36",
-  "2:4-18 -> 193:2-39",
-  "2:4-18 -> 194:2-32",
-  "2:18 -> 195:0",
-  "2:4 -> 197:0",
-  "2:18 -> 199:1",
-  "2:4 -> 201:0",
-  "2:4-18 -> 202:2-15",
-  "2:18 -> 203:0",
-  "2:4 -> 205:0",
-  "2:18 -> 207:1",
-  "2:4 -> 209:0",
-  "2:4-18 -> 210:2-18",
-  "2:18 -> 211:0",
-  "2:4 -> 213:0",
-  "2:18 -> 215:1",
-  "2:4 -> 217:0",
-  "2:4-18 -> 218:2-26",
-  "2:18 -> 219:0",
-  "2:4 -> 221:0",
-  "2:18 -> 223:1",
-  "2:4 -> 225:0",
-  "2:4-18 -> 227:2-14",
-  "2:18 -> 228:0",
-  "2:4 -> 230:0",
-  "2:18 -> 233:1",
-  "2:4 -> 235:0",
-  "2:4-18 -> 236:2-39",
-  "2:4-18 -> 237:2-30",
-  "2:18 -> 238:0",
-  "2:4 -> 240:0",
-  "2:18 -> 242:1",
-  "2:4 -> 244:0",
-  "2:4-18 -> 245:2-26",
-  "2:18 -> 246:0",
-  "2:4 -> 248:0",
-  "2:18 -> 251:1",
-  "2:4 -> 253:0",
-  "2:4-18 -> 254:2-36",
-  "2:4-18 -> 255:2-23",
-  "2:18 -> 256:0",
-  "2:4 -> 258:0",
-  "2:18 -> 260:1",
-  "2:4 -> 262:0",
-  "2:4-18 -> 263:2-20",
-  "2:18 -> 264:0",
-  "2:4 -> 266:0",
-  "2:18 -> 268:1",
-  "2:4 -> 270:0",
-  "2:4-18 -> 283:2-11",
-  "2:18 -> 284:0",
-  "2:4 -> 286:0",
-  "2:4-18 -> 287:2-11",
-  "2:4-18 -> 288:2-12",
-  "2:18 -> 289:0",
-  "2:4 -> 291:0",
-  "2:4-18 -> 292:2-12",
-  "2:18 -> 293:0",
-  "2:4 -> 295:0",
-  "2:4-18 -> 298:2-18",
-  "2:4-18 -> 299:2-11",
-  "2:4-18 -> 300:2-12",
-  "2:18 -> 301:0",
-  "2:4 -> 303:0",
-  "2:18 -> 305:1",
-  "2:4 -> 307:0",
-  "2:4-18 -> 308:2-18",
-  "2:18 -> 309:0",
-  "2:4 -> 311:0",
-  "2:18 -> 314:1",
-  "2:4 -> 316:0",
-  "2:4-18 -> 318:2-20",
-  "2:4-18 -> 319:2-24",
-  "2:18 -> 320:0",
-  "2:4 -> 322:0",
-  "2:18 -> 324:1",
-  "2:4 -> 326:0",
-  "2:4-18 -> 328:2-17",
-  "2:18 -> 329:0",
-  "2:4 -> 331:0",
-  "2:18 -> 333:1",
-  "2:4 -> 334:0",
-  "2:4-18 -> 335:2-17",
-  "2:18 -> 336:0",
-  "2:4 -> 338:0",
-  "2:18 -> 342:1",
-  "2:4 -> 344:0",
-  "2:4-18 -> 352:2-24",
-  "2:4-18 -> 353:2-32",
-  "2:18 -> 354:0",
-  "2:4 -> 356:0",
-  "2:18 -> 358:1",
-  "2:4 -> 360:0",
-  "2:4-18 -> 362:2-17",
-  "2:4-18 -> 363:2-14",
-  "2:18 -> 364:0",
-  "2:4-18 -> 366:0-72",
-  "2:4 -> 367:0",
-  "2:4-18 -> 368:2-15",
-  "2:18 -> 369:0",
-  "2:4 -> 371:0",
-  "2:4-18 -> 372:2-26",
-  "2:4-18 -> 373:2-26",
-  "2:4-18 -> 374:2-21",
-  "2:4-18 -> 375:2-21",
-  "2:4-18 -> 376:2-16",
-  "2:4-18 -> 377:2-16",
+  "2:4-18 -> 168:2-25",
+  "2:4-18 -> 169:2-30",
+  "2:4-18 -> 170:2-30",
+  "2:4-18 -> 171:2-24",
+  "2:4-18 -> 172:2-19",
+  "2:4-18 -> 173:2-20",
+  "2:18 -> 174:0",
+  "2:4 -> 176:0",
+  "2:18 -> 178:1",
+  "2:4 -> 180:0",
+  "2:4-18 -> 182:2-22",
+  "2:18 -> 183:0",
+  "2:4 -> 185:0",
+  "2:18 -> 188:1",
+  "2:4 -> 190:0",
