diff --git a/.gitignore b/.gitignore
index b264f63b..48cca61b 100644
--- a/.gitignore
+++ b/.gitignore
@@ -3,8 +3,11 @@
 config.yml
 creds.json
 
-# Built schema files during test
+# Dist and test artifact files
+publish/**
 *.schema.json
+*.manifest.csv
+*.test.xlsx
 
 # Misc
 .Rhistory
diff --git a/NF.csv b/NF.csv
index 6109e6ba..a6c5d902 100644
--- a/NF.csv
+++ b/NF.csv
@@ -94,6 +94,9 @@ Optical Coherence Tomography,"Optical Coherence Tomography (OCT) combines the pr
 CUT&RUN,"Cleavage Under Targets and Release Using Nuclease (CUT&RUN) is a chromatin profiling strategy in which antibody-targeted controlled cleavage by micrococcal nuclease releases specific protein-DNA complexes into the supernatant for paired-end DNA sequencing. (doi:10.7554/eLife.21856)",,,FALSE,,assay,,,,CUT_RUN,Class,Assay,Assay,Epigenetics_Assay,,,
 3D Imaging,"Technique to produce 3D images to visualize important structures in great detail. To produce 3D images, many scans are made, and then combined by computers to produce a 3D model, which can then be manipulated. 3D ultrasounds are produced using a somewhat similar technique.",,Assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C18485,assay,,,,3D_Imaging,Class,Assay,Assay,Imaging_Assay,,,
 High Frequency Ultrasound,"High frequency ultrasound (HFUS) is an imaging modality that can give greater resolution of surface changes in skin (review in PMID:24583666)",,Assay,FALSE,,assay,,,,High_Frequency_Ultrasound,Class,Assay,Assay,Imaging_Assay,,,
+Dynamic Light Scattering,"Dynamic Light Scattering (DLS), also known as photocorrelation spectroscopy, is a method for determining the size distribution of a sample of small particles in solution by illuminating the sample with a light source (usually a laser) and measuring the time-dependent fluctuations in the intensity of the scattered light caused by Brownian motion.",,Assay,FALSE,http://purl.obolibrary.org/obo/CHMO_0000167,assay,,,,Dynamic_Light_Scattering,Class,Assay,Assay,Light_Scattering_Assay,,,
+Static Light Scattering,"Static Light Scattering is a method for determining structure by measuring the total or time-averaged scattering intensity of scattered visible light as a function of angle.",,Assay,FALSE,http://purl.obolibrary.org/obo/CHMO_0000180,assay,,,,Static_Light_Scattering,Class,Assay,Assay,Light_Scattering_Assay,,,
+Light Scattering Assay,"A method for determining structure by measuring the change in direction or energy of scattered visible light. Light is scattered by the electrons surrounding the atomic nuclei in the sample.",,Assay,FALSE,http://purl.obolibrary.org/obo/CHMO_0000166,assay,,,,Light_Scattering_Assay,Class,Assay,Assay,Spectroscopy,,,
 channel,Fluorescent color labeling for an array,"Cy5, Cy3","",TRUE,"",array,,"","",Channel,"",Assay,Assay_Parameter,"","","",""
 photograph,An image recorded by a camera.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C86035,assay,,"","",Photograph,"",Assay,Assay_Parameter,"","","",""
 MRISequence,The scanning sequence/modality that is used for a conventional MRI scan.,"T1-weighted,T2-weighted,PD-weighted,Short Tau Inversion Recovery","",FALSE,Sage Bionetworks,experimentalData,,"","",MRI_Sequence,Class,Assay,Assay_Parameter,"","","",""
@@ -202,7 +205,7 @@ Cherry Imaging FACE Platform,"(From vendor) A micro-ultrasound imaging system fo
 LifeViz Micro System,"(From vendor) Portable 3D imaging system for skin microstructure analysis.",,,FALSE,https://www.quantificare.com/3d-photography-systems_old/lifeviz-micro/,platform,,,,LifeViz_Micro_System,Class,Assay,Platform,Platform,,,
 LifeViz Infinity System,"(From vendor) All-in-one 3D imaging system for face, body and breast.",,,FALSE,https://www.quantificare.com/3d-photography-systems_old/lifeviz-infinity/,platform,,,,LifeViz_Infinity_System,Class,Assay,Platform,Platform,,,
 drugScreenType,String describing general class of drug screen,"singleMolecule, smallMoleculeLibraryScreen, combinationLibraryScreen, combinationScreen",,FALSE,,compoundScreen,,,,drugScreenType,Property,Assay,annotationProperty,,,,
-assay,The technology used to generate the data in this file,"elevated plus maze test, open field test, rotarod performance test, mRNAcounts, high content screen, Immunocytochemistry, immunofluorescence, autoradiography, electrochemiluminescence, Real Time PCR, in vivo tumor growth, scale, Blood Chemistry Measurement, in vivo bioluminescence, immunohistochemistry, NOMe-Seq, FIA-MSMS, UPLC-MSMS, HPLC-MSMS, liquid chromatography-electrochemical detection, rnaSeq, mirnaSeq, LC-MSMS, LC-MS, lncrnaSeq, Whole Exome Sequencing, Sanger sequencing, ChIPSeq, rnaArray, snpArray, methylationArray, mirnaArray, bisulfiteSeq, ATACSeq, HI-C, errBisulfiteSeq, ISOSeq, westernBlot, wholeGenomeSeq, polymeraseChainReaction, cellViabilityAssay, atomicForceMicroscopy, brightfieldMicroscopy, tractionForceMicroscopy, nextGenerationTargetedSequencing, jumpingLibrary, MIB/MS, scCGIseq, MudPIT, questionnaire, DNA optical mapping, oxBS-Seq, Ribo-Seq, Positron Emission Tomography, RPPA, ELISA, LTP, LFP, whole-cell patch clamp, sandwich ELISA, Laser Speckle Imaging, Genotyping, TMT quantitation, label free mass spectrometry, cell count, reporter gene assay, Single Cell RNA Sequencing, spatial transcriptomics, Conventional MRI, Functional MRI, Magnetic Resonance Spectroscopy, 2D Incucyte, 2D CellTiter-Glo, 3D microtissue viability, in vivo PDX viability, 2D AlamarBlue fluorescence, 2D AlamarBlue absorbance, rheometry, FTIR Spectroscopy, differential scanning calorimetry, Gel filtration chromatography, Massively Parallel Reporter Assay,Riccardi and Ablon scales,Spatial Frequency Domain Imaging,Optical Coherence Tomography,CUT&RUN,High Frequency Ultrasound, 3D Imaging",,TRUE,,experimentalData,,,,assayType,Property,Assay,annotationProperty,,Assay,one,
+assay,The technology used to generate the data in this file,"elevated plus maze test, open field test, rotarod performance test, mRNAcounts, high content screen, Immunocytochemistry, immunofluorescence, autoradiography, electrochemiluminescence, Real Time PCR, in vivo tumor growth, scale, Blood Chemistry Measurement, in vivo bioluminescence, immunohistochemistry, NOMe-Seq, FIA-MSMS, UPLC-MSMS, HPLC-MSMS, liquid chromatography-electrochemical detection, rnaSeq, mirnaSeq, LC-MSMS, LC-MS, lncrnaSeq, Whole Exome Sequencing, Sanger sequencing, ChIPSeq, rnaArray, snpArray, methylationArray, mirnaArray, bisulfiteSeq, ATACSeq, HI-C, errBisulfiteSeq, ISOSeq, westernBlot, wholeGenomeSeq, polymeraseChainReaction, cellViabilityAssay, atomicForceMicroscopy, brightfieldMicroscopy, tractionForceMicroscopy, nextGenerationTargetedSequencing, jumpingLibrary, MIB/MS, scCGIseq, MudPIT, questionnaire, DNA optical mapping, oxBS-Seq, Ribo-Seq, Positron Emission Tomography, RPPA, ELISA, LTP, LFP, whole-cell patch clamp, sandwich ELISA, Laser Speckle Imaging, Genotyping, TMT quantitation, label free mass spectrometry, cell count, reporter gene assay, Single Cell RNA Sequencing, spatial transcriptomics, Conventional MRI, Functional MRI, Magnetic Resonance Spectroscopy, 2D Incucyte, 2D CellTiter-Glo, 3D microtissue viability, in vivo PDX viability, 2D AlamarBlue fluorescence, 2D AlamarBlue absorbance, rheometry, FTIR Spectroscopy, differential scanning calorimetry, Gel filtration chromatography, Massively Parallel Reporter Assay,Riccardi and Ablon scales,Spatial Frequency Domain Imaging,Optical Coherence Tomography,CUT&RUN,High Frequency Ultrasound, 3D Imaging,Dynamic Light Scattering,Static Light Scattering",,TRUE,,experimentalData,,,,assayType,Property,Assay,annotationProperty,,Assay,one,
 platform,"A sequencing platform, microscope, spectroscope/plate reader, or other platform for collecting data.","Illumina HiSeq 3000, Illumina HiSeq 2500, Illumina HiSeq 4000, Illumina NextSeq 500, Illumina HiSeq 2000, Illumina MiSeq, Zeiss LSM 980, Affymetrix Genome-Wide Human SNP 5.0 Array, Affymetrix Genome-Wide Human SNP 6.0 Array, PacBio RS II, Illumina Genome Analyzer IIx, Illumina HumanOmni1-Quadv1.0, Illumina 1M, Illumina h650, Illumina Omni2pt5M, Illumina Omni5M, Illumina MouseWG-6 v2.0 expression beadchip, Perlegen 300Karray, Agilent 44Karray, Illumina WholeGenome DASL, Illumina HumanHap300, Nanostring Counter, LTQ Orbitrap XL, Illumina HumanMethylation450, Illumina Infinium MethylationEPIC BeadChip, Affymetrix U133AB, Affymetrix Human Gene 1.0 ST Array, Affymetrix Human Genome U133 Plus 2.0 Array, Illumina HiSeq X, Bionano Irys, Infinium HumanOmniExpressExome, Illumina NextSeq 550, Illumina NextSeq 1000, Illumina NextSeq 2000, PacBio Sequel IIe System, PacBio Sequel II System, Nanostring GeoMx, LI-COR Odyssey CLx, Spectramax M Series, Olympus DP80, Orbitrap Fusion Lumos Tribrid, Illumina NovaSeq 6000, Chromium X,EnVision 2103 Multiplate Reader,Vectra H1 3D Imaging System,Vevo 3100 Imaging System,10x Visium Spatial Gene Expression,Cherry Imaging TRACE Platform,Cherry Imaging FACE Platform,LifeViz Micro System,LifeViz Infinity System",,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=read_group&anchor=platform,experimentalData,,,,platform,Property,Assay,annotationProperty,,Platform,,
 targetCaptureKitID,"A unique identifier for the kit used to construct a genomic library using target capture-based techniques, which should be composed of the vendor name, kit name and kit version.",,,TRUE,http://purl.obolibrary.org/obo/NCIT_C177583,experimentalData,,,,targetCaptureKitID,Property,Assay,annotationProperty,,,,"For WES processing, the target BED used could be provided based on the target capture kit."
 libraryID,,,,TRUE,,experimentalData,,,,libraryID,Property,Assay,annotationProperty,,,,
@@ -225,6 +228,225 @@ readDepth,"If available, the coverage statistic as output from bedtools coverage
 isPairedEnd,(Legacy/deprecated annotation) Whether or not is paired-end sequencing (Yes; No). Note that this can be inferred as 'Yes' when runType=pairedEnd; current templates actually use runType to capture this info.,"Yes, No",,FALSE,,ngs,,,,isPairedEnd,DataProperty,Assay,annotationProperty,ngsParameter,,,
 totalReads,"If available, the total number of reads collected from samtools.",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=total_reads,ngs,,,,totalReads,DataProperty,Assay,annotationProperty,ngsParameter,,,
 targetDepth,"The targeted read depth prior to sequencing.",,,FALSE,https://data.humantumoratlas.org/standards/bulkrnaseq#TargetDepth,ngs,,,,targetDepth,DataProperty,Assay,annotationProperty,ngsParameter,,,
+raw counts,The number or amount of something.,"",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C25463,dataType,,"","",Raw_Counts,Class,Data,Data_Class,"","","",""
+Volume,The amount of three dimensional space occupied by an object or the capacity of a space or container.,"",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C25335,dataType,,"","",Volume,Class,Data,Data_Class,"","","",""
+Weight,The vertical force exerted by a mass as a result of gravity.,"",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C25208,dataType,,"","",Weight,Class,Data,Data_Class,"","","",""
+Pharmacokinetic Study,"A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.","",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C49663,dataType,,"","",Pharmacokinetic_Study,Class,Data,Data_Class,"","","",""
+genomicVariants,"Genomic alterations, including single nucleotide polymorphisms, short indels and structural variants. Use more specific term if possible, esp. if data is only of one specific subset.","",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Foperation_3227,dataType,,"","",Genomic_Variants,Class,Data,Data_Class,"","","",""
+AlignedReads,"Aligned reads output from alignment workflows","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads,dataType,,"","",Aligned_Reads,Class,Data,Data_Class,"","","",""
+SomaticVariants,"Called somatic variants","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=simple_somatic_mutation,dataType,,"","",Somatic_Variants,Class,Data,Data_Class,"",,"",""
+AnnotatedSomaticVariants,"Somatic variants annotated with some annotation workflow","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=annotated_somatic_mutation,dataType,,"","",Annotated_Somatic_Variants,Class,Data,Data_Class,"","","",""
+GermlineVariants,"Called germline variants","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=simple_germline_variation,dataType,,"","",Germline_Variants,Class,Data,Data_Class,"","","",""
+AnnotatedGermlineVariants,"Germline variants annotated with some annotation workflow","",assay,FALSE,,dataType,,"","",Annotated_Germline_Variants,Class,Data,Data_Class,"","","",""
+StructuralVariants,"Specifically genomic variants data classified as structural variants, which may be derived from specialized variant calling workflows","",assay,FALSE,,dataType,,"","",Structural_Variants,Class,Data,Data_Class,"","","",""
+behavior process,"The action, reaction, or performance of an organism in response to external or internal stimuli.","",assay,FALSE,hhttps://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=structural_variation,dataType,,"","",Behavior_Process,Class,Data,Data_Class,"","","",""
+metabolomics,"The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism.","",assay,FALSE,http://edamontology.org/topic_3172,dataType,,"","",Metabolomics,Class,Data,Data_Class,"","","",""
+image,Biological or biomedical data that has been rendered into an image.,"",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Fdata_2968,dataType,,"","",Image,Class,Data,Data_Class,"","","",""
+geneExpression,The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data.,"",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Ftopic_0203,dataType,,"","",Gene_Expression,Class,Data,Data_Class,"","","",""
+isoformExpression,Expression of protien isoforms formed from alternative splicings or other post-translational modifications of a single gene through RNA splicing mechanisms.,"",assay,FALSE,https://en.wikipedia.org/wiki/Protein_isoform,dataType,,"","",Isoform_Expression,Class,Data,Data_Class,"","","",""
+proteomics,"Protein and peptide identification, especially in the study of whole proteomes of organisms.","",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Ftopic_0121,dataType,,"","",Proteomics,Class,Data,Data_Class,"","","",""
+kinomics,Kinomics is the study of protein kinases and protein kinase signaling.,"",assay,FALSE,http://www.kinomecore.com/what-is-kinomics/,dataType,,"","",Kinomics,Class,Data,Data_Class,"","","",""
+drugScreen,Information on drug sensitivity and molecular markers of drug response,"",assay,FALSE,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531057/,dataType,,"","",Drug_Screen,Class,Data,Data_Class,"","","",""
+drugCombinationScreen,Information on drug sensitivity of more than one compound,"","",FALSE,https://www.ncbi.nlm.nih.gov/pubmed/29344898,dataType,,"","",Drug_Combination_Screen,Class,Data,Data_Class,"","","",""
+cellularPhysiology,"","",assay,FALSE,"",dataType,,"","",Cellular_Physiology,Class,Data,Data_Class,"","","",""
+chromatinActivity,Chromatin activity that allow access of condensed genomic DNA and potentially control gene expression.,"","",FALSE,https://en.wikipedia.org/wiki/Chromatin_remodeling,dataType,,"","",Chromatin_Activity,Class,Data,Data_Class,"","","",""
+surveyData,A data set that contains the outcome of a survey.,"",assay,FALSE,http://purl.obolibrary.org/obo/OMIABIS_0000060,dataType,,"","",Survey_Data,Class,Data,Data_Class,"","","",""
+network,An interconnected system of things or people.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C61377,dataType,,"","",Network,Class,Data,Data_Class,"","","",""
+clinical,Data obtained through patient examination or treatment.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C15783,dataType,,"","",Clinical_Data,Class,Data,Data_Class,"","","",""
+immunoassay,Laboratory test involving interaction of antigens with specific antibodies.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C16723,dataType,,"","","","",Data,Data_Class,"","","",""
+electrophysiology,Data generated from an electrophysiology assay.,"","",FALSE,http://purl.obolibrary.org/obo/ERO_0000564,dataType,,"","",Electrophysiology,Class,Data,Data_Class,"","","",""
+mask image,"Image used as the mask for an image processing operation, such as subtraction.","","",FALSE,http://dicom.nema.org/resources/ontology/DCM/121321,dataType,,"","",Mask_Image,Class,Data,Data_Class,"","","",""
+curatedData,"Any file derived from or pertaining a manually or programatically curated data resource. Examples include: reference sequences, drug information databases, identifier maps""""","","",FALSE,"","",,"","",Curated_Data,Class,Data,Data_Class,"","","",""
+normalized,A data set that is produced as the output of a normalization data transformation.,"","",FALSE,http://purl.obolibrary.org/obo/OBI_0000451,dataSubtype,,"","",Normalized,Class,Data,Data_Level,"","","",""
+dataMatrix,A file of data containing multiple values for multiple samples.,"","",FALSE,"",dataSubtype,,"","",Data_Matrix,Class,Data,Data_Level,"","","",""
+raw,"A data file produced by an instrument, or one with very little subsequent processing.","","",FALSE,"",dataSubtype,,"","",Raw,Class,Data,Data_Level,"","","",""
+processed,A file of data generated from running one or more bioinformatics methods on a raw file.,"","",FALSE,"",dataSubtype,,"","",Processed,Class,Data,Data_Level,"","","",""
+metadata,"A file of clinical, technical, or other parameters that describe a dataset.","","",FALSE,"",dataSubtype,,"","",Metadata,Class,Data,Data_Level,"","","",""
+representative,"An activity that stands as an equivalent of something or results in an equivalent; typical of, or the same as, others in a larger group of people or things.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C67045,dataSubtype,,"","",Representative,Class,Data,Data_Level,"","","",""
+bash script,Bash Shell Script,"","",FALSE,https://en.wikipedia.org/wiki/Shell_script,fileFormat,,"","",bash_script,Class,Data,File_Format,Open_Format,"","",""
+bedgraph,Holds a tab-delimited chromosome /start /end / datavalue dataset. The bedGraph format allows display of continuous-valued data in track format. This display type is useful for probability scores and transcriptome data,"","",FALSE,http://edamontology.org/format_3583,fileFormat,,"","",bedgraph,Class,Data,File_Format,Open_Format,"","",""
+ai,Adobe Illustrator format,"","",FALSE,http://www.ebi.ac.uk/swo/data/SWO_3000023,fileFormat,,"","",ai,Class,Data,File_Format,Proprietary_Format,"","",""
+idx,"","","",FALSE,"",fileFormat,,"","",idx,Class,Data,File_Format,"","","",""
+idat,Proprietary file format for (raw) BeadArray data used by genomewide profiling platforms from Illumina Inc. This format is output directly from the scanner and stores summary intensities for each probe-type on an array.,"","",FALSE,http://edamontology.org/format_3578,fileFormat,,"","",idat,Class,Data,File_Format,Proprietary_Format,"","",""
+bam,"BAM format, the binary, BGZF-formatted compressed version of SAM format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s)","","",FALSE,http://edamontology.org/format_2572,fileFormat,,"","",bam,Class,Data,File_Format,Open_Format,"","",""
+bai,BAM indexing format,"","",FALSE,http://edamontology.org/format_3327,fileFormat,,"","",bai,Class,Data,File_Format,Open_Format,"","",""
+excel,Microsoft Excel spreadsheet format,"","",FALSE,"",fileFormat,,"","",excel,Class,Data,File_Format,Proprietary_Format,"","",""
+powerpoint,Microsoft Powerpoint slide format,"","",FALSE,"",fileFormat,,"","",powerpoint,Class,Data,File_Format,Proprietary_Format,"","",""
+tif,"Tagged Image File Format, abbreviated TIFF or TIF, is a computer file format for storing raster graphics images","","",FALSE,https://en.wikipedia.org/wiki/TIFF,fileFormat,,"","",tif,Class,Data,File_Format,Preferred_Open_Format,"","",""
+png,PNG is a file format for image compression,"","",FALSE,http://edamontology.org/format_3603,fileFormat,,"","",png,Class,Data,File_Format,Open_Format,"","",""
+doc,Microsoft Word document format,"","",FALSE,"",fileFormat,,"","",doc,Class,Data,File_Format,Proprietary_Format,"","",""
+pdf,Portable Document Format,"","",FALSE,http://edamontology.org/format_3508,fileFormat,,"","",pdf,Class,Data,File_Format,Proprietary_Format,"","",""
+hdf,"Hierarchical Data Format (HDF) is a set of file formats (HDF4, HDF5) designed to store and organize large amounts of data","","",FALSE,https://en.wikipedia.org/wiki/Hierarchical_Data_Format,fileFormat,,"","",hdf,Class,Data,File_Format,Open_Format,"","",""
+fasta,"FASTA format is a text-based format for representing either nucleotide sequences or peptide sequences, in which nucleotides or amino acids are represented using single-letter codes","","",FALSE,https://en.wikipedia.org/wiki/FASTA_format,fileFormat,,"","",fasta,Class,Data,File_Format,Preferred_Open_Format,"","",""
+fastq,FASTQ format is a text-based format for storing both a biological sequence (usually nucleotide sequence) and its corresponding quality scores. Both the sequence letter and quality score are each encoded with a single ASCII character for brevity,"","",FALSE,https://en.wikipedia.org/wiki/FASTQ_format,fileFormat,,"","",fastq,Class,Data,File_Format,Preferred_Open_Format,"","",""
+sam,Sequence Alignment/Map (SAM) format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s),"","",FALSE,http://edamontology.org/format_2573,fileFormat,,"","",sam,Class,Data,File_Format,Open_Format,"","",""
+vcf,"Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)","","",FALSE,http://edamontology.org/format_3016,fileFormat,,"","",vcf,Class,Data,File_Format,Open_Format,"","",""
+bcf,"BCF, the binary version of Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)","","",FALSE,http://edamontology.org/format_3016,fileFormat,,"","",bcf,Class,Data,File_Format,Open_Format,"","",""
+maf,"Multiple Alignment Format (MAF) supporting alignments of whole genomes with rearrangements, directions, multiple pieces to the alignment, and so forth","","",FALSE,http://edamontology.org/format_3008,fileFormat,,"","",maf,Class,Data,File_Format,Open_Format,"","",""
+bed,"Browser Extensible Data (BED) format of sequence annotation track, typically to be displayed in a genome browser","","",FALSE,http://edamontology.org/format_3003,fileFormat,,"","",bed,Class,Data,File_Format,Open_Format,"","",""
+chp,CHP file contains probe set analysis results generated from Affymetrix software,"","",FALSE,"",fileFormat,,"","",chp,Class,Data,File_Format,Proprietary_Format,"","",""
+cel,Format of Affymetrix data file of information about (raw) expression levels of the individual probes,"","",FALSE,http://edamontology.org/format_1638,fileFormat,,"","",cel,Class,Data,File_Format,Proprietary_Format,"","",""
+sif,SIF (simple interaction file) Format - a network/pathway format used for instance in cytoscape,"","",FALSE,http://edamontology.org/format_3619,fileFormat,,"","",sif,Class,Data,File_Format,"","","",""
+tsv,Tabular data represented as tab-separated values in a text file,"","",FALSE,http://edamontology.org/format_3475,fileFormat,,"","",tsv,Class,Data,File_Format,Preferred_Open_Format,"","",""
+csv,Tabular data represented as comma-separated values in a text file,"","",FALSE,http://edamontology.org/format_3752,fileFormat,,"","",csv,Class,Data,File_Format,Preferred_Open_Format,"","",""
+txt,Textual format,"","",FALSE,http://edamontology.org/format_2330,fileFormat,,"","",txt,Class,Data,File_Format,Preferred_Open_Format,"","",""
+plink,Any Plink file format (MAP/PED/BED/BIM/FAM),"","",FALSE,https://www.cog-genomics.org/plink2/formats,fileFormat,,"","",plink,Class,Data,File_Format,Open_Format,"","",""
+bigwig,bigWig format for large sequence annotation tracks that consist of a value for each sequence position,"","",FALSE,http://edamontology.org/format_3006,fileFormat,,"","",bigwig,Class,Data,File_Format,Open_Format,"","",""
+wiggle,Wiggle format (WIG) of a sequence annotation track that consists of a value for each sequence position,"","",FALSE,http://edamontology.org/format_3005,fileFormat,,"","",wiggle,Class,Data,File_Format,Open_Format,"","",""
+gct,"Tab-delimited text files of GenePattern that contain a column for each sample, a row for each gene, and an expression value for each gene in each sample","","",FALSE,http://edamontology.org/format_3709,fileFormat,,"","",gct,Class,Data,File_Format,"","","",""
+bgzip,Blocked GNU Zip format,"","",FALSE,http://edamontology.org/format_3615,fileFormat,,"","",bgzip,Class,Data,File_Format,Open_Format,"","",""
+zip,zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification,"","",FALSE,http://purl.obolibrary.org/obo/OBI_0000325,fileFormat,,"","",zip,Class,Data,File_Format,Open_Format,"","",""
+seg,SEG file (segmented data; .seg or .cbs) is a tab-delimited text file that lists loci and associated numeric values,"","",FALSE,https://software.broadinstitute.org/software/igv/SEG,fileFormat,,"","",seg,Class,Data,File_Format,Open_Format,"","",""
+html,HTML format,"","",FALSE,http://edamontology.org/format_2331,fileFormat,,"","",html,Class,Data,File_Format,"","","",""
+mov,A video file format with the .mov extension,"","",FALSE,Sage Bioenetworks,fileFormat,,"","",mov,Class,Data,File_Format,"","","",""
+hyperlink,"A reference (link) from some point in one hypertext document to another document, another place in the same document, or a website.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C47919,fileFormat,,"","",hyperlink,Class,Data,File_Format,"","","",""
+svs,"A single-file pyramidal tiled TIFF, with non-standard metadata and compression.","","",FALSE,https://openslide.org/formats/aperio/,fileFormat,,"","",svs,Class,Data,File_Format,"","","",""
+md,Markdown (MD) is a lightweight markup language with plain text formatting syntax,"","",FALSE,https://en.wikipedia.org/wiki/Markdown,fileFormat,,"","",md,Class,Data,File_Format,"","","",""
+flagstat,Output of samtools flagstat tool,"","",FALSE,"",fileFormat,,"","",flagstat,Class,Data,File_Format,"","","",""
+gtf,Gene transfer format (GTF) is a file format used to hold information about gene structure,"","",FALSE,https://en.wikipedia.org/wiki/Gene_transfer_format,fileFormat,,"","",gtf,Class,Data,File_Format,"","","",""
+raw,Proprietary file format for mass spectrometry data from Thermo Scientific,"","",FALSE,http://edamontology.org/format_3712,fileFormat,,"","",raw,Class,Data,File_Format,"","","",""
+msf,Proprietary mass-spectrometry format of Thermo Scientific's ProteomeDiscoverer software,"","",FALSE,http://edamontology.org/format_3702,fileFormat,,"","",msf,Class,Data,File_Format,"","","",""
+rmd,markdown document specific to r analyses,"","",FALSE,http://rmarkdown.rstudio.com/developer_document_templates.html,fileFormat,,"","",rmd,Class,Data,File_Format,"","","",""
+bed narrowPeak,"This format is used to provide called peaks of signal enrichment based on pooled, normalized (interpreted) data. It is a BED6+4 format.","","",FALSE,http://genome.ucsc.edu/FAQ/FAQformat.html#format12,fileFormat,,"","",bed_narrowPeak,Class,Data,File_Format,"","","",""
+bed broadPeak,"This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data. It is a BED 6+3 format.","","",FALSE,http://genome.ucsc.edu/FAQ/FAQformat.html#format13,fileFormat,,"","",bed_broadPeak,Class,Data,File_Format,"","","",""
+bed gappedPeak,"This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data where the regions may be spliced or incorporate gaps in the genomic sequence. It is a BED12+3 format.","","",FALSE,http://genome.ucsc.edu/FAQ/FAQformat.html#format14,fileFormat,,"","",bed_gappedPeak,Class,Data,File_Format,"","","",""
+avi,AVI files can contain both audio and video data in a file container that allows synchronous audio-with-video playback.,"","",FALSE,https://en.wikipedia.org/wiki/Audio_Video_Interleave,fileFormat,,"","",avi,Class,Data,File_Format,"","","",""
+pzfx,"A PZFX file is a Prism project created by GraphPad Prism, a scientific application used to analyze and graph data. It contains project data including graphs and layouts, notes, and tables.","","",FALSE,https://fileinfo.com/extension/pzfx,fileFormat,,"","",pzfx,Class,Data,File_Format,"","","",""
+fig,"Line drawing saved in the Xfig format; stored as a vector image that may include lines, shapes, arcs, splines, arrows, and text objects; may also include images, colors, and patterns.","","",FALSE,https://fileinfo.com/extension/fig,fileFormat,,"","",fig,Class,Data,File_Format,"","","",""
+xml,eXtensible Markup Language (XML) format.,"","",FALSE,http://edamontology.org/format_2332,fileFormat,,"","",xml,Class,Data,File_Format,Preferred_Open_Format,"","",""
+tar,tape archive,"","",FALSE,https://en.wikipedia.org/wiki/Tar_(computing),fileFormat,,"","",tar,Class,Data,File_Format,"","","",""
+R script,R script with expected extension “.R”.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",R_script,Class,Data,File_Format,"","","",""
+abf,The Axon Binary File format (ABF) was created for the storage of binary experimental data.,"","",FALSE,https://mdc.custhelp.com/euf/assets/content/ABFHelp.pdf,fileFormat,,"","",abf,Class,Data,File_Format,"","","",""
+bpm,A beaded pool manifest. Describe the SNP or probe content on a BeadChip or in an assay pool.,"","",FALSE,https://support.illumina.com/datafiles.html,fileFormat,,"","",bpm,Class,Data,File_Format,"","","",""
+dat,Format of Affymetrix data file of raw image data.,"","",FALSE,http://edamontology.org/format_1637,fileFormat,,"","",dat,Class,Data,File_Format,"","","",""
+jpg,Joint Picture Group file format for lossy graphics file.,"","",FALSE,http://edamontology.org/format_3579,fileFormat,,"","",jpg,Class,Data,File_Format,"","","",""
+locs,Illumina iScan bead location file.,"","",FALSE,https://support.illumina.com/content/dam/illumina-support/documents/documentation/system_documentation/iscan/iscan-system-guide-11313539-01.pdf,fileFormat,,"","",locs,Class,Data,File_Format,"","","",""
+Sentrix descriptor file,A BeadScan specific file needed to perform scan setting checks for different array formats and assay type.,"","",FALSE,https://support.illumina.com/content/dam/illumina-support/documents/myillumina/dd0aff11-2664-481b-a8ce-26831a907cae/beadscan_3.0_software_addendum.pdf,fileFormat,,"","",Sentrix_descriptor_file,Class,Data,File_Format,"","","",""
+Python script,Python script with expected extension “.py”.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",Python_script,Class,Data,File_Format,"","","",""
+MATLAB script,A MATLAB script file with expected extension “.m”. Note that files with a “.mat” extension contains MATLAB formatted data.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",MATLAB_script,Class,Data,File_Format,"","","",""
+MATLAB data,A MATLAB formatted data file with expected extension “.mat”.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",MATLAB_data,Class,Data,File_Format,"","","",""
+sav,"The SPSS Statistics File Format is a proprietary binary format, developed and maintained as the native format for the SPSS statistical software application.","","",FALSE,https://www.loc.gov/preservation/digital/formats/fdd/fdd000469.shtml,fileFormat,,"","",sav,Class,Data,File_Format,"","","",""
+gzip,GZipped format,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C80220,fileFormat,,"","",gzip,Class,Data,File_Format,"","","",""
+sdf,SDF is one of a family of chemical-data file formats developed by MDL Information Systems; it is intended especially for structural information.,"","",FALSE,http://edamontology.org/format_3814,fileFormat,,"","",sdf,Class,Data,File_Format,"","","",""
+RData,"The RData format (usually with extension .rdata or .rda) is a format designed for use with R, a system for statistical computation and related graphics, for storing a complete R workspace or selected 'objects' from a workspace in a form that can be loaded back by R.","","",FALSE,https://www.loc.gov/preservation/digital/formats/fdd/fdd000470.shtml,fileFormat,,"","",RData,Class,Data,File_Format,"","","",""
+hic,Hi-C contact matrix file,"","",FALSE,https://github.com/theaidenlab/juicer/wiki/Data,fileFormat,,"","",hic,Class,Data,File_Format,"","","",""
+ab1,TAB1 binary format of raw DNA sequence reads (output of Applied Biosystems' sequencing analysis software). Contains an electropherogram and the DNA base sequence.,"","",FALSE,http://edamontology.org/format_3000,fileFormat,,"","",ab1,Class,Data,File_Format,"","","",""
+7z,"A compressed archive file format that supports several different data compression, encryption and pre-processing filters.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C80224,fileFormat,,"","",7z,Class,Data,File_Format,"","","",""
+gff3,Generic Feature Format version 3 (GFF3) of sequence features.,"","",FALSE,http://edamontology.org/format_1975,fileFormat,,"","",gff3,Class,Data,File_Format,"","","",""
+json,"JavaScript Object Notation format; a lightweight, text-based format to represent tree-structured data using key-value pairs.","","",FALSE,http://edamontology.org/format_3464,fileFormat,,"","",json,Class,Data,File_Format,"","","",""
+sqlite,Data format used by the SQLite database.,"","",FALSE,http://edamontology.org/format_3621,fileFormat,,"","",sqlite,Class,Data,File_Format,"","","",""
+svg,Scalable Vector Graphics (SVG) is an XML-based vector image format for two-dimensional graphics with support for interactivity and animation.,"","",FALSE,http://edamontology.org/format_3604,fileFormat,,"","",svg,Class,Data,File_Format,"","","",""
+sra,SRA archive format (SRA) is the archive format used for input to the NCBI Sequence Read Archive.,"","",FALSE,http://edamontology.org/format_3698,fileFormat,,"","",sra,Class,Data,File_Format,"","","",""
+recal,.recal file from GATK VQSR,"","",FALSE,https://software.broadinstitute.org/gatk/documentation/tooldocs/3.8-0/org_broadinstitute_gatk_tools_walkers_variantrecalibration_VariantRecalibrator.php#--recal_file,fileFormat,,"","",recal,Class,Data,File_Format,"","","",""
+tranches,.tranches file from GATK VQSR,"","",FALSE,https://software.broadinstitute.org/gatk/documentation/tooldocs/3.8-0/org_broadinstitute_gatk_tools_walkers_variantrecalibration_VariantRecalibrator.php#--tranches_file,fileFormat,,"","",tranches,Class,Data,File_Format,"","","",""
+mtx,Matrix Market Exchange Format,"","",FALSE,https://math.nist.gov/MatrixMarket/formats.html#MMformat,fileFormat,,"","",mtx,Class,Data,File_Format,"","","",""
+tagAlign,Tag Alignment provides genomic mapping of short sequence tags.,"","",FALSE,https://genome.ucsc.edu/FAQ/FAQformat.html#format15,fileFormat,,"","",tagAlign,Class,Data,File_Format,"","","",""
+dup,output of the Picard MarkDuplicates tool.,"","",FALSE,https://software.broadinstitute.org/gatk/documentation/tooldocs/4.0.4.0/picard_sam_markduplicates_MarkDuplicates.php,fileFormat,,"","",dup,Class,Data,File_Format,"","","",""
+DICOM,"A comprehensive set of standards for communications between medical imaging devices, including handling, storing and transmitting information in medical imaging. It includes a file format definition and a network communication protocol.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C49059,fileFormat,,"","",DICOM,Class,Data,File_Format,"","","",""
+czi,"microscopy imaging file format that saves multidimensional images such as time lapse, Z-stacks, multiposition experiments and virtual slides, combined with relevant meta information","","",FALSE,https://www.zeiss.com/microscopy/int/products/microscope-software/zen/czi.html,fileFormat,,"","",czi,Class,Data,File_Format,"","","",""
+mzML,"mzML format for raw spectrometer output data, standardised by HUPO PSI MSS.","","",FALSE,http://edamontology.org/format_3244,fileFormat,,"","",mzML,Class,Data,File_Format,Preferred_Open_Format,"","",""
+SPAR,Phillips MRS Header File,"","",FALSE,https://github.com/chenkonturek/MRS_MRI_libs,fileFormat,,"","",SPAR,Class,Data,File_Format,"","","",""
+SDAT,Phillips MRS Data File,"","",FALSE,https://github.com/chenkonturek/MRS_MRI_libs,fileFormat,,"","",SDAT,Class,Data,File_Format,"","","",""
+nii,"NIfTI-1 can store image data from any modality such as PET, MRI, CT, EEG that produces regularly sampled 1-5D rasters.","","",FALSE,https://nifti.nimh.nih.gov/nifti-1/documentation/faq,fileFormat,,"","",nii,Class,Data,File_Format,"","","",""
+PAR,This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).,"","",FALSE,https://nipy.org/nibabel/reference/nibabel.parrec.html,fileFormat,,"","",PAR,Class,Data,File_Format,"","","",""
+REC,This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).,"","",FALSE,https://nipy.org/nibabel/reference/nibabel.parrec.html,fileFormat,,"","",REC,Class,Data,File_Format,"","","",""
+hdr,"MRI Header file, as in the NIFTI-1 Analyze 7.5 format","","",FALSE,https://nifti.nimh.nih.gov/pub/dist/src/niftilib/nifti1.h,fileFormat,,"","",hdr,Class,Data,File_Format,"","","",""
+img,"MRI Data file, as in the NIFTI-1 Analyze 7.5 format","","",FALSE,https://nifti.nimh.nih.gov/pub/dist/src/niftilib/nifti1.h,fileFormat,,"","",img,Class,Data,File_Format,"","","",""
+sf,"Salmon’s main output is its quantification file. This file is a plain-text, tab-separated file with a single header line (which names all of the columns).","","",FALSE,https://salmon.readthedocs.io/en/latest/file_formats.html,fileFormat,,"","",sf,Class,Data,File_Format,"","","",""
+tom,"The .tom format is a specialized 3D image export format from the Vectra medical imaging systems that can optionally preserve trimmings and/or landmarks.","","",FALSE,http://canfieldupgrade.com/assets/media/VECTRA-M3-User-Guide.pdf,fileFormat,,"","",tom,Class,Data,File_Format,"","","",""
+gene symbol,A unique gene name approved by an organism specific nomenclature committee.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C43568,curatedDataType,,,,Gene_Symbol,Class,Data,Metadata,,,,
+clinical data,Data obtained through patient examination or treatment.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C15783,curatedDataType,,,,Clinical_Curated_Data,Class,Data,Metadata,,,,
+gene function,A term that expresses the function of a gene product.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C48933,curatedDataType,,,,Gene_Function,Class,Data,Metadata,,,,
+chemical descriptor,"A chemical descriptor is a data item (quantity or value) about a chemical entity that conforms to a specification for how it is calculated, measured or recorded.",,,FALSE,http://semanticscience.org/resource/CHEMINF_000123,curatedDataType,,,,Chemical_Descriptor,Class,Data,Metadata,,,,
+individual,Metadata describing properties of individuals (human or animal) represented in the study.,,,FALSE,Sage Bionetworks,metadataType,,,,Individual_Annotation,Class,Data,Metadata,,,,
+biospecimen,Metadata describing properties of specimens collected and/or analyzed in the study.,,,FALSE,Sage Bionetworks,metadataType,,,,Biospecimen_Annotation,Class,Data,Metadata,,,,
+assay,Metadata describing properties of an assay conducted in the study.,,,FALSE,Sage Bionetworks,metadataType,,,,Assay_Annotation,Class,Data,Metadata,,,,
+data dictionary,Metadata describing terms or variables that appear in another file.,,,FALSE,Sage Bionetworks,metadataType,,,,Data_Dictionary,Class,Data,Metadata,,,,
+manifest,Metadata describing a list of files and the annotations terms associated with them.,,,FALSE,Sage Bionetworks,metadataType,,,,Manifest,Class,Data,Metadata,,,,
+protocol,"A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",,,FALSE,http://purl.obolibrary.org/obo/OBI_0000272,metadataType,,,,Protocol,Class,Data,Metadata,,,,
+GRCh38,Genome Reference Consortium Human Build 38,,,FALSE,https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.26,referenceSet,,,,GRCh38,Class,Data,Metadata,,,,
+GRCh37,Genome Reference Consortium Human Build 37,,,FALSE,https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.13/,referenceSet,,,,GRCh37,Class,Data,Metadata,,,,
+MMUL1.0,Ensembl preliminary assembly Macaca mulatta,,,FALSE,https://jul2016.archive.ensembl.org/Macaca_mulatta/Info/Index,referenceSet,,,,MMUL1.0,Class,Data,Metadata,,,,
+HRC,Human haplotype reference panel,,,FALSE,http://www.haplotype-reference-consortium.org,referenceSet,,,,HRC,Class,Data,Metadata,,,,
+experimentalData,"Any file derived from or pertaining to a scientific experiment. experimentalData annotations should be applied, possibly disease-related",,,FALSE,Sage Bionetworks,resourceType,,,,Experimental_Data,Class,Data,Metadata,Resource,,,
+result,"Any file that reports data results. Examples include figures, presentations, analysis, etc.",,,FALSE,Sage Bionetworks,resourceType,,,,Result,Class,Data,Metadata,Resource,,,
+tool,"Any file or link that represents a tool, model, or algorithm; the tool annotations could be applied",,,FALSE,Sage Bionetworks,resourceType,,,,Tool,Class,Data,Metadata,Resource,,,
+workflow report,"Workflow-generated reports of analysis of primary data, usually created programmatically at completion of workflow step.",,,FALSE,,resourceType,,,,Workflow_Report,Class,Data,Metadata,Report,,,
+report,"a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).",,,FALSE,http://purl.obolibrary.org/obo/IAO_0000088,resourceType,,,,Report,Class,Data,Metadata,Resource,,,
+metadata,Data about data; information that describes another set of data.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C52095,resourceType,,,,metadata,Class,Data,Metadata,Resource,,,
+protocol,"A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",,,FALSE,http://purl.obolibrary.org/obo/OBI_0000272,resourceType,,,,Protocol,Class,Data,Metadata,Resource,,,
+curatedDataType,The type of information being curated.,"reference sequence, gene symbol, clinical data, gene function, chemical descriptor",,TRUE,,curatedData,,,,curatedDataType,Property,Data,annotationProperty,,,,
+referenceSet,"A set of references (e.g., canonical assembled contigs) which defines a common coordinate space for comparing reference-aligned experimental data.","GRCh38, GRCh37, MMUL1.0, HRC",,TRUE,,curatedData,,,,referenceSet,Property,Data,annotationProperty,,,,
+reference sequence,Syntactic sequences that has a role as reference of an annotation.,,,FALSE,http://rdf.biosemantics.org/ontologies/rsa#ReferenceSequence,curatedDataType,,,,referenceSequence,Property,Data,annotationProperty,,,,
+dataSubtype,"Further qualification of dataType, which may be used to indicate the state of processing of the data, aggregation of the data, or presence of metadata.","normalized, dataMatrix, raw, processed, metadata, representative",,TRUE,,experimentalData,,,,dataSubtype,Property,Data,annotationProperty,,Data_Level,one,
+metadataType,"For files of dataSubtype: metadata, a description of the type of metadata in the file.","individual, biospecimen, assay, data dictionary, manifest, protocol",,FALSE,,experimentalData,,,,metadataType,Property,Data,annotationProperty,,,,
+dataType,"A type of experimental, clinical, or other data. This typically refers to a high-level data type that can be related to an assay type. For example, a file of dataType `genomicVariants` might have an assay value of `whole genome sequencing`.","Volume, Weight, Pharmacokinetic Study, genomicVariants,behavior process, metabolomics, image, geneExpression, isoformExpression, proteomics, kinomics, drugScreen, drugCombinationScreen, cellularPhysiology, chromatinActivity, surveyData, network, clinical, immunoassay, electrophysiology, raw counts, mask image,AlignedReads,SomaticVariants,AnnotatedSomaticVariants,StructuralVariants,GermlineVariants,AnnotatedGermlineVariants",dataSubtype,TRUE,,experimentalData,,,,dataType,Property,Data,annotationProperty,,Data,one,
+expressionUnit,"Measure used for transcript expression quantification","TPM,RPKM,FPKM,Counts,Other",,TRUE,,experimentalData,,,,expressionUnit,DataProperty,Data,annotationProperty,,,,
+failedQC,Whether the sample or data failed QC checks (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,failedQC,DataProperty,Data,annotationProperty,,,,
+Filename,The name of the file.,,"entityId,fileFormat",TRUE,Sage Bionetworks,NF,,,,fileName,Class,Data,annotationProperty,fileName,,one,Automatically filled when using the curator app.
