diff --git a/CHANGELOG.md b/CHANGELOG.md
index 43aa4482e26..eca414a6128 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -20,6 +20,8 @@ For experimental package changes, see the [experimental CHANGELOG](experimental/
 
 ### :bug: (Bug Fix)
 
+* fix(core): added falsy check to make otel core work with browser where webpack config had process as false or null [#3613](https://github.com/open-telemetry/opentelemetry-js/issues/3613) @ravindra-dyte
+
 ### :books: (Refine Doc)
 
 ### :house: (Internal)
diff --git a/packages/opentelemetry-core/src/utils/environment.ts b/packages/opentelemetry-core/src/utils/environment.ts
index 01da17f293a..5d529d08a94 100644
--- a/packages/opentelemetry-core/src/utils/environment.ts
+++ b/packages/opentelemetry-core/src/utils/environment.ts
@@ -333,7 +333,7 @@ export function parseEnvironment(values: RAW_ENVIRONMENT): ENVIRONMENT {
  * populating default values.
  */
 export function getEnvWithoutDefaults(): ENVIRONMENT {
-  return typeof process !== 'undefined'
+  return typeof process !== 'undefined' && process && process.env
     ? parseEnvironment(process.env as RAW_ENVIRONMENT)
     : parseEnvironment(_globalThis as typeof globalThis & RAW_ENVIRONMENT);
 }
diff --git a/packages/opentelemetry-sdk-trace-web/test/NodeGlobalsFoolProofing.test.ts b/packages/opentelemetry-sdk-trace-web/test/NodeGlobalsFoolProofing.test.ts
new file mode 100644
index 00000000000..19090be5656
--- /dev/null
+++ b/packages/opentelemetry-sdk-trace-web/test/NodeGlobalsFoolProofing.test.ts
@@ -0,0 +1,84 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+import {
+  context,
+  propagation,
+  trace,
+  ProxyTracerProvider,
+} from '@opentelemetry/api';
+import { Resource } from '@opentelemetry/resources';
+import { Tracer } from '@opentelemetry/sdk-trace-base';
+import * as assert from 'assert';
+import { StackContextManager, WebTracerProvider } from '../src';
+
+describe('Node Globals Foolproofing', () => {
+  const originalProcess = globalThis?.process;
+  before(() => {
+    Object.assign(globalThis, { process: false });
+  });
+
+  after(() => {
+    Object.assign(globalThis, { process: originalProcess });
+  });
+
+  beforeEach(() => {
+    context.disable();
+    trace.disable();
+    propagation.disable();
+  });
+
+  it('Can get TraceProvider without node globals such as process', () => {
+    const propagator = propagation['_getGlobalPropagator']();
+    const tracerProvider = new WebTracerProvider();
+    tracerProvider.register({
+      propagator: null,
+    });
+
+    assert.strictEqual(
+      propagation['_getGlobalPropagator'](),
+      propagator,
+      'propagator should not change'
+    );
+
+    assert.ok(context['_getContextManager']() instanceof StackContextManager);
+    const apiTracerProvider = trace.getTracerProvider() as ProxyTracerProvider;
+    assert.ok(apiTracerProvider.getDelegate() === tracerProvider);
+  });
+
+  it('Can get TraceProvider with custom id generator and without node globals such as process', () => {
+    const getRandomString = (length: number) => {
+      const alphanumericsList = 'abcdefghijklmnopqrstuvwxyz0123456789'.split(
+        ''
+      );
+      alphanumericsList.sort(() => 0.5 - Math.random());
+
+      return alphanumericsList.slice(0, length).join('');
+    };
+
+    const tracer = new WebTracerProvider({
+      resource: new Resource({
+        'service.name': 'web-core',
+      }),
+      idGenerator: {
+        generateTraceId: () => getRandomString(32),
+        generateSpanId: () => getRandomString(16),
+      },
+    }).getTracer('default');
+
+    assert.ok(tracer instanceof Tracer);
+  });
+});