diff --git a/src/tools/compiletest/src/runtest.rs b/src/tools/compiletest/src/runtest.rs
index bc80c8246ad0f..b1ca193c4a38e 100644
--- a/src/tools/compiletest/src/runtest.rs
+++ b/src/tools/compiletest/src/runtest.rs
@@ -2332,6 +2332,20 @@ impl<'test> TestCx<'test> {
         // eg. /home/user/rust/build
         normalize_path(parent_build_dir, "$BUILD_DIR");
 
+        // e.g. /home/user/.cargo
+        if let Ok(cargo_home) = home::cargo_home() {
+            let mut from = cargo_home.display().to_string();
+            if json {
+                from = from.replace("\\", "\\\\");
+            }
+            // In CI, `$CARGO_HOME` is `/cargo`, but some paths in output contain `.../cargo...`
+            // Try to normalize only paths beginning with `$CARGO_HOME`
+            for prefix in [' ', '\n', '\'', '"'] {
+                normalized =
+                    normalized.replace(&format!("{prefix}{from}"), &format!("{prefix}{from}"));
+            }
+        }
+
         if json {
             // escaped newlines in json strings should be readable
             // in the stderr files. There's no point int being correct,
diff --git a/tests/ui/issues/issue-21763.rs b/tests/ui/issues/issue-21763.rs
index 1d0a0705cbbd9..5beb1d8b8c476 100644
--- a/tests/ui/issues/issue-21763.rs
+++ b/tests/ui/issues/issue-21763.rs
@@ -1,7 +1,5 @@
 // Regression test for HashMap only impl'ing Send/Sync if its contents do
 
-//@ normalize-stderr-test: "\S+[\\/]hashbrown\S+" -> "$$HASHBROWN_SRC_LOCATION"
-
 use std::collections::HashMap;
 use std::rc::Rc;
 
diff --git a/tests/ui/issues/issue-21763.stderr b/tests/ui/issues/issue-21763.stderr
index 135b705eeeff2..c69c0a2d40f31 100644
--- a/tests/ui/issues/issue-21763.stderr
+++ b/tests/ui/issues/issue-21763.stderr
@@ -1,5 +1,5 @@
 error[E0277]: `Rc<()>` cannot be sent between threads safely
-  --> $DIR/issue-21763.rs:11:11
+  --> $DIR/issue-21763.rs:9:11
    |
 LL |     foo::<HashMap<Rc<()>, Rc<()>>>();
    |           ^^^^^^^^^^^^^^^^^^^^^^^ `Rc<()>` cannot be sent between threads safely
@@ -8,11 +8,11 @@ LL |     foo::<HashMap<Rc<()>, Rc<()>>>();
    = note: required because it appears within the type `(Rc<()>, Rc<()>)`
    = note: required for `hashbrown::raw::RawTable<(Rc<()>, Rc<()>)>` to implement `Send`
 note: required because it appears within the type `hashbrown::map::HashMap<Rc<()>, Rc<()>, RandomState>`
-  --> $HASHBROWN_SRC_LOCATION
+  --> $CARGO_HOME/registry/src/index.crates.io-6f17d22bba15001f/hashbrown-0.15.0/src/map.rs:185:12
 note: required because it appears within the type `HashMap<Rc<()>, Rc<()>>`
   --> $SRC_DIR/std/src/collections/hash/map.rs:LL:COL
 note: required by a bound in `foo`
-  --> $DIR/issue-21763.rs:8:11
+  --> $DIR/issue-21763.rs:6:11
    |
 LL | fn foo<T: Send>() {}
    |           ^^^^ required by this bound in `foo`