+programmingLanguage,A computer programming language,"Python, R, MATLAB, Java, C, C++, C#, Javascript, bash",,FALSE,Sage Bionetworks,,,,,programmingLanguage,Property,Data,annotationProperty,ngsParameter,,,
+runtimePlatform,"Runtime platform or script interpreter dependencies (e.g. Java v1, Python 2.3).",,,FALSE,Sage Bionetworks,,,,,runtimePlatform,Property,Data,annotationProperty,ngsParameter,,,
+documentation,URL to any documentation describing the resource and its use.,,,FALSE,Sage Bionetworks,,,,,documentation,Property,Data,annotationProperty,ngsParameter,,,
+resourceType,The type of resource being stored and annotated,"experimentalData, curatedData, result, tool, report, metadata, protocol, workflow report",,TRUE,,sageCommunity,,,,resourceType,Property,Data,annotationProperty,,Resource,,
+fileFormat,"Defined format of the data file, typically corresponding to extension, but sometimes indicating more general group of files produced by the same tool or software","bash script,bedgraph,ai,idx,idat,bam,bai,excel,powerpoint,tif,png,doc,pdf,hdf,fasta,fastq,sam,vcf,bcf,maf,bed,chp,cel,sif,tsv,csv,txt,plink,bigwig,wiggle,gct,bgzip,zip,seg,html,mov,hyperlink,svs,md,flagstat,gtf,raw,msf,rmd,bed narrowPeak,bed broadPeak,bed gappedPeak,avi,pzfx,fig,xml,tar,R script,abf,bpm,dat,jpg,locs,Sentrix descriptor file,Python script,sav,gzip,sdf,RData,hic,ab1,7z,gff3,json,sqlite,svg,sra,recal,tranches,mtx,tagAlign,dup,DICOM,czi,mzML,SPAR,SDAT,nii,PAR,REC,hdr,img,sf,MATLAB script, MATLAB data,tom",,TRUE,,sageCommunity,,,,fileFormat,Property,Data,annotationProperty,,File_Format,one,
+progressReportNumber,"Indicates milestone the  data is associated with. Currently only required for projects funded by NTAP, GFF, and NFRI. For GFF studies, this is the ‘progress report’ timeline. Example: if submitting data for the 6-month milestone report for NTAP, progressReportNumber=1.  Also if submitting data associated with first milestone, progressReportNumber =1","1, 2, 3, 4, 5, 6, 7, 8, 9, 10, Not Applicable",,FALSE,,template,,,,progressReportNumber,DataProperty,Data,annotationProperty,,,one,
+comments,Brief free-text comments that may also be important to understanding the resource.,,,FALSE,Sage Bionetworks,experimentalData,,,,comments,DataProperty,Data,annotationProperty,,,many,
+Resource_id,A UUID for a Resource from the NF Research Tools Database,,,FALSE,Sage Bionetworks,dccProperty,,,,Resource_id,Property,Data,annotationProperty,dccProperty,,,
+initiative,"Refers to a funding initiative. This annotation is usually handled by the DCC or funder, not the researcher. ",,,FALSE,Sage Bionetworks,dccProperty,,,,initiative,Property,Data,annotationProperty,dccProperty,,,
+fundingAgency,Refers to the funding organization for the generated resource. This annotation is handled by the DCC.,,,FALSE,Sage Bionetworks,dccProperty,,,,fundingAgency,Property,Data,annotationProperty,dccProperty,,,
+createdOn,Refers to when the resource was created on the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,createdOn,Property,Data,annotationProperty,synapseProperty,,,
+createdBy,Refers to the user who created the resource on the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,createdBy,Property,Data,annotationProperty,synapseProperty,,,
+modifiedBy,Refers to a user who last modified the resource on the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,modifiedBy,Property,Data,annotationProperty,synapseProperty,,,
+id,The entity id for the resource automatically assigned by the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,id,Property,Data,annotationProperty,synapseProperty,,,
+etag,Synapse employs an Optimistic Concurrency Control (OCC) scheme to handle concurrent updates. The E-Tag changes every time an entity is updated it is used to detect when a client's current representation of an entity is out-of-date.,,,FALSE,Sage Bionetworks,synapseProperty,,,,etag,Property,Data,annotationProperty,synapseProperty,,,
+parentId,"The id of the parent resource, i.e. the parent folder on the platform. ",,,FALSE,Sage Bionetworks,synapseProperty,,,,parentId,Property,Data,annotationProperty,synapseProperty,,,
+benefactorId,The id of the resource from which access control is inherited.,,,FALSE,Sage Bionetworks,synapseProperty,,,,benefactorId,Property,Data,annotationProperty,synapseProperty,,,
+currentVersion,(Versionable entities only) The current version number of the resource.,,,FALSE,Sage Bionetworks,synapseProperty,,,,currentVersion,Property,Data,annotationProperty,synapseProperty,,,
+dataFileHandleId,(Files only) Refers to the id of the file.,,,FALSE,Sage Bionetworks,synapseProperty,,,,dataFileHandleId,Property,Data,annotationProperty,synapseProperty,,,
+contentSize,(Files only) File size calculated by the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,contentSize,Property,Data,annotationProperty,synapseProperty,,,
+type,"Refers to the type of the resource on the platform, e.g. “file”.",,,FALSE,Sage Bionetworks,synapseProperty,,,,type,Property,Data,annotationProperty,synapseProperty,,,
+concreteType,Refers to the class model the data platform uses for representing the resource. This is a low-level field set by the platform and is not a user annotation.,,,FALSE,Sage Bionetworks,synapseProperty,,,,concreteType,Property,Data,annotationProperty,synapseProperty,,,
+author,"The author of the resource; preferably use an ORCID ID, GitHub profile link, etc., if available and a text name if not.",,,FALSE,Sage Bionetworks,,,,,,Property,Data,annotationProperty,,,,
+license,Link to a license or name of license applicable for the resource.,,,,,,,,,,,,,,,,
+allograft,"Tissues, cells, or organs transplanted between genetically different individuals of the same species","","",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064591,transplantationType,,"","",Allograft,Class,Experiment,Method,"","","",""
+xenograft,"Tissues, cells or organs transplanted between animals of different species","","transplantationRecipientSpecies,transplantationRecipientTissue",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064593,transplantationType,,"","",Xenograft,Class,Experiment,Method,"","","",""
+autograft,"Transplant comprised of an individual's own tissue, transferred from one part of the body to another.","","transplantationRecipientSpecies,transplantationRecipientTissue",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064592,transplantationType,,"","",Autograft,Class,Experiment,Method,"","","",""
+isograft,"Tissues, cells or organs transplanted between genetically identical individuals","","",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064596,transplantationType,,"","",Isograft,Class,Experiment,Method,"","","",""
+seconds,"","","",FALSE,"",timePointUnit,,"","",seconds,Class,Experiment,Unit,Time_Unit,"","",""
+minutes,"","","",FALSE,"",timePointUnit,,"","",minutes,Class,Experiment,Unit,Time_Unit,"","",""
+hours,"","","",FALSE,"",timePointUnit,,"","",hours,Class,Experiment,Unit,Time_Unit,"","",""
+days,"","","",FALSE,"",timePointUnit,,"","",days,Class,Experiment,Unit,Time_Unit,"","",""
+weeks,"","","",FALSE,"",timePointUnit,,"","",weeks,Class,Experiment,Unit,Time_Unit,"","",""
+months,"","","",FALSE,"",timePointUnit,,"","",months,Class,Experiment,Unit,Time_Unit,"","",""
+quarters,Time point unit referring to quarters in a year.,"","",FALSE,"","",,"","",quarters,Class,Experiment,Unit,Time_Unit,"","",""
+transplantationType,"Type of transplantation involved in the experiment, derived from MESH","allograft, xenograft, autograft, isograft","transplantationRecipientSpecies,transplantationRecipientTissue",FALSE,Sage Bionetworks,cancer,,,,transplantationType,Property,Experiment,annotationProperty,transplantationCharacteristic,,,
+transplantationRecipientSpecies,Species into which donor tissue was grown,"Human, Mouse",,FALSE,Sage Bionetworks,cancer,,,,transplantationRecipientSpecies,Property,Experiment,annotationProperty,transplantationCharacteristic,,,
+timePointUnit,For timed experiments this represents the unit of time measured,"seconds, minutes, hours, days, weeks, months, quarters",,FALSE,Sage Bionetworks,cancer,,,,timePointUnit,Property,Experiment,annotationProperty,,Time_Unit,,
+experimentalCondition,A free-text description of the experimental condition (e.g. 5 mM doxorubicin).,,,FALSE,Sage Bionetworks,sageCommunity,,,,experimentalCondition,Property,Experiment,annotationProperty,experimentProperty,,,
+experimentalTimepoint,The numeric value indicating the time elapsed from the beginning of the experiment at which the specimen was collected. Use in tandem with timePointUnit,,timePointUnit,FALSE,Sage Bionetworks,sageCommunity,,,,experimentalTimepoint,Property,Experiment,annotationProperty,experimentProperty,,,
+transplantationRecipientTissue,Tissue into which a xenograph sample is transplanted,,,FALSE,Sage Bionetworks,sageCommunity,,,,transplantationRecipientTissue,Property,Experiment,annotationProperty,,,,
+experimentId,"When applicable, an optional identifier that can be used to distinguish or group the experiments that generated the data; also can be used to denote internal batch reference if needed.",,,FALSE,Sage Bionetworks,sageCommunity,,,,experimentId,Property,Experiment,annotationProperty,experimentProperty,,,
+compoundName,"Common name for a compound, e.g. “Selumetinib” (https://pubchem.ncbi.nlm.nih.gov/compound/10127622)",,InChIKey,FALSE,Sage Bionetworks,sageCommunity,,,,compoundName,Property,Experiment,annotationProperty,experimentProperty,,,
+compoundDose,A dose quantity for the treatment compound. To be used with compoundDoseUnit.,,compoundDoseUnit,FALSE,Sage Bionetworks,sageCommunity,,,,compoundDose,Property,Experiment,annotationProperty,experimentProperty,,,
+compoundDoseUnit,A unit associated with the value(s) in compoundDose.,,,FALSE,Sage Bionetworks,sageCommunity,,,,compoundDoseUnit,Property,Experiment,annotationProperty,experimentProperty,,,
+InChIKey,"A unique hash key for a compound, e.g. for “Selumetinib”, the key is CYOHGALHFOKKQC-UHFFFAOYSA-N (https://pubchem.ncbi.nlm.nih.gov/compound/10127622#section=InChI-Key). This is a more reliable identifier than the compound name and should be used if available.",,,FALSE,Sage Bionetworks,sageCommunity,,,,InChIKey,Property,Experiment,annotationProperty,experimentProperty,,,
+genePerturbationType,Specific way in which a single gene was perturbed in a sample,"overexpression, knockdown, knockout, non-targeting control, Not Applicable",,FALSE,Sage Bionetworks,cancer,,,,genePerturbationType,Property,Experiment,annotationProperty,,Gene_Perturbation,,
+genePerturbationTechnology,Technology used to perform gene perturbation,"RNAi, CRISPR, CRE Recombinase",,FALSE,Sage Bionetworks,cancer,,,,genePerturbationTechnology,Property,Experiment,annotationProperty,,Gene_Perturbation_Technology,,
+genePerturbed,The HUGO gene symbol for the gene that is perturbed.,,"genePerturbationType,genePerturbationTechnology",FALSE,Sage Bionetworks,sageCommunity,,,,genePerturbed,Property,Assay,annotationProperty,experimentProperty,,,
+JAX,The Jackson Laboratory,"","",FALSE,https://www.jax.org,individualIdSource,,"","",JAX,Class,Other,Organization,"","","",""
+sageCommunity,"","","",FALSE,"","",,"","","",Class,Other,Organization,"","","",""
+workflow,"Name and version of the workflow used to generate/analyze the data",,workflowLink,FALSE,,,,,,workflow,Property,Processing,annotationProperty,,,,
+workflowLink,"Workflow URL reference",,,FALSE,,,,,,workflowLink,Property,Processing,annotationProperty,,,,
+genomicReference,"Version of genome reference used for alignment in processing workflow",,,FALSE,,,,,,genomicReference,Property,Processing,annotationProperty,,,,
+averageInsertSize,"Average insert size as reported by samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=average_insert_size,,,,,averageInsertSize,Property,Processing,annotationProperty,,,,
+averageReadLength,"Average read length collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=average_read_length,,,,,averageReadLength,Property,Processing,annotationProperty,,,,
+averageBaseQuality,"Average base quality collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=average_base_quality,,,,,averageBaseQuality,Property,Processing,annotationProperty,,,,
+pairsOnDifferentChr,"Pairs on different chromosomes collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=pairs_on_diff_chr,,,,,pairsOnDifferentChr,Property,Processing,annotationProperty,,,,
+readsDuplicatedPercent,"Percent of duplicated reads collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_reads_duplicated,,,,,readsDuplicatedPercent,Property,Processing,annotationProperty,,,,
+readsMappedPercent,"Percent of mapped reads collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_reads_mapped,,,,,readsMappedPercent,Property,Processing,annotationProperty,,,,
+meanCoverage,"Mean coverage for whole genome sequencing, or mean target coverage for whole exome and targeted sequencing, collected from Picard Tools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=mean_coverage,,,,,meanCoverage,Property,Processing,annotationProperty,,,,
+proportionCoverage10x,"Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 10X or greater coverage from Picard Tools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_coverage_10x,,,,,proportionCoverage10x,Property,Processing,annotationProperty,,,,
+proportionCoverage30x,"Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 30X or greater coverage from Picard Tools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_coverage_30x,,,,,proportionCoverage30x,Property,Processing,annotationProperty,,,,
 head,The head is the anterior-most division of the body.,"","",FALSE,http://purl.obolibrary.org/obo/UBERON_0000033,bodyPart,,"","",Head,Class,Biosample,Body_Part,Body_Part,"","",""
 lymph node,A bean-shaped organ surrounded by a connective tissue capsule.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C12745,organ,,"","",Lymph_Node,Class,Biosample,Body_Part,Organ,"","",""
 kidney,One of the two bean-shaped organs located on each side of the spine in the retroperitoneum.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C12415,organ,,"","",Kidney,Class,Biosample,Body_Part,Organ,"","",""
@@ -313,6 +535,8 @@ Unknown,unknown,"","",FALSE,Sage Bionetworks,nf1Genotype,,"","",NF1_Unknown_Geno
 +/-,Heterozygous deletion or mutation,"","",FALSE,Sage Bionetworks,nf2Genotype,,"","",NF2_Heterozygous_Deletion_Mutation,Class,Biosample,Genotype,NF2_Genotype,"","",""
 +/+,Homozygous wild type,"","",FALSE,Sage Bionetworks,nf2Genotype,,"","",NF2_Wildtype,Class,Biosample,Genotype,NF2_Genotype,"","",""
 Unknown,unknown,"","",FALSE,Sage Bionetworks,nf2Genotype,,"","",NF2_Unknown_Genotype,Class,Biosample,Genotype,NF2_Genotype,"","",""
+Polymeric nanoparticles,"Polymeric nanoparticles (PNPs) are solid and spherical (in most cases) structures prepared from natural or synthetic polymers with drug delivery being known to be one of the most important biomedical applications (reference: Hirvonen et al., Nanoengineered Biomaterials for Advanced Drug Delivery, 2020)","","",FALSE,"",,materialType,"","",Polymeric_Nanoparticles,Class,Sample,Material,"","","",""
+DNA,"DNA (deoxyribonucleic acid) is a polymer of nucleotides and is the genetic material in organisms and some viruses.","","",FALSE,"",,materialType,"","",DNA,Class,Sample,Material,"","","",""
 C57BL/6J,C57BL/6 is the most widely used inbred strain. It is commonly used as a general purpose strain and background strain for the generation of congenics carrying both spontaneous and induced mutations.,"","",FALSE,https://www.jax.org/strain/000664,modelSystemName,,"","",C57BL/6J,Class,Biosample,Model_System,Mouse_Model,"","",""
 NOD scid gamma,"These mice are most often referred to using their branded name NSG™ and are extremely immunodeficient.","","",FALSE,https://www.jax.org/strain/005557,modelSystemName,,"","",NOD_scid_gamma,Class,Biosample,Model_System,Mouse_Model,"","",""
 NRG,"Extremely immunodeficient mice with a targeted knockout mutation in recombination activating gene 1 (Rag1) and a complete null allele of the IL2 receptor common gamma chain.","","",FALSE,https://www.jax.org/strain/007799,modelSystemName,,"","",NRG,Class,Biosample,Model_System,Mouse_Model,"","",""
@@ -504,8 +728,7 @@ tumor,"General term for tumor sample – use when it is unknown when a more spec
 metastatic tumor,"For neoplasms, a non-infiltrating and non-metastasizing neoplastic process that is characterized by the absence of morphologic features associated with malignancy (e.g., severe atypia, nuclear pleomorphism, tumor cell necrosis, and abnormal mitoses).","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C14172,tissue,,"","",Metastatic_Tumor,Class,Biosample,Tumor,"","","",""
 metastatic/recurrent tumor,A tumor with metastatic/recurrent characteristic.,"","",FALSE,"",tissue,,"","",Metastatic_Recurrent_Tumor,Class,Biosample,Tumor,"","","",""
 recurrent tumor,A tumor described with recurrent characteristic.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C4798,tissue,,"","",Recurrent_Tumor,Class,Biosample,Tumor,"","","",""
-tumorType,The type of tumor that the biospecimen used to generate the data were collected from.,"Teratoma, Cutaneous Neurofibroma, Subcutaneous Neurofibroma, Plexiform Neurofibroma, Atypical Neurofibroma, Malignant Peripheral Nerve Sheath Tumor, Glioma, Low-Grade Glioma NOS, Pilocytic Astrocytoma, Atypical Pilocytic Astrocytoma, Pilomyxoid Astrocytoma, Diffuse Astrocytoma, Glioblastoma Multiforme, Anaplastic Pilocytic Astrocytoma, Pleomorphic Xanthoastrocytoma, Oligoastrocytoma, High-Grade Glioma NOS, Unknown, Anaplastic Astrocytoma, Glioblastoma, Schwannoma, Meningioma, Massive Soft 
-Neurofibroma, Diffuse Infiltrating Neurofibroma, Localized Neurofibroma, Neurofibroma with Degenerative Atypia, Neurofibroma, Anaplastic Pleomorphic Xanthoastrocytoma, Ganglioglioma, Anaplastic Ganglioglioma, Optic Pathway Glioma, Not Applicable,Colorectal Carcinoma,Recurrent MPNST,Juvenile Myelomonocytic Leukemia,Sarcoma,Fibromatosis,Fibrosarcoma,Necrotic Neoplasm,Hemorrhagic Neoplasm,NF1-Associated Tumor,NF2-Associated Tumor",,FALSE,Sage Bionetworks,cancer,,,,tumorType,Property,Biosample,annotationProperty,biosampleAnnotation,Tumor,,
+tumorType,The type of tumor that the biospecimen used to generate the data were collected from.,"Teratoma, Cutaneous Neurofibroma, Subcutaneous Neurofibroma, Plexiform Neurofibroma, Atypical Neurofibroma, Malignant Peripheral Nerve Sheath Tumor, Glioma, Low-Grade Glioma NOS, Pilocytic Astrocytoma, Atypical Pilocytic Astrocytoma, Pilomyxoid Astrocytoma, Diffuse Astrocytoma, Glioblastoma Multiforme, Anaplastic Pilocytic Astrocytoma, Pleomorphic Xanthoastrocytoma, Oligoastrocytoma, High-Grade Glioma NOS, Unknown, Anaplastic Astrocytoma, Glioblastoma, Schwannoma, Meningioma, Massive Soft Neurofibroma, Diffuse Infiltrating Neurofibroma, Localized Neurofibroma, Neurofibroma with Degenerative Atypia, Neurofibroma, Anaplastic Pleomorphic Xanthoastrocytoma, Ganglioglioma, Anaplastic Ganglioglioma, Optic Pathway Glioma, Not Applicable,Colorectal Carcinoma,Recurrent MPNST,Juvenile Myelomonocytic Leukemia,Sarcoma,Fibromatosis,Fibrosarcoma,Necrotic Neoplasm,Hemorrhagic Neoplasm,NF1-Associated Tumor,NF2-Associated Tumor",,FALSE,Sage Bionetworks,cancer,,,,tumorType,Property,Biosample,annotationProperty,biosampleAnnotation,Tumor,,
 diagnosis,A diagnosis is the result of a medical investigation to identify a disorder from its signs and symptoms.,"Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis, Unknown, Not Applicable, Sporadic Schwannoma",,FALSE,,experimentalData,,,,diagnosis,Property,Biosample,annotationProperty,,Diagnosis,one,Currently a single NF diagnosis allowed; in the future multiple diagnoses may be allowed for comorbidities.
 bodyPart,"Sample location referring to a named area of the body, inclusive of gross anatomical structures and organ parts. ","head, neck, scalp, leg, pelvis, mesentery, axilla, acetabulum, forearm, muscle, finger, thoracic spine, groin, back, iliac spine, spine, shoulder, scapula, lymph node, kidney, skin, mammary gland, nerves, brain, blood, breast, colon, lung, liver, prostate, pancreas, ovary, spleen, bone marrow, Bursa Of Fabricius, nose",,FALSE,,experimentalData,,,,bodyPart,Property,Biosample,annotationProperty,,Body_Part,,
 organ,A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues. An organ is part of an anatomic system or a body region.,"lymph node, kidney, skin, mammary gland, nerves, brain, blood, breast, colon, lung, liver, prostate, pancreas, ovary, spleen, bone marrow, Bursa Of Fabricius, nose, Eye",,FALSE,,experimentalData,,,,organ,Property,Biosample,annotationProperty,,Organ,,
@@ -531,225 +754,14 @@ age,A numeric value representing age of the individual. Use with ageUnit.,,ageUn
 ageUnit,"A time unit that can be used with a given age value, e.g. years.","days, months, years",,FALSE,Sage Bionetworks,,,,,ageUnit,Property,Biosample,annotationProperty,biosampleAnnotation,,,
 bioSampleUsed,The biosample used.,,,,,,,,,,,,,,,,
 isXenograft,Whether or not sample source is a xenograft (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,isXenograft,DataProperty,Biosample,annotationProperty,,,,
-raw counts,The number or amount of something.,"",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C25463,dataType,,"","",Raw_Counts,Class,Data,Data_Class,"","","",""
-Volume,The amount of three dimensional space occupied by an object or the capacity of a space or container.,"",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C25335,dataType,,"","",Volume,Class,Data,Data_Class,"","","",""
-Weight,The vertical force exerted by a mass as a result of gravity.,"",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C25208,dataType,,"","",Weight,Class,Data,Data_Class,"","","",""
-Pharmacokinetic Study,"A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.","",assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C49663,dataType,,"","",Pharmacokinetic_Study,Class,Data,Data_Class,"","","",""
-genomicVariants,"Genomic alterations, including single nucleotide polymorphisms, short indels and structural variants. Use more specific term if possible, esp. if data is only of one specific subset.","",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Foperation_3227,dataType,,"","",Genomic_Variants,Class,Data,Data_Class,"","","",""
-AlignedReads,"Aligned reads output from alignment workflows","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads,dataType,,"","",Aligned_Reads,Class,Data,Data_Class,"","","",""
-SomaticVariants,"Called somatic variants","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=simple_somatic_mutation,dataType,,"","",Somatic_Variants,Class,Data,Data_Class,"",,"",""
-AnnotatedSomaticVariants,"Somatic variants annotated with some annotation workflow","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=annotated_somatic_mutation,dataType,,"","",Annotated_Somatic_Variants,Class,Data,Data_Class,"","","",""
-GermlineVariants,"Called germline variants","",assay,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=simple_germline_variation,dataType,,"","",Germline_Variants,Class,Data,Data_Class,"","","",""
-AnnotatedGermlineVariants,"Germline variants annotated with some annotation workflow","",assay,FALSE,,dataType,,"","",Annotated_Germline_Variants,Class,Data,Data_Class,"","","",""
-StructuralVariants,"Specifically genomic variants data classified as structural variants, which may be derived from specialized variant calling workflows","",assay,FALSE,,dataType,,"","",Structural_Variants,Class,Data,Data_Class,"","","",""
-behavior process,"The action, reaction, or performance of an organism in response to external or internal stimuli.","",assay,FALSE,hhttps://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=structural_variation,dataType,,"","",Behavior_Process,Class,Data,Data_Class,"","","",""
-metabolomics,"The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism.","",assay,FALSE,http://edamontology.org/topic_3172,dataType,,"","",Metabolomics,Class,Data,Data_Class,"","","",""
-image,Biological or biomedical data that has been rendered into an image.,"",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Fdata_2968,dataType,,"","",Image,Class,Data,Data_Class,"","","",""
-geneExpression,The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data.,"",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Ftopic_0203,dataType,,"","",Gene_Expression,Class,Data,Data_Class,"","","",""
-isoformExpression,Expression of protien isoforms formed from alternative splicings or other post-translational modifications of a single gene through RNA splicing mechanisms.,"",assay,FALSE,https://en.wikipedia.org/wiki/Protein_isoform,dataType,,"","",Isoform_Expression,Class,Data,Data_Class,"","","",""
-proteomics,"Protein and peptide identification, especially in the study of whole proteomes of organisms.","",assay,FALSE,https://www.ebi.ac.uk/ols/ontologies/edam/terms?iri=http%3A%2F%2Fedamontology.org%2Ftopic_0121,dataType,,"","",Proteomics,Class,Data,Data_Class,"","","",""
-kinomics,Kinomics is the study of protein kinases and protein kinase signaling.,"",assay,FALSE,http://www.kinomecore.com/what-is-kinomics/,dataType,,"","",Kinomics,Class,Data,Data_Class,"","","",""
-drugScreen,Information on drug sensitivity and molecular markers of drug response,"",assay,FALSE,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531057/,dataType,,"","",Drug_Screen,Class,Data,Data_Class,"","","",""
-drugCombinationScreen,Information on drug sensitivity of more than one compound,"","",FALSE,https://www.ncbi.nlm.nih.gov/pubmed/29344898,dataType,,"","",Drug_Combination_Screen,Class,Data,Data_Class,"","","",""
-cellularPhysiology,"","",assay,FALSE,"",dataType,,"","",Cellular_Physiology,Class,Data,Data_Class,"","","",""
-chromatinActivity,Chromatin activity that allow access of condensed genomic DNA and potentially control gene expression.,"","",FALSE,https://en.wikipedia.org/wiki/Chromatin_remodeling,dataType,,"","",Chromatin_Activity,Class,Data,Data_Class,"","","",""
-surveyData,A data set that contains the outcome of a survey.,"",assay,FALSE,http://purl.obolibrary.org/obo/OMIABIS_0000060,dataType,,"","",Survey_Data,Class,Data,Data_Class,"","","",""
-network,An interconnected system of things or people.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C61377,dataType,,"","",Network,Class,Data,Data_Class,"","","",""
-clinical,Data obtained through patient examination or treatment.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C15783,dataType,,"","",Clinical_Data,Class,Data,Data_Class,"","","",""
-immunoassay,Laboratory test involving interaction of antigens with specific antibodies.,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C16723,dataType,,"","","","",Data,Data_Class,"","","",""
-electrophysiology,Data generated from an electrophysiology assay.,"","",FALSE,http://purl.obolibrary.org/obo/ERO_0000564,dataType,,"","",Electrophysiology,Class,Data,Data_Class,"","","",""
-mask image,"Image used as the mask for an image processing operation, such as subtraction.","","",FALSE,http://dicom.nema.org/resources/ontology/DCM/121321,dataType,,"","",Mask_Image,Class,Data,Data_Class,"","","",""
-curatedData,"Any file derived from or pertaining a manually or programatically curated data resource. Examples include: reference sequences, drug information databases, identifier maps""""","","",FALSE,"","",,"","",Curated_Data,Class,Data,Data_Class,"","","",""
-normalized,A data set that is produced as the output of a normalization data transformation.,"","",FALSE,http://purl.obolibrary.org/obo/OBI_0000451,dataSubtype,,"","",Normalized,Class,Data,Data_Level,"","","",""
-dataMatrix,A file of data containing multiple values for multiple samples.,"","",FALSE,"",dataSubtype,,"","",Data_Matrix,Class,Data,Data_Level,"","","",""
-raw,"A data file produced by an instrument, or one with very little subsequent processing.","","",FALSE,"",dataSubtype,,"","",Raw,Class,Data,Data_Level,"","","",""
-processed,A file of data generated from running one or more bioinformatics methods on a raw file.,"","",FALSE,"",dataSubtype,,"","",Processed,Class,Data,Data_Level,"","","",""
-metadata,"A file of clinical, technical, or other parameters that describe a dataset.","","",FALSE,"",dataSubtype,,"","",Metadata,Class,Data,Data_Level,"","","",""
-representative,"An activity that stands as an equivalent of something or results in an equivalent; typical of, or the same as, others in a larger group of people or things.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C67045,dataSubtype,,"","",Representative,Class,Data,Data_Level,"","","",""
-bash script,Bash Shell Script,"","",FALSE,https://en.wikipedia.org/wiki/Shell_script,fileFormat,,"","",bash_script,Class,Data,File_Format,Open_Format,"","",""
-bedgraph,Holds a tab-delimited chromosome /start /end / datavalue dataset. The bedGraph format allows display of continuous-valued data in track format. This display type is useful for probability scores and transcriptome data,"","",FALSE,http://edamontology.org/format_3583,fileFormat,,"","",bedgraph,Class,Data,File_Format,Open_Format,"","",""
-ai,Adobe Illustrator format,"","",FALSE,http://www.ebi.ac.uk/swo/data/SWO_3000023,fileFormat,,"","",ai,Class,Data,File_Format,Proprietary_Format,"","",""
-idx,"","","",FALSE,"",fileFormat,,"","",idx,Class,Data,File_Format,"","","",""
-idat,Proprietary file format for (raw) BeadArray data used by genomewide profiling platforms from Illumina Inc. This format is output directly from the scanner and stores summary intensities for each probe-type on an array.,"","",FALSE,http://edamontology.org/format_3578,fileFormat,,"","",idat,Class,Data,File_Format,Proprietary_Format,"","",""
-bam,"BAM format, the binary, BGZF-formatted compressed version of SAM format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s)","","",FALSE,http://edamontology.org/format_2572,fileFormat,,"","",bam,Class,Data,File_Format,Open_Format,"","",""
-bai,BAM indexing format,"","",FALSE,http://edamontology.org/format_3327,fileFormat,,"","",bai,Class,Data,File_Format,Open_Format,"","",""
-excel,Microsoft Excel spreadsheet format,"","",FALSE,"",fileFormat,,"","",excel,Class,Data,File_Format,Proprietary_Format,"","",""
-powerpoint,Microsoft Powerpoint slide format,"","",FALSE,"",fileFormat,,"","",powerpoint,Class,Data,File_Format,Proprietary_Format,"","",""
-tif,"Tagged Image File Format, abbreviated TIFF or TIF, is a computer file format for storing raster graphics images","","",FALSE,https://en.wikipedia.org/wiki/TIFF,fileFormat,,"","",tif,Class,Data,File_Format,Preferred_Open_Format,"","",""
-png,PNG is a file format for image compression,"","",FALSE,http://edamontology.org/format_3603,fileFormat,,"","",png,Class,Data,File_Format,Open_Format,"","",""
-doc,Microsoft Word document format,"","",FALSE,"",fileFormat,,"","",doc,Class,Data,File_Format,Proprietary_Format,"","",""
-pdf,Portable Document Format,"","",FALSE,http://edamontology.org/format_3508,fileFormat,,"","",pdf,Class,Data,File_Format,Proprietary_Format,"","",""
-hdf,"Hierarchical Data Format (HDF) is a set of file formats (HDF4, HDF5) designed to store and organize large amounts of data","","",FALSE,https://en.wikipedia.org/wiki/Hierarchical_Data_Format,fileFormat,,"","",hdf,Class,Data,File_Format,Open_Format,"","",""
-fasta,"FASTA format is a text-based format for representing either nucleotide sequences or peptide sequences, in which nucleotides or amino acids are represented using single-letter codes","","",FALSE,https://en.wikipedia.org/wiki/FASTA_format,fileFormat,,"","",fasta,Class,Data,File_Format,Preferred_Open_Format,"","",""
-fastq,FASTQ format is a text-based format for storing both a biological sequence (usually nucleotide sequence) and its corresponding quality scores. Both the sequence letter and quality score are each encoded with a single ASCII character for brevity,"","",FALSE,https://en.wikipedia.org/wiki/FASTQ_format,fileFormat,,"","",fastq,Class,Data,File_Format,Preferred_Open_Format,"","",""
-sam,Sequence Alignment/Map (SAM) format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s),"","",FALSE,http://edamontology.org/format_2573,fileFormat,,"","",sam,Class,Data,File_Format,Open_Format,"","",""
-vcf,"Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)","","",FALSE,http://edamontology.org/format_3016,fileFormat,,"","",vcf,Class,Data,File_Format,Open_Format,"","",""
-bcf,"BCF, the binary version of Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)","","",FALSE,http://edamontology.org/format_3016,fileFormat,,"","",bcf,Class,Data,File_Format,Open_Format,"","",""
-maf,"Multiple Alignment Format (MAF) supporting alignments of whole genomes with rearrangements, directions, multiple pieces to the alignment, and so forth","","",FALSE,http://edamontology.org/format_3008,fileFormat,,"","",maf,Class,Data,File_Format,Open_Format,"","",""
-bed,"Browser Extensible Data (BED) format of sequence annotation track, typically to be displayed in a genome browser","","",FALSE,http://edamontology.org/format_3003,fileFormat,,"","",bed,Class,Data,File_Format,Open_Format,"","",""
-chp,CHP file contains probe set analysis results generated from Affymetrix software,"","",FALSE,"",fileFormat,,"","",chp,Class,Data,File_Format,Proprietary_Format,"","",""
-cel,Format of Affymetrix data file of information about (raw) expression levels of the individual probes,"","",FALSE,http://edamontology.org/format_1638,fileFormat,,"","",cel,Class,Data,File_Format,Proprietary_Format,"","",""
-sif,SIF (simple interaction file) Format - a network/pathway format used for instance in cytoscape,"","",FALSE,http://edamontology.org/format_3619,fileFormat,,"","",sif,Class,Data,File_Format,"","","",""
-tsv,Tabular data represented as tab-separated values in a text file,"","",FALSE,http://edamontology.org/format_3475,fileFormat,,"","",tsv,Class,Data,File_Format,Preferred_Open_Format,"","",""
-csv,Tabular data represented as comma-separated values in a text file,"","",FALSE,http://edamontology.org/format_3752,fileFormat,,"","",csv,Class,Data,File_Format,Preferred_Open_Format,"","",""
-txt,Textual format,"","",FALSE,http://edamontology.org/format_2330,fileFormat,,"","",txt,Class,Data,File_Format,Preferred_Open_Format,"","",""
-plink,Any Plink file format (MAP/PED/BED/BIM/FAM),"","",FALSE,https://www.cog-genomics.org/plink2/formats,fileFormat,,"","",plink,Class,Data,File_Format,Open_Format,"","",""
-bigwig,bigWig format for large sequence annotation tracks that consist of a value for each sequence position,"","",FALSE,http://edamontology.org/format_3006,fileFormat,,"","",bigwig,Class,Data,File_Format,Open_Format,"","",""
-wiggle,Wiggle format (WIG) of a sequence annotation track that consists of a value for each sequence position,"","",FALSE,http://edamontology.org/format_3005,fileFormat,,"","",wiggle,Class,Data,File_Format,Open_Format,"","",""
-gct,"Tab-delimited text files of GenePattern that contain a column for each sample, a row for each gene, and an expression value for each gene in each sample","","",FALSE,http://edamontology.org/format_3709,fileFormat,,"","",gct,Class,Data,File_Format,"","","",""
-bgzip,Blocked GNU Zip format,"","",FALSE,http://edamontology.org/format_3615,fileFormat,,"","",bgzip,Class,Data,File_Format,Open_Format,"","",""
-zip,zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification,"","",FALSE,http://purl.obolibrary.org/obo/OBI_0000325,fileFormat,,"","",zip,Class,Data,File_Format,Open_Format,"","",""
-seg,SEG file (segmented data; .seg or .cbs) is a tab-delimited text file that lists loci and associated numeric values,"","",FALSE,https://software.broadinstitute.org/software/igv/SEG,fileFormat,,"","",seg,Class,Data,File_Format,Open_Format,"","",""
-html,HTML format,"","",FALSE,http://edamontology.org/format_2331,fileFormat,,"","",html,Class,Data,File_Format,"","","",""
-mov,A video file format with the .mov extension,"","",FALSE,Sage Bioenetworks,fileFormat,,"","",mov,Class,Data,File_Format,"","","",""
-hyperlink,"A reference (link) from some point in one hypertext document to another document, another place in the same document, or a website.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C47919,fileFormat,,"","",hyperlink,Class,Data,File_Format,"","","",""
-svs,"A single-file pyramidal tiled TIFF, with non-standard metadata and compression.","","",FALSE,https://openslide.org/formats/aperio/,fileFormat,,"","",svs,Class,Data,File_Format,"","","",""
-md,Markdown (MD) is a lightweight markup language with plain text formatting syntax,"","",FALSE,https://en.wikipedia.org/wiki/Markdown,fileFormat,,"","",md,Class,Data,File_Format,"","","",""
-flagstat,Output of samtools flagstat tool,"","",FALSE,"",fileFormat,,"","",flagstat,Class,Data,File_Format,"","","",""
-gtf,Gene transfer format (GTF) is a file format used to hold information about gene structure,"","",FALSE,https://en.wikipedia.org/wiki/Gene_transfer_format,fileFormat,,"","",gtf,Class,Data,File_Format,"","","",""
-raw,Proprietary file format for mass spectrometry data from Thermo Scientific,"","",FALSE,http://edamontology.org/format_3712,fileFormat,,"","",raw,Class,Data,File_Format,"","","",""
-msf,Proprietary mass-spectrometry format of Thermo Scientific's ProteomeDiscoverer software,"","",FALSE,http://edamontology.org/format_3702,fileFormat,,"","",msf,Class,Data,File_Format,"","","",""
-rmd,markdown document specific to r analyses,"","",FALSE,http://rmarkdown.rstudio.com/developer_document_templates.html,fileFormat,,"","",rmd,Class,Data,File_Format,"","","",""
-bed narrowPeak,"This format is used to provide called peaks of signal enrichment based on pooled, normalized (interpreted) data. It is a BED6+4 format.","","",FALSE,http://genome.ucsc.edu/FAQ/FAQformat.html#format12,fileFormat,,"","",bed_narrowPeak,Class,Data,File_Format,"","","",""
-bed broadPeak,"This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data. It is a BED 6+3 format.","","",FALSE,http://genome.ucsc.edu/FAQ/FAQformat.html#format13,fileFormat,,"","",bed_broadPeak,Class,Data,File_Format,"","","",""
-bed gappedPeak,"This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data where the regions may be spliced or incorporate gaps in the genomic sequence. It is a BED12+3 format.","","",FALSE,http://genome.ucsc.edu/FAQ/FAQformat.html#format14,fileFormat,,"","",bed_gappedPeak,Class,Data,File_Format,"","","",""
-avi,AVI files can contain both audio and video data in a file container that allows synchronous audio-with-video playback.,"","",FALSE,https://en.wikipedia.org/wiki/Audio_Video_Interleave,fileFormat,,"","",avi,Class,Data,File_Format,"","","",""
-pzfx,"A PZFX file is a Prism project created by GraphPad Prism, a scientific application used to analyze and graph data. It contains project data including graphs and layouts, notes, and tables.","","",FALSE,https://fileinfo.com/extension/pzfx,fileFormat,,"","",pzfx,Class,Data,File_Format,"","","",""
-fig,"Line drawing saved in the Xfig format; stored as a vector image that may include lines, shapes, arcs, splines, arrows, and text objects; may also include images, colors, and patterns.","","",FALSE,https://fileinfo.com/extension/fig,fileFormat,,"","",fig,Class,Data,File_Format,"","","",""
-xml,eXtensible Markup Language (XML) format.,"","",FALSE,http://edamontology.org/format_2332,fileFormat,,"","",xml,Class,Data,File_Format,Preferred_Open_Format,"","",""
-tar,tape archive,"","",FALSE,https://en.wikipedia.org/wiki/Tar_(computing),fileFormat,,"","",tar,Class,Data,File_Format,"","","",""
-R script,R script with expected extension “.R”.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",R_script,Class,Data,File_Format,"","","",""
-abf,The Axon Binary File format (ABF) was created for the storage of binary experimental data.,"","",FALSE,https://mdc.custhelp.com/euf/assets/content/ABFHelp.pdf,fileFormat,,"","",abf,Class,Data,File_Format,"","","",""
-bpm,A beaded pool manifest. Describe the SNP or probe content on a BeadChip or in an assay pool.,"","",FALSE,https://support.illumina.com/datafiles.html,fileFormat,,"","",bpm,Class,Data,File_Format,"","","",""
-dat,Format of Affymetrix data file of raw image data.,"","",FALSE,http://edamontology.org/format_1637,fileFormat,,"","",dat,Class,Data,File_Format,"","","",""
-jpg,Joint Picture Group file format for lossy graphics file.,"","",FALSE,http://edamontology.org/format_3579,fileFormat,,"","",jpg,Class,Data,File_Format,"","","",""
-locs,Illumina iScan bead location file.,"","",FALSE,https://support.illumina.com/content/dam/illumina-support/documents/documentation/system_documentation/iscan/iscan-system-guide-11313539-01.pdf,fileFormat,,"","",locs,Class,Data,File_Format,"","","",""
-Sentrix descriptor file,A BeadScan specific file needed to perform scan setting checks for different array formats and assay type.,"","",FALSE,https://support.illumina.com/content/dam/illumina-support/documents/myillumina/dd0aff11-2664-481b-a8ce-26831a907cae/beadscan_3.0_software_addendum.pdf,fileFormat,,"","",Sentrix_descriptor_file,Class,Data,File_Format,"","","",""
-Python script,Python script with expected extension “.py”.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",Python_script,Class,Data,File_Format,"","","",""
-MATLAB script,A MATLAB script file with expected extension “.m”. Note that files with a “.mat” extension contains MATLAB formatted data.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",MATLAB_script,Class,Data,File_Format,"","","",""
-MATLAB data,A MATLAB formatted data file with expected extension “.mat”.,"","",FALSE,Sage Bionetworks,fileFormat,,"","",MATLAB_data,Class,Data,File_Format,"","","",""
-sav,"The SPSS Statistics File Format is a proprietary binary format, developed and maintained as the native format for the SPSS statistical software application.","","",FALSE,https://www.loc.gov/preservation/digital/formats/fdd/fdd000469.shtml,fileFormat,,"","",sav,Class,Data,File_Format,"","","",""
-gzip,GZipped format,"","",FALSE,http://purl.obolibrary.org/obo/NCIT_C80220,fileFormat,,"","",gzip,Class,Data,File_Format,"","","",""
-sdf,SDF is one of a family of chemical-data file formats developed by MDL Information Systems; it is intended especially for structural information.,"","",FALSE,http://edamontology.org/format_3814,fileFormat,,"","",sdf,Class,Data,File_Format,"","","",""
-RData,"The RData format (usually with extension .rdata or .rda) is a format designed for use with R, a system for statistical computation and related graphics, for storing a complete R workspace or selected 'objects' from a workspace in a form that can be loaded back by R.","","",FALSE,https://www.loc.gov/preservation/digital/formats/fdd/fdd000470.shtml,fileFormat,,"","",RData,Class,Data,File_Format,"","","",""
-hic,Hi-C contact matrix file,"","",FALSE,https://github.com/theaidenlab/juicer/wiki/Data,fileFormat,,"","",hic,Class,Data,File_Format,"","","",""
-ab1,TAB1 binary format of raw DNA sequence reads (output of Applied Biosystems' sequencing analysis software). Contains an electropherogram and the DNA base sequence.,"","",FALSE,http://edamontology.org/format_3000,fileFormat,,"","",ab1,Class,Data,File_Format,"","","",""
-7z,"A compressed archive file format that supports several different data compression, encryption and pre-processing filters.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C80224,fileFormat,,"","",7z,Class,Data,File_Format,"","","",""
-gff3,Generic Feature Format version 3 (GFF3) of sequence features.,"","",FALSE,http://edamontology.org/format_1975,fileFormat,,"","",gff3,Class,Data,File_Format,"","","",""
-json,"JavaScript Object Notation format; a lightweight, text-based format to represent tree-structured data using key-value pairs.","","",FALSE,http://edamontology.org/format_3464,fileFormat,,"","",json,Class,Data,File_Format,"","","",""
-sqlite,Data format used by the SQLite database.,"","",FALSE,http://edamontology.org/format_3621,fileFormat,,"","",sqlite,Class,Data,File_Format,"","","",""
-svg,Scalable Vector Graphics (SVG) is an XML-based vector image format for two-dimensional graphics with support for interactivity and animation.,"","",FALSE,http://edamontology.org/format_3604,fileFormat,,"","",svg,Class,Data,File_Format,"","","",""
-sra,SRA archive format (SRA) is the archive format used for input to the NCBI Sequence Read Archive.,"","",FALSE,http://edamontology.org/format_3698,fileFormat,,"","",sra,Class,Data,File_Format,"","","",""
-recal,.recal file from GATK VQSR,"","",FALSE,https://software.broadinstitute.org/gatk/documentation/tooldocs/3.8-0/org_broadinstitute_gatk_tools_walkers_variantrecalibration_VariantRecalibrator.php#--recal_file,fileFormat,,"","",recal,Class,Data,File_Format,"","","",""
-tranches,.tranches file from GATK VQSR,"","",FALSE,https://software.broadinstitute.org/gatk/documentation/tooldocs/3.8-0/org_broadinstitute_gatk_tools_walkers_variantrecalibration_VariantRecalibrator.php#--tranches_file,fileFormat,,"","",tranches,Class,Data,File_Format,"","","",""
-mtx,Matrix Market Exchange Format,"","",FALSE,https://math.nist.gov/MatrixMarket/formats.html#MMformat,fileFormat,,"","",mtx,Class,Data,File_Format,"","","",""
-tagAlign,Tag Alignment provides genomic mapping of short sequence tags.,"","",FALSE,https://genome.ucsc.edu/FAQ/FAQformat.html#format15,fileFormat,,"","",tagAlign,Class,Data,File_Format,"","","",""
-dup,output of the Picard MarkDuplicates tool.,"","",FALSE,https://software.broadinstitute.org/gatk/documentation/tooldocs/4.0.4.0/picard_sam_markduplicates_MarkDuplicates.php,fileFormat,,"","",dup,Class,Data,File_Format,"","","",""
-DICOM,"A comprehensive set of standards for communications between medical imaging devices, including handling, storing and transmitting information in medical imaging. It includes a file format definition and a network communication protocol.","","",FALSE,http://purl.obolibrary.org/obo/NCIT_C49059,fileFormat,,"","",DICOM,Class,Data,File_Format,"","","",""
-czi,"microscopy imaging file format that saves multidimensional images such as time lapse, Z-stacks, multiposition experiments and virtual slides, combined with relevant meta information","","",FALSE,https://www.zeiss.com/microscopy/int/products/microscope-software/zen/czi.html,fileFormat,,"","",czi,Class,Data,File_Format,"","","",""
-mzML,"mzML format for raw spectrometer output data, standardised by HUPO PSI MSS.","","",FALSE,http://edamontology.org/format_3244,fileFormat,,"","",mzML,Class,Data,File_Format,Preferred_Open_Format,"","",""
-SPAR,Phillips MRS Header File,"","",FALSE,https://github.com/chenkonturek/MRS_MRI_libs,fileFormat,,"","",SPAR,Class,Data,File_Format,"","","",""
-SDAT,Phillips MRS Data File,"","",FALSE,https://github.com/chenkonturek/MRS_MRI_libs,fileFormat,,"","",SDAT,Class,Data,File_Format,"","","",""
-nii,"NIfTI-1 can store image data from any modality such as PET, MRI, CT, EEG that produces regularly sampled 1-5D rasters.","","",FALSE,https://nifti.nimh.nih.gov/nifti-1/documentation/faq,fileFormat,,"","",nii,Class,Data,File_Format,"","","",""
-PAR,This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).,"","",FALSE,https://nipy.org/nibabel/reference/nibabel.parrec.html,fileFormat,,"","",PAR,Class,Data,File_Format,"","","",""
-REC,This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).,"","",FALSE,https://nipy.org/nibabel/reference/nibabel.parrec.html,fileFormat,,"","",REC,Class,Data,File_Format,"","","",""
-hdr,"MRI Header file, as in the NIFTI-1 Analyze 7.5 format","","",FALSE,https://nifti.nimh.nih.gov/pub/dist/src/niftilib/nifti1.h,fileFormat,,"","",hdr,Class,Data,File_Format,"","","",""
-img,"MRI Data file, as in the NIFTI-1 Analyze 7.5 format","","",FALSE,https://nifti.nimh.nih.gov/pub/dist/src/niftilib/nifti1.h,fileFormat,,"","",img,Class,Data,File_Format,"","","",""
-sf,"Salmon’s main output is its quantification file. This file is a plain-text, tab-separated file with a single header line (which names all of the columns).","","",FALSE,https://salmon.readthedocs.io/en/latest/file_formats.html,fileFormat,,"","",sf,Class,Data,File_Format,"","","",""
-tom,"The .tom format is a specialized 3D image export format from the Vectra medical imaging systems that can optionally preserve trimmings and/or landmarks.","","",FALSE,http://canfieldupgrade.com/assets/media/VECTRA-M3-User-Guide.pdf,fileFormat,,"","",tom,Class,Data,File_Format,"","","",""
-gene symbol,A unique gene name approved by an organism specific nomenclature committee.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C43568,curatedDataType,,,,Gene_Symbol,Class,Data,Metadata,,,,
-clinical data,Data obtained through patient examination or treatment.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C15783,curatedDataType,,,,Clinical_Curated_Data,Class,Data,Metadata,,,,
-gene function,A term that expresses the function of a gene product.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C48933,curatedDataType,,,,Gene_Function,Class,Data,Metadata,,,,
-chemical descriptor,"A chemical descriptor is a data item (quantity or value) about a chemical entity that conforms to a specification for how it is calculated, measured or recorded.",,,FALSE,http://semanticscience.org/resource/CHEMINF_000123,curatedDataType,,,,Chemical_Descriptor,Class,Data,Metadata,,,,
-individual,Metadata describing properties of individuals (human or animal) represented in the study.,,,FALSE,Sage Bionetworks,metadataType,,,,Individual_Annotation,Class,Data,Metadata,,,,
-biospecimen,Metadata describing properties of specimens collected and/or analyzed in the study.,,,FALSE,Sage Bionetworks,metadataType,,,,Biospecimen_Annotation,Class,Data,Metadata,,,,
-assay,Metadata describing properties of an assay conducted in the study.,,,FALSE,Sage Bionetworks,metadataType,,,,Assay_Annotation,Class,Data,Metadata,,,,
-data dictionary,Metadata describing terms or variables that appear in another file.,,,FALSE,Sage Bionetworks,metadataType,,,,Data_Dictionary,Class,Data,Metadata,,,,
-manifest,Metadata describing a list of files and the annotations terms associated with them.,,,FALSE,Sage Bionetworks,metadataType,,,,Manifest,Class,Data,Metadata,,,,
-protocol,"A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",,,FALSE,http://purl.obolibrary.org/obo/OBI_0000272,metadataType,,,,Protocol,Class,Data,Metadata,,,,
-GRCh38,Genome Reference Consortium Human Build 38,,,FALSE,https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.26,referenceSet,,,,GRCh38,Class,Data,Metadata,,,,
-GRCh37,Genome Reference Consortium Human Build 37,,,FALSE,https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.13/,referenceSet,,,,GRCh37,Class,Data,Metadata,,,,
-MMUL1.0,Ensembl preliminary assembly Macaca mulatta,,,FALSE,https://jul2016.archive.ensembl.org/Macaca_mulatta/Info/Index,referenceSet,,,,MMUL1.0,Class,Data,Metadata,,,,
-HRC,Human haplotype reference panel,,,FALSE,http://www.haplotype-reference-consortium.org,referenceSet,,,,HRC,Class,Data,Metadata,,,,
-experimentalData,"Any file derived from or pertaining to a scientific experiment. experimentalData annotations should be applied, possibly disease-related",,,FALSE,Sage Bionetworks,resourceType,,,,Experimental_Data,Class,Data,Metadata,Resource,,,
-result,"Any file that reports data results. Examples include figures, presentations, analysis, etc.",,,FALSE,Sage Bionetworks,resourceType,,,,Result,Class,Data,Metadata,Resource,,,
-tool,"Any file or link that represents a tool, model, or algorithm; the tool annotations could be applied",,,FALSE,Sage Bionetworks,resourceType,,,,Tool,Class,Data,Metadata,Resource,,,
-workflow report,"Workflow-generated reports of analysis of primary data, usually created programmatically at completion of workflow step.",,,FALSE,,resourceType,,,,Workflow_Report,Class,Data,Metadata,Report,,,
-report,"a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).",,,FALSE,http://purl.obolibrary.org/obo/IAO_0000088,resourceType,,,,Report,Class,Data,Metadata,Resource,,,
-metadata,Data about data; information that describes another set of data.,,,FALSE,http://purl.obolibrary.org/obo/NCIT_C52095,resourceType,,,,metadata,Class,Data,Metadata,Resource,,,
-protocol,"A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",,,FALSE,http://purl.obolibrary.org/obo/OBI_0000272,resourceType,,,,Protocol,Class,Data,Metadata,Resource,,,
-curatedDataType,The type of information being curated.,"reference sequence, gene symbol, clinical data, gene function, chemical descriptor",,TRUE,,curatedData,,,,curatedDataType,Property,Data,annotationProperty,,,,
-referenceSet,"A set of references (e.g., canonical assembled contigs) which defines a common coordinate space for comparing reference-aligned experimental data.","GRCh38, GRCh37, MMUL1.0, HRC",,TRUE,,curatedData,,,,referenceSet,Property,Data,annotationProperty,,,,
-reference sequence,Syntactic sequences that has a role as reference of an annotation.,,,FALSE,http://rdf.biosemantics.org/ontologies/rsa#ReferenceSequence,curatedDataType,,,,referenceSequence,Property,Data,annotationProperty,,,,
-dataSubtype,"Further qualification of dataType, which may be used to indicate the state of processing of the data, aggregation of the data, or presence of metadata.","normalized, dataMatrix, raw, processed, metadata, representative",,TRUE,,experimentalData,,,,dataSubtype,Property,Data,annotationProperty,,Data_Level,one,
-metadataType,"For files of dataSubtype: metadata, a description of the type of metadata in the file.","individual, biospecimen, assay, data dictionary, manifest, protocol",,FALSE,,experimentalData,,,,metadataType,Property,Data,annotationProperty,,,,
-dataType,"A type of experimental, clinical, or other data. This typically refers to a high-level data type that can be related to an assay type. For example, a file of dataType `genomicVariants` might have an assay value of `whole genome sequencing`.","Volume, Weight, Pharmacokinetic Study, genomicVariants,behavior process, metabolomics, image, geneExpression, isoformExpression, proteomics, kinomics, drugScreen, drugCombinationScreen, cellularPhysiology, chromatinActivity, surveyData, network, clinical, immunoassay, electrophysiology, raw counts, mask image,AlignedReads,SomaticVariants,AnnotatedSomaticVariants,StructuralVariants,GermlineVariants,AnnotatedGermlineVariants",dataSubtype,TRUE,,experimentalData,,,,dataType,Property,Data,annotationProperty,,Data,one,
-expressionUnit,"Measure used for transcript expression quantification","TPM,RPKM,FPKM,Counts,Other",,TRUE,,experimentalData,,,,expressionUnit,DataProperty,Data,annotationProperty,,,,
-failedQC,Whether the sample or data failed QC checks (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,failedQC,DataProperty,Data,annotationProperty,,,,
-Filename,The name of the file.,,"entityId,fileFormat",TRUE,Sage Bionetworks,NF,,,,fileName,Class,Data,annotationProperty,fileName,,one,Automatically filled when using the curator app.