+  "2:4-18 -> 194:2-36",
+  "2:4-18 -> 195:2-39",
+  "2:4-18 -> 196:2-32",
+  "2:18 -> 197:0",
+  "2:4 -> 199:0",
+  "2:18 -> 201:1",
+  "2:4 -> 203:0",
+  "2:4-18 -> 204:2-15",
+  "2:18 -> 205:0",
+  "2:4 -> 207:0",
+  "2:18 -> 209:1",
+  "2:4 -> 211:0",
+  "2:4-18 -> 212:2-18",
+  "2:18 -> 213:0",
+  "2:4 -> 215:0",
+  "2:18 -> 217:1",
+  "2:4 -> 219:0",
+  "2:4-18 -> 220:2-26",
+  "2:18 -> 221:0",
+  "2:4 -> 223:0",
+  "2:18 -> 225:1",
+  "2:4 -> 227:0",
+  "2:4-18 -> 229:2-14",
+  "2:18 -> 230:0",
+  "2:4 -> 232:0",
+  "2:18 -> 235:1",
+  "2:4 -> 237:0",
+  "2:4-18 -> 238:2-39",
+  "2:4-18 -> 239:2-30",
+  "2:18 -> 240:0",
+  "2:4 -> 242:0",
+  "2:18 -> 244:1",
+  "2:4 -> 246:0",
+  "2:4-18 -> 247:2-26",
+  "2:18 -> 248:0",
+  "2:4 -> 250:0",
+  "2:18 -> 253:1",
+  "2:4 -> 255:0",
+  "2:4-18 -> 256:2-36",
+  "2:4-18 -> 257:2-23",
+  "2:18 -> 258:0",
+  "2:4 -> 260:0",
+  "2:18 -> 262:1",
+  "2:4 -> 264:0",
+  "2:4-18 -> 265:2-20",
+  "2:18 -> 266:0",
+  "2:4 -> 268:0",
+  "2:18 -> 270:1",
+  "2:4 -> 272:0",
+  "2:4-18 -> 285:2-11",
+  "2:18 -> 286:0",
+  "2:4 -> 288:0",
+  "2:4-18 -> 289:2-11",
+  "2:4-18 -> 290:2-12",
+  "2:18 -> 291:0",
+  "2:4 -> 293:0",
+  "2:4-18 -> 294:2-12",
+  "2:18 -> 295:0",
+  "2:4 -> 297:0",
+  "2:4-18 -> 300:2-18",
+  "2:4-18 -> 301:2-11",
+  "2:4-18 -> 302:2-12",
+  "2:18 -> 303:0",
+  "2:4 -> 305:0",
+  "2:18 -> 307:1",
+  "2:4 -> 309:0",
+  "2:4-18 -> 310:2-18",
+  "2:18 -> 311:0",
+  "2:4 -> 313:0",
+  "2:18 -> 316:1",
+  "2:4 -> 318:0",
+  "2:4-18 -> 320:2-20",
+  "2:4-18 -> 321:2-24",
+  "2:18 -> 322:0",
+  "2:4 -> 324:0",
+  "2:18 -> 326:1",
+  "2:4 -> 328:0",
+  "2:4-18 -> 330:2-17",
+  "2:18 -> 331:0",
+  "2:4 -> 333:0",
+  "2:18 -> 335:1",
+  "2:4 -> 336:0",
+  "2:4-18 -> 337:2-17",
+  "2:18 -> 338:0",
+  "2:4 -> 340:0",
+  "2:18 -> 344:1",
+  "2:4 -> 346:0",
+  "2:4-18 -> 354:2-24",
+  "2:4-18 -> 355:2-32",
+  "2:18 -> 356:0",
+  "2:4 -> 358:0",
+  "2:18 -> 360:1",
+  "2:4 -> 362:0",
+  "2:4-18 -> 364:2-17",
+  "2:4-18 -> 365:2-14",
+  "2:18 -> 366:0",
+  "2:4-18 -> 368:0-72",
+  "2:4 -> 369:0",
+  "2:4-18 -> 370:2-15",
+  "2:18 -> 371:0",
+  "2:4 -> 373:0",
+  "2:4-18 -> 374:2-26",
+  "2:4-18 -> 375:2-26",
+  "2:4-18 -> 376:2-21",
+  "2:4-18 -> 377:2-21",
   "2:4-18 -> 378:2-16",
-  "2:4-18 -> 379:2-17",
-  "2:4-18 -> 380:2-17",
-  "2:4-18 -> 381:2-15",
-  "2:4-18 -> 382:2-15",
-  "2:4-18 -> 383:2-20",
-  "2:4-18 -> 384:2-40",
-  "2:4-18 -> 385:2-17",
-  "2:4-18 -> 386:2-22",
-  "2:4-18 -> 387:2-24",
-  "2:4-18 -> 388:2-25",
-  "2:4-18 -> 389:2-26",
-  "2:4-18 -> 390:2-20",
-  "2:4-18 -> 391:2-29",
-  "2:4-18 -> 392:2-30",
