diff --git a/compiler/rustc_trait_selection/src/traits/coherence.rs b/compiler/rustc_trait_selection/src/traits/coherence.rs
index 4e5e756dc4af4..28a69a0f5ad45 100644
--- a/compiler/rustc_trait_selection/src/traits/coherence.rs
+++ b/compiler/rustc_trait_selection/src/traits/coherence.rs
@@ -120,6 +120,48 @@ pub fn overlapping_impls(
     Some(overlap(selcx, skip_leak_check, impl1_def_id, impl2_def_id, overlap_mode).unwrap())
 }
 
+/// Given an impl_def_id that "positively" implement a trait, check if the "negative" holds.
+pub fn negative_impl_holds(tcx: TyCtxt<'_>, impl_def_id: DefId, overlap_mode: OverlapMode) -> bool {
+    debug!("negative_impl_holds(impl1_header={:?}, overlap_mode={:?})", impl_def_id, overlap_mode);
+    // `for<T> (Vec<u32>, T): Trait`
+    let header = tcx.impl_trait_ref(impl_def_id).unwrap();
+
+    let infcx = tcx
+        .infer_ctxt()
+        .with_opaque_type_inference(DefiningAnchor::Bubble)
+        .intercrate(true)
+        .build();
+
+    // `[?t]`
+    let infer_substs = infcx.fresh_substs_for_item(DUMMY_SP, impl_def_id);
+
+    // `(Vec<u32>, ?t): Trait`
+    let trait_ref = header.subst(tcx, infer_substs);
+
+    // `(Vec<u32>, ?t): !Trait`
+    let trait_pred = tcx.mk_predicate(ty::Binder::dummy(ty::PredicateKind::Clause(
+        ty::Clause::Trait(ty::TraitPredicate {
+            trait_ref,
+            constness: ty::BoundConstness::NotConst,
+            polarity: ty::ImplPolarity::Negative,
+        }),
+    )));
+
+    // Ideally we would use param_env(impl_def_id) but that's unsound today.
+    let param_env = ty::ParamEnv::empty();
+
+    let selcx = &mut SelectionContext::new(&infcx);
+    selcx
+        .evaluate_root_obligation(&Obligation::new(
+            tcx,
+            ObligationCause::dummy(),
+            param_env,
+            trait_pred,
+        ))
+        .expect("Overflow should be caught earlier in standard query mode")
+        .must_apply_modulo_regions()
+}
+
 fn with_fresh_ty_vars<'cx, 'tcx>(
     selcx: &mut SelectionContext<'cx, 'tcx>,
     param_env: ty::ParamEnv<'tcx>,
diff --git a/compiler/rustc_trait_selection/src/traits/mod.rs b/compiler/rustc_trait_selection/src/traits/mod.rs
index 8d831dca6e309..365ff0b903062 100644
--- a/compiler/rustc_trait_selection/src/traits/mod.rs
+++ b/compiler/rustc_trait_selection/src/traits/mod.rs
@@ -41,7 +41,9 @@ pub use self::ImplSource::*;
 pub use self::ObligationCauseCode::*;
 pub use self::SelectionError::*;
 
-pub use self::coherence::{add_placeholder_note, orphan_check, overlapping_impls};
+pub use self::coherence::{
+    add_placeholder_note, negative_impl_holds, orphan_check, overlapping_impls,
+};
 pub use self::coherence::{OrphanCheckErr, OverlapResult};
 pub use self::engine::{ObligationCtxt, TraitEngineExt};
 pub use self::fulfill::{FulfillmentContext, PendingPredicateObligation};
diff --git a/compiler/rustc_trait_selection/src/traits/specialize/specialization_graph.rs b/compiler/rustc_trait_selection/src/traits/specialize/specialization_graph.rs
index 5f036ce53b7b8..4bcf4735feb97 100644
--- a/compiler/rustc_trait_selection/src/traits/specialize/specialization_graph.rs
+++ b/compiler/rustc_trait_selection/src/traits/specialize/specialization_graph.rs
@@ -226,6 +226,22 @@ fn overlap_check_considering_specialization<'tcx>(
         return Ok(OverlapResult::SpecializeAll(replace_children));
     }
 
+    if overlap_mode.use_negative_impl()
+        && tcx.impl_polarity(impl_def_id) == ty::ImplPolarity::Positive
+        && traits::negative_impl_holds(tcx, impl_def_id, overlap_mode)
+    {
+        let trait_ref = tcx.impl_trait_ref(impl_def_id).unwrap().skip_binder();
+        let self_ty = trait_ref.self_ty();
+
+        return Err(OverlapError {
+            with_impl: impl_def_id,
+            trait_ref,
+            self_ty: self_ty.has_concrete_skeleton().then_some(self_ty),
+            intercrate_ambiguity_causes: Default::default(),
+            involves_placeholder: false,
+        });
+    }
+
     Ok(OverlapResult::NoOverlap(last_lint))
 }
 
diff --git a/tests/ui/coherence/coherence-overlap-negative-cycles.rs b/tests/ui/coherence/coherence-overlap-negative-cycles.rs
new file mode 100644
index 0000000000000..f11a0fe7a1da1
--- /dev/null
+++ b/tests/ui/coherence/coherence-overlap-negative-cycles.rs
@@ -0,0 +1,17 @@
+#![feature(trivial_bounds)]
+#![feature(negative_impls)]
+#![feature(rustc_attrs)]
+#![feature(with_negative_coherence)]
+#![allow(trivial_bounds)]
+
+#[rustc_strict_coherence]
+trait MyTrait {}
+
+struct Foo {}
+
+impl !MyTrait for Foo {}
+
+impl MyTrait for Foo where Foo: MyTrait {}
+//~^ ERROR: conflicting implementations of trait `MyTrait`
+
+fn main() {}
diff --git a/tests/ui/coherence/coherence-overlap-negative-cycles.stderr b/tests/ui/coherence/coherence-overlap-negative-cycles.stderr
new file mode 100644
index 0000000000000..672c6520dbf63
--- /dev/null
+++ b/tests/ui/coherence/coherence-overlap-negative-cycles.stderr
@@ -0,0 +1,12 @@
+error[E0119]: conflicting implementations of trait `MyTrait` for type `Foo`
+  --> $DIR/coherence-overlap-negative-cycles.rs:14:1
+   |
+LL | impl MyTrait for Foo where Foo: MyTrait {}
+   | ^^^^^^^^^^^^^^^^^^^^
+   | |
+   | first implementation here
+   | conflicting implementation for `Foo`
+
+error: aborting due to previous error
+
+For more information about this error, try `rustc --explain E0119`.