-programmingLanguage,A computer programming language,"Python, R, MATLAB, Java, C, C++, C#, Javascript, bash",,FALSE,Sage Bionetworks,,,,,programmingLanguage,Property,Data,annotationProperty,ngsParameter,,,
-runtimePlatform,"Runtime platform or script interpreter dependencies (e.g. Java v1, Python 2.3).",,,FALSE,Sage Bionetworks,,,,,runtimePlatform,Property,Data,annotationProperty,ngsParameter,,,
-documentation,URL to any documentation describing the resource and its use.,,,FALSE,Sage Bionetworks,,,,,documentation,Property,Data,annotationProperty,ngsParameter,,,
-resourceType,The type of resource being stored and annotated,"experimentalData, curatedData, result, tool, report, metadata, protocol, workflow report",,TRUE,,sageCommunity,,,,resourceType,Property,Data,annotationProperty,,Resource,,
-fileFormat,"Defined format of the data file, typically corresponding to extension, but sometimes indicating more general group of files produced by the same tool or software","bash script,bedgraph,ai,idx,idat,bam,bai,excel,powerpoint,tif,png,doc,pdf,hdf,fasta,fastq,sam,vcf,bcf,maf,bed,chp,cel,sif,tsv,csv,txt,plink,bigwig,wiggle,gct,bgzip,zip,seg,html,mov,hyperlink,svs,md,flagstat,gtf,raw,msf,rmd,bed narrowPeak,bed broadPeak,bed gappedPeak,avi,pzfx,fig,xml,tar,R script,abf,bpm,dat,jpg,locs,Sentrix descriptor file,Python script,sav,gzip,sdf,RData,hic,ab1,7z,gff3,json,sqlite,svg,sra,recal,tranches,mtx,tagAlign,dup,DICOM,czi,mzML,SPAR,SDAT,nii,PAR,REC,hdr,img,sf,MATLAB script, MATLAB data,tom",,TRUE,,sageCommunity,,,,fileFormat,Property,Data,annotationProperty,,File_Format,one,
-progressReportNumber,"Indicates milestone the  data is associated with. Currently only required for projects funded by NTAP, GFF, and NFRI. For GFF studies, this is the ‘progress report’ timeline. Example: if submitting data for the 6-month milestone report for NTAP, progressReportNumber=1.  Also if submitting data associated with first milestone, progressReportNumber =1","1, 2, 3, 4, 5, 6, 7, 8, 9, 10, Not Applicable",,FALSE,,template,,,,progressReportNumber,DataProperty,Data,annotationProperty,,,one,
-comments,Brief free-text comments that may also be important to understanding the resource.,,,FALSE,Sage Bionetworks,experimentalData,,,,comments,DataProperty,Data,annotationProperty,,,many,
-Resource_id,A UUID for a Resource from the NF Research Tools Database,,,FALSE,Sage Bionetworks,dccProperty,,,,Resource_id,Property,Data,annotationProperty,dccProperty,,,
-initiative,"Refers to a funding initiative. This annotation is usually handled by the DCC or funder, not the researcher. ",,,FALSE,Sage Bionetworks,dccProperty,,,,initiative,Property,Data,annotationProperty,dccProperty,,,
-fundingAgency,Refers to the funding organization for the generated resource. This annotation is handled by the DCC.,,,FALSE,Sage Bionetworks,dccProperty,,,,fundingAgency,Property,Data,annotationProperty,dccProperty,,,
-createdOn,Refers to when the resource was created on the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,createdOn,Property,Data,annotationProperty,synapseProperty,,,
-createdBy,Refers to the user who created the resource on the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,createdBy,Property,Data,annotationProperty,synapseProperty,,,
-modifiedBy,Refers to a user who last modified the resource on the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,modifiedBy,Property,Data,annotationProperty,synapseProperty,,,
-id,The entity id for the resource automatically assigned by the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,id,Property,Data,annotationProperty,synapseProperty,,,
-etag,Synapse employs an Optimistic Concurrency Control (OCC) scheme to handle concurrent updates. The E-Tag changes every time an entity is updated it is used to detect when a client's current representation of an entity is out-of-date.,,,FALSE,Sage Bionetworks,synapseProperty,,,,etag,Property,Data,annotationProperty,synapseProperty,,,
-parentId,"The id of the parent resource, i.e. the parent folder on the platform. ",,,FALSE,Sage Bionetworks,synapseProperty,,,,parentId,Property,Data,annotationProperty,synapseProperty,,,
-benefactorId,The id of the resource from which access control is inherited.,,,FALSE,Sage Bionetworks,synapseProperty,,,,benefactorId,Property,Data,annotationProperty,synapseProperty,,,
-currentVersion,(Versionable entities only) The current version number of the resource.,,,FALSE,Sage Bionetworks,synapseProperty,,,,currentVersion,Property,Data,annotationProperty,synapseProperty,,,
-dataFileHandleId,(Files only) Refers to the id of the file.,,,FALSE,Sage Bionetworks,synapseProperty,,,,dataFileHandleId,Property,Data,annotationProperty,synapseProperty,,,
-contentSize,(Files only) File size calculated by the platform.,,,FALSE,Sage Bionetworks,synapseProperty,,,,contentSize,Property,Data,annotationProperty,synapseProperty,,,
-type,"Refers to the type of the resource on the platform, e.g. “file”.",,,FALSE,Sage Bionetworks,synapseProperty,,,,type,Property,Data,annotationProperty,synapseProperty,,,
-concreteType,Refers to the class model the data platform uses for representing the resource. This is a low-level field set by the platform and is not a user annotation.,,,FALSE,Sage Bionetworks,synapseProperty,,,,concreteType,Property,Data,annotationProperty,synapseProperty,,,
-author,"The author of the resource; preferably use an ORCID ID, GitHub profile link, etc., if available and a text name if not.",,,FALSE,Sage Bionetworks,,,,,,Property,Data,annotationProperty,,,,
-license,Link to a license or name of license applicable for the resource.,,,,,,,,,,,,,,,,
-allograft,"Tissues, cells, or organs transplanted between genetically different individuals of the same species","","",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064591,transplantationType,,"","",Allograft,Class,Experiment,Method,"","","",""
-xenograft,"Tissues, cells or organs transplanted between animals of different species","","transplantationRecipientSpecies,transplantationRecipientTissue",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064593,transplantationType,,"","",Xenograft,Class,Experiment,Method,"","","",""
-autograft,"Transplant comprised of an individual's own tissue, transferred from one part of the body to another.","","transplantationRecipientSpecies,transplantationRecipientTissue",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064592,transplantationType,,"","",Autograft,Class,Experiment,Method,"","","",""
-isograft,"Tissues, cells or organs transplanted between genetically identical individuals","","",FALSE,https://www.ncbi.nlm.nih.gov/mesh/68064596,transplantationType,,"","",Isograft,Class,Experiment,Method,"","","",""
-seconds,"","","",FALSE,"",timePointUnit,,"","",seconds,Class,Experiment,Unit,Time_Unit,"","",""
-minutes,"","","",FALSE,"",timePointUnit,,"","",minutes,Class,Experiment,Unit,Time_Unit,"","",""
-hours,"","","",FALSE,"",timePointUnit,,"","",hours,Class,Experiment,Unit,Time_Unit,"","",""
-days,"","","",FALSE,"",timePointUnit,,"","",days,Class,Experiment,Unit,Time_Unit,"","",""
-weeks,"","","",FALSE,"",timePointUnit,,"","",weeks,Class,Experiment,Unit,Time_Unit,"","",""
-months,"","","",FALSE,"",timePointUnit,,"","",months,Class,Experiment,Unit,Time_Unit,"","",""
-quarters,Time point unit referring to quarters in a year.,"","",FALSE,"","",,"","",quarters,Class,Experiment,Unit,Time_Unit,"","",""
-transplantationType,"Type of transplantation involved in the experiment, derived from MESH","allograft, xenograft, autograft, isograft","transplantationRecipientSpecies,transplantationRecipientTissue",FALSE,Sage Bionetworks,cancer,,,,transplantationType,Property,Experiment,annotationProperty,transplantationCharacteristic,,,
-transplantationRecipientSpecies,Species into which donor tissue was grown,"Human, Mouse",,FALSE,Sage Bionetworks,cancer,,,,transplantationRecipientSpecies,Property,Experiment,annotationProperty,transplantationCharacteristic,,,
-timePointUnit,For timed experiments this represents the unit of time measured,"seconds, minutes, hours, days, weeks, months, quarters",,FALSE,Sage Bionetworks,cancer,,,,timePointUnit,Property,Experiment,annotationProperty,,Time_Unit,,
-experimentalCondition,A free-text description of the experimental condition (e.g. 5 mM doxorubicin).,,,FALSE,Sage Bionetworks,sageCommunity,,,,experimentalCondition,Property,Experiment,annotationProperty,experimentProperty,,,
-experimentalTimepoint,The numeric value indicating the time elapsed from the beginning of the experiment at which the specimen was collected. Use in tandem with timePointUnit,,timePointUnit,FALSE,Sage Bionetworks,sageCommunity,,,,experimentalTimepoint,Property,Experiment,annotationProperty,experimentProperty,,,
-transplantationRecipientTissue,Tissue into which a xenograph sample is transplanted,,,FALSE,Sage Bionetworks,sageCommunity,,,,transplantationRecipientTissue,Property,Experiment,annotationProperty,,,,
-experimentId,"When applicable, an optional identifier that can be used to distinguish or group the experiments that generated the data; also can be used to denote internal batch reference if needed.",,,FALSE,Sage Bionetworks,sageCommunity,,,,experimentId,Property,Experiment,annotationProperty,experimentProperty,,,
-compoundName,"Common name for a compound, e.g. “Selumetinib” (https://pubchem.ncbi.nlm.nih.gov/compound/10127622)",,InChIKey,FALSE,Sage Bionetworks,sageCommunity,,,,compoundName,Property,Experiment,annotationProperty,experimentProperty,,,
-compoundDose,A dose quantity for the treatment compound. To be used with compoundDoseUnit.,,compoundDoseUnit,FALSE,Sage Bionetworks,sageCommunity,,,,compoundDose,Property,Experiment,annotationProperty,experimentProperty,,,
-compoundDoseUnit,A unit associated with the value(s) in compoundDose.,,,FALSE,Sage Bionetworks,sageCommunity,,,,compoundDoseUnit,Property,Experiment,annotationProperty,experimentProperty,,,
-InChIKey,"A unique hash key for a compound, e.g. for “Selumetinib”, the key is CYOHGALHFOKKQC-UHFFFAOYSA-N (https://pubchem.ncbi.nlm.nih.gov/compound/10127622#section=InChI-Key). This is a more reliable identifier than the compound name and should be used if available.",,,FALSE,Sage Bionetworks,sageCommunity,,,,InChIKey,Property,Experiment,annotationProperty,experimentProperty,,,
-genePerturbationType,Specific way in which a single gene was perturbed in a sample,"overexpression, knockdown, knockout, non-targeting control, Not Applicable",,FALSE,Sage Bionetworks,cancer,,,,genePerturbationType,Property,Experiment,annotationProperty,,Gene_Perturbation,,
-genePerturbationTechnology,Technology used to perform gene perturbation,"RNAi, CRISPR, CRE Recombinase",,FALSE,Sage Bionetworks,cancer,,,,genePerturbationTechnology,Property,Experiment,annotationProperty,,Gene_Perturbation_Technology,,
-genePerturbed,The HUGO gene symbol for the gene that is perturbed.,,"genePerturbationType,genePerturbationTechnology",FALSE,Sage Bionetworks,sageCommunity,,,,genePerturbed,Property,Assay,annotationProperty,experimentProperty,,,
-JAX,The Jackson Laboratory,"","",FALSE,https://www.jax.org,individualIdSource,,"","",JAX,Class,Other,Organization,"","","",""
-sageCommunity,"","","",FALSE,"","",,"","","",Class,Other,Organization,"","","",""
-workflow,"Name and version of the workflow used to generate/analyze the data",,workflowLink,FALSE,,,,,,workflow,Property,Processing,annotationProperty,,,,
-workflowLink,"Workflow URL reference",,,FALSE,,,,,,workflowLink,Property,Processing,annotationProperty,,,,
-genomicReference,"Version of genome reference used for alignment in processing workflow",,,FALSE,,,,,,genomicReference,Property,Processing,annotationProperty,,,,
-averageInsertSize,"Average insert size as reported by samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=average_insert_size,,,,,averageInsertSize,Property,Processing,annotationProperty,,,,
-averageReadLength,"Average read length collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=average_read_length,,,,,averageReadLength,Property,Processing,annotationProperty,,,,
-averageBaseQuality,"Average base quality collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=average_base_quality,,,,,averageBaseQuality,Property,Processing,annotationProperty,,,,
-pairsOnDifferentChr,"Pairs on different chromosomes collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=pairs_on_diff_chr,,,,,pairsOnDifferentChr,Property,Processing,annotationProperty,,,,
-readsDuplicatedPercent,"Percent of duplicated reads collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_reads_duplicated,,,,,readsDuplicatedPercent,Property,Processing,annotationProperty,,,,
-readsMappedPercent,"Percent of mapped reads collected from samtools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_reads_mapped,,,,,readsMappedPercent,Property,Processing,annotationProperty,,,,
-meanCoverage,"Mean coverage for whole genome sequencing, or mean target coverage for whole exome and targeted sequencing, collected from Picard Tools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=mean_coverage,,,,,meanCoverage,Property,Processing,annotationProperty,,,,
-proportionCoverage10x,"Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 10X or greater coverage from Picard Tools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_coverage_10x,,,,,proportionCoverage10x,Property,Processing,annotationProperty,,,,
-proportionCoverage30x,"Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 30X or greater coverage from Picard Tools",,,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=aligned_reads&anchor=proportion_coverage_30x,,,,,proportionCoverage30x,Property,Processing,annotationProperty,,,,
+sourceName," identifies the source from where the sample is derived. If the sample assayed is a nanoparticle sample or some chemical substance not derived from a biological material, then the corresponding source name should refer to the starting sample that was modified by a protocol for the assay.","",,TRUE,,sourceName,,,,sourceName,Property,Sample,annotationProperty,,,,
+sampleType,"Type of sample","",,FALSE,,sampleType,,,,molecularSpecies,Property,Sample,annotationProperty,,,,"Not used directly in template since each template already implicitly assumes either a biospecimen sample or chemical sample; this is a super-property for organization purposes"
+materialType,"Type of material in the characterization","nanoparticles,polymeric nanoparticles,small molecule,DNA",,FALSE,,sampleType,,,,materialType,Property,Material,annotationProperty,,,,
+pH,"Numeric value for pH sample parameter","",,FALSE,,parameter,,,,pH,Property,Sample,annotationProperty,,,,
+concentrationMaterial,"Numeric value for concentration of the material","",,FALSE,,parameter,,,,concentration,DataProperty,Sample,annotationProperty,,,,
+concentrationMaterialUnit,"Unit used for the material concentration, e.g. mg/mL","mg/mL,mM",,FALSE,,parameter,,,,concentrationUnit,Property,Sample,annotationProperty,,,,
+concentrationNaCl,"Numeric value for NaCl concentration","",,FALSE,,parameter,,,,concentrationNaCl,DataProperty,Sample,annotationProperty,,,,
+concentrationNaClUnit,"Unit used for the NaCl concentration, e.g. mM","mg/mL,mM",,FALSE,,parameter,,,,concentrationNaClUnit,Property,Sample,annotationProperty,,,,
 Component,"Category of metadata manifest; provide the same one for all items/rows.",,,TRUE,https://w3id.org/biolink/vocab/category,,,,,,,,,,,,
 genomicsAssayTemplateNormalized,"Generic template for describing raw data from a genomic type assay (RNA-seq, Exome-seq, etc) WITHOUT full individual and biospecimen data. To link individual and biospecimen metadata, an additional “biospecimenTemplate_Default” must be additionally completed with either specimenID or aliquotID available for joining. This is a two-step template.",,"Component,Filename,resourceType,progressReportNumber,dataType,assay,platform,specimenID,aliquotID,runType,libraryPrep,comments",TRUE,Sage Bionetworks,template,,,,Genomics_Assay_Template_Normalized,Class,Template,Template,Assay_Template,,,
 genomicsAssayTemplate,"Generic denormalized template for describing raw data from a genomic type assay (RNA-seq, Exome-seq, etc) along with individual, biospecimen and experimental metadata. This is a one-step template.",,"Component,Filename,resourceType,progressReportNumber,dataType,assay,platform,individualID,parentSpecimenID,runType,libraryPrep,comments",TRUE,Sage Bionetworks,template,,,,Genomics_Assay_Template,Class,Template,Template,Assay_Template,,,
@@ -785,3 +797,4 @@ experimentComponent,Template component for describing core experimental paramete
 genePerturbComponent,Template component for adding genetic perturbation metadata. This applies only to some assays and does not make sense with e.g. behavioral assays.,"genePerturbed,genePerturbationType,genePerturbationTechnology","genePerturbed,genePerturbationType,genePerturbationTechnology",FALSE,Sage Bionetworks,template,,,,Gene_Perturb_Component,Class,Template,TemplateComponent,,,,
 fileComponent,Template component for describing some file on the NF-OSI Synapse platform.,"Filename,entityId,fileFormat,resourceType","Filename,entityId,fileFormat,resourceType",FALSE,Sage Bionetworks,template,,,,File_Component,Class,Template,TemplateComponent,,,,
 ngsComponent,Template component capturing Next Gen Sequencing/genomics attributes.,"runType,readPair,isStranded,readPairOrientation,readStrandOrigin,libraryPrep,libraryPreparationMethod,dissociationMethod,readLength,nucleicAcidSource","runType,readPair,isStranded,readPairOrientation,readStrandOrigin,libraryPrep,libraryPreparationMethod,dissociationMethod,readLength,nucleicAcidSource",FALSE,Sage Bionetworks,template,,,,NGS_Component,Class,Template,TemplateComponent,,,,
+DynamicLightScatteringTemplate,"Template for dynamic light scattering data adapted from ISA-TAB-Nano specs (https://wiki.nci.nih.gov/display/icr/isa-tab-nano)",,"Component,Filename,resourceType,dataType,assay,materialType,pH,concentrationMaterial,concentrationMaterialUnit,concentrationNaCl,concentrationNaClUnit",FALSE,Sage Bionetworks,template,,,,Dynamic_Light_Scattering_Template,Class,Template,Template,,,,
diff --git a/NF.jsonld b/NF.jsonld
index 1131329a..99d24058 100644
--- a/NF.jsonld
+++ b/NF.jsonld
@@ -3602,6 +3602,72 @@
             ],
             "sms:validationRules": []
         },
+        {
+            "@id": "bts:DynamicLightScattering",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Dynamic Light Scattering (DLS), also known as photocorrelation spectroscopy, is a method for determining the size distribution of a sample of small particles in solution by illuminating the sample with a light source (usually a laser) and measuring the time-dependent fluctuations in the intensity of the scattered light caused by Brownian motion.",
+            "rdfs:label": "DynamicLightScattering",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Dynamic Light Scattering",
+            "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:StaticLightScattering",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Static Light Scattering is a method for determining structure by measuring the total or time-averaged scattering intensity of scattered visible light as a function of angle.",
+            "rdfs:label": "StaticLightScattering",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Static Light Scattering",
+            "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:LightScatteringAssay",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A method for determining structure by measuring the change in direction or energy of scattered visible light. Light is scattered by the electrons surrounding the atomic nuclei in the sample.",
+            "rdfs:label": "LightScatteringAssay",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Light Scattering Assay",
+            "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
+            "sms:validationRules": []
+        },
         {
             "@id": "bts:Channel",
             "@type": "rdfs:Class",
@@ -5751,6 +5817,12 @@
                 },
                 {
                     "@id": "bts:3DImaging"
+                },
+                {
+                    "@id": "bts:DynamicLightScattering"
+                },
+                {
+                    "@id": "bts:StaticLightScattering"
                 }
             ],
             "sms:displayName": "assay",
@@ -6495,9006 +6567,9343 @@
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Head",
+            "@id": "bts:Rawcounts",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The head is the anterior-most division of the body.",
-            "rdfs:label": "Head",
+            "rdfs:comment": "The number or amount of something.",
+            "rdfs:label": "Rawcounts",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "head",
+            "sms:displayName": "raw counts",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Lymphnode",
+            "@id": "bts:Volume",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A bean-shaped organ surrounded by a connective tissue capsule.",
-            "rdfs:label": "Lymphnode",
+            "rdfs:comment": "The amount of three dimensional space occupied by an object or the capacity of a space or container.",
+            "rdfs:label": "Volume",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "lymph node",
+            "sms:displayName": "Volume",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Kidney",
+            "@id": "bts:Weight",
             "@type": "rdfs:Class",
-            "rdfs:comment": "One of the two bean-shaped organs located on each side of the spine in the retroperitoneum.",
-            "rdfs:label": "Kidney",
+            "rdfs:comment": "The vertical force exerted by a mass as a result of gravity.",
+            "rdfs:label": "Weight",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "kidney",
+            "sms:displayName": "Weight",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Skin",
+            "@id": "bts:PharmacokineticStudy",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The integument of an animal (as a fur-bearing mammal or a bird) separated from the body usually with its hair or feathers.",
-            "rdfs:label": "Skin",
+            "rdfs:comment": "A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.",
+            "rdfs:label": "PharmacokineticStudy",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "skin",
+            "sms:displayName": "Pharmacokinetic Study",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mammarygland",
+            "@id": "bts:GenomicVariants",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males.",
-            "rdfs:label": "Mammarygland",
+            "rdfs:comment": "Genomic alterations, including single nucleotide polymorphisms, short indels and structural variants. Use more specific term if possible, esp. if data is only of one specific subset.",
+            "rdfs:label": "GenomicVariants",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mammary gland",
+            "sms:displayName": "genomicVariants",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Nerves",
+            "@id": "bts:AlignedReads",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any of the filamentous bands of nervous tissue that connect parts of the nervous system with the other organs, conduct nervous impulses, and are made up of axons and dendrites together with protective and supportive structures.",
-            "rdfs:label": "Nerves",
+            "rdfs:comment": "Aligned reads output from alignment workflows",
+            "rdfs:label": "AlignedReads",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "nerves",
+            "sms:displayName": "AlignedReads",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Brain",
+            "@id": "bts:SomaticVariants",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The portion of the vertebrate central nervous system that constitutes the organ of thought and neural coordination.",
-            "rdfs:label": "Brain",
+            "rdfs:comment": "Called somatic variants",
+            "rdfs:label": "SomaticVariants",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "brain",
+            "sms:displayName": "SomaticVariants",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Blood",
+            "@id": "bts:AnnotatedSomaticVariants",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The fluid that circulates in the heart, arteries, capillaries, and veins of a vertebrate animal carrying nourishment and oxygen to and bringing away waste products from all parts of the body.",
-            "rdfs:label": "Blood",
+            "rdfs:comment": "Somatic variants annotated with some annotation workflow",
+            "rdfs:label": "AnnotatedSomaticVariants",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "blood",
+            "sms:displayName": "AnnotatedSomaticVariants",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Breast",
+            "@id": "bts:GermlineVariants",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The fore or ventral part of the body between the neck and the abdomen.",
-            "rdfs:label": "Breast",
+            "rdfs:comment": "Called germline variants",
+            "rdfs:label": "GermlineVariants",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "breast",
+            "sms:displayName": "GermlineVariants",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Colon",
+            "@id": "bts:AnnotatedGermlineVariants",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The part of the large intestine that extends from the cecum to the rectum.",
-            "rdfs:label": "Colon",
+            "rdfs:comment": "Germline variants annotated with some annotation workflow",
+            "rdfs:label": "AnnotatedGermlineVariants",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "colon",
+            "sms:displayName": "AnnotatedGermlineVariants",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Lung",
+            "@id": "bts:StructuralVariants",
             "@type": "rdfs:Class",
-            "rdfs:comment": "One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates.",
-            "rdfs:label": "Lung",
+            "rdfs:comment": "Specifically genomic variants data classified as structural variants, which may be derived from specialized variant calling workflows",
+            "rdfs:label": "StructuralVariants",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "lung",
+            "sms:displayName": "StructuralVariants",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Prostate",
+            "@id": "bts:Behaviorprocess",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Lobular organ the parenchyma of which has as its parts glandular acini which are continuous with the prostatic part of the urethra.",
-            "rdfs:label": "Prostate",
+            "rdfs:comment": "The action, reaction, or performance of an organism in response to external or internal stimuli.",
+            "rdfs:label": "Behaviorprocess",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "prostate",
+            "sms:displayName": "behavior process",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Pancreas",
+            "@id": "bts:Metabolomics",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon.",
-            "rdfs:label": "Pancreas",
+            "rdfs:comment": "The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism.",
+            "rdfs:label": "Metabolomics",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "pancreas",
+            "sms:displayName": "metabolomics",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Ovary",
+            "@id": "bts:Image",
             "@type": "rdfs:Class",
-            "rdfs:comment": "One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones.",
-            "rdfs:label": "Ovary",
+            "rdfs:comment": "Biological or biomedical data that has been rendered into an image.",
+            "rdfs:label": "Image",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "ovary",
+            "sms:displayName": "image",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Spleen",
+            "@id": "bts:GeneExpression",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes.",
-            "rdfs:label": "Spleen",
+            "rdfs:comment": "The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data.",
+            "rdfs:label": "GeneExpression",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "spleen",
+            "sms:displayName": "geneExpression",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bonemarrow",
+            "@id": "bts:IsoformExpression",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells.",
-            "rdfs:label": "Bonemarrow",
+            "rdfs:comment": "Expression of protien isoforms formed from alternative splicings or other post-translational modifications of a single gene through RNA splicing mechanisms.",
+            "rdfs:label": "IsoformExpression",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bone marrow",
+            "sms:displayName": "isoformExpression",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BursaOfFabricius",
+            "@id": "bts:Proteomics",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An epithelial outgrowth of lymphoid tissue in the cloaca of young birds, responsible for B-lymphocyte maturation. It undergoes atrophy and involution at six months of age.",
-            "rdfs:label": "BursaOfFabricius",
+            "rdfs:comment": "Protein and peptide identification, especially in the study of whole proteomes of organisms.",
+            "rdfs:label": "Proteomics",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Bursa Of Fabricius",
+            "sms:displayName": "proteomics",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Nose",
+            "@id": "bts:Kinomics",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract.",
-            "rdfs:label": "Nose",
+            "rdfs:comment": "Kinomics is the study of protein kinases and protein kinase signaling.",
+            "rdfs:label": "Kinomics",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "nose",
+            "sms:displayName": "kinomics",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Eye",
+            "@id": "bts:DrugScreen",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The organ of sight or vision. [ NCI ]",
-            "rdfs:label": "Eye",
+            "rdfs:comment": "Information on drug sensitivity and molecular markers of drug response",
+            "rdfs:label": "DrugScreen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Eye",
+            "sms:displayName": "drugScreen",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mesentery",
+            "@id": "bts:DrugCombinationScreen",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Mesentery",
+            "rdfs:comment": "Information on drug sensitivity of more than one compound",
+            "rdfs:label": "DrugCombinationScreen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mesentery",
+            "sms:displayName": "drugCombinationScreen",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Scalp",
+            "@id": "bts:CellularPhysiology",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Scalp",
+            "rdfs:label": "CellularPhysiology",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "scalp",
+            "sms:displayName": "cellularPhysiology",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Pelvis",
+            "@id": "bts:ChromatinActivity",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Pelvis",
+            "rdfs:comment": "Chromatin activity that allow access of condensed genomic DNA and potentially control gene expression.",
+            "rdfs:label": "ChromatinActivity",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "pelvis",
+            "sms:displayName": "chromatinActivity",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Neck",
+            "@id": "bts:SurveyData",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Neck",
+            "rdfs:comment": "A data set that contains the outcome of a survey.",
+            "rdfs:label": "SurveyData",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "neck",
+            "sms:displayName": "surveyData",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Assay"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Leg",
+            "@id": "bts:Network",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Leg",
+            "rdfs:comment": "An interconnected system of things or people.",
+            "rdfs:label": "Network",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "leg",
+            "sms:displayName": "network",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Liver",
+            "@id": "bts:Clinical",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Liver",
+            "rdfs:comment": "Data obtained through patient examination or treatment.",
+            "rdfs:label": "Clinical",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Organ"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "liver",
+            "sms:displayName": "clinical",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Axilla",
+            "@id": "bts:Immunoassay",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Axilla",
+            "rdfs:comment": "Laboratory test involving interaction of antigens with specific antibodies.",
+            "rdfs:label": "Immunoassay",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "axilla",
+            "sms:displayName": "immunoassay",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Acetabulum",
+            "@id": "bts:Electrophysiology",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Acetabulum",
+            "rdfs:comment": "Data generated from an electrophysiology assay.",
+            "rdfs:label": "Electrophysiology",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "acetabulum",
+            "sms:displayName": "electrophysiology",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Forearm",
+            "@id": "bts:Maskimage",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Forearm",
+            "rdfs:comment": "Image used as the mask for an image processing operation, such as subtraction.",
+            "rdfs:label": "Maskimage",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "forearm",
+            "sms:displayName": "mask image",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Muscle",
+            "@id": "bts:CuratedData",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Muscle",
+            "rdfs:comment": "Any file derived from or pertaining a manually or programatically curated data resource. Examples include: reference sequences, drug information databases, identifier maps\"\"",
+            "rdfs:label": "CuratedData",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "muscle",
+            "sms:displayName": "curatedData",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Finger",
+            "@id": "bts:Normalized",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Finger",
+            "rdfs:comment": "A data set that is produced as the output of a normalization data transformation.",
+            "rdfs:label": "Normalized",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataSubtype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "finger",
+            "sms:displayName": "normalized",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Thoracicspine",
+            "@id": "bts:DataMatrix",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Thoracicspine",
+            "rdfs:comment": "A file of data containing multiple values for multiple samples.",
+            "rdfs:label": "DataMatrix",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataSubtype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "thoracic spine",
+            "sms:displayName": "dataMatrix",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Groin",
+            "@id": "bts:Raw",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Anatomically also known as the inguinal part of abdomen.",
-            "rdfs:label": "Groin",
+            "rdfs:comment": "A data file produced by an instrument, or one with very little subsequent processing.",
+            "rdfs:label": "Raw",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataSubtype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "groin",
+            "sms:displayName": "raw",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Back",
+            "@id": "bts:Processed",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Anatomically also known as the dorsum.",
-            "rdfs:label": "Back",
+            "rdfs:comment": "A file of data generated from running one or more bioinformatics methods on a raw file.",
+            "rdfs:label": "Processed",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataSubtype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "back",
+            "sms:displayName": "processed",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Iliacspine",
+            "@id": "bts:Metadata",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Iliacspine",
+            "rdfs:comment": "A file of clinical, technical, or other parameters that describe a dataset.",
+            "rdfs:label": "Metadata",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataSubtype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iliac spine",
+            "sms:displayName": "metadata",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Spine",
+            "@id": "bts:Representative",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Spine",
+            "rdfs:comment": "An activity that stands as an equivalent of something or results in an equivalent; typical of, or the same as, others in a larger group of people or things.",
+            "rdfs:label": "Representative",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:DataSubtype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "spine",
+            "sms:displayName": "representative",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Shoulder",
+            "@id": "bts:Bashscript",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Shoulder",
+            "rdfs:comment": "Bash Shell Script",
+            "rdfs:label": "Bashscript",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "shoulder",
+            "sms:displayName": "bash script",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Scapula",
+            "@id": "bts:Bedgraph",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Scapula",
+            "rdfs:comment": "Holds a tab-delimited chromosome /start /end / datavalue dataset. The bedGraph format allows display of continuous-valued data in track format. This display type is useful for probability scores and transcriptome data",
+            "rdfs:label": "Bedgraph",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:BodyPart"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "scapula",
+            "sms:displayName": "bedgraph",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Schwanncellprecursor",
+            "@id": "bts:Ai",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19.",
-            "rdfs:label": "Schwanncellprecursor",
+            "rdfs:comment": "Adobe Illustrator format",
+            "rdfs:label": "Ai",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Schwann cell precursor",
+            "sms:displayName": "ai",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:B-lymphocytes",
+            "@id": "bts:Idx",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A lymphocyte of B lineage with the phenotype CD19-positive and surface immunoglobulin-positive.",
-            "rdfs:label": "B-lymphocytes",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Idx",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "B-lymphocytes",
+            "sms:displayName": "idx",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Embryonicstemcells",
+            "@id": "bts:Idat",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Embryonic stem (ES) cells are cells derived from the inner cell mass of the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent.",
-            "rdfs:label": "Embryonicstemcells",
+            "rdfs:comment": "Proprietary file format for (raw) BeadArray data used by genomewide profiling platforms from Illumina Inc. This format is output directly from the scanner and stores summary intensities for each probe-type on an array.",
+            "rdfs:label": "Idat",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Embryonic stem cells",
+            "sms:displayName": "idat",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IPSC",
+            "@id": "bts:Bam",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Induced pluripotent stem cells (iPS cells or iPSCs) are a type of pluripotent stem cell artificially derived from a non-pluripotent cell.",
-            "rdfs:label": "IPSC",
+            "rdfs:comment": "BAM format, the binary, BGZF-formatted compressed version of SAM format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s)",
+            "rdfs:label": "Bam",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iPSC",
+            "sms:displayName": "bam",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IPSC-derivedtelencephalicorganoids",
+            "@id": "bts:Bai",
             "@type": "rdfs:Class",
-            "rdfs:comment": "three-dimensional neural cultures (organoids) derived from induced pluripotent stem cells.",
-            "rdfs:label": "IPSC-derivedtelencephalicorganoids",
+            "rdfs:comment": "BAM indexing format",
+            "rdfs:label": "Bai",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iPSC-derived telencephalic organoids",
+            "sms:displayName": "bai",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GABAergicneurons",
+            "@id": "bts:Excel",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neuron that uses GABA as a vesicular neurotransmitter.",
-            "rdfs:label": "GABAergicneurons",
+            "rdfs:comment": "Microsoft Excel spreadsheet format",
+            "rdfs:label": "Excel",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GABAergic neurons",
+            "sms:displayName": "excel",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Monocytes",
+            "@id": "bts:Powerpoint",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.",
-            "rdfs:label": "Monocytes",
+            "rdfs:comment": "Microsoft Powerpoint slide format",
+            "rdfs:label": "Powerpoint",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "monocytes",
+            "sms:displayName": "powerpoint",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Microglia",
+            "@id": "bts:Tif",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system.",
-            "rdfs:label": "Microglia",
+            "rdfs:comment": "Tagged Image File Format, abbreviated TIFF or TIF, is a computer file format for storing raster graphics images",
+            "rdfs:label": "Tif",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "microglia",
+            "sms:displayName": "tif",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Macrophages",
+            "@id": "bts:Png",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.",
-            "rdfs:label": "Macrophages",
+            "rdfs:comment": "PNG is a file format for image compression",
+            "rdfs:label": "Png",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "macrophages",
+            "sms:displayName": "png",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Astrocytes",
+            "@id": "bts:Doc",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with end-feet which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier.",
-            "rdfs:label": "Astrocytes",
+            "rdfs:comment": "Microsoft Word document format",
+            "rdfs:label": "Doc",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "astrocytes",
+            "sms:displayName": "doc",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SH-SY5Y",
+            "@id": "bts:Pdf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Human neuroblastoma clonal subline of the neuroepithelioma cell line SK-N-SH that had been established in 1970 from the bone marrow biopsy of a 4-year-old girl with metastatic neuroblastoma.",
-            "rdfs:label": "SH-SY5Y",
+            "rdfs:comment": "Portable Document Format",
+            "rdfs:label": "Pdf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SH-SY5Y",
+            "sms:displayName": "pdf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GLUtamatergicneurons",
+            "@id": "bts:Hdf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Have Glutamate receptors, which are synaptic receptors located primarily on the membranes of neuronal cells. Glutamate (the conjugate base of glutamic acid) is abundant in the human body, but particularly in the nervous system and especially prominent in the human brain.",
-            "rdfs:label": "GLUtamatergicneurons",
+            "rdfs:comment": "Hierarchical Data Format (HDF) is a set of file formats (HDF4, HDF5) designed to store and organize large amounts of data",
+            "rdfs:label": "Hdf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GLUtamatergic neurons",
+            "sms:displayName": "hdf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NeuN+",
+            "@id": "bts:Fasta",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Is a neuronal nuclear antigen that is commonly used as a biomarker for neurons and NeuN immunoreactivity has been widely used to identify neurons in tissue culture to measure the neuron(positive)/glia(negative) ratio in brain regions.",
-            "rdfs:label": "NeuN+",
+            "rdfs:comment": "FASTA format is a text-based format for representing either nucleotide sequences or peptide sequences, in which nucleotides or amino acids are represented using single-letter codes",
+            "rdfs:label": "Fasta",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NeuN+",
+            "sms:displayName": "fasta",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NeuN-",
+            "@id": "bts:Fastq",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Is a neuronal nuclear antigen that is commonly used as a biomarker for neurons and NeuN immunoreactivity has been widely used to identify neurons in tissue culture to measure the neuron(positive)/glia(negative) ratio in brain regions.",
-            "rdfs:label": "NeuN-",
+            "rdfs:comment": "FASTQ format is a text-based format for storing both a biological sequence (usually nucleotide sequence) and its corresponding quality scores. Both the sequence letter and quality score are each encoded with a single ASCII character for brevity",
+            "rdfs:label": "Fastq",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NeuN-",
+            "sms:displayName": "fastq",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Epithelial",
+            "@id": "bts:Sam",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Somatic cells that cover the surface of the body and line its cavities.",
-            "rdfs:label": "Epithelial",
+            "rdfs:comment": "Sequence Alignment/Map (SAM) format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s)",
+            "rdfs:label": "Sam",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "epithelial",
+            "sms:displayName": "sam",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Epithelial-like",
+            "@id": "bts:Vcf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "In cell morphology, epithelial-like cells are polygonal in shape with more regular dimensions, and grow attached to a substrate in discrete patches.",
-            "rdfs:label": "Epithelial-like",
+            "rdfs:comment": "Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)",
+            "rdfs:label": "Vcf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "epithelial-like",
+            "sms:displayName": "vcf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fibroblast",
+            "@id": "bts:Bcf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.",
-            "rdfs:label": "Fibroblast",
+            "rdfs:comment": "BCF, the binary version of Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)",
+            "rdfs:label": "Bcf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "fibroblast",
+            "sms:displayName": "bcf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Round",
+            "@id": "bts:Maf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A phenotype observation at the level of the cell shape where the cell is round",
-            "rdfs:label": "Round",
+            "rdfs:comment": "Multiple Alignment Format (MAF) supporting alignments of whole genomes with rearrangements, directions, multiple pieces to the alignment, and so forth",
+            "rdfs:label": "Maf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "round",
+            "sms:displayName": "maf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Lymphoblast",
+            "@id": "bts:Bed",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Often referred to as a blast cell. Unlike other usages of the suffix -blast a lymphoblast is a further differentiation of a lymphocyte, T- or B-, occasioned by an antigenic stimulus. The lymphoblast usually develops by enlargement of a lymphocyte, active re-entry to the S phase of the cell cycle, mitogenesis and production of much m-RNA and ribosomes.",
-            "rdfs:label": "Lymphoblast",
+            "rdfs:comment": "Browser Extensible Data (BED) format of sequence annotation track, typically to be displayed in a genome browser",
+            "rdfs:label": "Bed",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "lymphoblast",
+            "sms:displayName": "bed",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CD8+T-Cells",
+            "@id": "bts:Chp",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.",
-            "rdfs:label": "CD8+T-Cells",
+            "rdfs:comment": "CHP file contains probe set analysis results generated from Affymetrix software",
+            "rdfs:label": "Chp",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "CD8+ T-Cells",
+            "sms:displayName": "chp",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Arachnoid",
+            "@id": "bts:Cel",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An arachnoid mater is a delicate membrane that encloses the spinal cord and brain and lies between the pia mater and dura mater.",
-            "rdfs:label": "Arachnoid",
+            "rdfs:comment": "Format of Affymetrix data file of information about (raw) expression levels of the individual probes",
+            "rdfs:label": "Cel",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "arachnoid",
+            "sms:displayName": "cel",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Meningioma",
+            "@id": "bts:Sif",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A central nervous system cancer tissue that are manifested in the central nervous system and arise from the arachnoid 'cap' cells of the arachnoid villi in the meninges.",
-            "rdfs:label": "Meningioma",
+            "rdfs:comment": "SIF (simple interaction file) Format - a network/pathway format used for instance in cytoscape",
+            "rdfs:label": "Sif",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "meningioma",
+            "sms:displayName": "sif",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Schwannoma",
+            "@id": "bts:Tsv",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves.",
-            "rdfs:label": "Schwannoma",
+            "rdfs:comment": "Tabular data represented as tab-separated values in a text file",
+            "rdfs:label": "Tsv",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "schwannoma",
+            "sms:displayName": "tsv",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Oligodendrocyte",
+            "@id": "bts:Csv",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.",
-            "rdfs:label": "Oligodendrocyte",
+            "rdfs:comment": "Tabular data represented as comma-separated values in a text file",
+            "rdfs:label": "Csv",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "oligodendrocyte",
+            "sms:displayName": "csv",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Schwann",
+            "@id": "bts:Txt",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Schwann cells are a variety of glial cell that keep peripheral nerve fibres (both myelinated and unmyelinated) alive.",
-            "rdfs:label": "Schwann",
+            "rdfs:comment": "Textual format",
+            "rdfs:label": "Txt",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "schwann",
+            "sms:displayName": "txt",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IPSC-derivedneuron",
+            "@id": "bts:Plink",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "IPSC-derivedneuron",
+            "rdfs:comment": "Any Plink file format (MAP/PED/BED/BIM/FAM)",
+            "rdfs:label": "Plink",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iPSC-derived neuron",
+            "sms:displayName": "plink",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IPSC-derivedglia",
+            "@id": "bts:Bigwig",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "IPSC-derivedglia",
+            "rdfs:comment": "bigWig format for large sequence annotation tracks that consist of a value for each sequence position",
+            "rdfs:label": "Bigwig",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iPSC-derived glia",
+            "sms:displayName": "bigwig",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IPSC-derivedastrocytes",
+            "@id": "bts:Wiggle",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "IPSC-derivedastrocytes",
+            "rdfs:comment": "Wiggle format (WIG) of a sequence annotation track that consists of a value for each sequence position",
+            "rdfs:label": "Wiggle",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iPSC-derived astrocytes",
+            "sms:displayName": "wiggle",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Monocyte-derivedmicroglia",
+            "@id": "bts:Gct",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Monocyte-derivedmicroglia",
+            "rdfs:comment": "Tab-delimited text files of GenePattern that contain a column for each sample, a row for each gene, and an expression value for each gene in each sample",
+            "rdfs:label": "Gct",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "monocyte-derived microglia",
+            "sms:displayName": "gct",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IPSC-derivedneuronalprogenitorcell",
+            "@id": "bts:Bgzip",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "IPSC-derivedneuronalprogenitorcell",
+            "rdfs:comment": "Blocked GNU Zip format",
+            "rdfs:label": "Bgzip",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "iPSC-derived neuronal progenitor cell",
+            "sms:displayName": "bgzip",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CD138+",
+            "@id": "bts:Zip",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "CD138+",
+            "rdfs:comment": "zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification",
+            "rdfs:label": "Zip",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "CD138+",
+            "sms:displayName": "zip",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CNON",
+            "@id": "bts:Seg",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Cultured Neuronal cells derived from Olfactory Neuroepithelium",
-            "rdfs:label": "CNON",
+            "rdfs:comment": "SEG file (segmented data; .seg or .cbs) is a tab-delimited text file that lists loci and associated numeric values",
+            "rdfs:label": "Seg",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "CNON",
+            "sms:displayName": "seg",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Teratoma",
+            "@id": "bts:Html",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach",
-            "rdfs:label": "Teratoma",
+            "rdfs:comment": "HTML format",
+            "rdfs:label": "Html",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "teratoma",
+            "sms:displayName": "html",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CulturedMullerglia",
+            "@id": "bts:Mov",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. [ http://www.ncbi.nlm.nih.gov/pubmed/21911394 GOC : NV ]",
-            "rdfs:label": "CulturedMullerglia",
+            "rdfs:comment": "A video file format with the .mov extension",
+            "rdfs:label": "Mov",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cultured Muller glia",
+            "sms:displayName": "mov",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DRG/nerverootneurospherecell",
+            "@id": "bts:Hyperlink",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Dorsal root ganglia/nerve root neurosphere cells (DNSCs) are cultured from embryonic DRGs/nerve roots and have been used in in vitro sphere assays to study the origin of para-spinal neurofibromas. See reference PMC4254535",
-            "rdfs:label": "DRG/nerverootneurospherecell",
+            "rdfs:comment": "A reference (link) from some point in one hypertext document to another document, another place in the same document, or a website.",
+            "rdfs:label": "Hyperlink",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CellType"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "DRG/nerve root neurosphere cell",
+            "sms:displayName": "hyperlink",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Neurofibromatosistype1",
+            "@id": "bts:Svs",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(NF1) - A disease characterized by patches of skin pigmentation (cafe-au-lait spots), Lisch nodules of the iris, tumors in the peripheral nervous system and fibromatous skin tumors. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors.",
-            "rdfs:label": "Neurofibromatosistype1",
+            "rdfs:comment": "A single-file pyramidal tiled TIFF, with non-standard metadata and compression.",
+            "rdfs:label": "Svs",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Diagnosis"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Neurofibromatosis type 1",
+            "sms:displayName": "svs",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Neurofibromatosistype2",
+            "@id": "bts:Md",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(NF2) - Genetic disorder characterized by bilateral vestibular schwannomas (formerly called acoustic neuromas), schwannomas of other cranial and peripheral nerves, meningiomas, and ependymomas. It is inherited in an autosomal dominant fashion with full penetrance.",
-            "rdfs:label": "Neurofibromatosistype2",
+            "rdfs:comment": "Markdown (MD) is a lightweight markup language with plain text formatting syntax",
+            "rdfs:label": "Md",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Diagnosis"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Neurofibromatosis type 2",
+            "sms:displayName": "md",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Schwannomatosis",
+            "@id": "bts:Flagstat",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A rare genetic disorder characterized by the presence of multiple schwannomas.",
-            "rdfs:label": "Schwannomatosis",
+            "rdfs:comment": "Output of samtools flagstat tool",
+            "rdfs:label": "Flagstat",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Diagnosis"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Schwannomatosis",
+            "sms:displayName": "flagstat",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NotApplicable",
+            "@id": "bts:Gtf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An NF diagnosis (e.g. NF1, NF2, or Schwannomatosis) does not apply here.",
-            "rdfs:label": "NotApplicable",
+            "rdfs:comment": "Gene transfer format (GTF) is a file format used to hold information about gene structure",
+            "rdfs:label": "Gtf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Diagnosis"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Not Applicable",
+            "sms:displayName": "gtf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SporadicSchwannoma",
+            "@id": "bts:Raw",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A",
-            "rdfs:label": "SporadicSchwannoma",
+            "rdfs:comment": "Proprietary file format for mass spectrometry data from Thermo Scientific",
+            "rdfs:label": "Raw",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Diagnosis"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Sporadic Schwannoma",
+            "sms:displayName": "raw",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Cancer",
+            "@id": "bts:Msf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Cancer",
+            "rdfs:comment": "Proprietary mass-spectrometry format of Thermo Scientific's ProteomeDiscoverer software",
+            "rdfs:label": "Msf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cancer",
+            "sms:displayName": "msf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Neuro",
+            "@id": "bts:Rmd",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Neuro",
+            "rdfs:comment": "markdown document specific to r analyses",
+            "rdfs:label": "Rmd",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "neuro",
+            "sms:displayName": "rmd",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Neurofibromatosis",
+            "@id": "bts:BednarrowPeak",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Neurofibromatosis",
+            "rdfs:comment": "This format is used to provide called peaks of signal enrichment based on pooled, normalized (interpreted) data. It is a BED6+4 format.",
+            "rdfs:label": "BednarrowPeak",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "neurofibromatosis",
+            "sms:displayName": "bed narrowPeak",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:-/-",
+            "@id": "bts:BedbroadPeak",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Homozygous deletion or mutation of NF1.",
-            "rdfs:label": "-/-",
+            "rdfs:comment": "This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data. It is a BED 6+3 format.",
+            "rdfs:label": "BedbroadPeak",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf1Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "-/-",
+            "sms:displayName": "bed broadPeak",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:+/-",
+            "@id": "bts:BedgappedPeak",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Heterozygous deletion or mutation",
-            "rdfs:label": "+/-",
+            "rdfs:comment": "This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data where the regions may be spliced or incorporate gaps in the genomic sequence. It is a BED12+3 format.",
+            "rdfs:label": "BedgappedPeak",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf1Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "+/-",
+            "sms:displayName": "bed gappedPeak",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:+/+",
+            "@id": "bts:Avi",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Homozygous wildtype",
-            "rdfs:label": "+/+",
+            "rdfs:comment": "AVI files can contain both audio and video data in a file container that allows synchronous audio-with-video playback.",
+            "rdfs:label": "Avi",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf1Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "+/+",
+            "sms:displayName": "avi",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Unknown",
+            "@id": "bts:Pzfx",
             "@type": "rdfs:Class",
-            "rdfs:comment": "unknown",
-            "rdfs:label": "Unknown",
+            "rdfs:comment": "A PZFX file is a Prism project created by GraphPad Prism, a scientific application used to analyze and graph data. It contains project data including graphs and layouts, notes, and tables.",
+            "rdfs:label": "Pzfx",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf1Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Unknown",
+            "sms:displayName": "pzfx",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:-/-",
+            "@id": "bts:Fig",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Homozygous deletion or mutation of NF2.",
-            "rdfs:label": "-/-",
+            "rdfs:comment": "Line drawing saved in the Xfig format; stored as a vector image that may include lines, shapes, arcs, splines, arrows, and text objects; may also include images, colors, and patterns.",
+            "rdfs:label": "Fig",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "-/-",
+            "sms:displayName": "fig",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:+/-",
+            "@id": "bts:Xml",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Heterozygous deletion or mutation",
-            "rdfs:label": "+/-",
+            "rdfs:comment": "eXtensible Markup Language (XML) format.",
+            "rdfs:label": "Xml",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "+/-",
+            "sms:displayName": "xml",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:+/+",
+            "@id": "bts:Tar",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Homozygous wild type",
-            "rdfs:label": "+/+",
+            "rdfs:comment": "tape archive",
+            "rdfs:label": "Tar",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "+/+",
+            "sms:displayName": "tar",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Unknown",
+            "@id": "bts:Rscript",
             "@type": "rdfs:Class",
-            "rdfs:comment": "unknown",
-            "rdfs:label": "Unknown",
+            "rdfs:comment": "R script with expected extension “.R”.",
+            "rdfs:label": "Rscript",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Unknown",
+            "sms:displayName": "R script",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:C57BL/6J",
+            "@id": "bts:Abf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "C57BL/6 is the most widely used inbred strain. It is commonly used as a general purpose strain and background strain for the generation of congenics carrying both spontaneous and induced mutations.",
-            "rdfs:label": "C57BL/6J",
+            "rdfs:comment": "The Axon Binary File format (ABF) was created for the storage of binary experimental data.",