-  "2:4-18 -> 393:2-40",
-  "2:4-18 -> 394:2-36",
-  "2:4-18 -> 395:2-29",
-  "2:4-18 -> 396:2-24",
-  "2:4-18 -> 397:2-32",
-  "2:4-18 -> 398:2-14",
-  "2:4-18 -> 399:2-20",
-  "2:4-18 -> 400:2-18",
-  "2:4-18 -> 401:2-19",
-  "2:4-18 -> 402:2-20",
-  "2:4-18 -> 403:2-16",
-  "2:4-18 -> 404:2-18",
-  "2:4-18 -> 405:2-15",
-  "2:4-18 -> 406:2-21",
-  "2:4-18 -> 407:2-23",
-  "2:4-18 -> 408:2-29",
-  "2:4-18 -> 409:2-27",
-  "2:4-18 -> 410:2-28",
-  "2:4-18 -> 411:2-29",
-  "2:4-18 -> 412:2-25",
-  "2:4-18 -> 413:2-26",
-  "2:4-18 -> 414:2-27",
-  "2:4 -> 415:2",
-  "2:18 -> 416:0",
-  "2:4 -> 418:0",
-  "2:4-18 -> 419:2-26",
-  "2:4-18 -> 420:2-26",
-  "2:4-18 -> 421:2-21",
-  "2:4-18 -> 422:2-21",
-  "2:4-18 -> 423:2-16",
-  "2:4-18 -> 424:2-16",
+  "2:4-18 -> 379:2-16",
+  "2:4-18 -> 380:2-16",
+  "2:4-18 -> 381:2-17",
+  "2:4-18 -> 382:2-17",
+  "2:4-18 -> 383:2-15",
+  "2:4-18 -> 384:2-15",
+  "2:4-18 -> 385:2-20",
+  "2:4-18 -> 386:2-40",
+  "2:4-18 -> 387:2-17",
+  "2:4-18 -> 388:2-22",
+  "2:4-18 -> 389:2-24",
+  "2:4-18 -> 390:2-25",
+  "2:4-18 -> 391:2-26",
+  "2:4-18 -> 392:2-20",
+  "2:4-18 -> 393:2-29",
+  "2:4-18 -> 394:2-30",
+  "2:4-18 -> 395:2-40",
+  "2:4-18 -> 396:2-36",
+  "2:4-18 -> 397:2-29",
+  "2:4-18 -> 398:2-24",
+  "2:4-18 -> 399:2-32",
+  "2:4-18 -> 400:2-14",
+  "2:4-18 -> 401:2-20",
+  "2:4-18 -> 402:2-18",
+  "2:4-18 -> 403:2-19",
+  "2:4-18 -> 404:2-20",
+  "2:4-18 -> 405:2-16",
+  "2:4-18 -> 406:2-18",
+  "2:4-18 -> 407:2-15",
+  "2:4-18 -> 408:2-21",
+  "2:4-18 -> 409:2-23",
+  "2:4-18 -> 410:2-29",
+  "2:4-18 -> 411:2-27",
+  "2:4-18 -> 412:2-28",
+  "2:4-18 -> 413:2-29",
+  "2:4-18 -> 414:2-25",
+  "2:4-18 -> 415:2-26",
+  "2:4-18 -> 416:2-27",
+  "2:4 -> 417:2",
+  "2:18 -> 418:0",
+  "2:4 -> 420:0",
+  "2:4-18 -> 421:2-26",
+  "2:4-18 -> 422:2-26",
+  "2:4-18 -> 423:2-21",
+  "2:4-18 -> 424:2-21",
   "2:4-18 -> 425:2-16",
-  "2:4-18 -> 426:2-17",
-  "2:4-18 -> 427:2-17",
-  "2:4-18 -> 428:2-15",
-  "2:4-18 -> 429:2-15",
-  "2:4-18 -> 430:2-20",
-  "2:4-18 -> 431:2-40",
-  "2:4-18 -> 432:2-17",
-  "2:4-18 -> 433:2-22",
-  "2:4-18 -> 434:2-24",
-  "2:4-18 -> 435:2-25",
-  "2:4-18 -> 436:2-26",
-  "2:4-18 -> 437:2-20",
-  "2:4-18 -> 438:2-29",
-  "2:4-18 -> 439:2-30",
-  "2:4-18 -> 440:2-40",
-  "2:4-18 -> 441:2-36",
-  "2:4-18 -> 442:2-29",
-  "2:4-18 -> 443:2-24",
-  "2:4-18 -> 444:2-32",
-  "2:4-18 -> 445:2-14",
-  "2:4-18 -> 446:2-20",
-  "2:4-18 -> 447:2-18",
-  "2:4-18 -> 448:2-19",
-  "2:4-18 -> 449:2-20",
-  "2:4-18 -> 450:2-16",
-  "2:4-18 -> 451:2-18",
-  "2:4-18 -> 452:2-15",
-  "2:4-18 -> 453:2-21",
