diff --git a/Python/sysmodule.c b/Python/sysmodule.c
index e70c5d0df29d8f3..5bdfca549e08d1a 100644
--- a/Python/sysmodule.c
+++ b/Python/sysmodule.c
@@ -2287,7 +2287,7 @@ sys_activate_stack_trampoline_impl(PyObject *module, const char *backend)
 /*[clinic end generated code: output=5783cdeb51874b43 input=a12df928758a82b4]*/
 {
 #ifdef PY_HAVE_PERF_TRAMPOLINE
-#ifdef _Py_TIER2
+#ifdef _Py_JIT
     _PyOptimizerObject* optimizer = _Py_GetOptimizer();
     if (optimizer != NULL) {
         PyErr_SetString(PyExc_ValueError, "Cannot activate the perf trampoline if the JIT is active");