+            "rdfs:label": "Abf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "C57BL/6J",
+            "sms:displayName": "abf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NODscidgamma",
+            "@id": "bts:Bpm",
             "@type": "rdfs:Class",
-            "rdfs:comment": "These mice are most often referred to using their branded name NSG™ and are extremely immunodeficient.",
-            "rdfs:label": "NODscidgamma",
+            "rdfs:comment": "A beaded pool manifest. Describe the SNP or probe content on a BeadChip or in an assay pool.",
+            "rdfs:label": "Bpm",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NOD scid gamma",
+            "sms:displayName": "bpm",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NRG",
+            "@id": "bts:Dat",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Extremely immunodeficient mice with a targeted knockout mutation in recombination activating gene 1 (Rag1) and a complete null allele of the IL2 receptor common gamma chain.",
-            "rdfs:label": "NRG",
+            "rdfs:comment": "Format of Affymetrix data file of raw image data.",
+            "rdfs:label": "Dat",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NRG",
+            "sms:displayName": "dat",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:B6;129S2-Trp53tm1TyjNf1tm1Tyj/J",
+            "@id": "bts:Jpg",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "B6;129S2-Trp53tm1TyjNf1tm1Tyj/J",
+            "rdfs:comment": "Joint Picture Group file format for lossy graphics file.",
+            "rdfs:label": "Jpg",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "B6;129S2-Trp53tm1Tyj Nf1tm1Tyj/J",
+            "sms:displayName": "jpg",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:B6;129-Trp53tm1TyjNf1tm1TyjSuz12Gt(Betageo)1Khe/KcichJ",
+            "@id": "bts:Locs",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "B6;129-Trp53tm1TyjNf1tm1TyjSuz12Gt(Betageo)1Khe/KcichJ",
+            "rdfs:comment": "Illumina iScan bead location file.",
+            "rdfs:label": "Locs",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "B6;129-Trp53tm1Tyj Nf1tm1Tyj Suz12Gt(Betageo)1Khe/KcichJ",
+            "sms:displayName": "locs",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:B6.129S2-Nf1tm1Tyj/J",
+            "@id": "bts:Sentrixdescriptorfile",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "B6.129S2-Nf1tm1Tyj/J",
+            "rdfs:comment": "A BeadScan specific file needed to perform scan setting checks for different array formats and assay type.",
+            "rdfs:label": "Sentrixdescriptorfile",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
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             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "B6.129S2-Nf1tm1Tyj/J",
+            "sms:displayName": "Sentrix descriptor file",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:B6.129S1-Nf1tm1Cbr/J",
+            "@id": "bts:Pythonscript",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "B6.129S1-Nf1tm1Cbr/J",
+            "rdfs:comment": "Python script with expected extension “.py”.",
+            "rdfs:label": "Pythonscript",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
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             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "B6.129S1-Nf1tm1Cbr/J",
+            "sms:displayName": "Python script",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:B6.129(Cg)-Nf1tm1Par/J",
+            "@id": "bts:MATLABscript",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "B6.129(Cg)-Nf1tm1Par/J",
+            "rdfs:comment": "A MATLAB script file with expected extension “.m”. Note that files with a “.mat” extension contains MATLAB formatted data.",
+            "rdfs:label": "MATLABscript",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
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             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "B6.129(Cg)-Nf1tm1Par/J",
+            "sms:displayName": "MATLAB script",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HiPSC-SCP",
+            "@id": "bts:MATLABdata",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Schwann cell precursor iPSCs",
-            "rdfs:label": "HiPSC-SCP",
+            "rdfs:comment": "A MATLAB formatted data file with expected extension “.mat”.",
+            "rdfs:label": "MATLABdata",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hiPSC-SCP",
+            "sms:displayName": "MATLAB data",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HiPSC",
+            "@id": "bts:Sav",
             "@type": "rdfs:Class",
-            "rdfs:comment": "human iPSCs",
-            "rdfs:label": "HiPSC",
+            "rdfs:comment": "The SPSS Statistics File Format is a proprietary binary format, developed and maintained as the native format for the SPSS statistical software application.",
+            "rdfs:label": "Sav",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hiPSC",
+            "sms:displayName": "sav",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JHU2-103-CL",
+            "@id": "bts:Gzip",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An MPNST cell line derived from JHU NF1 Biobank tumor specimen JHU 2-103.",
-            "rdfs:label": "JHU2-103-CL",
+            "rdfs:comment": "GZipped format",
+            "rdfs:label": "Gzip",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JHU 2-103-CL",
+            "sms:displayName": "gzip",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JHU2-002-CL",
+            "@id": "bts:Sdf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An MPNST cell line derived from JHU NF1 Biobank tumor specimen JHU 2-002.",
-            "rdfs:label": "JHU2-002-CL",
+            "rdfs:comment": "SDF is one of a family of chemical-data file formats developed by MDL Information Systems; it is intended especially for structural information.",
+            "rdfs:label": "Sdf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JHU 2-002-CL",
+            "sms:displayName": "sdf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JHU2-079-CL",
+            "@id": "bts:RData",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An MPNST cell line derived from JHU NF1 Biobank tumor specimen JHU 2-079.",
-            "rdfs:label": "JHU2-079-CL",
+            "rdfs:comment": "The RData format (usually with extension .rdata or .rda) is a format designed for use with R, a system for statistical computation and related graphics, for storing a complete R workspace or selected 'objects' from a workspace in a form that can be loaded back by R.",
+            "rdfs:label": "RData",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JHU 2-079-CL",
+            "sms:displayName": "RData",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JHU2-103-PDX",
+            "@id": "bts:Hic",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A PDX model derived from JHU NF1 Biobank tumor specimen JHU 2-103.",
-            "rdfs:label": "JHU2-103-PDX",
+            "rdfs:comment": "Hi-C contact matrix file",
+            "rdfs:label": "Hic",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JHU 2-103-PDX",
+            "sms:displayName": "hic",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JHU2-002-PDX",
+            "@id": "bts:Ab1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A PDX model derived from JHU NF1 Biobank tumor specimen JHU 2-002.",
-            "rdfs:label": "JHU2-002-PDX",
+            "rdfs:comment": "TAB1 binary format of raw DNA sequence reads (output of Applied Biosystems' sequencing analysis software). Contains an electropherogram and the DNA base sequence.",
+            "rdfs:label": "Ab1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JHU 2-002-PDX",
+            "sms:displayName": "ab1",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JHU2-079-PDX",
+            "@id": "bts:7z",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A PDX model derived from JHU NF1 Biobank tumor specimen JHU 2-079.",
-            "rdfs:label": "JHU2-079-PDX",
+            "rdfs:comment": "A compressed archive file format that supports several different data compression, encryption and pre-processing filters.",
+            "rdfs:label": "7z",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JHU 2-079-PDX",
+            "sms:displayName": "7z",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF05.5",
+            "@id": "bts:Gff3",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTNF1ipNF05.5",
+            "rdfs:comment": "Generic Feature Format version 3 (GFF3) of sequence features.",
+            "rdfs:label": "Gff3",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF05.5",
+            "sms:displayName": "gff3",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF05.5(Mixedclones)",
+            "@id": "bts:Json",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTNF1ipNF05.5(Mixedclones)",
+            "rdfs:comment": "JavaScript Object Notation format; a lightweight, text-based format to represent tree-structured data using key-value pairs.",
+            "rdfs:label": "Json",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF05.5 (Mixed clones)",
+            "sms:displayName": "json",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipn06.2A",
+            "@id": "bts:Sqlite",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTNF1ipn06.2A",
+            "rdfs:comment": "Data format used by the SQLite database.",
+            "rdfs:label": "Sqlite",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipn06.2 A",
+            "sms:displayName": "sqlite",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF95.11bC/T",
+            "@id": "bts:Svg",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTNF1ipNF95.11bC/T",
+            "rdfs:comment": "Scalable Vector Graphics (SVG) is an XML-based vector image format for two-dimensional graphics with support for interactivity and animation.",
+            "rdfs:label": "Svg",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF95.11b C/T",
+            "sms:displayName": "svg",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF95.6",
+            "@id": "bts:Sra",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTNF1ipNF95.6",
+            "rdfs:comment": "SRA archive format (SRA) is the archive format used for input to the NCBI Sequence Read Archive.",
+            "rdfs:label": "Sra",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF95.6",
+            "sms:displayName": "sra",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTSCipn02.8",
+            "@id": "bts:Recal",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTSCipn02.8",
+            "rdfs:comment": ".recal file from GATK VQSR",
+            "rdfs:label": "Recal",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT SC ipn02.8",
+            "sms:displayName": "recal",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipnNF95.11c",
+            "@id": "bts:Tranches",
             "@type": "rdfs:Class",
-            "rdfs:comment": "plexiform neurofibroma cell line",
-            "rdfs:label": "HTERTNF1ipnNF95.11c",
+            "rdfs:comment": ".tranches file from GATK VQSR",
+            "rdfs:label": "Tranches",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipnNF95.11c",
+            "sms:displayName": "tranches",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF95.11bC",
+            "@id": "bts:Mtx",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1ipNF95.11bC",
+            "rdfs:comment": "Matrix Market Exchange Format",
+            "rdfs:label": "Mtx",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF95.11b C",
+            "sms:displayName": "mtx",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipnNF09.4",
+            "@id": "bts:TagAlign",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1ipnNF09.4",
+            "rdfs:comment": "Tag Alignment provides genomic mapping of short sequence tags.",
+            "rdfs:label": "TagAlign",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipnNF09.4",
+            "sms:displayName": "tagAlign",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF04.4",
+            "@id": "bts:Dup",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1ipNF04.4",
+            "rdfs:comment": "output of the Picard MarkDuplicates tool.",
+            "rdfs:label": "Dup",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF04.4",
+            "sms:displayName": "dup",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1sipnNF95.12B",
+            "@id": "bts:DICOM",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1sipnNF95.12B",
+            "rdfs:comment": "A comprehensive set of standards for communications between medical imaging devices, including handling, storing and transmitting information in medical imaging. It includes a file format definition and a network communication protocol.",
+            "rdfs:label": "DICOM",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 sipnNF95.12B",
+            "sms:displayName": "DICOM",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF00.6",
+            "@id": "bts:Czi",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1ipNF00.6",
+            "rdfs:comment": "microscopy imaging file format that saves multidimensional images such as time lapse, Z-stacks, multiposition experiments and virtual slides, combined with relevant meta information",
+            "rdfs:label": "Czi",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF00.6",
+            "sms:displayName": "czi",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipNF03.3",
+            "@id": "bts:MzML",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1ipNF03.3",
+            "rdfs:comment": "mzML format for raw spectrometer output data, standardised by HUPO PSI MSS.",
+            "rdfs:label": "MzML",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipNF03.3",
+            "sms:displayName": "mzML",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTNF1ipn02.32λ",
+            "@id": "bts:SPAR",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTNF1ipn02.32λ",
+            "rdfs:comment": "Phillips MRS Header File",
+            "rdfs:label": "SPAR",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT NF1 ipn02.3 2λ",
+            "sms:displayName": "SPAR",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HTERTSCipn02.8",
+            "@id": "bts:SDAT",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "HTERTSCipn02.8",
+            "rdfs:comment": "Phillips MRS Data File",
+            "rdfs:label": "SDAT",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hTERT SC ipn02.8",
+            "sms:displayName": "SDAT",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SZ-NF1",
+            "@id": "bts:Nii",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SZ-NF1",
+            "rdfs:comment": "NIfTI-1 can store image data from any modality such as PET, MRI, CT, EEG that produces regularly sampled 1-5D rasters.",
+            "rdfs:label": "Nii",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SZ-NF1",
+            "sms:displayName": "nii",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SZ-NF2",
+            "@id": "bts:PAR",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SZ-NF2",
+            "rdfs:comment": "This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).",
+            "rdfs:label": "PAR",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SZ-NF2",
+            "sms:displayName": "PAR",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SZ-NF4",
+            "@id": "bts:REC",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SZ-NF4",
+            "rdfs:comment": "This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).",
+            "rdfs:label": "REC",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SZ-NF4",
+            "sms:displayName": "REC",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NF1",
+            "@id": "bts:Hdr",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NF1",
+            "rdfs:comment": "MRI Header file, as in the NIFTI-1 Analyze 7.5 format",
+            "rdfs:label": "Hdr",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NF1",
+            "sms:displayName": "hdr",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Lis42NF11N",
+            "@id": "bts:Img",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Lis42NF11N",
+            "rdfs:comment": "MRI Data file, as in the NIFTI-1 Analyze 7.5 format",
+            "rdfs:label": "Img",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Lis42_NF1_1N",
+            "sms:displayName": "img",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Lis47NF12N",
+            "@id": "bts:Sf",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Lis47NF12N",
+            "rdfs:comment": "Salmon’s main output is its quantification file. This file is a plain-text, tab-separated file with a single header line (which names all of the columns).",
+            "rdfs:label": "Sf",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Lis47_NF1_2N",
+            "sms:displayName": "sf",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ST88-14",
+            "@id": "bts:Tom",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "ST88-14",
+            "rdfs:comment": "The .tom format is a specialized 3D image export format from the Vectra medical imaging systems that can optionally preserve trimmings and/or landmarks.",
+            "rdfs:label": "Tom",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:FileFormat"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "ST88-14",
+            "sms:displayName": "tom",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SNF96.2",
+            "@id": "bts:Genesymbol",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SNF96.2",
+            "rdfs:comment": "A unique gene name approved by an organism specific nomenclature committee.",
+            "rdfs:label": "Genesymbol",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedDataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sNF96.2",
+            "sms:displayName": "gene symbol",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SNF02.2",
+            "@id": "bts:Clinicaldata",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SNF02.2",
+            "rdfs:comment": "Data obtained through patient examination or treatment.",
+            "rdfs:label": "Clinicaldata",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedDataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sNF02.2",
+            "sms:displayName": "clinical data",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SNF94.3",
+            "@id": "bts:Genefunction",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SNF94.3",
+            "rdfs:comment": "A term that expresses the function of a gene product.",
+            "rdfs:label": "Genefunction",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedDataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sNF94.3",
+            "sms:displayName": "gene function",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GM11602",
+            "@id": "bts:Chemicaldescriptor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "GM11602",
+            "rdfs:comment": "A chemical descriptor is a data item (quantity or value) about a chemical entity that conforms to a specification for how it is calculated, measured or recorded.",
+            "rdfs:label": "Chemicaldescriptor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedDataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GM11602",
+            "sms:displayName": "chemical descriptor",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GM11601",
+            "@id": "bts:Individual",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "GM11601",
+            "rdfs:comment": "Metadata describing properties of individuals (human or animal) represented in the study.",
+            "rdfs:label": "Individual",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:MetadataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GM11601",
+            "sms:displayName": "individual",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:KCL024",
+            "@id": "bts:Biospecimen",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "KCL024",
+            "rdfs:comment": "Metadata describing properties of specimens collected and/or analyzed in the study.",
+            "rdfs:label": "Biospecimen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:MetadataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "KCL024",
+            "sms:displayName": "biospecimen",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:KCL025",
+            "@id": "bts:Assay",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "KCL025",
+            "rdfs:comment": "Metadata describing properties of an assay conducted in the study.",
+            "rdfs:label": "Assay",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:MetadataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "KCL025",
+            "sms:displayName": "assay",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:5PNFTDiPSsvPM6",
+            "@id": "bts:Datadictionary",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "5PNFTDiPSsvPM6",
+            "rdfs:comment": "Metadata describing terms or variables that appear in another file.",
+            "rdfs:label": "Datadictionary",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:MetadataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "5PNF_TDiPSsv_PM_6",
+            "sms:displayName": "data dictionary",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:5PNFTDiPSsvMM4",
+            "@id": "bts:Manifest",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "5PNFTDiPSsvMM4",
+            "rdfs:comment": "Metadata describing a list of files and the annotations terms associated with them.",
+            "rdfs:label": "Manifest",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:MetadataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "5PNF_TDiPSsv_MM_4",
+            "sms:displayName": "manifest",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:7PNFSiPSrvPM12",
+            "@id": "bts:Protocol",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "7PNFSiPSrvPM12",
+            "rdfs:comment": "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",
+            "rdfs:label": "Protocol",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:MetadataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "7PNF_SiPSrv_PM_12",
+            "sms:displayName": "protocol",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:6PNFSiPSrvPM2",
+            "@id": "bts:GRCh38",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "6PNFSiPSrvPM2",
+            "rdfs:comment": "Genome Reference Consortium Human Build 38",
+            "rdfs:label": "GRCh38",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ReferenceSet"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "6PNF_SiPSrv_PM_2",
+            "sms:displayName": "GRCh38",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:3PNFSiPSsvMM11",
+            "@id": "bts:GRCh37",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "3PNFSiPSsvMM11",
-            "rdfs:subClassOf": [
+            "rdfs:comment": "Genome Reference Consortium Human Build 37",
+            "rdfs:label": "GRCh37",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ReferenceSet"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "3PNF_SiPSsv_MM_11",
+            "sms:displayName": "GRCh37",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:3PNFFiPSsvPM2",
+            "@id": "bts:MMUL1.0",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "3PNFFiPSsvPM2",
+            "rdfs:comment": "Ensembl preliminary assembly Macaca mulatta",
+            "rdfs:label": "MMUL1.0",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ReferenceSet"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "3PNF_FiPSsv_PM_2",
+            "sms:displayName": "MMUL1.0",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NCC-MPNST5-C1",
+            "@id": "bts:HRC",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NCC-MPNST5-C1",
+            "rdfs:comment": "Human haplotype reference panel",
+            "rdfs:label": "HRC",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ReferenceSet"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NCC-MPNST5-C1",
+            "sms:displayName": "HRC",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NCC-MPNST3-C1",
+            "@id": "bts:ExperimentalData",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NCC-MPNST3-C1",
+            "rdfs:comment": "Any file derived from or pertaining to a scientific experiment. experimentalData annotations should be applied, possibly disease-related",
+            "rdfs:label": "ExperimentalData",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NCC-MPNST3-C1",
+            "sms:displayName": "experimentalData",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NCC-MPNST4-C1",
+            "@id": "bts:Result",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NCC-MPNST4-C1",
+            "rdfs:comment": "Any file that reports data results. Examples include figures, presentations, analysis, etc.",
+            "rdfs:label": "Result",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NCC-MPNST4-C1",
+            "sms:displayName": "result",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NCC-MPNST3-X2-C1",
+            "@id": "bts:Tool",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NCC-MPNST3-X2-C1",
+            "rdfs:comment": "Any file or link that represents a tool, model, or algorithm; the tool annotations could be applied",
+            "rdfs:label": "Tool",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NCC-MPNST3-X2-C1",
+            "sms:displayName": "tool",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NCC-MPNST2-C1",
+            "@id": "bts:Workflowreport",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NCC-MPNST2-C1",
+            "rdfs:comment": "Workflow-generated reports of analysis of primary data, usually created programmatically at completion of workflow step.",
+            "rdfs:label": "Workflowreport",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NCC-MPNST2-C1",
+            "sms:displayName": "workflow report",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:STS-26T",
+            "@id": "bts:Report",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "STS-26T",
+            "rdfs:comment": "a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).",
+            "rdfs:label": "Report",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "STS-26T",
+            "sms:displayName": "report",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:YST-1",
+            "@id": "bts:Metadata",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "YST-1",
+            "rdfs:comment": "Data about data; information that describes another set of data.",
+            "rdfs:label": "Metadata",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "YST-1",
+            "sms:displayName": "metadata",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:90-8",
+            "@id": "bts:Protocol",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "90-8",
+            "rdfs:comment": "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",
+            "rdfs:label": "Protocol",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ResourceType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "90-8",
+            "sms:displayName": "protocol",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:S520",
+            "@id": "bts:CuratedDataType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "S520",
+            "rdfs:comment": "The type of information being curated.",
+            "rdfs:label": "CuratedDataType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "S520",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:S462",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "S462",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:Referencesequence"
+                },
+                {
+                    "@id": "bts:Genesymbol"
+                },
+                {
+                    "@id": "bts:Clinicaldata"
+                },
+                {
+                    "@id": "bts:Genefunction"
+                },
+                {
+                    "@id": "bts:Chemicaldescriptor"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "S462",
-            "sms:required": "sms:false",
+            "sms:displayName": "curatedDataType",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:S462.TY",
+            "@id": "bts:ReferenceSet",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "S462.TY",
+            "rdfs:comment": "A set of references (e.g., canonical assembled contigs) which defines a common coordinate space for comparing reference-aligned experimental data.",
+            "rdfs:label": "ReferenceSet",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "S462.TY",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:T265",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "T265",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:GRCh38"
+                },
+                {
+                    "@id": "bts:GRCh37"
+                },
+                {
+                    "@id": "bts:MMUL1.0"
+                },
+                {
+                    "@id": "bts:HRC"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "T265",
-            "sms:required": "sms:false",
+            "sms:displayName": "referenceSet",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sc93.1",
+            "@id": "bts:Referencesequence",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Cell line generated by Ray Mattingly's lab.",
-            "rdfs:label": "Sc93.1",
+            "rdfs:comment": "Syntactic sequences that has a role as reference of an annotation.",
+            "rdfs:label": "Referencesequence",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:CuratedDataType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sc93.1",
+            "sms:displayName": "reference sequence",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fb93.1",
+            "@id": "bts:DataSubtype",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Cell line generated by Ray Mattingly's lab.",
-            "rdfs:label": "Fb93.1",
+            "rdfs:comment": "Further qualification of dataType, which may be used to indicate the state of processing of the data, aggregation of the data, or presence of metadata.",
+            "rdfs:label": "DataSubtype",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Fb93.1",
-            "sms:required": "sms:false",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Normalized"
+                },
+                {
+                    "@id": "bts:DataMatrix"
+                },
+                {
+                    "@id": "bts:Raw"
+                },
+                {
+                    "@id": "bts:Processed"
+                },
+                {
+                    "@id": "bts:Metadata"
+                },
+                {
+                    "@id": "bts:Representative"
+                }
+            ],
+            "sms:displayName": "dataSubtype",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JH-2-002-CL",
+            "@id": "bts:MetadataType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Cell line derived from JHU biobank individual",
-            "rdfs:label": "JH-2-002-CL",
+            "rdfs:comment": "For files of dataSubtype: metadata, a description of the type of metadata in the file.",
+            "rdfs:label": "MetadataType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JH-2-002-CL",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Individual"
+                },
+                {
+                    "@id": "bts:Biospecimen"
+                },
+                {
+                    "@id": "bts:Assay"
+                },
+                {
+                    "@id": "bts:Datadictionary"
+                },
+                {
+                    "@id": "bts:Manifest"
+                },
+                {
+                    "@id": "bts:Protocol"
+                }
+            ],
+            "sms:displayName": "metadataType",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JH-2-079-CL",
+            "@id": "bts:DataType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Cell line derived from JHU biobank individual",
-            "rdfs:label": "JH-2-079-CL",
+            "rdfs:comment": "A type of experimental, clinical, or other data. This typically refers to a high-level data type that can be related to an assay type. For example, a file of dataType `genomicVariants` might have an assay value of `whole genome sequencing`.",
+            "rdfs:label": "DataType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "JH-2-079-CL",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:JH-2-103-CL",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Cell line derived from JHU biobank individual",
-            "rdfs:label": "JH-2-103-CL",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:Volume"
+                },
+                {
+                    "@id": "bts:Weight"
+                },
+                {
+                    "@id": "bts:PharmacokineticStudy"
+                },
+                {
+                    "@id": "bts:GenomicVariants"
+                },
+                {
+                    "@id": "bts:Behaviorprocess"
+                },
+                {
+                    "@id": "bts:Metabolomics"
+                },
+                {
+                    "@id": "bts:Image"
+                },
+                {
+                    "@id": "bts:GeneExpression"
+                },
+                {
+                    "@id": "bts:IsoformExpression"
+                },
+                {
+                    "@id": "bts:Proteomics"
+                },
+                {
+                    "@id": "bts:Kinomics"
+                },
+                {
+                    "@id": "bts:DrugScreen"
+                },
+                {
+                    "@id": "bts:DrugCombinationScreen"
+                },
+                {
+                    "@id": "bts:CellularPhysiology"
+                },
+                {
+                    "@id": "bts:ChromatinActivity"
+                },
+                {
+                    "@id": "bts:SurveyData"
+                },
+                {
+                    "@id": "bts:Network"
+                },
+                {
+                    "@id": "bts:Clinical"
+                },
+                {
+                    "@id": "bts:Immunoassay"
+                },
+                {
+                    "@id": "bts:Electrophysiology"
+                },
+                {
+                    "@id": "bts:Rawcounts"
+                },
+                {
+                    "@id": "bts:Maskimage"
+                },
+                {
+                    "@id": "bts:AlignedReads"
+                },
+                {
+                    "@id": "bts:SomaticVariants"
+                },
+                {
+                    "@id": "bts:AnnotatedSomaticVariants"
+                },
+                {
+                    "@id": "bts:StructuralVariants"
+                },
+                {
+                    "@id": "bts:GermlineVariants"
+                },
+                {
+                    "@id": "bts:AnnotatedGermlineVariants"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "JH-2-103-CL",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:IcNF00.10a",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF00.10a).",
-            "rdfs:label": "IcNF00.10a",
-            "rdfs:subClassOf": [
+            "sms:displayName": "dataType",
+            "sms:required": "sms:true",
+            "sms:requiresDependency": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:DataSubtype"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "icNF00.10a",
-            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CNF00.10a",
+            "@id": "bts:ExpressionUnit",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF00.10a).",
-            "rdfs:label": "CNF00.10a",
+            "rdfs:comment": "Measure used for transcript expression quantification",
+            "rdfs:label": "ExpressionUnit",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cNF00.10a",
-            "sms:required": "sms:false",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:TPM"
+                },
+                {
+                    "@id": "bts:RPKM"
+                },
+                {
+                    "@id": "bts:FPKM"
+                },
+                {
+                    "@id": "bts:Counts"
+                },
+                {
+                    "@id": "bts:Other"
+                }
+            ],
+            "sms:displayName": "expressionUnit",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IcNF97.2a",
+            "@id": "bts:FailedQC",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF97.2a).",
-            "rdfs:label": "IcNF97.2a",
+            "rdfs:comment": "Whether the sample or data failed QC checks (Yes; No)",
+            "rdfs:label": "FailedQC",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "icNF97.2a",
-            "sms:required": "sms:false",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Yes"
+                },
+                {
+                    "@id": "bts:No"
+                }
+            ],
+            "sms:displayName": "failedQC",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CNF97.2a",
+            "@id": "bts:Filename",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF97.2a).",
-            "rdfs:label": "CNF97.2a",
+            "rdfs:comment": "The name of the file.",
+            "rdfs:label": "Filename",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:NF"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cNF97.2a",
-            "sms:required": "sms:false",
+            "sms:displayName": "Filename",
+            "sms:required": "sms:true",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:EntityId"
+                },
+                {
+                    "@id": "bts:FileFormat"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IcNF97.2b",
+            "@id": "bts:ProgrammingLanguage",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF97.2b).",
-            "rdfs:label": "IcNF97.2b",
+            "rdfs:comment": "A computer programming language",
+            "rdfs:label": "ProgrammingLanguage",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "icNF97.2b",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Python"
+                },
+                {
+                    "@id": "bts:R"
+                },
+                {
+                    "@id": "bts:MATLAB"
+                },
+                {
+                    "@id": "bts:Java"
+                },
+                {
+                    "@id": "bts:C"
+                },
+                {
+                    "@id": "bts:C++"
+                },
+                {
+                    "@id": "bts:C#"
+                },
+                {
+                    "@id": "bts:Javascript"
+                },
+                {
+                    "@id": "bts:Bash"
+                }
+            ],
+            "sms:displayName": "programmingLanguage",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CNF97.2b",
+            "@id": "bts:RuntimePlatform",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF97.2b).",
-            "rdfs:label": "CNF97.2b",
+            "rdfs:comment": "Runtime platform or script interpreter dependencies (e.g. Java v1, Python 2.3).",
+            "rdfs:label": "RuntimePlatform",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cNF97.2b",
+            "sms:displayName": "runtimePlatform",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IcNF98.4d",
+            "@id": "bts:Documentation",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF98.4d).",
-            "rdfs:label": "IcNF98.4d",
+            "rdfs:comment": "URL to any documentation describing the resource and its use.",
+            "rdfs:label": "Documentation",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "icNF98.4d",
+            "sms:displayName": "documentation",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CNF98.4d",
+            "@id": "bts:ResourceType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF98.4d).",
-            "rdfs:label": "CNF98.4d",
+            "rdfs:comment": "The type of resource being stored and annotated",
+            "rdfs:label": "ResourceType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cNF98.4d",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:I28cNF",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (28NF).",
-            "rdfs:label": "I28cNF",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "i28cNF",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:28cNF",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (i28NF).",
-            "rdfs:label": "28cNF",
-            "rdfs:subClassOf": [
+                    "@id": "bts:ExperimentalData"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "28cNF",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:IcNF04.9a",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF04.9a).",
-            "rdfs:label": "IcNF04.9a",
-            "rdfs:subClassOf": [
+                    "@id": "bts:CuratedData"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "icNF04.9a",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:CNF04.9a",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF04.9a).",
-            "rdfs:label": "CNF04.9a",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Result"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "cNF04.9a",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:IcNF98.4c",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF98.4c).",
-            "rdfs:label": "IcNF98.4c",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Tool"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "icNF98.4c",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:CNF98.4c",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF98.4c).",
-            "rdfs:label": "CNF98.4c",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Report"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "cNF98.4c",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Prss56Cre;R26mT",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Prss56Cre;R26mT is a transgenic non-human animal model for Neurofibromatosis type 1, wherein the Nf1 gene is specifically inactivated in BC cells and derivatives thereof.",
-            "rdfs:label": "Prss56Cre;R26mT",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Metadata"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Prss56Cre;R26mT",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Nf1-OPG",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Nf1-OPG",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Protocol"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:Workflowreport"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Nf1-OPG",
-            "sms:required": "sms:false",
+            "sms:displayName": "resourceType",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Nf1-OPG-Arg816",
+            "@id": "bts:FileFormat",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Nf1-OPG-Arg816",
+            "rdfs:comment": "Defined format of the data file, typically corresponding to extension, but sometimes indicating more general group of files produced by the same tool or software",
+            "rdfs:label": "FileFormat",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
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-            "rdfs:comment": "A Nf2-/- mouse schwann cell line; see PMID:26554010",
-            "rdfs:label": "Nf2-/-SchwannSC(mouse)(PMID26554010)",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
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-            "sms:displayName": "Nf2-/- Schwann SC (mouse) (PMID26554010)",
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-        },
-        {
-            "@id": "bts:SC4[Mouseschwannoma]",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Mouse schwannoma knock-out cell line (RRID:CVCL_JK03)",
-            "rdfs:label": "SC4[Mouseschwannoma]",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Bashscript"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "SC4 [Mouse schwannoma]",
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-        },
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-            "@id": "bts:AC007-hTERT",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Human arachnoid cell line",
-            "rdfs:label": "AC007-hTERT",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Bedgraph"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
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-        },
-        {
-            "@id": "bts:NF2-/-AC007-hTERT",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Knock-out cell line developed by CRISPR targeting NF2 exon 8 in AC007-hTERT",
-            "rdfs:label": "NF2-/-AC007-hTERT",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Ai"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "NF2-/- AC007-hTERT",
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-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Ben-Men-1",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Human meningioma cell line (RRID:CVCL_1959)",
-            "rdfs:label": "Ben-Men-1",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Idx"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
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-            },
-            "sms:displayName": "Ben-Men-1",
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-        },
-        {
-            "@id": "bts:Humanforeskinfibroblasts",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "generic human foreskin fibroblasts, often used as a control cell in toxicology experiments",
-            "rdfs:label": "Humanforeskinfibroblasts",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Idat"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
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-            "sms:displayName": "human foreskin fibroblasts",
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-        },
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-            "@type": "rdfs:Class",
-            "rdfs:comment": "A patient-derived MPNST cell line",
-            "rdfs:label": "M3MPNST",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Bam"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "M3 MPNST",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Male",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both.",
-            "rdfs:label": "Male",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Bai"
+                },
                 {
-                    "@id": "bts:Sex"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Male",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Female",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both.",
-            "rdfs:label": "Female",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Excel"
+                },
                 {
-                    "@id": "bts:Sex"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Female",
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-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Unknown",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Not known, observed, recorded; or reported as unknown by the data contributor.",
-            "rdfs:label": "Unknown",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Powerpoint"
+                },
                 {
-                    "@id": "bts:Sex"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Unknown",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
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-        {
-            "@id": "bts:Homosapiens",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Homo sapiens with taxonomy ID: 9606 and Genbank common name: human",
-            "rdfs:label": "Homosapiens",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Tif"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Homo sapiens",
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-            "sms:validationRules": []
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-        {
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-            "@type": "rdfs:Class",
-            "rdfs:comment": "Mus musculus with taxonomy ID: 10090 and Genbank common name: house mouse",
-            "rdfs:label": "Musmusculus",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Png"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Mus musculus",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Doc"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Musmusculus(humanized)",
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-            "rdfs:comment": "Mus musculus with taxonomy ID: 10090 and Genbank common name: house mouse",
-            "rdfs:label": "Musmusculus(humanized)",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Pdf"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Mus musculus (humanized)",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Hdf"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Rattusnorvegicus",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Rattus with taxonomy ID:10116 and Genbank common name: Norway rat",
-            "rdfs:label": "Rattusnorvegicus",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Fasta"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Rattus norvegicus",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Fastq"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Drosophilamelanogaster",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Drosophila melanogaster with taxonomy ID: 7227 and Genbank common name: fruit fly",
-            "rdfs:label": "Drosophilamelanogaster",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Sam"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Drosophila melanogaster",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Vcf"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Rhesusmacaque",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Macaca mulatta with taxonomy ID: 9544 and Genbank common name: Rhesus monkey",
-            "rdfs:label": "Rhesusmacaque",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Bcf"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Rhesus macaque",
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-        },
-        {
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-            "@type": "rdfs:Class",
-            "rdfs:comment": "Pan troglodytes with taxonomy ID: 9598 and Genbank common name: chimpanzee",
-            "rdfs:label": "Pantroglodytes",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Maf"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Pan troglodytes",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Gallusgallus",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "The common domestic fowl, Chicken.",
-            "rdfs:label": "Gallusgallus",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Bed"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
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-            "sms:displayName": "Gallus gallus",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
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-        {
-            "@id": "bts:Susscrofa",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Sus scrofa with taxonomy ID: 9823 and Genbank common name: pig",
-            "rdfs:label": "Susscrofa",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Chp"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Sus scrofa",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Cel"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
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-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Oryctolaguscuniculus",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Oryctolagus cuniculus with taxonomy ID: 9986 and Genbank common name: rabbit",
-            "rdfs:label": "Oryctolaguscuniculus",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Sif"
+                },
                 {
-                    "@id": "bts:Species"
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-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Oryctolagus cuniculus",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Tsv"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
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-            ],
-            "sms:validationRules": []
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-        {
-            "@id": "bts:Daniorerio",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Danio rerio with taxonomy ID: 7955 and Genbank common name: zebrafish",
-            "rdfs:label": "Daniorerio",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Csv"
+                },
                 {
-                    "@id": "bts:Species"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Danio rerio",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Txt"
+                },
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:Plink"
+                },
+                {
+                    "@id": "bts:Bigwig"
+                },
+                {
+                    "@id": "bts:Wiggle"
+                },
+                {
+                    "@id": "bts:Gct"
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+                {
+                    "@id": "bts:Bgzip"
+                },
+                {
+                    "@id": "bts:Zip"
+                },
+                {
+                    "@id": "bts:Seg"
+                },
+                {
+                    "@id": "bts:Html"
+                },
+                {
+                    "@id": "bts:Mov"
+                },
+                {
+                    "@id": "bts:Hyperlink"
+                },
+                {
+                    "@id": "bts:Svs"
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+                {
+                    "@id": "bts:Md"
+                },
+                {
+                    "@id": "bts:Flagstat"
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+                {
+                    "@id": "bts:Gtf"
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+                {
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+                },
+                {
+                    "@id": "bts:Msf"
+                },
+                {
+                    "@id": "bts:Rmd"
+                },
+                {
+                    "@id": "bts:BednarrowPeak"
+                },
+                {
+                    "@id": "bts:BedbroadPeak"
+                },
+                {
+                    "@id": "bts:BedgappedPeak"
+                },
+                {
+                    "@id": "bts:Avi"
+                },
+                {
+                    "@id": "bts:Pzfx"
+                },
+                {
+                    "@id": "bts:Fig"
+                },
+                {
+                    "@id": "bts:Xml"
+                },
+                {
+                    "@id": "bts:Tar"
+                },
+                {
+                    "@id": "bts:Rscript"
+                },
+                {
+                    "@id": "bts:Abf"
+                },
+                {
+                    "@id": "bts:Bpm"
+                },
+                {
+                    "@id": "bts:Dat"
+                },
+                {
+                    "@id": "bts:Jpg"
+                },
+                {
+                    "@id": "bts:Locs"
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+                {
+                    "@id": "bts:Sentrixdescriptorfile"
+                },
+                {
+                    "@id": "bts:Pythonscript"
+                },
+                {
+                    "@id": "bts:Sav"
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+                {
+                    "@id": "bts:Gzip"
+                },
+                {
+                    "@id": "bts:Sdf"
+                },
+                {
+                    "@id": "bts:RData"
+                },
+                {
+                    "@id": "bts:Hic"
+                },
+                {
+                    "@id": "bts:Ab1"
+                },
+                {
+                    "@id": "bts:7z"
+                },
+                {
+                    "@id": "bts:Gff3"
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+                {
+                    "@id": "bts:Json"
+                },
+                {
+                    "@id": "bts:Sqlite"
+                },
+                {
+                    "@id": "bts:Svg"
+                },
+                {
+                    "@id": "bts:Sra"
+                },
+                {
+                    "@id": "bts:Recal"
+                },
+                {
+                    "@id": "bts:Tranches"
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+                {
+                    "@id": "bts:Mtx"
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+                {
+                    "@id": "bts:TagAlign"
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+                {
+                    "@id": "bts:Dup"
+                },
+                {
+                    "@id": "bts:DICOM"
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+                {
+                    "@id": "bts:Czi"
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+                {
+                    "@id": "bts:MzML"
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+                {
+                    "@id": "bts:SPAR"
+                },
+                {
+                    "@id": "bts:SDAT"
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+                {
+                    "@id": "bts:Nii"
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+                {
+                    "@id": "bts:PAR"
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+                {
+                    "@id": "bts:REC"
+                },
+                {
+                    "@id": "bts:Hdr"
+                },
+                {
+                    "@id": "bts:Img"
+                },
+                {
+                    "@id": "bts:Sf"
+                },
+                {
+                    "@id": "bts:MATLABscript"
+                },
+                {
+                    "@id": "bts:MATLABdata"
+                },
+                {
+                    "@id": "bts:Tom"
                 }
             ],
+            "sms:displayName": "fileFormat",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Human",
+            "@id": "bts:ProgressReportNumber",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Human",
+            "rdfs:comment": "Indicates milestone the  data is associated with. Currently only required for projects funded by NTAP, GFF, and NFRI. For GFF studies, this is the ‘progress report’ timeline. Example: if submitting data for the 6-month milestone report for NTAP, progressReportNumber=1.  Also if submitting data associated with first milestone, progressReportNumber =1",
+            "rdfs:label": "ProgressReportNumber",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TransplantationRecipientSpecies"
+                    "@id": "bts:Template"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Human",
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+                {
+                    "@id": "bts:NotApplicable"
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+            "sms:displayName": "progressReportNumber",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mouse",
+            "@id": "bts:Comments",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Mouse",
+            "rdfs:comment": "Brief free-text comments that may also be important to understanding the resource.",
+            "rdfs:label": "Comments",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TransplantationRecipientSpecies"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Mouse",
+            "sms:displayName": "comments",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:10xV2",
+            "@id": "bts:ResourceId",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "10xV2",
+            "rdfs:comment": "A UUID for a Resource from the NF Research Tools Database",
+            "rdfs:label": "ResourceId",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:DccProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "10x_v2",
+            "sms:displayName": "Resource_id",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:FACS",
+            "@id": "bts:Initiative",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "FACS",
+            "rdfs:comment": "Refers to a funding initiative. This annotation is usually handled by the DCC or funder, not the researcher. ",
+            "rdfs:label": "Initiative",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:DccProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "FACS",
+            "sms:displayName": "initiative",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:FluidigmC1",
+            "@id": "bts:FundingAgency",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "FluidigmC1",
+            "rdfs:comment": "Refers to the funding organization for the generated resource. This annotation is handled by the DCC.",
+            "rdfs:label": "FundingAgency",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:DccProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Fluidigm C1",
+            "sms:displayName": "fundingAgency",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Drop-seq",
+            "@id": "bts:CreatedOn",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Drop-seq",
+            "rdfs:comment": "Refers to when the resource was created on the platform.",
+            "rdfs:label": "CreatedOn",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "drop-seq",
+            "sms:displayName": "createdOn",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:InDrop",
+            "@id": "bts:CreatedBy",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "InDrop",
+            "rdfs:comment": "Refers to the user who created the resource on the platform.",
+            "rdfs:label": "CreatedBy",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "inDrop",
+            "sms:displayName": "createdBy",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mouthpipette",
+            "@id": "bts:ModifiedBy",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Mouthpipette",
+            "rdfs:comment": "Refers to a user who last modified the resource on the platform.",
+            "rdfs:label": "ModifiedBy",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mouth pipette",
+            "sms:displayName": "modifiedBy",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Enzymatic",
+            "@id": "bts:Id",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Enzymatic",
+            "rdfs:comment": "The entity id for the resource automatically assigned by the platform.",
+            "rdfs:label": "Id",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "enzymatic",
+            "sms:displayName": "id",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mechanical",
+            "@id": "bts:Etag",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Mechanical",
+            "rdfs:comment": "Synapse employs an Optimistic Concurrency Control (OCC) scheme to handle concurrent updates. The E-Tag changes every time an entity is updated it is used to detect when a client's current representation of an entity is out-of-date.",
+            "rdfs:label": "Etag",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DissociationMethod"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mechanical",
+            "sms:displayName": "etag",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Viablyfrozen",
+            "@id": "bts:ParentId",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Viablyfrozen",
+            "rdfs:comment": "The id of the parent resource, i.e. the parent folder on the platform. ",
+            "rdfs:label": "ParentId",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Viably frozen",
+            "sms:displayName": "parentId",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Nervetissue",
+            "@id": "bts:BenefactorId",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature.",
-            "rdfs:label": "Nervetissue",
+            "rdfs:comment": "The id of the resource from which access control is inherited.",
+            "rdfs:label": "BenefactorId",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "nerve tissue",
+            "sms:displayName": "benefactorId",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Opticnerve",
+            "@id": "bts:CurrentVersion",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The nerve that carries messages from the retina to the brain.",
-            "rdfs:label": "Opticnerve",
+            "rdfs:comment": "(Versionable entities only) The current version number of the resource.",
+            "rdfs:label": "CurrentVersion",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "optic nerve",
+            "sms:displayName": "currentVersion",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Serum",
+            "@id": "bts:DataFileHandleId",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Liquid derived from blood plasma that has clotting factors removed.",
-            "rdfs:label": "Serum",
+            "rdfs:comment": "(Files only) Refers to the id of the file.",
+            "rdfs:label": "DataFileHandleId",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "serum",
+            "sms:displayName": "dataFileHandleId",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Plasma",
+            "@id": "bts:ContentSize",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Plasma is the fluid (noncellular) portion of the circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation.",
-            "rdfs:label": "Plasma",
+            "rdfs:comment": "(Files only) File size calculated by the platform.",
+            "rdfs:label": "ContentSize",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "plasma",
