diff --git a/CHANGELOG.md b/CHANGELOG.md
index 27fff26e3..f45ab0a30 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -23,6 +23,10 @@ OpenTelemetry Go Automatic Instrumentation adheres to [Semantic Versioning](http
 - Support `golang.org/x/net` `0.34.0`. ([#1552](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/1552))
 - Support `google.golang.org/grpc` `1.71.0-dev`. ([#1467](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/1467))
 
+### Changed
+
+- Preemptively drop support for the `traceglobal` probe when `Go >= 1.24` is used. ([#1573](https://github.com/open-telemetry/opentelemetry-go-instrumentation/pull/1573))
+
 ## [v0.19.0-alpha] - 2024-12-05
 
 ### Added
diff --git a/COMPATIBILITY.md b/COMPATIBILITY.md
index 87bd6e0e7..71078970f 100644
--- a/COMPATIBILITY.md
+++ b/COMPATIBILITY.md
@@ -9,7 +9,11 @@ Supported versions of [`otel`]:
 
 - `v0.14.0` to `v1.33.0`
 
+**Note**: Versions of `go.opentelemetry.io/otel < v1.33.0` are not supported
+when using Go >= `1.24`. See [this issue] for details.
+
 [`otel`]: https://pkg.go.dev/go.opentelemetry.io/otel
+[this issue]: https://github.com/open-telemetry/opentelemetry-go-instrumentation/issues/1318
 
 ## Instrumented Library Compatibility
 
diff --git a/internal/pkg/instrumentation/bpf/go.opentelemetry.io/otel/traceglobal/probe.go b/internal/pkg/instrumentation/bpf/go.opentelemetry.io/otel/traceglobal/probe.go
index e8da60e6a..780ae4cc0 100644
--- a/internal/pkg/instrumentation/bpf/go.opentelemetry.io/otel/traceglobal/probe.go
+++ b/internal/pkg/instrumentation/bpf/go.opentelemetry.io/otel/traceglobal/probe.go
@@ -39,6 +39,7 @@ const (
 	// Minimum version of go.opentelemetry.io/otel that supports using the
 	// go.opentelemetry.io/auto/sdk in the global API.
 	minAutoSDK = "1.33.0"
+	minGoMaps  = "1.24.0"
 )
 
 var (
@@ -56,6 +57,14 @@ var (
 		),
 		FailureMode: probe.FailureModeIgnore,
 	}
+	goWithoutSwissMaps = probe.PackageConstrainst{
+		Package: "std",
+		Constraints: version.MustConstraints(
+			version.NewConstraint(fmt.Sprintf("< %s", minGoMaps)),
+		),
+		// Warn in logs that this is not supported.
+		FailureMode: probe.FailureModeWarn,
+	}
 )
 
 // New returns a new [probe.Probe].
@@ -151,6 +160,7 @@ func New(logger *slog.Logger) probe.Probe {
 					ReturnProbe: "uprobe_Start_Returns",
 					PackageConstrainsts: []probe.PackageConstrainst{
 						otelWithoutAutoSDK,
+						goWithoutSwissMaps,
 					},
 				},
 				{
@@ -158,6 +168,7 @@ func New(logger *slog.Logger) probe.Probe {
 					EntryProbe: "uprobe_End",
 					PackageConstrainsts: []probe.PackageConstrainst{
 						otelWithoutAutoSDK,
+						goWithoutSwissMaps,
 					},
 				},
 				{
@@ -166,6 +177,7 @@ func New(logger *slog.Logger) probe.Probe {
 					FailureMode: probe.FailureModeIgnore,
 					PackageConstrainsts: []probe.PackageConstrainst{
 						otelWithoutAutoSDK,
+						goWithoutSwissMaps,
 					},
 				},
 				{
@@ -174,6 +186,7 @@ func New(logger *slog.Logger) probe.Probe {
 					FailureMode: probe.FailureModeIgnore,
 					PackageConstrainsts: []probe.PackageConstrainst{
 						otelWithoutAutoSDK,
+						goWithoutSwissMaps,
 					},
 				},
 				{
@@ -182,6 +195,7 @@ func New(logger *slog.Logger) probe.Probe {
 					FailureMode: probe.FailureModeIgnore,
 					PackageConstrainsts: []probe.PackageConstrainst{
 						otelWithoutAutoSDK,
+						goWithoutSwissMaps,
 					},
 				},
 			},