diff --git a/.changeset/css-bundle-skip-packages.md b/.changeset/css-bundle-skip-packages.md
new file mode 100644
index 00000000000..9afad9e2e9d
--- /dev/null
+++ b/.changeset/css-bundle-skip-packages.md
@@ -0,0 +1,5 @@
+---
+"@remix-run/dev": patch
+---
+
+Improve performance of CSS bundle build by skipping compilation of Remix/React packages that are known not to contain CSS imports
diff --git a/packages/remix-dev/compiler/css/compiler.ts b/packages/remix-dev/compiler/css/compiler.ts
index 9517a3aa9e5..cc56b0dc7fb 100644
--- a/packages/remix-dev/compiler/css/compiler.ts
+++ b/packages/remix-dev/compiler/css/compiler.ts
@@ -79,6 +79,10 @@ const createEsbuildConfig = (ctx: Context): esbuild.BuildOptions => {
       absoluteCssUrlsPlugin(),
       externalPlugin(/^https?:\/\//, { sideEffects: false }),
       mdxPlugin(ctx),
+      // Skip compilation of common packages/scopes known not to include CSS imports
+      emptyModulesPlugin(ctx, /^(@remix-run|react|react-dom)(\/.*)?$/, {
+        includeNodeModules: true,
+      }),
       emptyModulesPlugin(ctx, /\.server(\.[jt]sx?)?$/),
       externalPlugin(/^node:.*/, { sideEffects: false }),
     ],
diff --git a/packages/remix-dev/compiler/plugins/emptyModules.ts b/packages/remix-dev/compiler/plugins/emptyModules.ts
index a8b34c00e6f..9ae03d6c74a 100644
--- a/packages/remix-dev/compiler/plugins/emptyModules.ts
+++ b/packages/remix-dev/compiler/plugins/emptyModules.ts
@@ -9,18 +9,21 @@ import type { Context } from "../context";
  */
 export function emptyModulesPlugin(
   { config }: Context,
-  filter: RegExp
+  filter: RegExp,
+  { includeNodeModules = false } = {}
 ): esbuild.Plugin {
   return {
     name: "empty-modules",
     setup(build) {
       build.onResolve({ filter }, (args) => {
-        let resolved = path.resolve(args.resolveDir, args.path);
         if (
+          includeNodeModules ||
           // Limit this behavior to modules found in only the `app` directory.
           // This allows node_modules to use the `.server.js` and `.client.js`
           // naming conventions with different semantics.
-          resolved.startsWith(config.appDirectory)
+          path
+            .resolve(args.resolveDir, args.path)
+            .startsWith(config.appDirectory)
         ) {
           return { path: args.path, namespace: "empty-module" };
         }