+            "sms:displayName": "contentSize",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Splenocyte",
+            "@id": "bts:Type",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any leukocyte that is part of a spleen.",
-            "rdfs:label": "Splenocyte",
+            "rdfs:comment": "Refers to the type of the resource on the platform, e.g. “file”.",
+            "rdfs:label": "Type",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "splenocyte",
+            "sms:displayName": "type",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Blood",
+            "@id": "bts:ConcreteType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A fluid that is composed of blood plasma and erythrocytes.",
-            "rdfs:label": "Blood",
+            "rdfs:comment": "Refers to the class model the data platform uses for representing the resource. This is a low-level field set by the platform and is not a user annotation.",
+            "rdfs:label": "ConcreteType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SynapseProperty"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "blood",
+            "sms:displayName": "concreteType",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Primarytumor",
+            "@id": "bts:Author",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A primary tumor is the tumor at the initial site of cancer, not where the cancer may have spread or metastasized, called the secondary tumor.",
-            "rdfs:label": "Primarytumor",
+            "rdfs:comment": "The author of the resource; preferably use an ORCID ID, GitHub profile link, etc., if available and a text name if not.",
+            "rdfs:label": "Author",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "primary tumor",
+            "sms:displayName": "author",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:TumorType"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Embryonictissue",
+            "@id": "bts:License",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A portion of tissue that is part of an embryo.",
-            "rdfs:label": "Embryonictissue",
+            "rdfs:comment": "Link to a license or name of license applicable for the resource.",
+            "rdfs:label": "License",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "embryonic tissue",
+            "sms:displayName": "license",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Meninges",
+            "@id": "bts:Allograft",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The three thin layers of tissue that cover and protect the brain and spinal cord.",
-            "rdfs:label": "Meninges",
+            "rdfs:comment": "Tissues, cells, or organs transplanted between genetically different individuals of the same species",
+            "rdfs:label": "Allograft",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TransplantationType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "meninges",
+            "sms:displayName": "allograft",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bonemarrow",
+            "@id": "bts:Xenograft",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells.",
-            "rdfs:label": "Bonemarrow",
+            "rdfs:comment": "Tissues, cells or organs transplanted between animals of different species",
+            "rdfs:label": "Xenograft",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TransplantationType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bone marrow",
+            "sms:displayName": "xenograft",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:TransplantationRecipientSpecies"
+                },
+                {
+                    "@id": "bts:TransplantationRecipientTissue"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BuccalMucosa",
+            "@id": "bts:Autograft",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The mucosal membranes located on the inside of the cheek, in the buccal cavity.The inner lining of the cheeks.",
-            "rdfs:label": "BuccalMucosa",
+            "rdfs:comment": "Transplant comprised of an individual's own tissue, transferred from one part of the body to another.",
+            "rdfs:label": "Autograft",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TransplantationType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Buccal Mucosa",
+            "sms:displayName": "autograft",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:TransplantationRecipientSpecies"
+                },
+                {
+                    "@id": "bts:TransplantationRecipientTissue"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DorsalRootGanglion",
+            "@id": "bts:Isograft",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Ganglion with sensory function within the vertebral column.",
-            "rdfs:label": "DorsalRootGanglion",
+            "rdfs:comment": "Tissues, cells or organs transplanted between genetically identical individuals",
+            "rdfs:label": "Isograft",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TransplantationType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Dorsal Root Ganglion",
+            "sms:displayName": "isograft",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Cerebralcortex",
+            "@id": "bts:Seconds",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The outer layer of the cerebrum composed of neurons and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other higher levels of mental function.",
-            "rdfs:label": "Cerebralcortex",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Seconds",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TimePointUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cerebral cortex",
+            "sms:displayName": "seconds",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sciaticnerve",
+            "@id": "bts:Minutes",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The longest single nerve that is formed by the merging of the ventral rami of the L4, L5, and S1 in the pelvis and passes down the lower limb where it divides into the common peroneal and tibial nerves",
-            "rdfs:label": "Sciaticnerve",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Minutes",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TimePointUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sciatic nerve",
+            "sms:displayName": "minutes",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Unspecified",
+            "@id": "bts:Hours",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Unspecified tissue or tissues from an organ.",
-            "rdfs:label": "Unspecified",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Hours",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TimePointUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "unspecified",
+            "sms:displayName": "hours",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Wholebrain",
+            "@id": "bts:Days",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Brain tissue not limited to a specific region.",
-            "rdfs:label": "Wholebrain",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Days",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TimePointUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "whole brain",
+            "sms:displayName": "days",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BuffyCoat",
+            "@id": "bts:Weeks",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The middle layer of an anticoagulated blood specimen following separation by centrifugation. It contains most of the white blood cells and platelets.",
-            "rdfs:label": "BuffyCoat",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Weeks",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:TimePointUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Buffy Coat",
+            "sms:displayName": "weeks",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Normal",
+            "@id": "bts:Months",
             "@type": "rdfs:Class",
-            "rdfs:comment": "No pathological entity observable.",
-            "rdfs:label": "Normal",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Months",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:TimePointUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "normal",
+            "sms:displayName": "months",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Connectivetissue",
+            "@id": "bts:Quarters",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Connectivetissue",
+            "rdfs:comment": "Time point unit referring to quarters in a year.",
+            "rdfs:label": "Quarters",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "connective tissue",
+            "sms:displayName": "quarters",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tumor-adjacentnormal",
+            "@id": "bts:TransplantationType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tissue comprised of morphologically normal tissue collected from the area immediately surrounding a tumor.",
-            "rdfs:label": "Tumor-adjacentnormal",
+            "rdfs:comment": "Type of transplantation involved in the experiment, derived from MESH",
+            "rdfs:label": "TransplantationType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:Cancer"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tumor-adjacent normal",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Allograft"
+                },
+                {
+                    "@id": "bts:Xenograft"
+                },
+                {
+                    "@id": "bts:Autograft"
+                },
+                {
+                    "@id": "bts:Isograft"
+                }
+            ],
+            "sms:displayName": "transplantationType",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:TransplantationRecipientSpecies"
+                },
+                {
+                    "@id": "bts:TransplantationRecipientTissue"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PDXtissue",
+            "@id": "bts:TransplantationRecipientSpecies",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Patient derived xenograft tissue",
-            "rdfs:label": "PDXtissue",
+            "rdfs:comment": "Species into which donor tissue was grown",
+            "rdfs:label": "TransplantationRecipientSpecies",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:Cancer"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "PDX tissue",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Human"
+                },
+                {
+                    "@id": "bts:Mouse"
+                }
+            ],
+            "sms:displayName": "transplantationRecipientSpecies",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CDXtissue",
+            "@id": "bts:TimePointUnit",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Cell line derived xenograft tissue",
-            "rdfs:label": "CDXtissue",
+            "rdfs:comment": "For timed experiments this represents the unit of time measured",
+            "rdfs:label": "TimePointUnit",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:Cancer"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "CDX tissue",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Seconds"
+                },
+                {
+                    "@id": "bts:Minutes"
+                },
+                {
+                    "@id": "bts:Hours"
+                },
+                {
+                    "@id": "bts:Days"
+                },
+                {
+                    "@id": "bts:Weeks"
+                },
+                {
+                    "@id": "bts:Months"
+                },
+                {
+                    "@id": "bts:Quarters"
+                }
+            ],
+            "sms:displayName": "timePointUnit",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Organoid",
+            "@id": "bts:ExperimentalCondition",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Organoids are three-dimensional cell culture models that self-organize into complex organ-like tissues.",
-            "rdfs:label": "Organoid",
+            "rdfs:comment": "A free-text description of the experimental condition (e.g. 5 mM doxorubicin).",
+            "rdfs:label": "ExperimentalCondition",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "organoid",
+            "sms:displayName": "experimentalCondition",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Spheroid",
+            "@id": "bts:ExperimentalTimepoint",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Spheroids are 3D culture systems that can be used to model multicellular tumors; more broadly, spheroids can be defined as cell aggregates cultured on nonadherent substrates.",
-            "rdfs:label": "Spheroid",
+            "rdfs:comment": "The numeric value indicating the time elapsed from the beginning of the experiment at which the specimen was collected. Use in tandem with timePointUnit",
+            "rdfs:label": "ExperimentalTimepoint",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "spheroid",
+            "sms:displayName": "experimentalTimepoint",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:TimePointUnit"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Microtissue",
+            "@id": "bts:TransplantationRecipientTissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Microtissue usually refers to the microtissue formed by the aggregation of seed cells under the action of cell-cell or cell-extracellular matrix (ECM). Compared with traditional cell monolayer culture, cells are cultivated into a three-dimensional microstructure in a specific way. The microstructure characteristics of microtissue are similar to natural tissues and can promote cell proliferation and differentiation.",
-            "rdfs:label": "Microtissue",
+            "rdfs:comment": "Tissue into which a xenograph sample is transplanted",
+            "rdfs:label": "TransplantationRecipientTissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "microtissue",
+            "sms:displayName": "transplantationRecipientTissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Retina",
+            "@id": "bts:ExperimentId",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A light-sensitive membrane that lines the back wall of the eyeball. The retina is continuous with the optic nerve and this way transmits optical images to the brain. [ NCI ]",
-            "rdfs:label": "Retina",
+            "rdfs:comment": "When applicable, an optional identifier that can be used to distinguish or group the experiments that generated the data; also can be used to denote internal batch reference if needed.",
+            "rdfs:label": "ExperimentId",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "retina",
+            "sms:displayName": "experimentId",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Teratoma",
+            "@id": "bts:CompoundName",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TT",
-            "rdfs:label": "Teratoma",
+            "rdfs:comment": "Common name for a compound, e.g. “Selumetinib” (https://pubchem.ncbi.nlm.nih.gov/compound/10127622)",
+            "rdfs:label": "CompoundName",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Teratoma",
+            "sms:displayName": "compoundName",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:InChIKey"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CutaneousNeurofibroma",
+            "@id": "bts:CompoundDose",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neurofibroma that grows along small branches of nerves in the dermis in patients with neurofibromatosis. It presents as a solid cutaneous tumor.",
-            "rdfs:label": "CutaneousNeurofibroma",
+            "rdfs:comment": "A dose quantity for the treatment compound. To be used with compoundDoseUnit.",
+            "rdfs:label": "CompoundDose",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Cutaneous Neurofibroma",
+            "sms:displayName": "compoundDose",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:CompoundDoseUnit"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SubcutaneousNeurofibroma",
+            "@id": "bts:CompoundDoseUnit",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neurofibroma that occurs along the peripheral nerves beneath the skin.",
-            "rdfs:label": "SubcutaneousNeurofibroma",
+            "rdfs:comment": "A unit associated with the value(s) in compoundDose.",
+            "rdfs:label": "CompoundDoseUnit",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Subcutaneous Neurofibroma",
+            "sms:displayName": "compoundDoseUnit",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PlexiformNeurofibroma",
+            "@id": "bts:InChIKey",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An elongated and multinodular neurofibroma, formed when the tumor involves either multiple trunks of a plexus or multiple fascicles of a large nerve, such as the sciatic. Some plexiform neurofibromas resemble a bag of worms, others produce a massive ropy enlargement of the nerve.",
-            "rdfs:label": "PlexiformNeurofibroma",
+            "rdfs:comment": "A unique hash key for a compound, e.g. for “Selumetinib”, the key is CYOHGALHFOKKQC-UHFFFAOYSA-N (https://pubchem.ncbi.nlm.nih.gov/compound/10127622#section=InChI-Key). This is a more reliable identifier than the compound name and should be used if available.",
+            "rdfs:label": "InChIKey",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Plexiform Neurofibroma",
+            "sms:displayName": "InChIKey",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AtypicalNeurofibroma",
+            "@id": "bts:GenePerturbationType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neurofibroma characterized by the presence of cellular pleomorphism.",
-            "rdfs:label": "AtypicalNeurofibroma",
+            "rdfs:comment": "Specific way in which a single gene was perturbed in a sample",
+            "rdfs:label": "GenePerturbationType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Cancer"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Atypical Neurofibroma",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Overexpression"
+                },
+                {
+                    "@id": "bts:Knockdown"
+                },
+                {
+                    "@id": "bts:Knockout"
+                },
+                {
+                    "@id": "bts:Non-targetingcontrol"
+                },
+                {
+                    "@id": "bts:NotApplicable"
+                }
+            ],
+            "sms:displayName": "genePerturbationType",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MalignantPeripheralNerveSheathTumor",
+            "@id": "bts:GenePerturbationTechnology",
             "@type": "rdfs:Class",
-            "rdfs:comment": "MPNST",
-            "rdfs:label": "MalignantPeripheralNerveSheathTumor",
+            "rdfs:comment": "Technology used to perform gene perturbation",
+            "rdfs:label": "GenePerturbationTechnology",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Cancer"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Malignant Peripheral Nerve Sheath Tumor",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:RNAi"
+                },
+                {
+                    "@id": "bts:CRISPR"
+                },
+                {
+                    "@id": "bts:CRERecombinase"
+                }
+            ],
+            "sms:displayName": "genePerturbationTechnology",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Glioma",
+            "@id": "bts:GenePerturbed",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas.",
-            "rdfs:label": "Glioma",
+            "rdfs:comment": "The HUGO gene symbol for the gene that is perturbed.",
+            "rdfs:label": "GenePerturbed",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:SageCommunity"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Glioma",
+            "sms:displayName": "genePerturbed",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:GenePerturbationType"
+                },
+                {
+                    "@id": "bts:GenePerturbationTechnology"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Low-GradeGliomaNOS",
+            "@id": "bts:JAX",
             "@type": "rdfs:Class",
-            "rdfs:comment": "LGGNOS",
-            "rdfs:label": "Low-GradeGliomaNOS",
+            "rdfs:comment": "The Jackson Laboratory",
+            "rdfs:label": "JAX",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:IndividualIdSource"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Low-Grade Glioma NOS",
+            "sms:displayName": "JAX",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PilocyticAstrocytoma",
+            "@id": "bts:SageCommunity",
             "@type": "rdfs:Class",
-            "rdfs:comment": "PAST",
-            "rdfs:label": "PilocyticAstrocytoma",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SageCommunity",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Pilocytic Astrocytoma",
+            "sms:displayName": "sageCommunity",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AtypicalPilocyticAstrocytoma",
+            "@id": "bts:Workflow",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Pilocytic astrocytoma with atypical features.",
-            "rdfs:label": "AtypicalPilocyticAstrocytoma",
+            "rdfs:comment": "Name and version of the workflow used to generate/analyze the data",
+            "rdfs:label": "Workflow",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Atypical Pilocytic Astrocytoma",
+            "sms:displayName": "workflow",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:WorkflowLink"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PilomyxoidAstrocytoma",
+            "@id": "bts:WorkflowLink",
             "@type": "rdfs:Class",
-            "rdfs:comment": "PMA",
-            "rdfs:label": "PilomyxoidAstrocytoma",
+            "rdfs:comment": "Workflow URL reference",
+            "rdfs:label": "WorkflowLink",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Pilomyxoid Astrocytoma",
+            "sms:displayName": "workflowLink",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DiffuseAstrocytoma",
+            "@id": "bts:GenomicReference",
             "@type": "rdfs:Class",
-            "rdfs:comment": "DA",
-            "rdfs:label": "DiffuseAstrocytoma",
+            "rdfs:comment": "Version of genome reference used for alignment in processing workflow",
+            "rdfs:label": "GenomicReference",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Diffuse Astrocytoma",
+            "sms:displayName": "genomicReference",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GlioblastomaMultiforme",
+            "@id": "bts:AverageInsertSize",
             "@type": "rdfs:Class",
-            "rdfs:comment": "GBM",
-            "rdfs:label": "GlioblastomaMultiforme",
+            "rdfs:comment": "Average insert size as reported by samtools",
+            "rdfs:label": "AverageInsertSize",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Glioblastoma Multiforme",
+            "sms:displayName": "averageInsertSize",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AnaplasticPilocyticAstrocytoma",
+            "@id": "bts:AverageReadLength",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Pilocytic astrocytoma with anaplastic features exhibits a spectrum of morphologies and is associated with decreased survival when compared with typical PA.",
-            "rdfs:label": "AnaplasticPilocyticAstrocytoma",
+            "rdfs:comment": "Average read length collected from samtools",
+            "rdfs:label": "AverageReadLength",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Anaplastic Pilocytic Astrocytoma",
+            "sms:displayName": "averageReadLength",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PleomorphicXanthoastrocytoma",
+            "@id": "bts:AverageBaseQuality",
             "@type": "rdfs:Class",
-            "rdfs:comment": "PXA",
-            "rdfs:label": "PleomorphicXanthoastrocytoma",
+            "rdfs:comment": "Average base quality collected from samtools",
+            "rdfs:label": "AverageBaseQuality",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Pleomorphic Xanthoastrocytoma",
+            "sms:displayName": "averageBaseQuality",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Oligoastrocytoma",
+            "@id": "bts:PairsOnDifferentChr",
             "@type": "rdfs:Class",
-            "rdfs:comment": "OAST",
-            "rdfs:label": "Oligoastrocytoma",
+            "rdfs:comment": "Pairs on different chromosomes collected from samtools",
+            "rdfs:label": "PairsOnDifferentChr",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Oligoastrocytoma",
+            "sms:displayName": "pairsOnDifferentChr",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:High-GradeGliomaNOS",
+            "@id": "bts:ReadsDuplicatedPercent",
             "@type": "rdfs:Class",
-            "rdfs:comment": "HGGNOS",
-            "rdfs:label": "High-GradeGliomaNOS",
+            "rdfs:comment": "Percent of duplicated reads collected from samtools",
+            "rdfs:label": "ReadsDuplicatedPercent",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "High-Grade Glioma NOS",
+            "sms:displayName": "readsDuplicatedPercent",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Unknown",
+            "@id": "bts:ReadsMappedPercent",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A tumor of unknown origin, or tumor type missing. ",
-            "rdfs:label": "Unknown",
+            "rdfs:comment": "Percent of mapped reads collected from samtools",
+            "rdfs:label": "ReadsMappedPercent",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Unknown",
+            "sms:displayName": "readsMappedPercent",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AnaplasticAstrocytoma",
+            "@id": "bts:MeanCoverage",
             "@type": "rdfs:Class",
-            "rdfs:comment": "AASTR",
-            "rdfs:label": "AnaplasticAstrocytoma",
+            "rdfs:comment": "Mean coverage for whole genome sequencing, or mean target coverage for whole exome and targeted sequencing, collected from Picard Tools",
+            "rdfs:label": "MeanCoverage",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Anaplastic Astrocytoma",
+            "sms:displayName": "meanCoverage",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Glioblastoma",
+            "@id": "bts:ProportionCoverage10x",
             "@type": "rdfs:Class",
-            "rdfs:comment": "GB",
-            "rdfs:label": "Glioblastoma",
+            "rdfs:comment": "Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 10X or greater coverage from Picard Tools",
+            "rdfs:label": "ProportionCoverage10x",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Glioblastoma",
+            "sms:displayName": "proportionCoverage10x",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Schwannoma",
+            "@id": "bts:ProportionCoverage30x",
             "@type": "rdfs:Class",
-            "rdfs:comment": "SCHW",
-            "rdfs:label": "Schwannoma",
+            "rdfs:comment": "Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 30X or greater coverage from Picard Tools",
+            "rdfs:label": "ProportionCoverage30x",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Schwannoma",
+            "sms:displayName": "proportionCoverage30x",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Meningioma",
+            "@id": "bts:Head",
             "@type": "rdfs:Class",
-            "rdfs:comment": "MNG",
-            "rdfs:label": "Meningioma",
+            "rdfs:comment": "The head is the anterior-most division of the body.",
+            "rdfs:label": "Head",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Meningioma",
+            "sms:displayName": "head",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MassiveSoftTissueNeurofibroma",
+            "@id": "bts:Lymphnode",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Massive soft tissue neurofibroma is characterized  by local infiltration and extension to multiple nerve branches,  as well as substantial overgrowth of adjacent soft tissue and  skin, which distinguishes it from its more benign variant, plexiform neurofibroma. With striking presentation and  severe dysmorphism, massive soft tissue neurofibroma is also labeled elephantiasis neuromatosa. Although considered benign it  shares similarities with malignant peripheral nerve sheath  tumors such as local infiltration and cell mitogenesis. Massive soft tissue neurofibroma is associated with significant morbidity and mortality and almost no response to  conventional chemotherapy and radiotherapy. Surgery is eventually pursued, although bleeding may be a life-threatening  complication as massive soft tissue neurofibromas are highly  vascularized.",
-            "rdfs:label": "MassiveSoftTissueNeurofibroma",
+            "rdfs:comment": "A bean-shaped organ surrounded by a connective tissue capsule.",
+            "rdfs:label": "Lymphnode",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Massive Soft Tissue Neurofibroma",
+            "sms:displayName": "lymph node",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DiffuseInfiltratingNeurofibroma",
+            "@id": "bts:Kidney",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Diffuse infiltrating neurofibroma can present as slow-growing, soft tissue masses with overlying skin thickening. These le-sions infiltrate the dermis and the subcutaneous tissue and  characteristically spread along the connective tissues enveloping islands of normal fat. Some of these lesions develop fatty proliferation and can mimic lipomas,  angiolipomas, or angiomyolipomas on imaging and histological evaluation ",
-            "rdfs:label": "DiffuseInfiltratingNeurofibroma",
+            "rdfs:comment": "One of the two bean-shaped organs located on each side of the spine in the retroperitoneum.",
+            "rdfs:label": "Kidney",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Diffuse Infiltrating Neurofibroma",
+            "sms:displayName": "kidney",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:LocalizedNeurofibroma",
+            "@id": "bts:Skin",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "LocalizedNeurofibroma",
+            "rdfs:comment": "The integument of an animal (as a fur-bearing mammal or a bird) separated from the body usually with its hair or feathers.",
+            "rdfs:label": "Skin",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Localized Neurofibroma",
+            "sms:displayName": "skin",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NeurofibromawithDegenerativeAtypia",
+            "@id": "bts:Mammarygland",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NeurofibromawithDegenerativeAtypia",
+            "rdfs:comment": "A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males.",
+            "rdfs:label": "Mammarygland",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Neurofibroma with Degenerative Atypia",
+            "sms:displayName": "mammary gland",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Neurofibroma",
+            "@id": "bts:Nerves",
             "@type": "rdfs:Class",
-            "rdfs:comment": "NFIB",
-            "rdfs:label": "Neurofibroma",
+            "rdfs:comment": "Any of the filamentous bands of nervous tissue that connect parts of the nervous system with the other organs, conduct nervous impulses, and are made up of axons and dendrites together with protective and supportive structures.",
+            "rdfs:label": "Nerves",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Neurofibroma",
+            "sms:displayName": "nerves",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AnaplasticPleomorphicXanthoastrocytoma",
+            "@id": "bts:Brain",
             "@type": "rdfs:Class",
-            "rdfs:comment": "APXA",
-            "rdfs:label": "AnaplasticPleomorphicXanthoastrocytoma",
+            "rdfs:comment": "The portion of the vertebrate central nervous system that constitutes the organ of thought and neural coordination.",
+            "rdfs:label": "Brain",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Anaplastic Pleomorphic Xanthoastrocytoma",
+            "sms:displayName": "brain",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Ganglioglioma",
+            "@id": "bts:Blood",
             "@type": "rdfs:Class",
-            "rdfs:comment": "GNG",
-            "rdfs:label": "Ganglioglioma",
+            "rdfs:comment": "The fluid that circulates in the heart, arteries, capillaries, and veins of a vertebrate animal carrying nourishment and oxygen to and bringing away waste products from all parts of the body.",
+            "rdfs:label": "Blood",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Ganglioglioma",
+            "sms:displayName": "blood",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AnaplasticGanglioglioma",
+            "@id": "bts:Breast",
             "@type": "rdfs:Class",
-            "rdfs:comment": "AGNG",
-            "rdfs:label": "AnaplasticGanglioglioma",
+            "rdfs:comment": "The fore or ventral part of the body between the neck and the abdomen.",
+            "rdfs:label": "Breast",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Anaplastic Ganglioglioma",
+            "sms:displayName": "breast",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:OpticPathwayGlioma",
+            "@id": "bts:Colon",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A glioma that affects the optic nerve. This condition can be seen in association with neurofibromatosis 1. It is most commonly seen in the pediatric age group.",
-            "rdfs:label": "OpticPathwayGlioma",
+            "rdfs:comment": "The part of the large intestine that extends from the cecum to the rectum.",
+            "rdfs:label": "Colon",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Optic Pathway Glioma",
+            "sms:displayName": "colon",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NotApplicable",
+            "@id": "bts:Lung",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "NotApplicable",
+            "rdfs:comment": "One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates.",
+            "rdfs:label": "Lung",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Not Applicable",
+            "sms:displayName": "lung",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ColorectalAdenocarcinoma",
+            "@id": "bts:Prostate",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(COADREAD) The most common type of colorectal carcinoma. It is chararactized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa.",
-            "rdfs:label": "ColorectalAdenocarcinoma",
+            "rdfs:comment": "Lobular organ the parenchyma of which has as its parts glandular acini which are continuous with the prostatic part of the urethra.",
+            "rdfs:label": "Prostate",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Colorectal Adenocarcinoma",
+            "sms:displayName": "prostate",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ColorectalCarcinoma",
+            "@id": "bts:Pancreas",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A malignant epithelial neoplasm that arrises from the colon or rectum and invates through the muscularis mucosa into the submucosa. 95 percent of colorectal carcinoma are colorectal adenocarcinoma -- use this more specific term if it applies.",
-            "rdfs:label": "ColorectalCarcinoma",
+            "rdfs:comment": "A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon.",
+            "rdfs:label": "Pancreas",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Colorectal Carcinoma",
+            "sms:displayName": "pancreas",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:RecurrentMPNST",
+            "@id": "bts:Ovary",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The reemergence of malignant peripheral nerve sheath tumor after a period of remission.",
-            "rdfs:label": "RecurrentMPNST",
+            "rdfs:comment": "One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones.",
+            "rdfs:label": "Ovary",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Recurrent MPNST",
+            "sms:displayName": "ovary",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:JuvenileMyelomonocyticLeukemia",
+            "@id": "bts:Spleen",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(JMML) A myelodysplastic/myeloproliferative neoplasm of childhood that is characterized by proliferation principally of the granulocytic and monocytic lineages",
-            "rdfs:label": "JuvenileMyelomonocyticLeukemia",
+            "rdfs:comment": "A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes.",
+            "rdfs:label": "Spleen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Juvenile Myelomonocytic Leukemia",
+            "sms:displayName": "spleen",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sarcoma",
+            "@id": "bts:Bonemarrow",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(SARCNOS) An usually aggressive malignant neoplasm of the soft tissue or bone...Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.",
-            "rdfs:label": "Sarcoma",
+            "rdfs:comment": "The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells.",
+            "rdfs:label": "Bonemarrow",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Sarcoma",
+            "sms:displayName": "bone marrow",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fibromatosis",
+            "@id": "bts:BursaOfFabricius",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern.",
-            "rdfs:label": "Fibromatosis",
+            "rdfs:comment": "An epithelial outgrowth of lymphoid tissue in the cloaca of young birds, responsible for B-lymphocyte maturation. It undergoes atrophy and involution at six months of age.",
+            "rdfs:label": "BursaOfFabricius",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Fibromatosis",
+            "sms:displayName": "Bursa Of Fabricius",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fibrosarcoma",
+            "@id": "bts:Nose",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(FIBS) A malignant mesenchymal fibroblastic neoplasm affecting the soft tissue and bone.",
-            "rdfs:label": "Fibrosarcoma",
+            "rdfs:comment": "A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract.",
+            "rdfs:label": "Nose",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Fibrosarcoma",
+            "sms:displayName": "nose",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NecroticNeoplasm",
+            "@id": "bts:Eye",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neoplasm characterized by focal or diffuse tumor cell necrosis.",
-            "rdfs:label": "NecroticNeoplasm",
+            "rdfs:comment": "The organ of sight or vision. [ NCI ]",
+            "rdfs:label": "Eye",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Necrotic Neoplasm",
+            "sms:displayName": "Eye",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HemorrhagicNeoplasm",
+            "@id": "bts:Mesentery",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A neoplasm with hemorrhagic findings.",
-            "rdfs:label": "HemorrhagicNeoplasm",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Mesentery",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Hemorrhagic Neoplasm",
+            "sms:displayName": "mesentery",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NF1-AssociatedTumor",
+            "@id": "bts:Scalp",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Unspecified NF1-associated tumor; use a more specific tumor classification if available.",
-            "rdfs:label": "NF1-AssociatedTumor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Scalp",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NF1-Associated Tumor",
+            "sms:displayName": "scalp",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:NF2-AssociatedTumor",
+            "@id": "bts:Pelvis",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Unspecified NF2-associated tumor; use a more specific tumor classification if available.",
-            "rdfs:label": "NF2-AssociatedTumor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Pelvis",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "NF2-Associated Tumor",
+            "sms:displayName": "pelvis",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ANNUBP",
+            "@id": "bts:Neck",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Atypical neurofibromatous neoplasms of uncertain biologic potential is a provisional classification for lesions displaying at least two features: atypia, loss of neurofibroma architecture, high cellularity, and/or mitotic activity >1/50 but <3/10 high power fields. They can be inconsistently diagnosed as atypical neurofibroma or low-grade MPNST. See https://pubmed.ncbi.nlm.nih.gov/28551330/.",
-            "rdfs:label": "ANNUBP",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Neck",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "ANNUBP",
+            "sms:displayName": "neck",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tumor",
+            "@id": "bts:Leg",
             "@type": "rdfs:Class",
-            "rdfs:comment": "General term for tumor sample – use when it is unknown when a more specific clinical classification is unknown, e.g. whether it is primary or secondary.",
-            "rdfs:label": "Tumor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Leg",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tumor",
+            "sms:displayName": "leg",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Metastatictumor",
+            "@id": "bts:Liver",
             "@type": "rdfs:Class",
-            "rdfs:comment": "For neoplasms, a non-infiltrating and non-metastasizing neoplastic process that is characterized by the absence of morphologic features associated with malignancy (e.g., severe atypia, nuclear pleomorphism, tumor cell necrosis, and abnormal mitoses).",
-            "rdfs:label": "Metastatictumor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Liver",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:Organ"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "metastatic tumor",
+            "sms:displayName": "liver",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Metastatic/recurrenttumor",
+            "@id": "bts:Axilla",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A tumor with metastatic/recurrent characteristic.",
-            "rdfs:label": "Metastatic/recurrenttumor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Axilla",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "metastatic/recurrent tumor",
+            "sms:displayName": "axilla",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Recurrenttumor",
+            "@id": "bts:Acetabulum",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A tumor described with recurrent characteristic.",
-            "rdfs:label": "Recurrenttumor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Acetabulum",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Tissue"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "recurrent tumor",
+            "sms:displayName": "acetabulum",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:TumorType",
+            "@id": "bts:Forearm",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The type of tumor that the biospecimen used to generate the data were collected from.",
-            "rdfs:label": "TumorType",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Forearm",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Cancer"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Teratoma"
-                },
-                {
-                    "@id": "bts:CutaneousNeurofibroma"
-                },
-                {
-                    "@id": "bts:SubcutaneousNeurofibroma"
-                },
-                {
-                    "@id": "bts:PlexiformNeurofibroma"
-                },
-                {
-                    "@id": "bts:AtypicalNeurofibroma"
-                },
-                {
-                    "@id": "bts:MalignantPeripheralNerveSheathTumor"
-                },
-                {
-                    "@id": "bts:Glioma"
-                },
-                {
-                    "@id": "bts:Low-GradeGliomaNOS"
-                },
-                {
-                    "@id": "bts:PilocyticAstrocytoma"
-                },
-                {
-                    "@id": "bts:AtypicalPilocyticAstrocytoma"
-                },
-                {
-                    "@id": "bts:PilomyxoidAstrocytoma"
-                },
-                {
-                    "@id": "bts:DiffuseAstrocytoma"
-                },
-                {
-                    "@id": "bts:GlioblastomaMultiforme"
-                },
-                {
-                    "@id": "bts:AnaplasticPilocyticAstrocytoma"
-                },
-                {
-                    "@id": "bts:PleomorphicXanthoastrocytoma"
-                },
-                {
-                    "@id": "bts:Oligoastrocytoma"
-                },
-                {
-                    "@id": "bts:High-GradeGliomaNOS"
-                },
-                {
-                    "@id": "bts:Unknown"
-                },
-                {
-                    "@id": "bts:AnaplasticAstrocytoma"
-                },
-                {
-                    "@id": "bts:Glioblastoma"
-                },
-                {
-                    "@id": "bts:Schwannoma"
-                },
-                {
-                    "@id": "bts:Meningioma"
-                },
-                {
-                    "@id": "bts:MassiveSoftNeurofibroma"
-                },
-                {
-                    "@id": "bts:DiffuseInfiltratingNeurofibroma"
-                },
-                {
-                    "@id": "bts:LocalizedNeurofibroma"
-                },
-                {
-                    "@id": "bts:NeurofibromawithDegenerativeAtypia"
-                },
-                {
-                    "@id": "bts:Neurofibroma"
-                },
-                {
-                    "@id": "bts:AnaplasticPleomorphicXanthoastrocytoma"
-                },
-                {
-                    "@id": "bts:Ganglioglioma"
-                },
-                {
-                    "@id": "bts:AnaplasticGanglioglioma"
-                },
-                {
-                    "@id": "bts:OpticPathwayGlioma"
-                },
-                {
-                    "@id": "bts:NotApplicable"
-                },
-                {
-                    "@id": "bts:ColorectalCarcinoma"
-                },
-                {
-                    "@id": "bts:RecurrentMPNST"
-                },
-                {
-                    "@id": "bts:JuvenileMyelomonocyticLeukemia"
-                },
-                {
-                    "@id": "bts:Sarcoma"
-                },
-                {
-                    "@id": "bts:Fibromatosis"
-                },
-                {
-                    "@id": "bts:Fibrosarcoma"
-                },
-                {
-                    "@id": "bts:NecroticNeoplasm"
-                },
-                {
-                    "@id": "bts:HemorrhagicNeoplasm"
-                },
-                {
-                    "@id": "bts:NF1-AssociatedTumor"
-                },
+            "sms:displayName": "forearm",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Muscle",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Muscle",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NF2-AssociatedTumor"
+                    "@id": "bts:BodyPart"
                 }
             ],
-            "sms:displayName": "tumorType",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "muscle",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Diagnosis",
+            "@id": "bts:Finger",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A diagnosis is the result of a medical investigation to identify a disorder from its signs and symptoms.",
-            "rdfs:label": "Diagnosis",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Finger",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Neurofibromatosistype1"
-                },
-                {
-                    "@id": "bts:Neurofibromatosistype2"
-                },
+            "sms:displayName": "finger",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Thoracicspine",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Thoracicspine",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Schwannomatosis"
-                },
+                    "@id": "bts:BodyPart"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "thoracic spine",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Groin",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Anatomically also known as the inguinal part of abdomen.",
+            "rdfs:label": "Groin",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Unknown"
-                },
+                    "@id": "bts:BodyPart"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "groin",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Back",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Anatomically also known as the dorsum.",
+            "rdfs:label": "Back",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NotApplicable"
-                },
+                    "@id": "bts:BodyPart"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "back",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Iliacspine",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Iliacspine",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SporadicSchwannoma"
+                    "@id": "bts:BodyPart"
                 }
             ],
-            "sms:displayName": "diagnosis",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "iliac spine",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BodyPart",
+            "@id": "bts:Spine",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Sample location referring to a named area of the body, inclusive of gross anatomical structures and organ parts. ",
-            "rdfs:label": "BodyPart",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Spine",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:BodyPart"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
+            "sms:displayName": "spine",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Shoulder",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Shoulder",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Head"
-                },
+                    "@id": "bts:BodyPart"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "shoulder",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Scapula",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Scapula",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Neck"
-                },
-                {
-                    "@id": "bts:Scalp"
-                },
-                {
-                    "@id": "bts:Leg"
-                },
-                {
-                    "@id": "bts:Pelvis"
-                },
-                {
-                    "@id": "bts:Mesentery"
-                },
-                {
-                    "@id": "bts:Axilla"
-                },
-                {
-                    "@id": "bts:Acetabulum"
-                },
-                {
-                    "@id": "bts:Forearm"
-                },
-                {
-                    "@id": "bts:Muscle"
-                },
-                {
-                    "@id": "bts:Finger"
-                },
-                {
-                    "@id": "bts:Thoracicspine"
-                },
-                {
-                    "@id": "bts:Groin"
-                },
-                {
-                    "@id": "bts:Back"
-                },
-                {
-                    "@id": "bts:Iliacspine"
-                },
-                {
-                    "@id": "bts:Spine"
-                },
-                {
-                    "@id": "bts:Shoulder"
-                },
-                {
-                    "@id": "bts:Scapula"
-                },
-                {
-                    "@id": "bts:Lymphnode"
-                },
-                {
-                    "@id": "bts:Kidney"
-                },
-                {
-                    "@id": "bts:Skin"
-                },
-                {
-                    "@id": "bts:Mammarygland"
-                },
-                {
-                    "@id": "bts:Nerves"
-                },
-                {
-                    "@id": "bts:Brain"
-                },
-                {
-                    "@id": "bts:Blood"
-                },
-                {
-                    "@id": "bts:Breast"
-                },
-                {
-                    "@id": "bts:Colon"
-                },
-                {
-                    "@id": "bts:Lung"
-                },
-                {
-                    "@id": "bts:Liver"
-                },
-                {
-                    "@id": "bts:Prostate"
-                },
-                {
-                    "@id": "bts:Pancreas"
-                },
-                {
-                    "@id": "bts:Ovary"
-                },
-                {
-                    "@id": "bts:Spleen"
-                },
-                {
-                    "@id": "bts:Bonemarrow"
-                },
-                {
-                    "@id": "bts:BursaOfFabricius"
-                },
-                {
-                    "@id": "bts:Nose"
+                    "@id": "bts:BodyPart"
                 }
             ],
-            "sms:displayName": "bodyPart",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "scapula",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Organ",
+            "@id": "bts:Schwanncellprecursor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues. An organ is part of an anatomic system or a body region.",
-            "rdfs:label": "Organ",
+            "rdfs:comment": "A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19.",
+            "rdfs:label": "Schwanncellprecursor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Lymphnode"
-                },
-                {
-                    "@id": "bts:Kidney"
-                },
-                {
-                    "@id": "bts:Skin"
-                },
-                {
-                    "@id": "bts:Mammarygland"
-                },
-                {
-                    "@id": "bts:Nerves"
-                },
-                {
-                    "@id": "bts:Brain"
-                },
-                {
-                    "@id": "bts:Blood"
-                },
-                {
-                    "@id": "bts:Breast"
-                },
-                {
-                    "@id": "bts:Colon"
-                },
-                {
-                    "@id": "bts:Lung"
-                },
-                {
-                    "@id": "bts:Liver"
-                },
-                {
-                    "@id": "bts:Prostate"
-                },
-                {
-                    "@id": "bts:Pancreas"
-                },
-                {
-                    "@id": "bts:Ovary"
-                },
-                {
-                    "@id": "bts:Spleen"
-                },
-                {
-                    "@id": "bts:Bonemarrow"
-                },
-                {
-                    "@id": "bts:BursaOfFabricius"
-                },
-                {
-                    "@id": "bts:Nose"
-                },
+            "sms:displayName": "Schwann cell precursor",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:B-lymphocytes",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A lymphocyte of B lineage with the phenotype CD19-positive and surface immunoglobulin-positive.",
+            "rdfs:label": "B-lymphocytes",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Eye"
+                    "@id": "bts:CellType"
                 }
             ],
-            "sms:displayName": "organ",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "B-lymphocytes",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IndividualIdSource",
+            "@id": "bts:Embryonicstemcells",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Database or repository to which individual ID maps",
-            "rdfs:label": "IndividualIdSource",
+            "rdfs:comment": "Embryonic stem (ES) cells are cells derived from the inner cell mass of the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent.",
+            "rdfs:label": "Embryonicstemcells",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "individualIdSource",
+            "sms:displayName": "Embryonic stem cells",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tissue",
+            "@id": "bts:IPSC",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A tissue is a mereologically maximal collection of cells that together perform physiological function.",
-            "rdfs:label": "Tissue",
+            "rdfs:comment": "Induced pluripotent stem cells (iPS cells or iPSCs) are a type of pluripotent stem cell artificially derived from a non-pluripotent cell.",
+            "rdfs:label": "IPSC",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Nervetissue"
-                },
+            "sms:displayName": "iPSC",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IPSC-derivedtelencephalicorganoids",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "three-dimensional neural cultures (organoids) derived from induced pluripotent stem cells.",
+            "rdfs:label": "IPSC-derivedtelencephalicorganoids",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Opticnerve"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "iPSC-derived telencephalic organoids",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:GABAergicneurons",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A neuron that uses GABA as a vesicular neurotransmitter.",
+            "rdfs:label": "GABAergicneurons",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Serum"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "GABAergic neurons",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Monocytes",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.",
+            "rdfs:label": "Monocytes",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Plasma"
-                },
-                {
-                    "@id": "bts:Splenocyte"
-                },
-                {
-                    "@id": "bts:Blood"
-                },
-                {
-                    "@id": "bts:Primarytumor"
-                },
-                {
-                    "@id": "bts:Embryonictissue"
-                },
-                {
-                    "@id": "bts:Meninges"
-                },
-                {
-                    "@id": "bts:Bonemarrow"
-                },
-                {
-                    "@id": "bts:BuccalMucosa"
-                },
-                {
-                    "@id": "bts:DorsalRootGanglion"
-                },
-                {
-                    "@id": "bts:Unspecified"
-                },
-                {
-                    "@id": "bts:Wholebrain"
-                },
-                {
-                    "@id": "bts:BuffyCoat"
-                },
-                {
-                    "@id": "bts:Cerebralcortex"
-                },
-                {
-                    "@id": "bts:Sciaticnerve"
-                },
-                {
-                    "@id": "bts:Connectivetissue"
-                },
-                {
-                    "@id": "bts:Tumor-adjacentnormal"
-                },
-                {
-                    "@id": "bts:PDXtissue"
-                },
-                {
-                    "@id": "bts:CDXtissue"
-                },
-                {
-                    "@id": "bts:Metastatic/recurrenttumor"
-                },
-                {
-                    "@id": "bts:Recurrenttumor"
-                },
-                {
-                    "@id": "bts:Metastatictumor"
-                },
-                {
-                    "@id": "bts:Organoid"
-                },
-                {
-                    "@id": "bts:Spheroid"
-                },
-                {
-                    "@id": "bts:Microtissue"
-                },
-                {
-                    "@id": "bts:Retina"
+                    "@id": "bts:CellType"
                 }
             ],
-            "sms:displayName": "tissue",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "monocytes",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IsCellLine",
+            "@id": "bts:Microglia",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Whether or not sample source is a cell line (Yes; No)",
-            "rdfs:label": "IsCellLine",
+            "rdfs:comment": "The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system.",
+            "rdfs:label": "Microglia",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Yes"
-                },
-                {
-                    "@id": "bts:No"
-                }
-            ],
-            "sms:displayName": "isCellLine",
+            "sms:displayName": "microglia",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IsPrimaryCell",
+            "@id": "bts:Macrophages",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Whether or not cellType is primary (Yes; No)",
-            "rdfs:label": "IsPrimaryCell",
+            "rdfs:comment": "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.",
+            "rdfs:label": "Macrophages",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Yes"
-                },
-                {
-                    "@id": "bts:No"
-                }
-            ],
-            "sms:displayName": "isPrimaryCell",
+            "sms:displayName": "macrophages",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CellType",
+            "@id": "bts:Astrocytes",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A cell type is a distinct morphological or functional form of cell.",
-            "rdfs:label": "CellType",
+            "rdfs:comment": "Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with end-feet which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier.",
+            "rdfs:label": "Astrocytes",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Schwanncellprecursor"
-                },
-                {
-                    "@id": "bts:B-lymphocytes"
-                },
-                {
-                    "@id": "bts:Embryonicstemcells"
-                },
-                {
-                    "@id": "bts:IPSC"
-                },
-                {
-                    "@id": "bts:IPSC-derivedtelencephalicorganoids"
-                },
-                {
-                    "@id": "bts:GABAergicneurons"
-                },
-                {
-                    "@id": "bts:Monocytes"
-                },
-                {
-                    "@id": "bts:Microglia"
-                },
-                {
-                    "@id": "bts:Macrophages"
-                },
-                {
-                    "@id": "bts:Astrocytes"
-                },
-                {
-                    "@id": "bts:SH-SY5Y"
-                },
-                {
-                    "@id": "bts:GLUtamatergicneurons"
-                },
-                {
-                    "@id": "bts:NeuN+"
-                },
-                {
-                    "@id": "bts:NeuN-"
-                },
-                {
-                    "@id": "bts:Epithelial"
-                },
-                {
-                    "@id": "bts:Epithelial-like"
-                },
-                {
-                    "@id": "bts:Fibroblast"
-                },
-                {
-                    "@id": "bts:Round"
-                },
-                {
-                    "@id": "bts:Lymphoblast"
-                },
-                {
-                    "@id": "bts:CD8+T-Cells"
-                },
-                {
-                    "@id": "bts:Arachnoid"
-                },
-                {
-                    "@id": "bts:Meningioma"
-                },
-                {
-                    "@id": "bts:Schwannoma"
-                },
-                {
-                    "@id": "bts:Oligodendrocyte"
-                },
-                {
-                    "@id": "bts:Schwann"
-                },
-                {
-                    "@id": "bts:IPSC-derivedneuron"
-                },
-                {
-                    "@id": "bts:IPSC-derivedglia"
-                },
-                {
-                    "@id": "bts:IPSC-derivedastrocytes"
-                },
-                {
-                    "@id": "bts:Monocyte-derivedmicroglia"
-                },
-                {
-                    "@id": "bts:IPSC-derivedneuronalprogenitorcell"
-                },
-                {
-                    "@id": "bts:CD138+"
-                },
-                {
-                    "@id": "bts:CNON"
-                },
-                {
-                    "@id": "bts:Teratoma"
-                },
-                {
-                    "@id": "bts:CulturedMullerglia"
-                },
-                {
-                    "@id": "bts:DRG/nerverootneurospherecell"
-                }
-            ],
-            "sms:displayName": "cellType",
+            "sms:displayName": "astrocytes",
             "sms:required": "sms:false",
-            "sms:validationRules": [
-                "list like"
-            ]
+            "sms:validationRules": []
         },
         {
-            "@id": "bts:IsMultiIndividual",
+            "@id": "bts:SH-SY5Y",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Whether or not a file has data for multiple individuals (Yes; No)",
-            "rdfs:label": "IsMultiIndividual",
+            "rdfs:comment": "Human neuroblastoma clonal subline of the neuroepithelioma cell line SK-N-SH that had been established in 1970 from the bone marrow biopsy of a 4-year-old girl with metastatic neuroblastoma.",
+            "rdfs:label": "SH-SY5Y",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Yes"
-                },
-                {
-                    "@id": "bts:No"
-                }
-            ],