-  "2:4-18 -> 454:2-23",
-  "2:4-18 -> 455:2-29",
-  "2:4-18 -> 456:2-27",
-  "2:4-18 -> 457:2-28",
-  "2:4-18 -> 458:2-29",
-  "2:4-18 -> 459:2-25",
-  "2:4-18 -> 460:2-26",
-  "2:4-18 -> 461:2-27",
-  "2:4 -> 462:2",
-  "2:18 -> 463:0",
+  "2:4-18 -> 426:2-16",
+  "2:4-18 -> 427:2-16",
+  "2:4-18 -> 428:2-17",
+  "2:4-18 -> 429:2-17",
+  "2:4-18 -> 430:2-15",
+  "2:4-18 -> 431:2-15",
+  "2:4-18 -> 432:2-20",
+  "2:4-18 -> 433:2-40",
+  "2:4-18 -> 434:2-17",
+  "2:4-18 -> 435:2-22",
+  "2:4-18 -> 436:2-24",
+  "2:4-18 -> 437:2-25",
+  "2:4-18 -> 438:2-26",
+  "2:4-18 -> 439:2-20",
+  "2:4-18 -> 440:2-29",
+  "2:4-18 -> 441:2-30",
+  "2:4-18 -> 442:2-40",
+  "2:4-18 -> 443:2-36",
+  "2:4-18 -> 444:2-29",
+  "2:4-18 -> 445:2-24",
+  "2:4-18 -> 446:2-32",
+  "2:4-18 -> 447:2-14",
+  "2:4-18 -> 448:2-20",
+  "2:4-18 -> 449:2-18",
+  "2:4-18 -> 450:2-19",
+  "2:4-18 -> 451:2-20",
+  "2:4-18 -> 452:2-16",
+  "2:4-18 -> 453:2-18",
+  "2:4-18 -> 454:2-15",
+  "2:4-18 -> 455:2-21",
+  "2:4-18 -> 456:2-23",
+  "2:4-18 -> 457:2-29",
+  "2:4-18 -> 458:2-27",
+  "2:4-18 -> 459:2-28",
+  "2:4-18 -> 460:2-29",
+  "2:4-18 -> 461:2-25",
+  "2:4-18 -> 462:2-26",
+  "2:4-18 -> 463:2-27",
+  "2:4 -> 464:2",
+  "2:18 -> 465:0",
 ]
 `;
 
diff --git a/tests/evaluateTailwindFunctions.test.js b/tests/evaluateTailwindFunctions.test.js
index f5d0822041d3..b584078de0ee 100644
--- a/tests/evaluateTailwindFunctions.test.js
+++ b/tests/evaluateTailwindFunctions.test.js
@@ -680,6 +680,72 @@ test('font-feature-settings values can be retrieved', () => {
   })
 })
 
+test('font-family values are retrieved without font-variation-settings', () => {
+  let input = css`
+    .heading-1 {
+      font-family: theme('fontFamily.sans');
+    }
+    .heading-2 {
+      font-family: theme('fontFamily.serif');
+    }
+    .heading-3 {
+      font-family: theme('fontFamily.mono');
+    }
+  `
+
+  let output = css`
+    .heading-1 {
+      font-family: Inter;
+    }
+    .heading-2 {
+      font-family: Times, serif;
+    }
+    .heading-3 {
+      font-family: Menlo, monospace;
+    }
+  `
+
+  return run(input, {
+    theme: {
+      fontFamily: {
+        sans: ['Inter', { fontVariationSettings: '"opsz" 32' }],
+        serif: [['Times', 'serif'], { fontVariationSettings: '"opsz" 32' }],
+        mono: ['Menlo, monospace', { fontVariationSettings: '"opsz" 32' }],
+      },
+    },
+  }).then((result) => {
+    expect(result.css).toMatchCss(output)
+    expect(result.warnings().length).toBe(0)
+  })
+})
+
+test('font-variation-settings values can be retrieved', () => {
+  let input = css`
+    .heading {