-            "sms:displayName": "isMultiIndividual",
-            "sms:required": "sms:true",
+            "sms:displayName": "SH-SY5Y",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IsMultiSpecimen",
+            "@id": "bts:GLUtamatergicneurons",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Whether or not a file has data for multiple specimens (Yes; No)",
-            "rdfs:label": "IsMultiSpecimen",
+            "rdfs:comment": "Have Glutamate receptors, which are synaptic receptors located primarily on the membranes of neuronal cells. Glutamate (the conjugate base of glutamic acid) is abundant in the human body, but particularly in the nervous system and especially prominent in the human brain.",
+            "rdfs:label": "GLUtamatergicneurons",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Yes"
-                },
+            "sms:displayName": "GLUtamatergic neurons",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:NeuN+",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Is a neuronal nuclear antigen that is commonly used as a biomarker for neurons and NeuN immunoreactivity has been widely used to identify neurons in tissue culture to measure the neuron(positive)/glia(negative) ratio in brain regions.",
+            "rdfs:label": "NeuN+",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:No"
+                    "@id": "bts:CellType"
                 }
             ],
-            "sms:displayName": "isMultiSpecimen",
-            "sms:required": "sms:true",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "NeuN+",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sex",
+            "@id": "bts:NeuN-",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Phenotypic expression of chromosomal makeup that defines a study subject as male, female, or other.",
-            "rdfs:label": "Sex",
+            "rdfs:comment": "Is a neuronal nuclear antigen that is commonly used as a biomarker for neurons and NeuN immunoreactivity has been widely used to identify neurons in tissue culture to measure the neuron(positive)/glia(negative) ratio in brain regions.",
+            "rdfs:label": "NeuN-",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Male"
-                },
-                {
-                    "@id": "bts:Female"
-                },
+            "sms:displayName": "NeuN-",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Epithelial",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Somatic cells that cover the surface of the body and line its cavities.",
+            "rdfs:label": "Epithelial",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Unknown"
+                    "@id": "bts:CellType"
                 }
             ],
-            "sms:displayName": "sex",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "epithelial",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Species",
+            "@id": "bts:Epithelial-like",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The name of a species (typically a taxonomic group) of organism.",
-            "rdfs:label": "Species",
+            "rdfs:comment": "In cell morphology, epithelial-like cells are polygonal in shape with more regular dimensions, and grow attached to a substrate in discrete patches.",
+            "rdfs:label": "Epithelial-like",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Homosapiens"
-                },
-                {
-                    "@id": "bts:Musmusculus"
-                },
-                {
-                    "@id": "bts:Musmusculus(humanized)"
-                },
-                {
-                    "@id": "bts:Rattusnorvegicus"
-                },
-                {
-                    "@id": "bts:Drosophilamelanogaster"
-                },
-                {
-                    "@id": "bts:Rhesusmacaque"
-                },
-                {
-                    "@id": "bts:Pantroglodytes"
-                },
-                {
-                    "@id": "bts:Gallusgallus"
-                },
-                {
-                    "@id": "bts:Susscrofa"
-                },
-                {
-                    "@id": "bts:Oryctolaguscuniculus"
-                },
+            "sms:displayName": "epithelial-like",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Fibroblast",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.",
+            "rdfs:label": "Fibroblast",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Daniorerio"
+                    "@id": "bts:CellType"
                 }
             ],
-            "sms:displayName": "species",
-            "sms:required": "sms:true",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "fibroblast",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IndividualID",
+            "@id": "bts:Round",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A unique identifier (non-PII) that represents the individual from which the data came. This could be a patient or animal ID.",
-            "rdfs:label": "IndividualID",
+            "rdfs:comment": "A phenotype observation at the level of the cell shape where the cell is round",
+            "rdfs:label": "Round",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "individualID",
+            "sms:displayName": "round",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Sex"
-                },
-                {
-                    "@id": "bts:Age"
-                },
-                {
-                    "@id": "bts:AgeUnit"
-                },
-                {
-                    "@id": "bts:Species"
-                },
-                {
-                    "@id": "bts:Diagnosis"
-                },
-                {
-                    "@id": "bts:Nf1Genotype"
-                },
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Lymphoblast",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Often referred to as a blast cell. Unlike other usages of the suffix -blast a lymphoblast is a further differentiation of a lymphocyte, T- or B-, occasioned by an antigenic stimulus. The lymphoblast usually develops by enlargement of a lymphocyte, active re-entry to the S phase of the cell cycle, mitogenesis and production of much m-RNA and ribosomes.",
+            "rdfs:label": "Lymphoblast",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:CellType"
                 }
             ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "lymphoblast",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ParentSpecimenID",
+            "@id": "bts:CD8+T-Cells",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A unique identifier (non-PII) that represents the parent specimen (sample) from which the data came from, e.g. the single parent tumor. The parentSpecimenIDcan be the same as specimenID when there is no subsectioning.",
-            "rdfs:label": "ParentSpecimenID",
+            "rdfs:comment": "Is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.",
+            "rdfs:label": "CD8+T-Cells",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "parentSpecimenID",
+            "sms:displayName": "CD8+ T-Cells",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:SpecimenID"
-                },
-                {
-                    "@id": "bts:AliquotID"
-                },
-                {
-                    "@id": "bts:Organ"
-                },
-                {
-                    "@id": "bts:Tissue"
-                },
-                {
-                    "@id": "bts:IsCellLine"
-                },
-                {
-                    "@id": "bts:IsPrimaryCell"
-                },
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Arachnoid",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "An arachnoid mater is a delicate membrane that encloses the spinal cord and brain and lies between the pia mater and dura mater.",
+            "rdfs:label": "Arachnoid",
+            "rdfs:subClassOf": [
                 {
                     "@id": "bts:CellType"
-                },
-                {
-                    "@id": "bts:TumorType"
-                },
-                {
-                    "@id": "bts:SpecimenPreparationMethod"
-                },
-                {
-                    "@id": "bts:ModelSystemName"
                 }
             ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "arachnoid",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SpecimenID",
+            "@id": "bts:Meningioma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A unique identifier (non-PII) that represents the subspecimen (subsample) from which the data came, e.g. an ID that distinguishes between different parts of the same parent tumor specimen. This can be the A A unique identifier (non-PII) that represents the",
-            "rdfs:label": "SpecimenID",
+            "rdfs:comment": "A central nervous system cancer tissue that are manifested in the central nervous system and arise from the arachnoid 'cap' cells of the arachnoid villi in the meninges.",
+            "rdfs:label": "Meningioma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "specimenID",
+            "sms:displayName": "meningioma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SpecimenIDSource",
+            "@id": "bts:Schwannoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Optional annotation describing where the specimen ID source derived from, e.g. the biobank providing samples or a providing lab.",
-            "rdfs:label": "SpecimenIDSource",
+            "rdfs:comment": "A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves.",
+            "rdfs:label": "Schwannoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "specimenIDSource",
+            "sms:displayName": "schwannoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AliquotID",
+            "@id": "bts:Oligodendrocyte",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A unique identifier (non-PII) that represents the aliquots used for e.g. replicate runs. This is linked to the specimenID. ",
-            "rdfs:label": "AliquotID",
+            "rdfs:comment": "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.",
+            "rdfs:label": "Oligodendrocyte",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "aliquotID",
+            "sms:displayName": "oligodendrocyte",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ModelSystemName",
+            "@id": "bts:Schwann",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A group of presumed common ancestry with clear-cut physiological but usually not morphological distinctions such as an animal model or cell line. EXAMPLE(S):  HEK293T (cell line), Minnesota5 (swine strain), DXL (poultry strain), RB51 (vaccine strain of Brucella abortus)",
-            "rdfs:label": "ModelSystemName",
+            "rdfs:comment": "Schwann cells are a variety of glial cell that keep peripheral nerve fibres (both myelinated and unmyelinated) alive.",
+            "rdfs:label": "Schwann",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Neuro"
+                    "@id": "bts:CellType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:C57BL/6J"
-                },
-                {
-                    "@id": "bts:NODscidgamma"
-                },
-                {
-                    "@id": "bts:B6;129S2-Trp53tm1TyjNf1tm1Tyj/J"
-                },
-                {
-                    "@id": "bts:B6;129-Trp53tm1TyjNf1tm1TyjSuz12Gt(Betageo)1Khe/KcichJ"
-                },
-                {
-                    "@id": "bts:B6.129S2-Nf1tm1Tyj/J"
-                },
-                {
-                    "@id": "bts:B6.129S1-Nf1tm1Cbr/J"
-                },
-                {
-                    "@id": "bts:B6.129(Cg)-Nf1tm1Par/J"
-                },
-                {
-                    "@id": "bts:HiPSC-SCP"
-                },
-                {
-                    "@id": "bts:HiPSC"
-                },
-                {
-                    "@id": "bts:JHU2-103-CL"
-                },
-                {
-                    "@id": "bts:JHU2-002-CL"
-                },
-                {
-                    "@id": "bts:JHU2-079-CL"
-                },
-                {
-                    "@id": "bts:JHU2-103-PDX"
-                },
-                {
-                    "@id": "bts:JHU2-002-PDX"
-                },
-                {
-                    "@id": "bts:JHU2-079-PDX"
-                },
-                {
-                    "@id": "bts:Humanforeskinfibroblasts"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF05.5"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF05.5(Mixedclones)"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipn06.2A"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF95.11bC/T"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF95.6"
-                },
-                {
-                    "@id": "bts:HTERTSCipn02.8"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipnNF95.11c"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF95.11bC"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipnNF09.4"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF04.4"
-                },
-                {
-                    "@id": "bts:HTERTNF1sipnNF95.12B"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF00.6"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipNF03.3"
-                },
-                {
-                    "@id": "bts:HTERTNF1ipn02.32λ"
-                },
-                {
-                    "@id": "bts:HTERTSCipn02.8"
-                },
-                {
-                    "@id": "bts:SZ-NF1"
-                },
-                {
-                    "@id": "bts:SZ-NF2"
-                },
-                {
-                    "@id": "bts:SZ-NF4"
-                },
-                {
-                    "@id": "bts:NF1"
-                },
-                {
-                    "@id": "bts:Lis42NF11N"
-                },
-                {
-                    "@id": "bts:Lis47NF12N"
-                },
-                {
-                    "@id": "bts:ST88-14"
-                },
-                {
-                    "@id": "bts:SNF96.2"
-                },
-                {
-                    "@id": "bts:SNF02.2"
-                },
-                {
-                    "@id": "bts:SNF94.3"
-                },
+            "sms:displayName": "schwann",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IPSC-derivedneuron",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "IPSC-derivedneuron",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:GM11602"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "iPSC-derived neuron",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IPSC-derivedglia",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "IPSC-derivedglia",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:GM11601"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "iPSC-derived glia",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IPSC-derivedastrocytes",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "IPSC-derivedastrocytes",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:KCL024"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "iPSC-derived astrocytes",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Monocyte-derivedmicroglia",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Monocyte-derivedmicroglia",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:KCL025"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "monocyte-derived microglia",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IPSC-derivedneuronalprogenitorcell",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "IPSC-derivedneuronalprogenitorcell",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:5PNFTdiPSsvPM6"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "iPSC-derived neuronal progenitor cell",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:CD138+",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "CD138+",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:5PNFTdiPSsvMM4"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "CD138+",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:CNON",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Cultured Neuronal cells derived from Olfactory Neuroepithelium",
+            "rdfs:label": "CNON",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:7PNFSiPSrvPM12"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "CNON",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Teratoma",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach",
+            "rdfs:label": "Teratoma",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:6PNFSiPSrvPM2"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "teratoma",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:CulturedMullerglia",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. [ http://www.ncbi.nlm.nih.gov/pubmed/21911394 GOC : NV ]",
+            "rdfs:label": "CulturedMullerglia",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:3PNFSiPSsvMM11"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "cultured Muller glia",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:DRG/nerverootneurospherecell",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Dorsal root ganglia/nerve root neurosphere cells (DNSCs) are cultured from embryonic DRGs/nerve roots and have been used in in vitro sphere assays to study the origin of para-spinal neurofibromas. See reference PMC4254535",
+            "rdfs:label": "DRG/nerverootneurospherecell",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:3PNFFiPSsvPM2"
-                },
+                    "@id": "bts:CellType"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "DRG/nerve root neurosphere cell",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Neurofibromatosistype1",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "(NF1) - A disease characterized by patches of skin pigmentation (cafe-au-lait spots), Lisch nodules of the iris, tumors in the peripheral nervous system and fibromatous skin tumors. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors.",
+            "rdfs:label": "Neurofibromatosistype1",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NCC-MPNST5-C1"
-                },
+                    "@id": "bts:Diagnosis"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Neurofibromatosis type 1",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Neurofibromatosistype2",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "(NF2) - Genetic disorder characterized by bilateral vestibular schwannomas (formerly called acoustic neuromas), schwannomas of other cranial and peripheral nerves, meningiomas, and ependymomas. It is inherited in an autosomal dominant fashion with full penetrance.",
+            "rdfs:label": "Neurofibromatosistype2",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NCC-MPNST3-C1"
-                },
+                    "@id": "bts:Diagnosis"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Neurofibromatosis type 2",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Schwannomatosis",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A rare genetic disorder characterized by the presence of multiple schwannomas.",
+            "rdfs:label": "Schwannomatosis",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NCC-MPNST4-C1"
-                },
+                    "@id": "bts:Diagnosis"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Schwannomatosis",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:NotApplicable",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "An NF diagnosis (e.g. NF1, NF2, or Schwannomatosis) does not apply here.",
+            "rdfs:label": "NotApplicable",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NCC-MPNST3-X2-C1"
-                },
+                    "@id": "bts:Diagnosis"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Not Applicable",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:SporadicSchwannoma",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A",
+            "rdfs:label": "SporadicSchwannoma",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NCC-MPNST2-C1"
-                },
+                    "@id": "bts:Diagnosis"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Sporadic Schwannoma",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Cancer",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Cancer",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:STS-26T"
-                },
+                    "@id": "schema:Thing"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "cancer",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Neuro",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Neuro",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:YST-1"
-                },
+                    "@id": "schema:Thing"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "neuro",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Neurofibromatosis",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Neurofibromatosis",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:90-8"
-                },
+                    "@id": "schema:Thing"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "neurofibromatosis",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:-/-",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Homozygous deletion or mutation of NF1.",
+            "rdfs:label": "-/-",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:S520"
-                },
+                    "@id": "bts:Nf1Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "-/-",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:+/-",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Heterozygous deletion or mutation",
+            "rdfs:label": "+/-",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:S462"
-                },
+                    "@id": "bts:Nf1Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "+/-",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:+/+",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Homozygous wildtype",
+            "rdfs:label": "+/+",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:S462.TY"
-                },
+                    "@id": "bts:Nf1Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "+/+",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Unknown",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "unknown",
+            "rdfs:label": "Unknown",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Sc93.1"
-                },
+                    "@id": "bts:Nf1Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Unknown",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:-/-",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Homozygous deletion or mutation of NF2.",
+            "rdfs:label": "-/-",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Fb93.1"
-                },
+                    "@id": "bts:Nf2Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "-/-",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:+/-",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Heterozygous deletion or mutation",
+            "rdfs:label": "+/-",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:JH-2-002-CL"
-                },
+                    "@id": "bts:Nf2Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "+/-",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:+/+",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Homozygous wild type",
+            "rdfs:label": "+/+",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:JH-2-079-CL"
-                },
+                    "@id": "bts:Nf2Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "+/+",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Unknown",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "unknown",
+            "rdfs:label": "Unknown",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:JH-2-103-CL"
-                },
+                    "@id": "bts:Nf2Genotype"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Unknown",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Polymericnanoparticles",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Polymeric nanoparticles (PNPs) are solid and spherical (in most cases) structures prepared from natural or synthetic polymers with drug delivery being known to be one of the most important biomedical applications (reference: Hirvonen et al., Nanoengineered Biomaterials for Advanced Drug Delivery, 2020)",
+            "rdfs:label": "Polymericnanoparticles",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:IcNF00.10a"
-                },
+                    "@id": "schema:Thing"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Polymeric nanoparticles",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:DNA",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "DNA (deoxyribonucleic acid) is a polymer of nucleotides and is the genetic material in organisms and some viruses.",
+            "rdfs:label": "DNA",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CNF00.10a"
-                },
+                    "@id": "schema:Thing"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "DNA",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:C57BL/6J",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "C57BL/6 is the most widely used inbred strain. It is commonly used as a general purpose strain and background strain for the generation of congenics carrying both spontaneous and induced mutations.",
+            "rdfs:label": "C57BL/6J",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:IcNF97.2a"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "C57BL/6J",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:NODscidgamma",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "These mice are most often referred to using their branded name NSG™ and are extremely immunodeficient.",
+            "rdfs:label": "NODscidgamma",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CNF97.2a"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "NOD scid gamma",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:NRG",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Extremely immunodeficient mice with a targeted knockout mutation in recombination activating gene 1 (Rag1) and a complete null allele of the IL2 receptor common gamma chain.",
+            "rdfs:label": "NRG",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:IcNF97.2b"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "NRG",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:B6;129S2-Trp53tm1TyjNf1tm1Tyj/J",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "B6;129S2-Trp53tm1TyjNf1tm1Tyj/J",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CNF97.2b"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "B6;129S2-Trp53tm1Tyj Nf1tm1Tyj/J",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:B6;129-Trp53tm1TyjNf1tm1TyjSuz12Gt(Betageo)1Khe/KcichJ",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "B6;129-Trp53tm1TyjNf1tm1TyjSuz12Gt(Betageo)1Khe/KcichJ",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:IcNF98.4d"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "B6;129-Trp53tm1Tyj Nf1tm1Tyj Suz12Gt(Betageo)1Khe/KcichJ",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:B6.129S2-Nf1tm1Tyj/J",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "B6.129S2-Nf1tm1Tyj/J",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CNF98.4d"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "B6.129S2-Nf1tm1Tyj/J",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:B6.129S1-Nf1tm1Cbr/J",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "B6.129S1-Nf1tm1Cbr/J",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:I28cNF"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "B6.129S1-Nf1tm1Cbr/J",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:B6.129(Cg)-Nf1tm1Par/J",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "B6.129(Cg)-Nf1tm1Par/J",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:28cNF"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "B6.129(Cg)-Nf1tm1Par/J",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HiPSC-SCP",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Schwann cell precursor iPSCs",
+            "rdfs:label": "HiPSC-SCP",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:IcNF04.9a"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hiPSC-SCP",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HiPSC",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "human iPSCs",
+            "rdfs:label": "HiPSC",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CNF04.9a"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hiPSC",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:JHU2-103-CL",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "An MPNST cell line derived from JHU NF1 Biobank tumor specimen JHU 2-103.",
+            "rdfs:label": "JHU2-103-CL",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:IcNF98.4c"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "JHU 2-103-CL",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:JHU2-002-CL",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "An MPNST cell line derived from JHU NF1 Biobank tumor specimen JHU 2-002.",
+            "rdfs:label": "JHU2-002-CL",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CNF98.4c"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "JHU 2-002-CL",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:JHU2-079-CL",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "An MPNST cell line derived from JHU NF1 Biobank tumor specimen JHU 2-079.",
+            "rdfs:label": "JHU2-079-CL",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2-/-SchwannSC(mouse)(PMID26554010)"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "JHU 2-079-CL",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:JHU2-103-PDX",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A PDX model derived from JHU NF1 Biobank tumor specimen JHU 2-103.",
+            "rdfs:label": "JHU2-103-PDX",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SC4[Mouseschwannoma]"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "JHU 2-103-PDX",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:JHU2-002-PDX",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A PDX model derived from JHU NF1 Biobank tumor specimen JHU 2-002.",
+            "rdfs:label": "JHU2-002-PDX",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:AC007-hTERT"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "JHU 2-002-PDX",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:JHU2-079-PDX",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A PDX model derived from JHU NF1 Biobank tumor specimen JHU 2-079.",
+            "rdfs:label": "JHU2-079-PDX",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NF2-/-AC007-hTERT"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "JHU 2-079-PDX",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF05.5",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTNF1ipNF05.5",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Ben-Men-1"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF05.5",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF05.5(Mixedclones)",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTNF1ipNF05.5(Mixedclones)",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:M3MPNST"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF05.5 (Mixed clones)",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipn06.2A",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTNF1ipn06.2A",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:NRG"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
-            "sms:displayName": "modelSystemName",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipn06.2 A",
             "sms:required": "sms:false",
-            "sms:validationRules": [
-                "list like"
-            ]
+            "sms:validationRules": []
         },
         {
-            "@id": "bts:Nf2Genotype",
+            "@id": "bts:HTERTNF1ipNF95.11bC/T",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Genotype of NF2 gene in the biospecimen from which the data were derived, if known",
-            "rdfs:label": "Nf2Genotype",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTNF1ipNF95.11bC/T",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Neurofibromatosis"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
+            "sms:displayName": "hTERT NF1 ipNF95.11b C/T",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF95.6",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTNF1ipNF95.6",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:-/-"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF95.6",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTSCipn02.8",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTSCipn02.8",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:+/-"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT SC ipn02.8",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipnNF95.11c",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "plexiform neurofibroma cell line",
+            "rdfs:label": "HTERTNF1ipnNF95.11c",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:+/+"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipnNF95.11c",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF95.11bC",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1ipNF95.11bC",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:+/?"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF95.11b C",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipnNF09.4",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1ipnNF09.4",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:-/?"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipnNF09.4",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF04.4",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1ipNF04.4",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Unknown"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
-            "sms:displayName": "nf2Genotype",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF04.4",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Nf1Genotype",
+            "@id": "bts:HTERTNF1sipnNF95.12B",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Genotype of NF1 gene in the biospecimen from which the data were derived, if known",
-            "rdfs:label": "Nf1Genotype",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1sipnNF95.12B",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Neurofibromatosis"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
+            "sms:displayName": "hTERT NF1 sipnNF95.12B",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF00.6",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1ipNF00.6",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:-/-"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF00.6",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipNF03.3",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1ipNF03.3",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:+/-"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipNF03.3",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTNF1ipn02.32λ",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTNF1ipn02.32λ",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:+/+"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT NF1 ipn02.3 2λ",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:HTERTSCipn02.8",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "HTERTSCipn02.8",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:+/?"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "hTERT SC ipn02.8",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:SZ-NF1",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SZ-NF1",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:-/?"
-                },
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "SZ-NF1",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:SZ-NF2",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SZ-NF2",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Unknown"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
-            "sms:displayName": "nf1Genotype",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "SZ-NF2",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SpecimenPreparationMethod",
+            "@id": "bts:SZ-NF4",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Term that represents preservation of the sample before usage in, e.g. sequencing",
-            "rdfs:label": "SpecimenPreparationMethod",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SZ-NF4",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Ngs"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Freshcollected"
-                },
-                {
-                    "@id": "bts:Flashfrozen"
-                },
-                {
-                    "@id": "bts:FFPE"
-                },
-                {
-                    "@id": "bts:Cryopreserved"
-                },
-                {
-                    "@id": "bts:OCT"
-                },
-                {
-                    "@id": "bts:RNAlater"
-                },
-                {
-                    "@id": "bts:Formalin-fixed"
-                },
-                {
-                    "@id": "bts:Ethanol"
-                },
-                {
-                    "@id": "bts:Viablyfrozen"
-                }
-            ],
-            "sms:displayName": "specimenPreparationMethod",
+            "sms:displayName": "SZ-NF4",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Age",
+            "@id": "bts:NF1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A numeric value representing age of the individual. Use with ageUnit.",
-            "rdfs:label": "Age",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NF1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "age",
+            "sms:displayName": "NF1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:AgeUnit"
-                }
-            ],
-            "sms:validationRules": [
-                "num"
-            ]
+            "sms:validationRules": []
         },
         {
-            "@id": "bts:AgeUnit",
+            "@id": "bts:Lis42NF11N",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A time unit that can be used with a given age value, e.g. years.",
-            "rdfs:label": "AgeUnit",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Lis42NF11N",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Days"
-                },
-                {
-                    "@id": "bts:Months"
-                },
-                {
-                    "@id": "bts:Years"
-                }
-            ],
-            "sms:displayName": "ageUnit",
+            "sms:displayName": "Lis42_NF1_1N",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BioSampleUsed",
+            "@id": "bts:Lis47NF12N",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The biosample used.",
-            "rdfs:label": "BioSampleUsed",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Lis47NF12N",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bioSampleUsed",
+            "sms:displayName": "Lis47_NF1_2N",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IsXenograft",
+            "@id": "bts:ST88-14",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Whether or not sample source is a xenograft (Yes; No)",
-            "rdfs:label": "IsXenograft",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "ST88-14",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Yes"
-                },
-                {
-                    "@id": "bts:No"
-                }
-            ],
-            "sms:displayName": "isXenograft",
-            "sms:required": "sms:true",
+            "sms:displayName": "ST88-14",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Rawcounts",
+            "@id": "bts:SNF96.2",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The number or amount of something.",
-            "rdfs:label": "Rawcounts",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SNF96.2",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "raw counts",
+            "sms:displayName": "sNF96.2",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Volume",
+            "@id": "bts:SNF02.2",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The amount of three dimensional space occupied by an object or the capacity of a space or container.",
-            "rdfs:label": "Volume",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SNF02.2",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Volume",
+            "sms:displayName": "sNF02.2",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Weight",
+            "@id": "bts:SNF94.3",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The vertical force exerted by a mass as a result of gravity.",
-            "rdfs:label": "Weight",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "SNF94.3",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Weight",
+            "sms:displayName": "sNF94.3",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PharmacokineticStudy",
+            "@id": "bts:GM11602",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.",
-            "rdfs:label": "PharmacokineticStudy",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "GM11602",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Pharmacokinetic Study",
+            "sms:displayName": "GM11602",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GenomicVariants",
+            "@id": "bts:GM11601",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Genomic alterations, including single nucleotide polymorphisms, short indels and structural variants. Use more specific term if possible, esp. if data is only of one specific subset.",
-            "rdfs:label": "GenomicVariants",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "GM11601",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "genomicVariants",
+            "sms:displayName": "GM11601",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AlignedReads",
+            "@id": "bts:KCL024",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Aligned reads output from alignment workflows",
-            "rdfs:label": "AlignedReads",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "KCL024",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "AlignedReads",
+            "sms:displayName": "KCL024",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SomaticVariants",
+            "@id": "bts:KCL025",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Called somatic variants",
-            "rdfs:label": "SomaticVariants",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "KCL025",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SomaticVariants",
+            "sms:displayName": "KCL025",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AnnotatedSomaticVariants",
+            "@id": "bts:5PNFTDiPSsvPM6",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Somatic variants annotated with some annotation workflow",
-            "rdfs:label": "AnnotatedSomaticVariants",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "5PNFTDiPSsvPM6",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "AnnotatedSomaticVariants",
+            "sms:displayName": "5PNF_TDiPSsv_PM_6",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GermlineVariants",
+            "@id": "bts:5PNFTDiPSsvMM4",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Called germline variants",
-            "rdfs:label": "GermlineVariants",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "5PNFTDiPSsvMM4",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GermlineVariants",
+            "sms:displayName": "5PNF_TDiPSsv_MM_4",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:7PNFSiPSrvPM12",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "7PNFSiPSrvPM12",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Assay"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "7PNF_SiPSrv_PM_12",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AnnotatedGermlineVariants",
+            "@id": "bts:6PNFSiPSrvPM2",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Germline variants annotated with some annotation workflow",
-            "rdfs:label": "AnnotatedGermlineVariants",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "6PNFSiPSrvPM2",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "AnnotatedGermlineVariants",
+            "sms:displayName": "6PNF_SiPSrv_PM_2",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:StructuralVariants",
+            "@id": "bts:3PNFSiPSsvMM11",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Specifically genomic variants data classified as structural variants, which may be derived from specialized variant calling workflows",
-            "rdfs:label": "StructuralVariants",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "3PNFSiPSsvMM11",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "StructuralVariants",
+            "sms:displayName": "3PNF_SiPSsv_MM_11",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Behaviorprocess",
+            "@id": "bts:3PNFFiPSsvPM2",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The action, reaction, or performance of an organism in response to external or internal stimuli.",
-            "rdfs:label": "Behaviorprocess",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "3PNFFiPSsvPM2",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "behavior process",
+            "sms:displayName": "3PNF_FiPSsv_PM_2",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Metabolomics",
+            "@id": "bts:NCC-MPNST5-C1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism.",
-            "rdfs:label": "Metabolomics",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NCC-MPNST5-C1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "metabolomics",
+            "sms:displayName": "NCC-MPNST5-C1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Image",
+            "@id": "bts:NCC-MPNST3-C1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Biological or biomedical data that has been rendered into an image.",
-            "rdfs:label": "Image",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NCC-MPNST3-C1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "image",
+            "sms:displayName": "NCC-MPNST3-C1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GeneExpression",
+            "@id": "bts:NCC-MPNST4-C1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data.",
-            "rdfs:label": "GeneExpression",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NCC-MPNST4-C1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "geneExpression",
+            "sms:displayName": "NCC-MPNST4-C1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:IsoformExpression",
+            "@id": "bts:NCC-MPNST3-X2-C1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Expression of protien isoforms formed from alternative splicings or other post-translational modifications of a single gene through RNA splicing mechanisms.",
-            "rdfs:label": "IsoformExpression",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NCC-MPNST3-X2-C1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "isoformExpression",
+            "sms:displayName": "NCC-MPNST3-X2-C1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Proteomics",
+            "@id": "bts:NCC-MPNST2-C1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Protein and peptide identification, especially in the study of whole proteomes of organisms.",
-            "rdfs:label": "Proteomics",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NCC-MPNST2-C1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "proteomics",
+            "sms:displayName": "NCC-MPNST2-C1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Kinomics",
+            "@id": "bts:STS-26T",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Kinomics is the study of protein kinases and protein kinase signaling.",
-            "rdfs:label": "Kinomics",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "STS-26T",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "kinomics",
+            "sms:displayName": "STS-26T",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DrugScreen",
+            "@id": "bts:YST-1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Information on drug sensitivity and molecular markers of drug response",
-            "rdfs:label": "DrugScreen",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "YST-1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "drugScreen",
+            "sms:displayName": "YST-1",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DrugCombinationScreen",
+            "@id": "bts:90-8",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Information on drug sensitivity of more than one compound",
-            "rdfs:label": "DrugCombinationScreen",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "90-8",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "drugCombinationScreen",
+            "sms:displayName": "90-8",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CellularPhysiology",
+            "@id": "bts:S520",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "CellularPhysiology",
+            "rdfs:label": "S520",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cellularPhysiology",
+            "sms:displayName": "S520",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ChromatinActivity",
+            "@id": "bts:S462",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Chromatin activity that allow access of condensed genomic DNA and potentially control gene expression.",
-            "rdfs:label": "ChromatinActivity",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "S462",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "chromatinActivity",
+            "sms:displayName": "S462",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SurveyData",
+            "@id": "bts:S462.TY",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A data set that contains the outcome of a survey.",
-            "rdfs:label": "SurveyData",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "S462.TY",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "surveyData",
+            "sms:displayName": "S462.TY",
             "sms:required": "sms:false",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:Assay"
-                }
-            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Network",
+            "@id": "bts:T265",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An interconnected system of things or people.",
-            "rdfs:label": "Network",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "T265",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "network",
+            "sms:displayName": "T265",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Clinical",
+            "@id": "bts:Sc93.1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Data obtained through patient examination or treatment.",
-            "rdfs:label": "Clinical",
+            "rdfs:comment": "Cell line generated by Ray Mattingly's lab.",
+            "rdfs:label": "Sc93.1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "clinical",
+            "sms:displayName": "sc93.1",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Immunoassay",
+            "@id": "bts:Fb93.1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Laboratory test involving interaction of antigens with specific antibodies.",
-            "rdfs:label": "Immunoassay",
+            "rdfs:comment": "Cell line generated by Ray Mattingly's lab.",
+            "rdfs:label": "Fb93.1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "immunoassay",
+            "sms:displayName": "Fb93.1",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Electrophysiology",
+            "@id": "bts:JH-2-002-CL",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Data generated from an electrophysiology assay.",
-            "rdfs:label": "Electrophysiology",
+            "rdfs:comment": "Cell line derived from JHU biobank individual",
+            "rdfs:label": "JH-2-002-CL",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "electrophysiology",
+            "sms:displayName": "JH-2-002-CL",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Maskimage",
+            "@id": "bts:JH-2-079-CL",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Image used as the mask for an image processing operation, such as subtraction.",
-            "rdfs:label": "Maskimage",
+            "rdfs:comment": "Cell line derived from JHU biobank individual",
+            "rdfs:label": "JH-2-079-CL",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataType"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mask image",
+            "sms:displayName": "JH-2-079-CL",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CuratedData",
+            "@id": "bts:JH-2-103-CL",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any file derived from or pertaining a manually or programatically curated data resource. Examples include: reference sequences, drug information databases, identifier maps\"\"",
-            "rdfs:label": "CuratedData",
+            "rdfs:comment": "Cell line derived from JHU biobank individual",
+            "rdfs:label": "JH-2-103-CL",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "curatedData",
+            "sms:displayName": "JH-2-103-CL",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Normalized",
+            "@id": "bts:IcNF00.10a",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A data set that is produced as the output of a normalization data transformation.",
-            "rdfs:label": "Normalized",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF00.10a).",
+            "rdfs:label": "IcNF00.10a",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataSubtype"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "normalized",
+            "sms:displayName": "icNF00.10a",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DataMatrix",
+            "@id": "bts:CNF00.10a",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A file of data containing multiple values for multiple samples.",
-            "rdfs:label": "DataMatrix",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF00.10a).",
+            "rdfs:label": "CNF00.10a",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataSubtype"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "dataMatrix",
+            "sms:displayName": "cNF00.10a",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Raw",
+            "@id": "bts:IcNF97.2a",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A data file produced by an instrument, or one with very little subsequent processing.",
-            "rdfs:label": "Raw",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF97.2a).",
+            "rdfs:label": "IcNF97.2a",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataSubtype"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "raw",
+            "sms:displayName": "icNF97.2a",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Processed",
+            "@id": "bts:CNF97.2a",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A file of data generated from running one or more bioinformatics methods on a raw file.",
-            "rdfs:label": "Processed",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF97.2a).",
+            "rdfs:label": "CNF97.2a",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataSubtype"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "processed",
+            "sms:displayName": "cNF97.2a",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Metadata",
+            "@id": "bts:IcNF97.2b",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A file of clinical, technical, or other parameters that describe a dataset.",
-            "rdfs:label": "Metadata",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF97.2b).",
+            "rdfs:label": "IcNF97.2b",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataSubtype"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "metadata",
+            "sms:displayName": "icNF97.2b",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Representative",
+            "@id": "bts:CNF97.2b",
             "@type": "rdfs:Class",
-            "rdfs:comment": "An activity that stands as an equivalent of something or results in an equivalent; typical of, or the same as, others in a larger group of people or things.",
-            "rdfs:label": "Representative",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF97.2b).",
+            "rdfs:label": "CNF97.2b",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DataSubtype"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "representative",
+            "sms:displayName": "cNF97.2b",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bashscript",
+            "@id": "bts:IcNF98.4d",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Bash Shell Script",
-            "rdfs:label": "Bashscript",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF98.4d).",
+            "rdfs:label": "IcNF98.4d",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bash script",
+            "sms:displayName": "icNF98.4d",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bedgraph",
+            "@id": "bts:CNF98.4d",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Holds a tab-delimited chromosome /start /end / datavalue dataset. The bedGraph format allows display of continuous-valued data in track format. This display type is useful for probability scores and transcriptome data",
-            "rdfs:label": "Bedgraph",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF98.4d).",
+            "rdfs:label": "CNF98.4d",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bedgraph",
+            "sms:displayName": "cNF98.4d",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Ai",
+            "@id": "bts:I28cNF",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Adobe Illustrator format",
-            "rdfs:label": "Ai",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (28NF).",
+            "rdfs:label": "I28cNF",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "ai",
+            "sms:displayName": "i28cNF",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Idx",
+            "@id": "bts:28cNF",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Idx",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (i28NF).",
+            "rdfs:label": "28cNF",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "idx",
+            "sms:displayName": "28cNF",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Idat",
+            "@id": "bts:IcNF04.9a",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Proprietary file format for (raw) BeadArray data used by genomewide profiling platforms from Illumina Inc. This format is output directly from the scanner and stores summary intensities for each probe-type on an array.",
-            "rdfs:label": "Idat",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF04.9a).",
+            "rdfs:label": "IcNF04.9a",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "idat",
+            "sms:displayName": "icNF04.9a",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bam",
+            "@id": "bts:CNF04.9a",
             "@type": "rdfs:Class",
-            "rdfs:comment": "BAM format, the binary, BGZF-formatted compressed version of SAM format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s)",
-            "rdfs:label": "Bam",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF04.9a).",
+            "rdfs:label": "CNF04.9a",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bam",
+            "sms:displayName": "cNF04.9a",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bai",
+            "@id": "bts:IcNF98.4c",
             "@type": "rdfs:Class",
-            "rdfs:comment": "BAM indexing format",
-            "rdfs:label": "Bai",
+            "rdfs:comment": "An hTERT-immortalized cutaneous neurofibroma cell line derived from a primary cell culture (cNF98.4c).",
+            "rdfs:label": "IcNF98.4c",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bai",
+            "sms:displayName": "icNF98.4c",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Excel",
+            "@id": "bts:CNF98.4c",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Microsoft Excel spreadsheet format",
-            "rdfs:label": "Excel",
+            "rdfs:comment": "A primary cutaneous neurofibroma cell line; not broadly available. See the immortalized version (icNF98.4c).",
+            "rdfs:label": "CNF98.4c",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "excel",
+            "sms:displayName": "cNF98.4c",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Powerpoint",
+            "@id": "bts:Prss56Cre;R26mT",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Microsoft Powerpoint slide format",
-            "rdfs:label": "Powerpoint",
+            "rdfs:comment": "Prss56Cre;R26mT is a transgenic non-human animal model for Neurofibromatosis type 1, wherein the Nf1 gene is specifically inactivated in BC cells and derivatives thereof.",
+            "rdfs:label": "Prss56Cre;R26mT",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "powerpoint",
+            "sms:displayName": "Prss56Cre;R26mT",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tif",
+            "@id": "bts:Nf1-OPG",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tagged Image File Format, abbreviated TIFF or TIF, is a computer file format for storing raster graphics images",
-            "rdfs:label": "Tif",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Nf1-OPG",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tif",
+            "sms:displayName": "Nf1-OPG",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Png",
+            "@id": "bts:Nf1-OPG-Arg816",
             "@type": "rdfs:Class",
-            "rdfs:comment": "PNG is a file format for image compression",
-            "rdfs:label": "Png",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Nf1-OPG-Arg816",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "png",
+            "sms:displayName": "Nf1-OPG-Arg816",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Doc",
+            "@id": "bts:Nf2-/-SchwannSC(mouse)(PMID26554010)",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Microsoft Word document format",
-            "rdfs:label": "Doc",
+            "rdfs:comment": "A Nf2-/- mouse schwann cell line; see PMID:26554010",
+            "rdfs:label": "Nf2-/-SchwannSC(mouse)(PMID26554010)",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "doc",
+            "sms:displayName": "Nf2-/- Schwann SC (mouse) (PMID26554010)",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Pdf",
+            "@id": "bts:SC4[Mouseschwannoma]",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Portable Document Format",
-            "rdfs:label": "Pdf",
+            "rdfs:comment": "Mouse schwannoma knock-out cell line (RRID:CVCL_JK03)",
+            "rdfs:label": "SC4[Mouseschwannoma]",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "pdf",
+            "sms:displayName": "SC4 [Mouse schwannoma]",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Hdf",
+            "@id": "bts:AC007-hTERT",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Hierarchical Data Format (HDF) is a set of file formats (HDF4, HDF5) designed to store and organize large amounts of data",
-            "rdfs:label": "Hdf",
+            "rdfs:comment": "Human arachnoid cell line",
+            "rdfs:label": "AC007-hTERT",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hdf",
+            "sms:displayName": "AC007-hTERT",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fasta",
+            "@id": "bts:NF2-/-AC007-hTERT",
             "@type": "rdfs:Class",
-            "rdfs:comment": "FASTA format is a text-based format for representing either nucleotide sequences or peptide sequences, in which nucleotides or amino acids are represented using single-letter codes",
-            "rdfs:label": "Fasta",
+            "rdfs:comment": "Knock-out cell line developed by CRISPR targeting NF2 exon 8 in AC007-hTERT",
+            "rdfs:label": "NF2-/-AC007-hTERT",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "fasta",
+            "sms:displayName": "NF2-/- AC007-hTERT",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fastq",
+            "@id": "bts:Ben-Men-1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "FASTQ format is a text-based format for storing both a biological sequence (usually nucleotide sequence) and its corresponding quality scores. Both the sequence letter and quality score are each encoded with a single ASCII character for brevity",
-            "rdfs:label": "Fastq",
+            "rdfs:comment": "Human meningioma cell line (RRID:CVCL_1959)",
+            "rdfs:label": "Ben-Men-1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "fastq",
+            "sms:displayName": "Ben-Men-1",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sam",
+            "@id": "bts:Humanforeskinfibroblasts",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Sequence Alignment/Map (SAM) format for alignment of nucleotide sequences (e.g. sequencing reads) to (a) reference sequence(s)",
-            "rdfs:label": "Sam",
+            "rdfs:comment": "generic human foreskin fibroblasts, often used as a control cell in toxicology experiments",
+            "rdfs:label": "Humanforeskinfibroblasts",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sam",
+            "sms:displayName": "human foreskin fibroblasts",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Vcf",
+            "@id": "bts:M3MPNST",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)",
-            "rdfs:label": "Vcf",
+            "rdfs:comment": "A patient-derived MPNST cell line",
+            "rdfs:label": "M3MPNST",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "vcf",
+            "sms:displayName": "M3 MPNST",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bcf",
+            "@id": "bts:Male",
             "@type": "rdfs:Class",
-            "rdfs:comment": "BCF, the binary version of Variant Call Format (VCF) for sequence variation (indels, polymorphisms, structural variation)",
-            "rdfs:label": "Bcf",
+            "rdfs:comment": "A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both.",
+            "rdfs:label": "Male",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Sex"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bcf",
+            "sms:displayName": "Male",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Maf",
+            "@id": "bts:Female",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Multiple Alignment Format (MAF) supporting alignments of whole genomes with rearrangements, directions, multiple pieces to the alignment, and so forth",
-            "rdfs:label": "Maf",
+            "rdfs:comment": "A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both.",
+            "rdfs:label": "Female",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Sex"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "maf",
+            "sms:displayName": "Female",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bed",
+            "@id": "bts:Unknown",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Browser Extensible Data (BED) format of sequence annotation track, typically to be displayed in a genome browser",
-            "rdfs:label": "Bed",
+            "rdfs:comment": "Not known, observed, recorded; or reported as unknown by the data contributor.",
+            "rdfs:label": "Unknown",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Sex"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bed",
+            "sms:displayName": "Unknown",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Chp",
+            "@id": "bts:Homosapiens",
             "@type": "rdfs:Class",
-            "rdfs:comment": "CHP file contains probe set analysis results generated from Affymetrix software",
-            "rdfs:label": "Chp",
+            "rdfs:comment": "Homo sapiens with taxonomy ID: 9606 and Genbank common name: human",
+            "rdfs:label": "Homosapiens",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "chp",
+            "sms:displayName": "Homo sapiens",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Cel",
+            "@id": "bts:Musmusculus",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Format of Affymetrix data file of information about (raw) expression levels of the individual probes",
-            "rdfs:label": "Cel",
+            "rdfs:comment": "Mus musculus with taxonomy ID: 10090 and Genbank common name: house mouse",
+            "rdfs:label": "Musmusculus",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "cel",
+            "sms:displayName": "Mus musculus",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sif",
+            "@id": "bts:Musmusculus(humanized)",
             "@type": "rdfs:Class",
-            "rdfs:comment": "SIF (simple interaction file) Format - a network/pathway format used for instance in cytoscape",
-            "rdfs:label": "Sif",
+            "rdfs:comment": "Mus musculus with taxonomy ID: 10090 and Genbank common name: house mouse",
+            "rdfs:label": "Musmusculus(humanized)",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sif",
+            "sms:displayName": "Mus musculus (humanized)",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tsv",
+            "@id": "bts:Rattusnorvegicus",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tabular data represented as tab-separated values in a text file",
-            "rdfs:label": "Tsv",
+            "rdfs:comment": "Rattus with taxonomy ID:10116 and Genbank common name: Norway rat",
+            "rdfs:label": "Rattusnorvegicus",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tsv",
+            "sms:displayName": "Rattus norvegicus",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Csv",
+            "@id": "bts:Drosophilamelanogaster",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tabular data represented as comma-separated values in a text file",
-            "rdfs:label": "Csv",
+            "rdfs:comment": "Drosophila melanogaster with taxonomy ID: 7227 and Genbank common name: fruit fly",
+            "rdfs:label": "Drosophilamelanogaster",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "csv",
+            "sms:displayName": "Drosophila melanogaster",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Txt",
+            "@id": "bts:Rhesusmacaque",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Textual format",
-            "rdfs:label": "Txt",
+            "rdfs:comment": "Macaca mulatta with taxonomy ID: 9544 and Genbank common name: Rhesus monkey",
+            "rdfs:label": "Rhesusmacaque",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "txt",
+            "sms:displayName": "Rhesus macaque",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Plink",
+            "@id": "bts:Pantroglodytes",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any Plink file format (MAP/PED/BED/BIM/FAM)",
-            "rdfs:label": "Plink",
+            "rdfs:comment": "Pan troglodytes with taxonomy ID: 9598 and Genbank common name: chimpanzee",
+            "rdfs:label": "Pantroglodytes",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "plink",
+            "sms:displayName": "Pan troglodytes",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bigwig",
+            "@id": "bts:Gallusgallus",
             "@type": "rdfs:Class",
-            "rdfs:comment": "bigWig format for large sequence annotation tracks that consist of a value for each sequence position",
-            "rdfs:label": "Bigwig",
+            "rdfs:comment": "The common domestic fowl, Chicken.",
+            "rdfs:label": "Gallusgallus",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bigwig",
+            "sms:displayName": "Gallus gallus",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Wiggle",
+            "@id": "bts:Susscrofa",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Wiggle format (WIG) of a sequence annotation track that consists of a value for each sequence position",
-            "rdfs:label": "Wiggle",
+            "rdfs:comment": "Sus scrofa with taxonomy ID: 9823 and Genbank common name: pig",
+            "rdfs:label": "Susscrofa",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "wiggle",
+            "sms:displayName": "Sus scrofa",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Gct",
+            "@id": "bts:Oryctolaguscuniculus",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tab-delimited text files of GenePattern that contain a column for each sample, a row for each gene, and an expression value for each gene in each sample",
-            "rdfs:label": "Gct",
+            "rdfs:comment": "Oryctolagus cuniculus with taxonomy ID: 9986 and Genbank common name: rabbit",
+            "rdfs:label": "Oryctolaguscuniculus",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "gct",
+            "sms:displayName": "Oryctolagus cuniculus",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bgzip",
+            "@id": "bts:Daniorerio",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Blocked GNU Zip format",
-            "rdfs:label": "Bgzip",
+            "rdfs:comment": "Danio rerio with taxonomy ID: 7955 and Genbank common name: zebrafish",
+            "rdfs:label": "Daniorerio",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Species"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bgzip",
+            "sms:displayName": "Danio rerio",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:ModelSystemName"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Zip",
+            "@id": "bts:Human",
             "@type": "rdfs:Class",
-            "rdfs:comment": "zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification",
-            "rdfs:label": "Zip",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Human",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TransplantationRecipientSpecies"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "zip",
+            "sms:displayName": "Human",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Seg",
+            "@id": "bts:Mouse",
             "@type": "rdfs:Class",
-            "rdfs:comment": "SEG file (segmented data; .seg or .cbs) is a tab-delimited text file that lists loci and associated numeric values",
-            "rdfs:label": "Seg",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Mouse",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TransplantationRecipientSpecies"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "seg",
+            "sms:displayName": "Mouse",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Html",
+            "@id": "bts:10xV2",
             "@type": "rdfs:Class",
-            "rdfs:comment": "HTML format",
-            "rdfs:label": "Html",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "10xV2",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "html",
+            "sms:displayName": "10x_v2",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mov",
+            "@id": "bts:FACS",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A video file format with the .mov extension",
-            "rdfs:label": "Mov",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "FACS",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mov",
+            "sms:displayName": "FACS",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Hyperlink",
+            "@id": "bts:FluidigmC1",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A reference (link) from some point in one hypertext document to another document, another place in the same document, or a website.",
-            "rdfs:label": "Hyperlink",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "FluidigmC1",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hyperlink",
+            "sms:displayName": "Fluidigm C1",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Svs",
+            "@id": "bts:Drop-seq",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A single-file pyramidal tiled TIFF, with non-standard metadata and compression.",
-            "rdfs:label": "Svs",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Drop-seq",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "svs",
+            "sms:displayName": "drop-seq",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Md",
+            "@id": "bts:InDrop",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Markdown (MD) is a lightweight markup language with plain text formatting syntax",
-            "rdfs:label": "Md",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "InDrop",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "md",
+            "sms:displayName": "inDrop",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Flagstat",
+            "@id": "bts:Mouthpipette",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Output of samtools flagstat tool",
-            "rdfs:label": "Flagstat",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Mouthpipette",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "flagstat",
+            "sms:displayName": "mouth pipette",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Gtf",
+            "@id": "bts:Enzymatic",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Gene transfer format (GTF) is a file format used to hold information about gene structure",
-            "rdfs:label": "Gtf",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Enzymatic",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "gtf",
+            "sms:displayName": "enzymatic",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Raw",
+            "@id": "bts:Mechanical",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Proprietary file format for mass spectrometry data from Thermo Scientific",
-            "rdfs:label": "Raw",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Mechanical",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:DissociationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "raw",
+            "sms:displayName": "mechanical",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Msf",
+            "@id": "bts:Viablyfrozen",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Proprietary mass-spectrometry format of Thermo Scientific's ProteomeDiscoverer software",
-            "rdfs:label": "Msf",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Viablyfrozen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "msf",
+            "sms:displayName": "Viably frozen",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Rmd",
+            "@id": "bts:Nervetissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "markdown document specific to r analyses",
-            "rdfs:label": "Rmd",
+            "rdfs:comment": "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature.",
+            "rdfs:label": "Nervetissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "rmd",
+            "sms:displayName": "nerve tissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BednarrowPeak",
+            "@id": "bts:Opticnerve",
             "@type": "rdfs:Class",
-            "rdfs:comment": "This format is used to provide called peaks of signal enrichment based on pooled, normalized (interpreted) data. It is a BED6+4 format.",
-            "rdfs:label": "BednarrowPeak",
+            "rdfs:comment": "The nerve that carries messages from the retina to the brain.",
+            "rdfs:label": "Opticnerve",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bed narrowPeak",
+            "sms:displayName": "optic nerve",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BedbroadPeak",
+            "@id": "bts:Serum",
             "@type": "rdfs:Class",
-            "rdfs:comment": "This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data. It is a BED 6+3 format.",
-            "rdfs:label": "BedbroadPeak",
+            "rdfs:comment": "Liquid derived from blood plasma that has clotting factors removed.",
+            "rdfs:label": "Serum",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bed broadPeak",
+            "sms:displayName": "serum",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:BedgappedPeak",
+            "@id": "bts:Plasma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "This format is used to provide called regions of signal enrichment based on pooled, normalized (interpreted) data where the regions may be spliced or incorporate gaps in the genomic sequence. It is a BED12+3 format.",
-            "rdfs:label": "BedgappedPeak",
+            "rdfs:comment": "Plasma is the fluid (noncellular) portion of the circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation.",
+            "rdfs:label": "Plasma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bed gappedPeak",
+            "sms:displayName": "plasma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Avi",
+            "@id": "bts:Splenocyte",
             "@type": "rdfs:Class",
-            "rdfs:comment": "AVI files can contain both audio and video data in a file container that allows synchronous audio-with-video playback.",
-            "rdfs:label": "Avi",
+            "rdfs:comment": "Any leukocyte that is part of a spleen.",
+            "rdfs:label": "Splenocyte",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "avi",
+            "sms:displayName": "splenocyte",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Pzfx",
+            "@id": "bts:Blood",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A PZFX file is a Prism project created by GraphPad Prism, a scientific application used to analyze and graph data. It contains project data including graphs and layouts, notes, and tables.",
-            "rdfs:label": "Pzfx",
+            "rdfs:comment": "A fluid that is composed of blood plasma and erythrocytes.",
+            "rdfs:label": "Blood",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "pzfx",
+            "sms:displayName": "blood",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Fig",
+            "@id": "bts:Primarytumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Line drawing saved in the Xfig format; stored as a vector image that may include lines, shapes, arcs, splines, arrows, and text objects; may also include images, colors, and patterns.",
-            "rdfs:label": "Fig",
+            "rdfs:comment": "A primary tumor is the tumor at the initial site of cancer, not where the cancer may have spread or metastasized, called the secondary tumor.",
+            "rdfs:label": "Primarytumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "fig",
+            "sms:displayName": "primary tumor",
             "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:TumorType"
+                }
+            ],
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Xml",
+            "@id": "bts:Embryonictissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "eXtensible Markup Language (XML) format.",
-            "rdfs:label": "Xml",
+            "rdfs:comment": "A portion of tissue that is part of an embryo.",
+            "rdfs:label": "Embryonictissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "xml",
+            "sms:displayName": "embryonic tissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tar",
+            "@id": "bts:Meninges",
             "@type": "rdfs:Class",
-            "rdfs:comment": "tape archive",
-            "rdfs:label": "Tar",
+            "rdfs:comment": "The three thin layers of tissue that cover and protect the brain and spinal cord.",
+            "rdfs:label": "Meninges",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tar",
+            "sms:displayName": "meninges",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Rscript",
+            "@id": "bts:Bonemarrow",
             "@type": "rdfs:Class",
-            "rdfs:comment": "R script with expected extension “.R”.",
-            "rdfs:label": "Rscript",
+            "rdfs:comment": "The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells.",
+            "rdfs:label": "Bonemarrow",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "R script",
+            "sms:displayName": "bone marrow",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Abf",
+            "@id": "bts:BuccalMucosa",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The Axon Binary File format (ABF) was created for the storage of binary experimental data.",
-            "rdfs:label": "Abf",
+            "rdfs:comment": "The mucosal membranes located on the inside of the cheek, in the buccal cavity.The inner lining of the cheeks.",
+            "rdfs:label": "BuccalMucosa",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "abf",
+            "sms:displayName": "Buccal Mucosa",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bpm",
+            "@id": "bts:DorsalRootGanglion",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A beaded pool manifest. Describe the SNP or probe content on a BeadChip or in an assay pool.",
-            "rdfs:label": "Bpm",
+            "rdfs:comment": "Ganglion with sensory function within the vertebral column.",
+            "rdfs:label": "DorsalRootGanglion",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bpm",
+            "sms:displayName": "Dorsal Root Ganglion",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Dat",
+            "@id": "bts:Cerebralcortex",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Format of Affymetrix data file of raw image data.",
-            "rdfs:label": "Dat",
+            "rdfs:comment": "The outer layer of the cerebrum composed of neurons and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other higher levels of mental function.",
+            "rdfs:label": "Cerebralcortex",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "dat",
+            "sms:displayName": "cerebral cortex",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Jpg",
+            "@id": "bts:Sciaticnerve",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Joint Picture Group file format for lossy graphics file.",
-            "rdfs:label": "Jpg",
+            "rdfs:comment": "The longest single nerve that is formed by the merging of the ventral rami of the L4, L5, and S1 in the pelvis and passes down the lower limb where it divides into the common peroneal and tibial nerves",
+            "rdfs:label": "Sciaticnerve",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "jpg",
+            "sms:displayName": "sciatic nerve",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Locs",
+            "@id": "bts:Unspecified",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Illumina iScan bead location file.",
-            "rdfs:label": "Locs",
+            "rdfs:comment": "Unspecified tissue or tissues from an organ.",
+            "rdfs:label": "Unspecified",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "locs",
+            "sms:displayName": "unspecified",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sentrixdescriptorfile",
+            "@id": "bts:Wholebrain",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A BeadScan specific file needed to perform scan setting checks for different array formats and assay type.",
-            "rdfs:label": "Sentrixdescriptorfile",
+            "rdfs:comment": "Brain tissue not limited to a specific region.",
+            "rdfs:label": "Wholebrain",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Sentrix descriptor file",
+            "sms:displayName": "whole brain",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Pythonscript",
+            "@id": "bts:BuffyCoat",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Python script with expected extension “.py”.",
-            "rdfs:label": "Pythonscript",
+            "rdfs:comment": "The middle layer of an anticoagulated blood specimen following separation by centrifugation. It contains most of the white blood cells and platelets.",
+            "rdfs:label": "BuffyCoat",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Python script",
+            "sms:displayName": "Buffy Coat",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MATLABscript",
+            "@id": "bts:Normal",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A MATLAB script file with expected extension “.m”. Note that files with a “.mat” extension contains MATLAB formatted data.",
-            "rdfs:label": "MATLABscript",
+            "rdfs:comment": "No pathological entity observable.",
+            "rdfs:label": "Normal",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "MATLAB script",
+            "sms:displayName": "normal",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MATLABdata",
+            "@id": "bts:Connectivetissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A MATLAB formatted data file with expected extension “.mat”.",
-            "rdfs:label": "MATLABdata",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Connectivetissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "MATLAB data",
+            "sms:displayName": "connective tissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sav",
+            "@id": "bts:Tumor-adjacentnormal",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The SPSS Statistics File Format is a proprietary binary format, developed and maintained as the native format for the SPSS statistical software application.",
-            "rdfs:label": "Sav",
+            "rdfs:comment": "Tissue comprised of morphologically normal tissue collected from the area immediately surrounding a tumor.",
+            "rdfs:label": "Tumor-adjacentnormal",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sav",
+            "sms:displayName": "tumor-adjacent normal",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Gzip",
+            "@id": "bts:PDXtissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "GZipped format",
-            "rdfs:label": "Gzip",
+            "rdfs:comment": "Patient derived xenograft tissue",
+            "rdfs:label": "PDXtissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "gzip",
+            "sms:displayName": "PDX tissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sdf",
+            "@id": "bts:CDXtissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "SDF is one of a family of chemical-data file formats developed by MDL Information Systems; it is intended especially for structural information.",
-            "rdfs:label": "Sdf",
+            "rdfs:comment": "Cell line derived xenograft tissue",
+            "rdfs:label": "CDXtissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sdf",
+            "sms:displayName": "CDX tissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:RData",
+            "@id": "bts:Organoid",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The RData format (usually with extension .rdata or .rda) is a format designed for use with R, a system for statistical computation and related graphics, for storing a complete R workspace or selected 'objects' from a workspace in a form that can be loaded back by R.",
-            "rdfs:label": "RData",
+            "rdfs:comment": "Organoids are three-dimensional cell culture models that self-organize into complex organ-like tissues.",
+            "rdfs:label": "Organoid",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "RData",
+            "sms:displayName": "organoid",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Hic",
+            "@id": "bts:Spheroid",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Hi-C contact matrix file",
-            "rdfs:label": "Hic",
+            "rdfs:comment": "Spheroids are 3D culture systems that can be used to model multicellular tumors; more broadly, spheroids can be defined as cell aggregates cultured on nonadherent substrates.",
+            "rdfs:label": "Spheroid",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hic",
+            "sms:displayName": "spheroid",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Ab1",
+            "@id": "bts:Microtissue",
             "@type": "rdfs:Class",
-            "rdfs:comment": "TAB1 binary format of raw DNA sequence reads (output of Applied Biosystems' sequencing analysis software). Contains an electropherogram and the DNA base sequence.",
-            "rdfs:label": "Ab1",
+            "rdfs:comment": "Microtissue usually refers to the microtissue formed by the aggregation of seed cells under the action of cell-cell or cell-extracellular matrix (ECM). Compared with traditional cell monolayer culture, cells are cultivated into a three-dimensional microstructure in a specific way. The microstructure characteristics of microtissue are similar to natural tissues and can promote cell proliferation and differentiation.",
+            "rdfs:label": "Microtissue",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "ab1",
+            "sms:displayName": "microtissue",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:7z",
+            "@id": "bts:Retina",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A compressed archive file format that supports several different data compression, encryption and pre-processing filters.",
-            "rdfs:label": "7z",
+            "rdfs:comment": "A light-sensitive membrane that lines the back wall of the eyeball. The retina is continuous with the optic nerve and this way transmits optical images to the brain. [ NCI ]",
+            "rdfs:label": "Retina",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "7z",
+            "sms:displayName": "retina",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Gff3",
+            "@id": "bts:Teratoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Generic Feature Format version 3 (GFF3) of sequence features.",
-            "rdfs:label": "Gff3",
+            "rdfs:comment": "TT",
+            "rdfs:label": "Teratoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "gff3",
+            "sms:displayName": "Teratoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Json",
+            "@id": "bts:CutaneousNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "JavaScript Object Notation format; a lightweight, text-based format to represent tree-structured data using key-value pairs.",
-            "rdfs:label": "Json",
+            "rdfs:comment": "A neurofibroma that grows along small branches of nerves in the dermis in patients with neurofibromatosis. It presents as a solid cutaneous tumor.",
+            "rdfs:label": "CutaneousNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "json",
+            "sms:displayName": "Cutaneous Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sqlite",
+            "@id": "bts:SubcutaneousNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Data format used by the SQLite database.",
-            "rdfs:label": "Sqlite",
+            "rdfs:comment": "A neurofibroma that occurs along the peripheral nerves beneath the skin.",
+            "rdfs:label": "SubcutaneousNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sqlite",
+            "sms:displayName": "Subcutaneous Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Svg",
+            "@id": "bts:PlexiformNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Scalable Vector Graphics (SVG) is an XML-based vector image format for two-dimensional graphics with support for interactivity and animation.",
-            "rdfs:label": "Svg",
+            "rdfs:comment": "An elongated and multinodular neurofibroma, formed when the tumor involves either multiple trunks of a plexus or multiple fascicles of a large nerve, such as the sciatic. Some plexiform neurofibromas resemble a bag of worms, others produce a massive ropy enlargement of the nerve.",
+            "rdfs:label": "PlexiformNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "svg",
+            "sms:displayName": "Plexiform Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sra",
+            "@id": "bts:AtypicalNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "SRA archive format (SRA) is the archive format used for input to the NCBI Sequence Read Archive.",
-            "rdfs:label": "Sra",
+            "rdfs:comment": "A neurofibroma characterized by the presence of cellular pleomorphism.",
+            "rdfs:label": "AtypicalNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sra",
+            "sms:displayName": "Atypical Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Recal",
+            "@id": "bts:MalignantPeripheralNerveSheathTumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": ".recal file from GATK VQSR",
-            "rdfs:label": "Recal",
+            "rdfs:comment": "MPNST",
+            "rdfs:label": "MalignantPeripheralNerveSheathTumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "recal",
+            "sms:displayName": "Malignant Peripheral Nerve Sheath Tumor",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tranches",
+            "@id": "bts:Glioma",
             "@type": "rdfs:Class",
-            "rdfs:comment": ".tranches file from GATK VQSR",
-            "rdfs:label": "Tranches",
+            "rdfs:comment": "A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas.",
+            "rdfs:label": "Glioma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tranches",
+            "sms:displayName": "Glioma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Mtx",
+            "@id": "bts:Low-GradeGliomaNOS",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Matrix Market Exchange Format",
-            "rdfs:label": "Mtx",
+            "rdfs:comment": "LGGNOS",
+            "rdfs:label": "Low-GradeGliomaNOS",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mtx",
+            "sms:displayName": "Low-Grade Glioma NOS",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:TagAlign",
+            "@id": "bts:PilocyticAstrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tag Alignment provides genomic mapping of short sequence tags.",
-            "rdfs:label": "TagAlign",
+            "rdfs:comment": "PAST",
+            "rdfs:label": "PilocyticAstrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tagAlign",
+            "sms:displayName": "Pilocytic Astrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Dup",
+            "@id": "bts:AtypicalPilocyticAstrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "output of the Picard MarkDuplicates tool.",
-            "rdfs:label": "Dup",
+            "rdfs:comment": "Pilocytic astrocytoma with atypical features.",
+            "rdfs:label": "AtypicalPilocyticAstrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "dup",
+            "sms:displayName": "Atypical Pilocytic Astrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DICOM",
+            "@id": "bts:PilomyxoidAstrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A comprehensive set of standards for communications between medical imaging devices, including handling, storing and transmitting information in medical imaging. It includes a file format definition and a network communication protocol.",
-            "rdfs:label": "DICOM",
+            "rdfs:comment": "PMA",
+            "rdfs:label": "PilomyxoidAstrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "DICOM",
+            "sms:displayName": "Pilomyxoid Astrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Czi",
+            "@id": "bts:DiffuseAstrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "microscopy imaging file format that saves multidimensional images such as time lapse, Z-stacks, multiposition experiments and virtual slides, combined with relevant meta information",
-            "rdfs:label": "Czi",
+            "rdfs:comment": "DA",
+            "rdfs:label": "DiffuseAstrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "czi",
+            "sms:displayName": "Diffuse Astrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MzML",
+            "@id": "bts:GlioblastomaMultiforme",
             "@type": "rdfs:Class",
-            "rdfs:comment": "mzML format for raw spectrometer output data, standardised by HUPO PSI MSS.",
-            "rdfs:label": "MzML",
+            "rdfs:comment": "GBM",
+            "rdfs:label": "GlioblastomaMultiforme",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "mzML",
+            "sms:displayName": "Glioblastoma Multiforme",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SPAR",
+            "@id": "bts:AnaplasticPilocyticAstrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Phillips MRS Header File",
-            "rdfs:label": "SPAR",
+            "rdfs:comment": "Pilocytic astrocytoma with anaplastic features exhibits a spectrum of morphologies and is associated with decreased survival when compared with typical PA.",
+            "rdfs:label": "AnaplasticPilocyticAstrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SPAR",
+            "sms:displayName": "Anaplastic Pilocytic Astrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:SDAT",
+            "@id": "bts:PleomorphicXanthoastrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Phillips MRS Data File",
-            "rdfs:label": "SDAT",
+            "rdfs:comment": "PXA",
+            "rdfs:label": "PleomorphicXanthoastrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "SDAT",
+            "sms:displayName": "Pleomorphic Xanthoastrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Nii",
+            "@id": "bts:Oligoastrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "NIfTI-1 can store image data from any modality such as PET, MRI, CT, EEG that produces regularly sampled 1-5D rasters.",
-            "rdfs:label": "Nii",
+            "rdfs:comment": "OAST",
+            "rdfs:label": "Oligoastrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "nii",
+            "sms:displayName": "Oligoastrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PAR",
+            "@id": "bts:High-GradeGliomaNOS",
             "@type": "rdfs:Class",
-            "rdfs:comment": "This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).",
-            "rdfs:label": "PAR",
+            "rdfs:comment": "HGGNOS",
+            "rdfs:label": "High-GradeGliomaNOS",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "PAR",
+            "sms:displayName": "High-Grade Glioma NOS",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:REC",
+            "@id": "bts:Unknown",
             "@type": "rdfs:Class",
-            "rdfs:comment": "This is yet another MRI image format generated by Philips scanners. It is an ASCII header (PAR) plus a binary blob (REC).",
-            "rdfs:label": "REC",
+            "rdfs:comment": "A tumor of unknown origin, or tumor type missing. ",
+            "rdfs:label": "Unknown",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "REC",
+            "sms:displayName": "Unknown",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Hdr",
+            "@id": "bts:AnaplasticAstrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "MRI Header file, as in the NIFTI-1 Analyze 7.5 format",
-            "rdfs:label": "Hdr",
+            "rdfs:comment": "AASTR",
+            "rdfs:label": "AnaplasticAstrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "hdr",
+            "sms:displayName": "Anaplastic Astrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Img",
+            "@id": "bts:Glioblastoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "MRI Data file, as in the NIFTI-1 Analyze 7.5 format",
-            "rdfs:label": "Img",
+            "rdfs:comment": "GB",
+            "rdfs:label": "Glioblastoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "img",
+            "sms:displayName": "Glioblastoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Sf",
+            "@id": "bts:Schwannoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Salmon’s main output is its quantification file. This file is a plain-text, tab-separated file with a single header line (which names all of the columns).",
-            "rdfs:label": "Sf",
+            "rdfs:comment": "SCHW",
+            "rdfs:label": "Schwannoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "sf",
+            "sms:displayName": "Schwannoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tom",
+            "@id": "bts:Meningioma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The .tom format is a specialized 3D image export format from the Vectra medical imaging systems that can optionally preserve trimmings and/or landmarks.",
-            "rdfs:label": "Tom",
+            "rdfs:comment": "MNG",
+            "rdfs:label": "Meningioma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:FileFormat"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tom",
+            "sms:displayName": "Meningioma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Genesymbol",
+            "@id": "bts:MassiveSoftTissueNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A unique gene name approved by an organism specific nomenclature committee.",
-            "rdfs:label": "Genesymbol",
+            "rdfs:comment": "Massive soft tissue neurofibroma is characterized  by local infiltration and extension to multiple nerve branches,  as well as substantial overgrowth of adjacent soft tissue and  skin, which distinguishes it from its more benign variant, plexiform neurofibroma. With striking presentation and  severe dysmorphism, massive soft tissue neurofibroma is also labeled elephantiasis neuromatosa. Although considered benign it  shares similarities with malignant peripheral nerve sheath  tumors such as local infiltration and cell mitogenesis. Massive soft tissue neurofibroma is associated with significant morbidity and mortality and almost no response to  conventional chemotherapy and radiotherapy. Surgery is eventually pursued, although bleeding may be a life-threatening  complication as massive soft tissue neurofibromas are highly  vascularized.",
+            "rdfs:label": "MassiveSoftTissueNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedDataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "gene symbol",
+            "sms:displayName": "Massive Soft Tissue Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Clinicaldata",
+            "@id": "bts:DiffuseInfiltratingNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Data obtained through patient examination or treatment.",
-            "rdfs:label": "Clinicaldata",
+            "rdfs:comment": "Diffuse infiltrating neurofibroma can present as slow-growing, soft tissue masses with overlying skin thickening. These le-sions infiltrate the dermis and the subcutaneous tissue and  characteristically spread along the connective tissues enveloping islands of normal fat. Some of these lesions develop fatty proliferation and can mimic lipomas,  angiolipomas, or angiomyolipomas on imaging and histological evaluation ",
+            "rdfs:label": "DiffuseInfiltratingNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedDataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "clinical data",
+            "sms:displayName": "Diffuse Infiltrating Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Genefunction",
+            "@id": "bts:LocalizedNeurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A term that expresses the function of a gene product.",
-            "rdfs:label": "Genefunction",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "LocalizedNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedDataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "gene function",
+            "sms:displayName": "Localized Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Chemicaldescriptor",
+            "@id": "bts:NeurofibromawithDegenerativeAtypia",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A chemical descriptor is a data item (quantity or value) about a chemical entity that conforms to a specification for how it is calculated, measured or recorded.",
-            "rdfs:label": "Chemicaldescriptor",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NeurofibromawithDegenerativeAtypia",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedDataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "chemical descriptor",
+            "sms:displayName": "Neurofibroma with Degenerative Atypia",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Individual",
+            "@id": "bts:Neurofibroma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Metadata describing properties of individuals (human or animal) represented in the study.",
-            "rdfs:label": "Individual",
+            "rdfs:comment": "NFIB",
+            "rdfs:label": "Neurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:MetadataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "individual",
+            "sms:displayName": "Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Biospecimen",
+            "@id": "bts:AnaplasticPleomorphicXanthoastrocytoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Metadata describing properties of specimens collected and/or analyzed in the study.",
-            "rdfs:label": "Biospecimen",
+            "rdfs:comment": "APXA",
+            "rdfs:label": "AnaplasticPleomorphicXanthoastrocytoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:MetadataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "biospecimen",
+            "sms:displayName": "Anaplastic Pleomorphic Xanthoastrocytoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Assay",
+            "@id": "bts:Ganglioglioma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Metadata describing properties of an assay conducted in the study.",
-            "rdfs:label": "Assay",
+            "rdfs:comment": "GNG",
+            "rdfs:label": "Ganglioglioma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:MetadataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "assay",
+            "sms:displayName": "Ganglioglioma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Datadictionary",
+            "@id": "bts:AnaplasticGanglioglioma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Metadata describing terms or variables that appear in another file.",
-            "rdfs:label": "Datadictionary",
+            "rdfs:comment": "AGNG",
+            "rdfs:label": "AnaplasticGanglioglioma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:MetadataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "data dictionary",
+            "sms:displayName": "Anaplastic Ganglioglioma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Manifest",
+            "@id": "bts:OpticPathwayGlioma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Metadata describing a list of files and the annotations terms associated with them.",
-            "rdfs:label": "Manifest",
+            "rdfs:comment": "A glioma that affects the optic nerve. This condition can be seen in association with neurofibromatosis 1. It is most commonly seen in the pediatric age group.",
+            "rdfs:label": "OpticPathwayGlioma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:MetadataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "manifest",
+            "sms:displayName": "Optic Pathway Glioma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Protocol",
+            "@id": "bts:NotApplicable",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",
-            "rdfs:label": "Protocol",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "NotApplicable",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:MetadataType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "protocol",
+            "sms:displayName": "Not Applicable",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GRCh38",
+            "@id": "bts:ColorectalAdenocarcinoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Genome Reference Consortium Human Build 38",
-            "rdfs:label": "GRCh38",
+            "rdfs:comment": "(COADREAD) The most common type of colorectal carcinoma. It is chararactized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa.",
+            "rdfs:label": "ColorectalAdenocarcinoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ReferenceSet"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GRCh38",
+            "sms:displayName": "Colorectal Adenocarcinoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GRCh37",
+            "@id": "bts:ColorectalCarcinoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Genome Reference Consortium Human Build 37",
-            "rdfs:label": "GRCh37",
+            "rdfs:comment": "A malignant epithelial neoplasm that arrises from the colon or rectum and invates through the muscularis mucosa into the submucosa. 95 percent of colorectal carcinoma are colorectal adenocarcinoma -- use this more specific term if it applies.",
+            "rdfs:label": "ColorectalCarcinoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ReferenceSet"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "GRCh37",
+            "sms:displayName": "Colorectal Carcinoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MMUL1.0",
+            "@id": "bts:RecurrentMPNST",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Ensembl preliminary assembly Macaca mulatta",
-            "rdfs:label": "MMUL1.0",
+            "rdfs:comment": "The reemergence of malignant peripheral nerve sheath tumor after a period of remission.",
+            "rdfs:label": "RecurrentMPNST",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ReferenceSet"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "MMUL1.0",
+            "sms:displayName": "Recurrent MPNST",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:HRC",
+            "@id": "bts:JuvenileMyelomonocyticLeukemia",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Human haplotype reference panel",
-            "rdfs:label": "HRC",
+            "rdfs:comment": "(JMML) A myelodysplastic/myeloproliferative neoplasm of childhood that is characterized by proliferation principally of the granulocytic and monocytic lineages",
+            "rdfs:label": "JuvenileMyelomonocyticLeukemia",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ReferenceSet"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "HRC",
+            "sms:displayName": "Juvenile Myelomonocytic Leukemia",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ExperimentalData",
+            "@id": "bts:Sarcoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any file derived from or pertaining to a scientific experiment. experimentalData annotations should be applied, possibly disease-related",
-            "rdfs:label": "ExperimentalData",
+            "rdfs:comment": "(SARCNOS) An usually aggressive malignant neoplasm of the soft tissue or bone...Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.",
+            "rdfs:label": "Sarcoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "experimentalData",
+            "sms:displayName": "Sarcoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Result",
+            "@id": "bts:Fibromatosis",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any file that reports data results. Examples include figures, presentations, analysis, etc.",
-            "rdfs:label": "Result",
+            "rdfs:comment": "A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern.",
+            "rdfs:label": "Fibromatosis",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "result",
+            "sms:displayName": "Fibromatosis",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Tool",
+            "@id": "bts:Fibrosarcoma",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Any file or link that represents a tool, model, or algorithm; the tool annotations could be applied",
-            "rdfs:label": "Tool",
+            "rdfs:comment": "(FIBS) A malignant mesenchymal fibroblastic neoplasm affecting the soft tissue and bone.",
+            "rdfs:label": "Fibrosarcoma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "tool",
+            "sms:displayName": "Fibrosarcoma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Workflowreport",
+            "@id": "bts:NecroticNeoplasm",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Workflow-generated reports of analysis of primary data, usually created programmatically at completion of workflow step.",
-            "rdfs:label": "Workflowreport",
+            "rdfs:comment": "A neoplasm characterized by focal or diffuse tumor cell necrosis.",
+            "rdfs:label": "NecroticNeoplasm",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "workflow report",
+            "sms:displayName": "Necrotic Neoplasm",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Report",
+            "@id": "bts:HemorrhagicNeoplasm",
             "@type": "rdfs:Class",
-            "rdfs:comment": "a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).",
-            "rdfs:label": "Report",
+            "rdfs:comment": "A neoplasm with hemorrhagic findings.",
+            "rdfs:label": "HemorrhagicNeoplasm",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "report",
+            "sms:displayName": "Hemorrhagic Neoplasm",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Metadata",
+            "@id": "bts:NF1-AssociatedTumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Data about data; information that describes another set of data.",
-            "rdfs:label": "Metadata",
+            "rdfs:comment": "Unspecified NF1-associated tumor; use a more specific tumor classification if available.",
+            "rdfs:label": "NF1-AssociatedTumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "metadata",
+            "sms:displayName": "NF1-Associated Tumor",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Protocol",
+            "@id": "bts:NF2-AssociatedTumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",
-            "rdfs:label": "Protocol",
+            "rdfs:comment": "Unspecified NF2-associated tumor; use a more specific tumor classification if available.",
+            "rdfs:label": "NF2-AssociatedTumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ResourceType"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "protocol",
+            "sms:displayName": "NF2-Associated Tumor",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CuratedDataType",
+            "@id": "bts:ANNUBP",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The type of information being curated.",
-            "rdfs:label": "CuratedDataType",
+            "rdfs:comment": "Atypical neurofibromatous neoplasms of uncertain biologic potential is a provisional classification for lesions displaying at least two features: atypia, loss of neurofibroma architecture, high cellularity, and/or mitotic activity >1/50 but <3/10 high power fields. They can be inconsistently diagnosed as atypical neurofibroma or low-grade MPNST. See https://pubmed.ncbi.nlm.nih.gov/28551330/.",
+            "rdfs:label": "ANNUBP",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedData"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Referencesequence"
-                },
-                {
-                    "@id": "bts:Genesymbol"
-                },
-                {
-                    "@id": "bts:Clinicaldata"
-                },
-                {
-                    "@id": "bts:Genefunction"
-                },
-                {
-                    "@id": "bts:Chemicaldescriptor"
-                }
-            ],
-            "sms:displayName": "curatedDataType",
-            "sms:required": "sms:true",
+            "sms:displayName": "ANNUBP",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ReferenceSet",
+            "@id": "bts:Tumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A set of references (e.g., canonical assembled contigs) which defines a common coordinate space for comparing reference-aligned experimental data.",
-            "rdfs:label": "ReferenceSet",
+            "rdfs:comment": "General term for tumor sample – use when it is unknown when a more specific clinical classification is unknown, e.g. whether it is primary or secondary.",
+            "rdfs:label": "Tumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedData"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:GRCh38"
-                },
-                {
-                    "@id": "bts:GRCh37"
-                },
-                {
-                    "@id": "bts:MMUL1.0"
-                },
-                {
-                    "@id": "bts:HRC"
+                    "@id": "bts:Tissue"
                 }
             ],
-            "sms:displayName": "referenceSet",
-            "sms:required": "sms:true",
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "tumor",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Referencesequence",
+            "@id": "bts:Metastatictumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Syntactic sequences that has a role as reference of an annotation.",
-            "rdfs:label": "Referencesequence",
+            "rdfs:comment": "For neoplasms, a non-infiltrating and non-metastasizing neoplastic process that is characterized by the absence of morphologic features associated with malignancy (e.g., severe atypia, nuclear pleomorphism, tumor cell necrosis, and abnormal mitoses).",
+            "rdfs:label": "Metastatictumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:CuratedDataType"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "reference sequence",
+            "sms:displayName": "metastatic tumor",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DataSubtype",
+            "@id": "bts:Metastatic/recurrenttumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Further qualification of dataType, which may be used to indicate the state of processing of the data, aggregation of the data, or presence of metadata.",
-            "rdfs:label": "DataSubtype",
+            "rdfs:comment": "A tumor with metastatic/recurrent characteristic.",
+            "rdfs:label": "Metastatic/recurrenttumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Normalized"
-                },
-                {
-                    "@id": "bts:DataMatrix"
-                },
-                {
-                    "@id": "bts:Raw"
-                },
-                {
-                    "@id": "bts:Processed"
-                },
-                {
-                    "@id": "bts:Metadata"
-                },
-                {
-                    "@id": "bts:Representative"
-                }
-            ],
-            "sms:displayName": "dataSubtype",
-            "sms:required": "sms:true",
+            "sms:displayName": "metastatic/recurrent tumor",
+            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MetadataType",
+            "@id": "bts:Recurrenttumor",
             "@type": "rdfs:Class",
-            "rdfs:comment": "For files of dataSubtype: metadata, a description of the type of metadata in the file.",
-            "rdfs:label": "MetadataType",
+            "rdfs:comment": "A tumor described with recurrent characteristic.",
+            "rdfs:label": "Recurrenttumor",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:Tissue"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Individual"
-                },
-                {
-                    "@id": "bts:Biospecimen"
-                },
-                {
-                    "@id": "bts:Assay"
-                },
-                {
-                    "@id": "bts:Datadictionary"
-                },
-                {
-                    "@id": "bts:Manifest"
-                },
-                {
-                    "@id": "bts:Protocol"
-                }
-            ],
-            "sms:displayName": "metadataType",
+            "sms:displayName": "recurrent tumor",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:DataType",
+            "@id": "bts:TumorType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "A type of experimental, clinical, or other data. This typically refers to a high-level data type that can be related to an assay type. For example, a file of dataType `genomicVariants` might have an assay value of `whole genome sequencing`.",
-            "rdfs:label": "DataType",
+            "rdfs:comment": "The type of tumor that the biospecimen used to generate the data were collected from.",
+            "rdfs:label": "TumorType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:Cancer"
                 }
             ],
             "schema:isPartOf": {
@@ -15502,271 +15911,181 @@
             },
             "schema:rangeIncludes": [
                 {
-                    "@id": "bts:Volume"
+                    "@id": "bts:Teratoma"
                 },
                 {
-                    "@id": "bts:Weight"
+                    "@id": "bts:CutaneousNeurofibroma"
                 },
                 {
-                    "@id": "bts:PharmacokineticStudy"
+                    "@id": "bts:SubcutaneousNeurofibroma"
                 },
                 {
-                    "@id": "bts:GenomicVariants"
+                    "@id": "bts:PlexiformNeurofibroma"
                 },
                 {
-                    "@id": "bts:Behaviorprocess"
+                    "@id": "bts:AtypicalNeurofibroma"
                 },
                 {
-                    "@id": "bts:Metabolomics"
+                    "@id": "bts:MalignantPeripheralNerveSheathTumor"
                 },
                 {
-                    "@id": "bts:Image"
+                    "@id": "bts:Glioma"
                 },
                 {
-                    "@id": "bts:GeneExpression"
+                    "@id": "bts:Low-GradeGliomaNOS"
                 },
                 {
-                    "@id": "bts:IsoformExpression"
+                    "@id": "bts:PilocyticAstrocytoma"
                 },
                 {
-                    "@id": "bts:Proteomics"
+                    "@id": "bts:AtypicalPilocyticAstrocytoma"
                 },
                 {
-                    "@id": "bts:Kinomics"
+                    "@id": "bts:PilomyxoidAstrocytoma"
                 },
                 {
-                    "@id": "bts:DrugScreen"
+                    "@id": "bts:DiffuseAstrocytoma"
                 },
                 {
-                    "@id": "bts:DrugCombinationScreen"
+                    "@id": "bts:GlioblastomaMultiforme"
                 },
                 {
-                    "@id": "bts:CellularPhysiology"
+                    "@id": "bts:AnaplasticPilocyticAstrocytoma"
                 },
                 {
-                    "@id": "bts:ChromatinActivity"
+                    "@id": "bts:PleomorphicXanthoastrocytoma"
                 },
                 {
-                    "@id": "bts:SurveyData"
+                    "@id": "bts:Oligoastrocytoma"
                 },
                 {
-                    "@id": "bts:Network"
+                    "@id": "bts:High-GradeGliomaNOS"
                 },
                 {
-                    "@id": "bts:Clinical"
+                    "@id": "bts:Unknown"
                 },
                 {
-                    "@id": "bts:Immunoassay"
+                    "@id": "bts:AnaplasticAstrocytoma"
                 },
                 {
-                    "@id": "bts:Electrophysiology"
+                    "@id": "bts:Glioblastoma"
                 },
                 {
-                    "@id": "bts:Rawcounts"
+                    "@id": "bts:Schwannoma"
                 },
                 {
-                    "@id": "bts:Maskimage"
+                    "@id": "bts:Meningioma"
                 },
                 {
-                    "@id": "bts:AlignedReads"
+                    "@id": "bts:MassiveSoftNeurofibroma"
                 },
                 {
-                    "@id": "bts:SomaticVariants"
+                    "@id": "bts:DiffuseInfiltratingNeurofibroma"
                 },
                 {
-                    "@id": "bts:AnnotatedSomaticVariants"
+                    "@id": "bts:LocalizedNeurofibroma"
                 },
                 {
-                    "@id": "bts:StructuralVariants"
+                    "@id": "bts:NeurofibromawithDegenerativeAtypia"
                 },
                 {
-                    "@id": "bts:GermlineVariants"
+                    "@id": "bts:Neurofibroma"
                 },
                 {
-                    "@id": "bts:AnnotatedGermlineVariants"
-                }
-            ],
-            "sms:displayName": "dataType",
-            "sms:required": "sms:true",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:DataSubtype"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ExpressionUnit",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Measure used for transcript expression quantification",
-            "rdfs:label": "ExpressionUnit",
-            "rdfs:subClassOf": [
-                {
-                    "@id": "bts:ExperimentalData"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:TPM"
+                    "@id": "bts:AnaplasticPleomorphicXanthoastrocytoma"
                 },
                 {
-                    "@id": "bts:RPKM"
+                    "@id": "bts:Ganglioglioma"
                 },
                 {
-                    "@id": "bts:FPKM"
+                    "@id": "bts:AnaplasticGanglioglioma"
                 },
                 {
-                    "@id": "bts:Counts"
+                    "@id": "bts:OpticPathwayGlioma"
                 },
                 {
-                    "@id": "bts:Other"
-                }
-            ],
-            "sms:displayName": "expressionUnit",
-            "sms:required": "sms:true",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:FailedQC",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Whether the sample or data failed QC checks (Yes; No)",
-            "rdfs:label": "FailedQC",
-            "rdfs:subClassOf": [
-                {
-                    "@id": "bts:ExperimentalData"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Yes"
+                    "@id": "bts:NotApplicable"
                 },
                 {
-                    "@id": "bts:No"
-                }
-            ],
-            "sms:displayName": "failedQC",
-            "sms:required": "sms:true",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Filename",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "The name of the file.",
-            "rdfs:label": "Filename",
-            "rdfs:subClassOf": [
-                {
-                    "@id": "bts:NF"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Filename",
-            "sms:required": "sms:true",
-            "sms:requiresDependency": [
-                {
-                    "@id": "bts:EntityId"
+                    "@id": "bts:ColorectalCarcinoma"
                 },
                 {
-                    "@id": "bts:FileFormat"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ProgrammingLanguage",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A computer programming language",
-            "rdfs:label": "ProgrammingLanguage",
-            "rdfs:subClassOf": [
-                {
-                    "@id": "schema:Thing"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
-                {
-                    "@id": "bts:Python"
+                    "@id": "bts:RecurrentMPNST"
                 },
                 {
-                    "@id": "bts:R"
+                    "@id": "bts:JuvenileMyelomonocyticLeukemia"
                 },
                 {
-                    "@id": "bts:MATLAB"
+                    "@id": "bts:Sarcoma"
                 },
                 {
-                    "@id": "bts:Java"
+                    "@id": "bts:Fibromatosis"
                 },
                 {
-                    "@id": "bts:C"
+                    "@id": "bts:Fibrosarcoma"
                 },
                 {
-                    "@id": "bts:C++"
+                    "@id": "bts:NecroticNeoplasm"
                 },
                 {
-                    "@id": "bts:C#"
+                    "@id": "bts:HemorrhagicNeoplasm"
                 },
                 {
-                    "@id": "bts:Javascript"
+                    "@id": "bts:NF1-AssociatedTumor"
                 },
                 {
-                    "@id": "bts:Bash"
+                    "@id": "bts:NF2-AssociatedTumor"
                 }
             ],
-            "sms:displayName": "programmingLanguage",
+            "sms:displayName": "tumorType",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:RuntimePlatform",
+            "@id": "bts:Diagnosis",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Runtime platform or script interpreter dependencies (e.g. Java v1, Python 2.3).",
-            "rdfs:label": "RuntimePlatform",
+            "rdfs:comment": "A diagnosis is the result of a medical investigation to identify a disorder from its signs and symptoms.",
+            "rdfs:label": "Diagnosis",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "runtimePlatform",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Documentation",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "URL to any documentation describing the resource and its use.",
-            "rdfs:label": "Documentation",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Neurofibromatosistype1"
+                },
+                {
+                    "@id": "bts:Neurofibromatosistype2"
+                },
+                {