+      font-family: theme('fontFamily.sans');
+      font-variation-settings: theme('fontFamily.sans[1].fontVariationSettings');
+    }
+  `
+
+  let output = css`
+    .heading {
+      font-family: Inter;
+      font-variation-settings: 'opsz' 32;
+    }
+  `
+
+  return run(input, {
+    theme: {
+      fontFamily: {
+        sans: ['Inter', { fontVariationSettings: "'opsz' 32" }],
+      },
+    },
+  }).then((result) => {
+    expect(result.css).toMatchCss(output)
+    expect(result.warnings().length).toBe(0)
+  })
+})
+
 test('box-shadow values are joined when an array', () => {
   let input = css`
     .element {
diff --git a/tests/plugins/fontFamily.test.js b/tests/plugins/fontFamily.test.js
index 961689cf111a..faa05f4525ea 100644
--- a/tests/plugins/fontFamily.test.js
+++ b/tests/plugins/fontFamily.test.js
@@ -96,3 +96,43 @@ test('font-feature-settings can be provided when families are defined as an arra
     `)
   })
 })
+
+test('font-variation-settings can be provided when families are defined as a string', () => {
+  let config = {
+    content: [{ raw: html`<div class="font-sans"></div>` }],
+    theme: {
+      fontFamily: {
+        sans: ['Inter, sans-serif', { fontVariationSettings: '"opsz" 32' }],
+      },
+    },
+  }
+
+  return run('@tailwind utilities', config).then((result) => {
+    expect(result.css).toMatchCss(`
+      .font-sans {
+        font-family: Inter, sans-serif;
+        font-variation-settings: "opsz" 32;
+      }
+    `)
+  })
+})
+
+test('font-variation-settings can be provided when families are defined as an array', () => {
+  let config = {
+    content: [{ raw: html`<div class="font-sans"></div>` }],
+    theme: {
+      fontFamily: {
+        sans: [['Inter', 'sans-serif'], { fontVariationSettings: '"opsz" 32' }],
+      },
+    },
+  }
+
+  return run('@tailwind utilities', config).then((result) => {
+    expect(result.css).toMatchCss(`
+      .font-sans {
+        font-family: Inter, sans-serif;
+        font-variation-settings: "opsz" 32;
+      }
+    `)
+  })
+})
diff --git a/types/config.d.ts b/types/config.d.ts
index 9a5e0422f2cb..24607f11f495 100644
--- a/types/config.d.ts
+++ b/types/config.d.ts
@@ -165,7 +165,13 @@ interface ThemeConfig {
       string,
       | string
       | string[]
-      | [fontFamily: string | string[], configuration: Partial<{ fontFeatureSettings: string }>]
+      | [
+          fontFamily: string | string[],
+          configuration: Partial<{
+            fontFeatureSettings: string
+            fontVariationSettings: string
+          }>
+        ]
     >
   >
   fontSize: ResolvableTo<