+                    "@id": "bts:Schwannomatosis"
+                },
+                {
+                    "@id": "bts:Unknown"
+                },
+                {
+                    "@id": "bts:NotApplicable"
+                },
+                {
+                    "@id": "bts:SporadicSchwannoma"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "documentation",
+            "sms:displayName": "diagnosis",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ResourceType",
+            "@id": "bts:BodyPart",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The type of resource being stored and annotated",
-            "rdfs:label": "ResourceType",
+            "rdfs:comment": "Sample location referring to a named area of the body, inclusive of gross anatomical structures and organ parts. ",
+            "rdfs:label": "BodyPart",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SageCommunity"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
@@ -15774,655 +16093,731 @@
             },
             "schema:rangeIncludes": [
                 {
-                    "@id": "bts:ExperimentalData"
+                    "@id": "bts:Head"
                 },
                 {
-                    "@id": "bts:CuratedData"
+                    "@id": "bts:Neck"
                 },
                 {
-                    "@id": "bts:Result"
+                    "@id": "bts:Scalp"
                 },
                 {
-                    "@id": "bts:Tool"
+                    "@id": "bts:Leg"
                 },
                 {
-                    "@id": "bts:Report"
+                    "@id": "bts:Pelvis"
                 },
                 {
-                    "@id": "bts:Metadata"
+                    "@id": "bts:Mesentery"
                 },
                 {
-                    "@id": "bts:Protocol"
+                    "@id": "bts:Axilla"
                 },
                 {
-                    "@id": "bts:Workflowreport"
-                }
-            ],
-            "sms:displayName": "resourceType",
-            "sms:required": "sms:true",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:FileFormat",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Defined format of the data file, typically corresponding to extension, but sometimes indicating more general group of files produced by the same tool or software",
-            "rdfs:label": "FileFormat",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Acetabulum"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
+                    "@id": "bts:Forearm"
+                },
                 {
-                    "@id": "bts:Bashscript"
+                    "@id": "bts:Muscle"
                 },
                 {
-                    "@id": "bts:Bedgraph"
+                    "@id": "bts:Finger"
                 },
                 {
-                    "@id": "bts:Ai"
+                    "@id": "bts:Thoracicspine"
                 },
                 {
-                    "@id": "bts:Idx"
+                    "@id": "bts:Groin"
                 },
                 {
-                    "@id": "bts:Idat"
+                    "@id": "bts:Back"
                 },
                 {
-                    "@id": "bts:Bam"
+                    "@id": "bts:Iliacspine"
                 },
                 {
-                    "@id": "bts:Bai"
+                    "@id": "bts:Spine"
                 },
                 {
-                    "@id": "bts:Excel"
+                    "@id": "bts:Shoulder"
                 },
                 {
-                    "@id": "bts:Powerpoint"
+                    "@id": "bts:Scapula"
                 },
                 {
-                    "@id": "bts:Tif"
+                    "@id": "bts:Lymphnode"
                 },
                 {
-                    "@id": "bts:Png"
+                    "@id": "bts:Kidney"
                 },
                 {
-                    "@id": "bts:Doc"
+                    "@id": "bts:Skin"
                 },
                 {
-                    "@id": "bts:Pdf"
+                    "@id": "bts:Mammarygland"
                 },
                 {
-                    "@id": "bts:Hdf"
+                    "@id": "bts:Nerves"
                 },
                 {
-                    "@id": "bts:Fasta"
+                    "@id": "bts:Brain"
                 },
                 {
-                    "@id": "bts:Fastq"
+                    "@id": "bts:Blood"
                 },
                 {
-                    "@id": "bts:Sam"
+                    "@id": "bts:Breast"
                 },
                 {
-                    "@id": "bts:Vcf"
+                    "@id": "bts:Colon"
                 },
                 {
-                    "@id": "bts:Bcf"
+                    "@id": "bts:Lung"
                 },
                 {
-                    "@id": "bts:Maf"
+                    "@id": "bts:Liver"
                 },
                 {
-                    "@id": "bts:Bed"
+                    "@id": "bts:Prostate"
                 },
                 {
-                    "@id": "bts:Chp"
+                    "@id": "bts:Pancreas"
                 },
                 {
-                    "@id": "bts:Cel"
+                    "@id": "bts:Ovary"
                 },
                 {
-                    "@id": "bts:Sif"
+                    "@id": "bts:Spleen"
                 },
                 {
-                    "@id": "bts:Tsv"
+                    "@id": "bts:Bonemarrow"
                 },
                 {
-                    "@id": "bts:Csv"
+                    "@id": "bts:BursaOfFabricius"
                 },
                 {
-                    "@id": "bts:Txt"
+                    "@id": "bts:Nose"
+                }
+            ],
+            "sms:displayName": "bodyPart",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Organ",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues. An organ is part of an anatomic system or a body region.",
+            "rdfs:label": "Organ",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:ExperimentalData"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Lymphnode"
                 },
                 {
-                    "@id": "bts:Plink"
+                    "@id": "bts:Kidney"
                 },
                 {
-                    "@id": "bts:Bigwig"
+                    "@id": "bts:Skin"
                 },
                 {
-                    "@id": "bts:Wiggle"
+                    "@id": "bts:Mammarygland"
                 },
                 {
-                    "@id": "bts:Gct"
+                    "@id": "bts:Nerves"
                 },
                 {
-                    "@id": "bts:Bgzip"
+                    "@id": "bts:Brain"
                 },
                 {
-                    "@id": "bts:Zip"
+                    "@id": "bts:Blood"
                 },
                 {
-                    "@id": "bts:Seg"
+                    "@id": "bts:Breast"
                 },
                 {
-                    "@id": "bts:Html"
+                    "@id": "bts:Colon"
                 },
                 {
-                    "@id": "bts:Mov"
+                    "@id": "bts:Lung"
                 },
                 {
-                    "@id": "bts:Hyperlink"
+                    "@id": "bts:Liver"
                 },
                 {
-                    "@id": "bts:Svs"
+                    "@id": "bts:Prostate"
                 },
                 {
-                    "@id": "bts:Md"
+                    "@id": "bts:Pancreas"
+                },
+                {
+                    "@id": "bts:Ovary"
+                },
+                {
+                    "@id": "bts:Spleen"
+                },
+                {
+                    "@id": "bts:Bonemarrow"
+                },
+                {
+                    "@id": "bts:BursaOfFabricius"
+                },
+                {
+                    "@id": "bts:Nose"
+                },
+                {
+                    "@id": "bts:Eye"
+                }
+            ],
+            "sms:displayName": "organ",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IndividualIdSource",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Database or repository to which individual ID maps",
+            "rdfs:label": "IndividualIdSource",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:ExperimentalData"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "individualIdSource",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Tissue",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A tissue is a mereologically maximal collection of cells that together perform physiological function.",
+            "rdfs:label": "Tissue",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:ExperimentalData"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Nervetissue"
                 },
                 {
-                    "@id": "bts:Flagstat"
+                    "@id": "bts:Opticnerve"
                 },
                 {
-                    "@id": "bts:Gtf"
+                    "@id": "bts:Serum"
                 },
                 {
-                    "@id": "bts:Raw"
+                    "@id": "bts:Plasma"
                 },
                 {
-                    "@id": "bts:Msf"
+                    "@id": "bts:Splenocyte"
                 },
                 {
-                    "@id": "bts:Rmd"
+                    "@id": "bts:Blood"
                 },
                 {
-                    "@id": "bts:BednarrowPeak"
+                    "@id": "bts:Primarytumor"
                 },
                 {
-                    "@id": "bts:BedbroadPeak"
+                    "@id": "bts:Embryonictissue"
                 },
                 {
-                    "@id": "bts:BedgappedPeak"
+                    "@id": "bts:Meninges"
                 },
                 {
-                    "@id": "bts:Avi"
+                    "@id": "bts:Bonemarrow"
                 },
                 {
-                    "@id": "bts:Pzfx"
+                    "@id": "bts:BuccalMucosa"
                 },
                 {
-                    "@id": "bts:Fig"
+                    "@id": "bts:DorsalRootGanglion"
                 },
                 {
-                    "@id": "bts:Xml"
+                    "@id": "bts:Unspecified"
                 },
                 {
-                    "@id": "bts:Tar"
+                    "@id": "bts:Wholebrain"
                 },
                 {
-                    "@id": "bts:Rscript"
+                    "@id": "bts:BuffyCoat"
                 },
                 {
-                    "@id": "bts:Abf"
+                    "@id": "bts:Cerebralcortex"
                 },
                 {
-                    "@id": "bts:Bpm"
+                    "@id": "bts:Sciaticnerve"
                 },
                 {
-                    "@id": "bts:Dat"
+                    "@id": "bts:Connectivetissue"
                 },
                 {
-                    "@id": "bts:Jpg"
+                    "@id": "bts:Tumor-adjacentnormal"
                 },
                 {
-                    "@id": "bts:Locs"
+                    "@id": "bts:PDXtissue"
                 },
                 {
-                    "@id": "bts:Sentrixdescriptorfile"
+                    "@id": "bts:CDXtissue"
                 },
                 {
-                    "@id": "bts:Pythonscript"
+                    "@id": "bts:Metastatic/recurrenttumor"
                 },
                 {
-                    "@id": "bts:Sav"
+                    "@id": "bts:Recurrenttumor"
                 },
                 {
-                    "@id": "bts:Gzip"
+                    "@id": "bts:Metastatictumor"
                 },
                 {
-                    "@id": "bts:Sdf"
+                    "@id": "bts:Organoid"
                 },
                 {
-                    "@id": "bts:RData"
+                    "@id": "bts:Spheroid"
                 },
                 {
-                    "@id": "bts:Hic"
+                    "@id": "bts:Microtissue"
                 },
                 {
-                    "@id": "bts:Ab1"
-                },
+                    "@id": "bts:Retina"
+                }
+            ],
+            "sms:displayName": "tissue",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IsCellLine",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Whether or not sample source is a cell line (Yes; No)",
+            "rdfs:label": "IsCellLine",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:7z"
-                },
+                    "@id": "bts:ExperimentalData"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:Gff3"
+                    "@id": "bts:Yes"
                 },
                 {
-                    "@id": "bts:Json"
-                },
+                    "@id": "bts:No"
+                }
+            ],
+            "sms:displayName": "isCellLine",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:IsPrimaryCell",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Whether or not cellType is primary (Yes; No)",
+            "rdfs:label": "IsPrimaryCell",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Sqlite"
-                },
+                    "@id": "bts:ExperimentalData"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:Svg"
+                    "@id": "bts:Yes"
                 },
                 {
-                    "@id": "bts:Sra"
-                },
+                    "@id": "bts:No"
+                }
+            ],
+            "sms:displayName": "isPrimaryCell",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:CellType",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "A cell type is a distinct morphological or functional form of cell.",
+            "rdfs:label": "CellType",
+            "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Recal"
-                },
+                    "@id": "bts:ExperimentalData"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:Tranches"
+                    "@id": "bts:Schwanncellprecursor"
                 },
                 {
-                    "@id": "bts:Mtx"
+                    "@id": "bts:B-lymphocytes"
                 },
                 {
-                    "@id": "bts:TagAlign"
+                    "@id": "bts:Embryonicstemcells"
                 },
                 {
-                    "@id": "bts:Dup"
+                    "@id": "bts:IPSC"
                 },
                 {
-                    "@id": "bts:DICOM"
+                    "@id": "bts:IPSC-derivedtelencephalicorganoids"
                 },
                 {
-                    "@id": "bts:Czi"
+                    "@id": "bts:GABAergicneurons"
                 },
                 {
-                    "@id": "bts:MzML"
+                    "@id": "bts:Monocytes"
                 },
                 {
-                    "@id": "bts:SPAR"
+                    "@id": "bts:Microglia"
                 },
                 {
-                    "@id": "bts:SDAT"
+                    "@id": "bts:Macrophages"
                 },
                 {
-                    "@id": "bts:Nii"
+                    "@id": "bts:Astrocytes"
                 },
                 {
-                    "@id": "bts:PAR"
+                    "@id": "bts:SH-SY5Y"
                 },
                 {
-                    "@id": "bts:REC"
+                    "@id": "bts:GLUtamatergicneurons"
                 },
                 {
-                    "@id": "bts:Hdr"
+                    "@id": "bts:NeuN+"
                 },
                 {
-                    "@id": "bts:Img"
+                    "@id": "bts:NeuN-"
                 },
                 {
-                    "@id": "bts:Sf"
+                    "@id": "bts:Epithelial"
                 },
                 {
-                    "@id": "bts:MATLABscript"
+                    "@id": "bts:Epithelial-like"
                 },
                 {
-                    "@id": "bts:MATLABdata"
+                    "@id": "bts:Fibroblast"
                 },
                 {
-                    "@id": "bts:Tom"
-                }
-            ],
-            "sms:displayName": "fileFormat",
-            "sms:required": "sms:true",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ProgressReportNumber",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Indicates milestone the  data is associated with. Currently only required for projects funded by NTAP, GFF, and NFRI. For GFF studies, this is the ‘progress report’ timeline. Example: if submitting data for the 6-month milestone report for NTAP, progressReportNumber=1.  Also if submitting data associated with first milestone, progressReportNumber =1",
-            "rdfs:label": "ProgressReportNumber",
-            "rdfs:subClassOf": [
-                {
-                    "@id": "bts:Template"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
+                    "@id": "bts:Round"
+                },
                 {
-                    "@id": "bts:1"
+                    "@id": "bts:Lymphoblast"
                 },
                 {
-                    "@id": "bts:2"
+                    "@id": "bts:CD8+T-Cells"
                 },
                 {
-                    "@id": "bts:3"
+                    "@id": "bts:Arachnoid"
                 },
                 {
-                    "@id": "bts:4"
+                    "@id": "bts:Meningioma"
                 },
                 {
-                    "@id": "bts:5"
+                    "@id": "bts:Schwannoma"
                 },
                 {
-                    "@id": "bts:6"
+                    "@id": "bts:Oligodendrocyte"
                 },
                 {
-                    "@id": "bts:7"
+                    "@id": "bts:Schwann"
                 },
                 {
-                    "@id": "bts:8"
+                    "@id": "bts:IPSC-derivedneuron"
                 },
                 {
-                    "@id": "bts:9"
+                    "@id": "bts:IPSC-derivedglia"
                 },
                 {
-                    "@id": "bts:10"
+                    "@id": "bts:IPSC-derivedastrocytes"
                 },
                 {
-                    "@id": "bts:NotApplicable"
-                }
-            ],
-            "sms:displayName": "progressReportNumber",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Comments",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Brief free-text comments that may also be important to understanding the resource.",
-            "rdfs:label": "Comments",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Monocyte-derivedmicroglia"
+                },
                 {
-                    "@id": "bts:ExperimentalData"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "comments",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ResourceId",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A UUID for a Resource from the NF Research Tools Database",
-            "rdfs:label": "ResourceId",
-            "rdfs:subClassOf": [
+                    "@id": "bts:IPSC-derivedneuronalprogenitorcell"
+                },
                 {
-                    "@id": "bts:DccProperty"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "Resource_id",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Initiative",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to a funding initiative. This annotation is usually handled by the DCC or funder, not the researcher. ",
-            "rdfs:label": "Initiative",
-            "rdfs:subClassOf": [
+                    "@id": "bts:CD138+"
+                },
                 {
-                    "@id": "bts:DccProperty"
+                    "@id": "bts:CNON"
+                },
+                {
+                    "@id": "bts:Teratoma"
+                },
+                {
+                    "@id": "bts:CulturedMullerglia"
+                },
+                {
+                    "@id": "bts:DRG/nerverootneurospherecell"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "initiative",
+            "sms:displayName": "cellType",
             "sms:required": "sms:false",
-            "sms:validationRules": []
+            "sms:validationRules": [
+                "list like"
+            ]
         },
         {
-            "@id": "bts:FundingAgency",
+            "@id": "bts:IsMultiIndividual",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to the funding organization for the generated resource. This annotation is handled by the DCC.",
-            "rdfs:label": "FundingAgency",
+            "rdfs:comment": "Whether or not a file has data for multiple individuals (Yes; No)",
+            "rdfs:label": "IsMultiIndividual",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:DccProperty"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "fundingAgency",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:CreatedOn",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to when the resource was created on the platform.",
-            "rdfs:label": "CreatedOn",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:Yes"
+                },
+                {
+                    "@id": "bts:No"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "createdOn",
-            "sms:required": "sms:false",
+            "sms:displayName": "isMultiIndividual",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CreatedBy",
+            "@id": "bts:IsMultiSpecimen",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to the user who created the resource on the platform.",
-            "rdfs:label": "CreatedBy",
+            "rdfs:comment": "Whether or not a file has data for multiple specimens (Yes; No)",
+            "rdfs:label": "IsMultiSpecimen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "createdBy",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ModifiedBy",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to a user who last modified the resource on the platform.",
-            "rdfs:label": "ModifiedBy",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:Yes"
+                },
+                {
+                    "@id": "bts:No"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "modifiedBy",
-            "sms:required": "sms:false",
+            "sms:displayName": "isMultiSpecimen",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Id",
+            "@id": "bts:Sex",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The entity id for the resource automatically assigned by the platform.",
-            "rdfs:label": "Id",
+            "rdfs:comment": "Phenotypic expression of chromosomal makeup that defines a study subject as male, female, or other.",
+            "rdfs:label": "Sex",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "id",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Etag",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Synapse employs an Optimistic Concurrency Control (OCC) scheme to handle concurrent updates. The E-Tag changes every time an entity is updated it is used to detect when a client's current representation of an entity is out-of-date.",
-            "rdfs:label": "Etag",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:Male"
+                },
+                {
+                    "@id": "bts:Female"
+                },
+                {
+                    "@id": "bts:Unknown"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "etag",
+            "sms:displayName": "sex",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ParentId",
+            "@id": "bts:Species",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The id of the parent resource, i.e. the parent folder on the platform. ",
-            "rdfs:label": "ParentId",
+            "rdfs:comment": "The name of a species (typically a taxonomic group) of organism.",
+            "rdfs:label": "Species",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "parentId",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:BenefactorId",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "The id of the resource from which access control is inherited.",
-            "rdfs:label": "BenefactorId",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:Homosapiens"
+                },
+                {
+                    "@id": "bts:Musmusculus"
+                },
+                {
+                    "@id": "bts:Musmusculus(humanized)"
+                },
+                {
+                    "@id": "bts:Rattusnorvegicus"
+                },
+                {
+                    "@id": "bts:Drosophilamelanogaster"
+                },
+                {
+                    "@id": "bts:Rhesusmacaque"
+                },
+                {
+                    "@id": "bts:Pantroglodytes"
+                },
+                {
+                    "@id": "bts:Gallusgallus"
+                },
+                {
+                    "@id": "bts:Susscrofa"
+                },
+                {
+                    "@id": "bts:Oryctolaguscuniculus"
+                },
+                {
+                    "@id": "bts:Daniorerio"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "benefactorId",
-            "sms:required": "sms:false",
+            "sms:displayName": "species",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:CurrentVersion",
+            "@id": "bts:IndividualID",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(Versionable entities only) The current version number of the resource.",
-            "rdfs:label": "CurrentVersion",
+            "rdfs:comment": "A unique identifier (non-PII) that represents the individual from which the data came. This could be a patient or animal ID.",
+            "rdfs:label": "IndividualID",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "currentVersion",
+            "sms:displayName": "individualID",
             "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:DataFileHandleId",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "(Files only) Refers to the id of the file.",
-            "rdfs:label": "DataFileHandleId",
-            "rdfs:subClassOf": [
+            "sms:requiresDependency": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:Sex"
+                },
+                {
+                    "@id": "bts:Age"
+                },
+                {
+                    "@id": "bts:AgeUnit"
+                },
+                {
+                    "@id": "bts:Species"
+                },
+                {
+                    "@id": "bts:Diagnosis"
+                },
+                {
+                    "@id": "bts:Nf1Genotype"
+                },
+                {
+                    "@id": "bts:Nf2Genotype"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "dataFileHandleId",
-            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ContentSize",
+            "@id": "bts:ParentSpecimenID",
             "@type": "rdfs:Class",
-            "rdfs:comment": "(Files only) File size calculated by the platform.",
-            "rdfs:label": "ContentSize",
+            "rdfs:comment": "A unique identifier (non-PII) that represents the parent specimen (sample) from which the data came from, e.g. the single parent tumor. The parentSpecimenIDcan be the same as specimenID when there is no subsectioning.",
+            "rdfs:label": "ParentSpecimenID",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "schema:Thing"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "contentSize",
+            "sms:displayName": "parentSpecimenID",
             "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Type",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to the type of the resource on the platform, e.g. “file”.",
-            "rdfs:label": "Type",
-            "rdfs:subClassOf": [
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:SpecimenID"
+                },
+                {
+                    "@id": "bts:AliquotID"
+                },
+                {
+                    "@id": "bts:Organ"
+                },
+                {
+                    "@id": "bts:Tissue"
+                },
+                {
+                    "@id": "bts:IsCellLine"
+                },
+                {
+                    "@id": "bts:IsPrimaryCell"
+                },
+                {
+                    "@id": "bts:CellType"
+                },
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:TumorType"
+                },
+                {
+                    "@id": "bts:SpecimenPreparationMethod"
+                },
+                {
+                    "@id": "bts:ModelSystemName"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "type",
-            "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ConcreteType",
+            "@id": "bts:SpecimenID",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Refers to the class model the data platform uses for representing the resource. This is a low-level field set by the platform and is not a user annotation.",
-            "rdfs:label": "ConcreteType",
+            "rdfs:comment": "A unique identifier (non-PII) that represents the subspecimen (subsample) from which the data came, e.g. an ID that distinguishes between different parts of the same parent tumor specimen. This can be the A A unique identifier (non-PII) that represents the",
+            "rdfs:label": "SpecimenID",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SynapseProperty"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "concreteType",
+            "sms:displayName": "specimenID",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Author",
+            "@id": "bts:SpecimenIDSource",
             "@type": "rdfs:Class",
-            "rdfs:comment": "The author of the resource; preferably use an ORCID ID, GitHub profile link, etc., if available and a text name if not.",
-            "rdfs:label": "Author",
+            "rdfs:comment": "Optional annotation describing where the specimen ID source derived from, e.g. the biobank providing samples or a providing lab.",
+            "rdfs:label": "SpecimenIDSource",
             "rdfs:subClassOf": [
                 {
                     "@id": "schema:Thing"
@@ -16431,15 +16826,15 @@
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "author",
+            "sms:displayName": "specimenIDSource",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:License",
+            "@id": "bts:AliquotID",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Link to a license or name of license applicable for the resource.",
-            "rdfs:label": "License",
+            "rdfs:comment": "A unique identifier (non-PII) that represents the aliquots used for e.g. replicate runs. This is linked to the specimenID. ",
+            "rdfs:label": "AliquotID",
             "rdfs:subClassOf": [
                 {
                     "@id": "schema:Thing"
@@ -16448,476 +16843,340 @@
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "license",
+            "sms:displayName": "aliquotID",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Allograft",
+            "@id": "bts:ModelSystemName",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Tissues, cells, or organs transplanted between genetically different individuals of the same species",
-            "rdfs:label": "Allograft",
+            "rdfs:comment": "A group of presumed common ancestry with clear-cut physiological but usually not morphological distinctions such as an animal model or cell line. EXAMPLE(S):  HEK293T (cell line), Minnesota5 (swine strain), DXL (poultry strain), RB51 (vaccine strain of Brucella abortus)",
+            "rdfs:label": "ModelSystemName",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TransplantationType"
+                    "@id": "bts:Neuro"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "allograft",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Xenograft",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Tissues, cells or organs transplanted between animals of different species",
-            "rdfs:label": "Xenograft",
-            "rdfs:subClassOf": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:TransplantationType"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "xenograft",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:C57BL/6J"
+                },
                 {
-                    "@id": "bts:TransplantationRecipientSpecies"
+                    "@id": "bts:NODscidgamma"
                 },
                 {
-                    "@id": "bts:TransplantationRecipientTissue"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Autograft",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Transplant comprised of an individual's own tissue, transferred from one part of the body to another.",
-            "rdfs:label": "Autograft",
-            "rdfs:subClassOf": [
+                    "@id": "bts:B6;129S2-Trp53tm1TyjNf1tm1Tyj/J"
+                },
                 {
-                    "@id": "bts:TransplantationType"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "autograft",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:B6;129-Trp53tm1TyjNf1tm1TyjSuz12Gt(Betageo)1Khe/KcichJ"
+                },
                 {
-                    "@id": "bts:TransplantationRecipientSpecies"
+                    "@id": "bts:B6.129S2-Nf1tm1Tyj/J"
                 },
                 {
-                    "@id": "bts:TransplantationRecipientTissue"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Isograft",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Tissues, cells or organs transplanted between genetically identical individuals",
-            "rdfs:label": "Isograft",
-            "rdfs:subClassOf": [
+                    "@id": "bts:B6.129S1-Nf1tm1Cbr/J"
+                },
                 {
-                    "@id": "bts:TransplantationType"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "isograft",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Seconds",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Seconds",
-            "rdfs:subClassOf": [
+                    "@id": "bts:B6.129(Cg)-Nf1tm1Par/J"
+                },
+                {
+                    "@id": "bts:HiPSC-SCP"
+                },
+                {
+                    "@id": "bts:HiPSC"
+                },
+                {
+                    "@id": "bts:JHU2-103-CL"
+                },
+                {
+                    "@id": "bts:JHU2-002-CL"
+                },
+                {
+                    "@id": "bts:JHU2-079-CL"
+                },
+                {
+                    "@id": "bts:JHU2-103-PDX"
+                },
+                {
+                    "@id": "bts:JHU2-002-PDX"
+                },
+                {
+                    "@id": "bts:JHU2-079-PDX"
+                },
+                {
+                    "@id": "bts:Humanforeskinfibroblasts"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF05.5"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF05.5(Mixedclones)"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipn06.2A"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF95.11bC/T"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF95.6"
+                },
+                {
+                    "@id": "bts:HTERTSCipn02.8"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipnNF95.11c"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF95.11bC"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipnNF09.4"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF04.4"
+                },
+                {
+                    "@id": "bts:HTERTNF1sipnNF95.12B"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF00.6"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipNF03.3"
+                },
+                {
+                    "@id": "bts:HTERTNF1ipn02.32λ"
+                },
+                {
+                    "@id": "bts:HTERTSCipn02.8"
+                },
+                {
+                    "@id": "bts:SZ-NF1"
+                },
+                {
+                    "@id": "bts:SZ-NF2"
+                },
+                {
+                    "@id": "bts:SZ-NF4"
+                },
+                {
+                    "@id": "bts:NF1"
+                },
+                {
+                    "@id": "bts:Lis42NF11N"
+                },
+                {
+                    "@id": "bts:Lis47NF12N"
+                },
+                {
+                    "@id": "bts:ST88-14"
+                },
+                {
+                    "@id": "bts:SNF96.2"
+                },
+                {
+                    "@id": "bts:SNF02.2"
+                },
+                {
+                    "@id": "bts:SNF94.3"
+                },
+                {
+                    "@id": "bts:GM11602"
+                },
+                {
+                    "@id": "bts:GM11601"
+                },
+                {
+                    "@id": "bts:KCL024"
+                },
+                {
+                    "@id": "bts:KCL025"
+                },
+                {
+                    "@id": "bts:5PNFTdiPSsvPM6"
+                },
+                {
+                    "@id": "bts:5PNFTdiPSsvMM4"
+                },
+                {
+                    "@id": "bts:7PNFSiPSrvPM12"
+                },
+                {
+                    "@id": "bts:6PNFSiPSrvPM2"
+                },
+                {
+                    "@id": "bts:3PNFSiPSsvMM11"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "seconds",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Minutes",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Minutes",
-            "rdfs:subClassOf": [
+                    "@id": "bts:3PNFFiPSsvPM2"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "minutes",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Hours",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Hours",
-            "rdfs:subClassOf": [
+                    "@id": "bts:NCC-MPNST5-C1"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "hours",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Days",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Days",
-            "rdfs:subClassOf": [
+                    "@id": "bts:NCC-MPNST3-C1"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "days",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Weeks",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Weeks",
-            "rdfs:subClassOf": [
+                    "@id": "bts:NCC-MPNST4-C1"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "weeks",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Months",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "Months",
-            "rdfs:subClassOf": [
+                    "@id": "bts:NCC-MPNST3-X2-C1"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "months",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:Quarters",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Time point unit referring to quarters in a year.",
-            "rdfs:label": "Quarters",
-            "rdfs:subClassOf": [
+                    "@id": "bts:NCC-MPNST2-C1"
+                },
                 {
-                    "@id": "schema:Thing"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "quarters",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:TransplantationType",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Type of transplantation involved in the experiment, derived from MESH",
-            "rdfs:label": "TransplantationType",
-            "rdfs:subClassOf": [
+                    "@id": "bts:STS-26T"
+                },
                 {
-                    "@id": "bts:Cancer"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
+                    "@id": "bts:YST-1"
+                },
                 {
-                    "@id": "bts:Allograft"
+                    "@id": "bts:90-8"
                 },
                 {
-                    "@id": "bts:Xenograft"
+                    "@id": "bts:S520"
                 },
                 {
-                    "@id": "bts:Autograft"
+                    "@id": "bts:S462"
                 },
                 {
-                    "@id": "bts:Isograft"
-                }
-            ],
-            "sms:displayName": "transplantationType",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:S462.TY"
+                },
                 {
-                    "@id": "bts:TransplantationRecipientSpecies"
+                    "@id": "bts:Sc93.1"
                 },
                 {
-                    "@id": "bts:TransplantationRecipientTissue"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:TransplantationRecipientSpecies",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Species into which donor tissue was grown",
-            "rdfs:label": "TransplantationRecipientSpecies",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Fb93.1"
+                },
                 {
-                    "@id": "bts:Cancer"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
+                    "@id": "bts:JH-2-002-CL"
+                },
                 {
-                    "@id": "bts:Human"
+                    "@id": "bts:JH-2-079-CL"
                 },
                 {
-                    "@id": "bts:Mouse"
-                }
-            ],
-            "sms:displayName": "transplantationRecipientSpecies",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:TimePointUnit",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "For timed experiments this represents the unit of time measured",
-            "rdfs:label": "TimePointUnit",
-            "rdfs:subClassOf": [
+                    "@id": "bts:JH-2-103-CL"
+                },
                 {
-                    "@id": "bts:Cancer"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "schema:rangeIncludes": [
+                    "@id": "bts:IcNF00.10a"
+                },
                 {
-                    "@id": "bts:Seconds"
+                    "@id": "bts:CNF00.10a"
                 },
                 {
-                    "@id": "bts:Minutes"
+                    "@id": "bts:IcNF97.2a"
                 },
                 {
-                    "@id": "bts:Hours"
+                    "@id": "bts:CNF97.2a"
                 },
                 {
-                    "@id": "bts:Days"
+                    "@id": "bts:IcNF97.2b"
                 },
                 {
-                    "@id": "bts:Weeks"
+                    "@id": "bts:CNF97.2b"
                 },
                 {
-                    "@id": "bts:Months"
+                    "@id": "bts:IcNF98.4d"
                 },
                 {
-                    "@id": "bts:Quarters"
-                }
-            ],
-            "sms:displayName": "timePointUnit",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ExperimentalCondition",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A free-text description of the experimental condition (e.g. 5 mM doxorubicin).",
-            "rdfs:label": "ExperimentalCondition",
-            "rdfs:subClassOf": [
+                    "@id": "bts:CNF98.4d"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "experimentalCondition",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ExperimentalTimepoint",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "The numeric value indicating the time elapsed from the beginning of the experiment at which the specimen was collected. Use in tandem with timePointUnit",
-            "rdfs:label": "ExperimentalTimepoint",
-            "rdfs:subClassOf": [
+                    "@id": "bts:I28cNF"
+                },
+                {
+                    "@id": "bts:28cNF"
+                },
+                {
+                    "@id": "bts:IcNF04.9a"
+                },
+                {
+                    "@id": "bts:CNF04.9a"
+                },
+                {
+                    "@id": "bts:IcNF98.4c"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "experimentalTimepoint",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:CNF98.4c"
+                },
                 {
-                    "@id": "bts:TimePointUnit"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:TransplantationRecipientTissue",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Tissue into which a xenograph sample is transplanted",
-            "rdfs:label": "TransplantationRecipientTissue",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Nf2-/-SchwannSC(mouse)(PMID26554010)"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "transplantationRecipientTissue",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:ExperimentId",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "When applicable, an optional identifier that can be used to distinguish or group the experiments that generated the data; also can be used to denote internal batch reference if needed.",
-            "rdfs:label": "ExperimentId",
-            "rdfs:subClassOf": [
+                    "@id": "bts:SC4[Mouseschwannoma]"
+                },
                 {
-                    "@id": "bts:SageCommunity"
+                    "@id": "bts:AC007-hTERT"
+                },
+                {
+                    "@id": "bts:NF2-/-AC007-hTERT"
+                },
+                {
+                    "@id": "bts:Ben-Men-1"
+                },
+                {
+                    "@id": "bts:M3MPNST"
+                },
+                {
+                    "@id": "bts:NRG"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "experimentId",
+            "sms:displayName": "modelSystemName",
             "sms:required": "sms:false",
-            "sms:validationRules": []
+            "sms:validationRules": [
+                "list like"
+            ]
         },
         {
-            "@id": "bts:CompoundName",
+            "@id": "bts:Nf2Genotype",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Common name for a compound, e.g. “Selumetinib” (https://pubchem.ncbi.nlm.nih.gov/compound/10127622)",
-            "rdfs:label": "CompoundName",
+            "rdfs:comment": "Genotype of NF2 gene in the biospecimen from which the data were derived, if known",
+            "rdfs:label": "Nf2Genotype",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SageCommunity"
+                    "@id": "bts:Neurofibromatosis"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "compoundName",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+            "schema:rangeIncludes": [
                 {
-                    "@id": "bts:InChIKey"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:CompoundDose",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A dose quantity for the treatment compound. To be used with compoundDoseUnit.",
-            "rdfs:label": "CompoundDose",
-            "rdfs:subClassOf": [
+                    "@id": "bts:-/-"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "compoundDose",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:+/-"
+                },
                 {
-                    "@id": "bts:CompoundDoseUnit"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:CompoundDoseUnit",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A unit associated with the value(s) in compoundDose.",
-            "rdfs:label": "CompoundDoseUnit",
-            "rdfs:subClassOf": [
+                    "@id": "bts:+/+"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "compoundDoseUnit",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:InChIKey",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "A unique hash key for a compound, e.g. for “Selumetinib”, the key is CYOHGALHFOKKQC-UHFFFAOYSA-N (https://pubchem.ncbi.nlm.nih.gov/compound/10127622#section=InChI-Key). This is a more reliable identifier than the compound name and should be used if available.",
-            "rdfs:label": "InChIKey",
-            "rdfs:subClassOf": [
+                    "@id": "bts:+/?"
+                },
                 {
-                    "@id": "bts:SageCommunity"
+                    "@id": "bts:-/?"
+                },
+                {
+                    "@id": "bts:Unknown"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "InChIKey",
+            "sms:displayName": "nf2Genotype",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GenePerturbationType",
+            "@id": "bts:Nf1Genotype",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Specific way in which a single gene was perturbed in a sample",
-            "rdfs:label": "GenePerturbationType",
+            "rdfs:comment": "Genotype of NF1 gene in the biospecimen from which the data were derived, if known",
+            "rdfs:label": "Nf1Genotype",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Cancer"
+                    "@id": "bts:Neurofibromatosis"
                 }
             ],
             "schema:isPartOf": {
@@ -16925,33 +17184,36 @@
             },
             "schema:rangeIncludes": [
                 {
-                    "@id": "bts:Overexpression"
+                    "@id": "bts:-/-"
                 },
                 {
-                    "@id": "bts:Knockdown"
+                    "@id": "bts:+/-"
                 },
                 {
-                    "@id": "bts:Knockout"
+                    "@id": "bts:+/+"
                 },
                 {
-                    "@id": "bts:Non-targetingcontrol"
+                    "@id": "bts:+/?"
                 },
                 {
-                    "@id": "bts:NotApplicable"
+                    "@id": "bts:-/?"
+                },
+                {
+                    "@id": "bts:Unknown"
                 }
             ],
-            "sms:displayName": "genePerturbationType",
+            "sms:displayName": "nf1Genotype",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GenePerturbationTechnology",
+            "@id": "bts:SpecimenPreparationMethod",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Technology used to perform gene perturbation",
-            "rdfs:label": "GenePerturbationTechnology",
+            "rdfs:comment": "Term that represents preservation of the sample before usage in, e.g. sequencing",
+            "rdfs:label": "SpecimenPreparationMethod",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Cancer"
+                    "@id": "bts:Ngs"
                 }
             ],
             "schema:isPartOf": {
@@ -16959,83 +17221,42 @@
             },
             "schema:rangeIncludes": [
                 {
-                    "@id": "bts:RNAi"
+                    "@id": "bts:Freshcollected"
                 },
                 {
-                    "@id": "bts:CRISPR"
+                    "@id": "bts:Flashfrozen"
                 },
                 {
-                    "@id": "bts:CRERecombinase"
-                }
-            ],
-            "sms:displayName": "genePerturbationTechnology",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:GenePerturbed",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "The HUGO gene symbol for the gene that is perturbed.",
-            "rdfs:label": "GenePerturbed",
-            "rdfs:subClassOf": [
+                    "@id": "bts:FFPE"
+                },
                 {
-                    "@id": "bts:SageCommunity"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "genePerturbed",
-            "sms:required": "sms:false",
-            "sms:requiresDependency": [
+                    "@id": "bts:Cryopreserved"
+                },
                 {
-                    "@id": "bts:GenePerturbationType"
+                    "@id": "bts:OCT"
                 },
                 {
-                    "@id": "bts:GenePerturbationTechnology"
-                }
-            ],
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:JAX",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "The Jackson Laboratory",
-            "rdfs:label": "JAX",
-            "rdfs:subClassOf": [
+                    "@id": "bts:RNAlater"
+                },
                 {
-                    "@id": "bts:IndividualIdSource"
-                }
-            ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "JAX",
-            "sms:required": "sms:false",
-            "sms:validationRules": []
-        },
-        {
-            "@id": "bts:SageCommunity",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "TBD",
-            "rdfs:label": "SageCommunity",
-            "rdfs:subClassOf": [
+                    "@id": "bts:Formalin-fixed"
+                },
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Ethanol"
+                },
+                {
+                    "@id": "bts:Viablyfrozen"
                 }
             ],
-            "schema:isPartOf": {
-                "@id": "http://schema.biothings.io"
-            },
-            "sms:displayName": "sageCommunity",
+            "sms:displayName": "specimenPreparationMethod",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Workflow",
+            "@id": "bts:Age",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Name and version of the workflow used to generate/analyze the data",
-            "rdfs:label": "Workflow",
+            "rdfs:comment": "A numeric value representing age of the individual. Use with ageUnit.",
+            "rdfs:label": "Age",
             "rdfs:subClassOf": [
                 {
                     "@id": "schema:Thing"
@@ -17044,20 +17265,22 @@
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "workflow",
+            "sms:displayName": "age",
             "sms:required": "sms:false",
             "sms:requiresDependency": [
                 {
-                    "@id": "bts:WorkflowLink"
+                    "@id": "bts:AgeUnit"
                 }
             ],
-            "sms:validationRules": []
+            "sms:validationRules": [
+                "num"
+            ]
         },
         {
-            "@id": "bts:WorkflowLink",
+            "@id": "bts:AgeUnit",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Workflow URL reference",
-            "rdfs:label": "WorkflowLink",
+            "rdfs:comment": "A time unit that can be used with a given age value, e.g. years.",
+            "rdfs:label": "AgeUnit",
             "rdfs:subClassOf": [
                 {
                     "@id": "schema:Thing"
@@ -17066,15 +17289,26 @@
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "workflowLink",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Days"
+                },
+                {
+                    "@id": "bts:Months"
+                },
+                {
+                    "@id": "bts:Years"
+                }
+            ],
+            "sms:displayName": "ageUnit",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:GenomicReference",
+            "@id": "bts:BioSampleUsed",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Version of genome reference used for alignment in processing workflow",
-            "rdfs:label": "GenomicReference",
+            "rdfs:comment": "The biosample used.",
+            "rdfs:label": "BioSampleUsed",
             "rdfs:subClassOf": [
                 {
                     "@id": "schema:Thing"
@@ -17083,160 +17317,196 @@
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "genomicReference",
+            "sms:displayName": "bioSampleUsed",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AverageInsertSize",
+            "@id": "bts:IsXenograft",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Average insert size as reported by samtools",
-            "rdfs:label": "AverageInsertSize",
+            "rdfs:comment": "Whether or not sample source is a xenograft (Yes; No)",
+            "rdfs:label": "IsXenograft",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:ExperimentalData"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "averageInsertSize",
-            "sms:required": "sms:false",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Yes"
+                },
+                {
+                    "@id": "bts:No"
+                }
+            ],
+            "sms:displayName": "isXenograft",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AverageReadLength",
+            "@id": "bts:SourceName",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Average read length collected from samtools",
-            "rdfs:label": "AverageReadLength",
+            "rdfs:comment": " identifies the source from where the sample is derived. If the sample assayed is a nanoparticle sample or some chemical substance not derived from a biological material, then the corresponding source name should refer to the starting sample that was modified by a protocol for the assay.",
+            "rdfs:label": "SourceName",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:SourceName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "averageReadLength",
-            "sms:required": "sms:false",
+            "sms:displayName": "sourceName",
+            "sms:required": "sms:true",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:AverageBaseQuality",
+            "@id": "bts:SampleType",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Average base quality collected from samtools",
-            "rdfs:label": "AverageBaseQuality",
+            "rdfs:comment": "Type of sample",
+            "rdfs:label": "SampleType",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:SampleType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "averageBaseQuality",
+            "sms:displayName": "sampleType",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:PairsOnDifferentChr",
-            "@type": "rdfs:Class",
-            "rdfs:comment": "Pairs on different chromosomes collected from samtools",
-            "rdfs:label": "PairsOnDifferentChr",
-            "rdfs:subClassOf": [
-                {
-                    "@id": "schema:Thing"
-                }
-            ],
+            "@id": "bts:materialType",
+            "@type": "rdf:Property",
+            "rdfs:comment": "Type of material in the characterization",
+            "rdfs:label": "materialType",
+            "schema:domainIncludes": {
+                "@id": "bts:DNA"
+            },
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "pairsOnDifferentChr",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Nanoparticles"
+                },
+                {
+                    "@id": "bts:Polymericnanoparticles"
+                },
+                {
+                    "@id": "bts:Smallmolecule"
+                },
+                {
+                    "@id": "bts:DNA"
+                }
+            ],
+            "sms:displayName": "materialType",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ReadsDuplicatedPercent",
+            "@id": "bts:PH",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Percent of duplicated reads collected from samtools",
-            "rdfs:label": "ReadsDuplicatedPercent",
+            "rdfs:comment": "Numeric value for pH sample parameter",
+            "rdfs:label": "PH",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Parameter"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "readsDuplicatedPercent",
+            "sms:displayName": "pH",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ReadsMappedPercent",
+            "@id": "bts:ConcentrationMaterial",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Percent of mapped reads collected from samtools",
-            "rdfs:label": "ReadsMappedPercent",
+            "rdfs:comment": "Numeric value for concentration of the material",
+            "rdfs:label": "ConcentrationMaterial",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Parameter"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "readsMappedPercent",
+            "sms:displayName": "concentrationMaterial",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MeanCoverage",
+            "@id": "bts:ConcentrationMaterialUnit",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Mean coverage for whole genome sequencing, or mean target coverage for whole exome and targeted sequencing, collected from Picard Tools",
-            "rdfs:label": "MeanCoverage",
+            "rdfs:comment": "Unit used for the material concentration, e.g. mg/mL",
+            "rdfs:label": "ConcentrationMaterialUnit",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Parameter"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "meanCoverage",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Mg/mL"
+                },
+                {
+                    "@id": "bts:MM"
+                }
+            ],
+            "sms:displayName": "concentrationMaterialUnit",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ProportionCoverage10x",
+            "@id": "bts:ConcentrationNaCl",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 10X or greater coverage from Picard Tools",
-            "rdfs:label": "ProportionCoverage10x",
+            "rdfs:comment": "Numeric value for NaCl concentration",
+            "rdfs:label": "ConcentrationNaCl",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Parameter"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "proportionCoverage10x",
+            "sms:displayName": "concentrationNaCl",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:ProportionCoverage30x",
+            "@id": "bts:ConcentrationNaClUnit",
             "@type": "rdfs:Class",
-            "rdfs:comment": "Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 30X or greater coverage from Picard Tools",
-            "rdfs:label": "ProportionCoverage30x",
+            "rdfs:comment": "Unit used for the NaCl concentration, e.g. mM",
+            "rdfs:label": "ConcentrationNaClUnit",
             "rdfs:subClassOf": [
                 {
-                    "@id": "schema:Thing"
+                    "@id": "bts:Parameter"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "proportionCoverage30x",
+            "schema:rangeIncludes": [
+                {
+                    "@id": "bts:Mg/mL"
+                },
+                {
+                    "@id": "bts:MM"
+                }
+            ],
+            "sms:displayName": "concentrationNaClUnit",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
@@ -19100,6 +19370,58 @@
             ],
             "sms:validationRules": []
         },
+        {
+            "@id": "bts:DynamicLightScatteringTemplate",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "Template for dynamic light scattering data adapted from ISA-TAB-Nano specs (https://wiki.nci.nih.gov/display/icr/isa-tab-nano)",
+            "rdfs:label": "DynamicLightScatteringTemplate",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:Template"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "DynamicLightScatteringTemplate",
+            "sms:required": "sms:false",
+            "sms:requiresDependency": [
+                {
+                    "@id": "bts:Component"
+                },
+                {
+                    "@id": "bts:Filename"
+                },
+                {
+                    "@id": "bts:ResourceType"
+                },
+                {
+                    "@id": "bts:DataType"
+                },
+                {
+                    "@id": "bts:Assay"
+                },
+                {
+                    "@id": "bts:materialType"
+                },
+                {
+                    "@id": "bts:PH"
+                },
+                {
+                    "@id": "bts:ConcentrationMaterial"
+                },
+                {
+                    "@id": "bts:ConcentrationMaterialUnit"
+                },
+                {
+                    "@id": "bts:ConcentrationNaCl"
+                },
+                {
+                    "@id": "bts:ConcentrationNaClUnit"
+                }
+            ],
+            "sms:validationRules": []
+        },
         {
             "@id": "bts:Nuclei",
             "@type": "rdfs:Class",
@@ -19220,631 +19542,699 @@
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MassiveSoftNeurofibroma",
+            "@id": "bts:TPM",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "MassiveSoftNeurofibroma",
+            "rdfs:label": "TPM",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:TumorType"
+                    "@id": "bts:ExpressionUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Massive Soft \nNeurofibroma",
+            "sms:displayName": "TPM",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:5PNFTdiPSsvPM6",
+            "@id": "bts:RPKM",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "5PNFTdiPSsvPM6",
+            "rdfs:label": "RPKM",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExpressionUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "5PNF_TdiPSsv_PM_6",
+            "sms:displayName": "RPKM",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:5PNFTdiPSsvMM4",
+            "@id": "bts:FPKM",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "5PNFTdiPSsvMM4",
+            "rdfs:label": "FPKM",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ModelSystemName"
+                    "@id": "bts:ExpressionUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "5PNF_TdiPSsv_MM_4",
+            "sms:displayName": "FPKM",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Counts",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Counts",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:ExpressionUnit"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Counts",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Other",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Other",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:ExpressionUnit"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Other",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:EntityId",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "EntityId",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:Filename"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "entityId",
+            "sms:required": "sms:false",
+            "sms:validationRules": []
+        },
+        {
+            "@id": "bts:Python",
+            "@type": "rdfs:Class",
+            "rdfs:comment": "TBD",
+            "rdfs:label": "Python",
+            "rdfs:subClassOf": [
+                {
+                    "@id": "bts:ProgrammingLanguage"
+                }
+            ],
+            "schema:isPartOf": {
+                "@id": "http://schema.biothings.io"
+            },
+            "sms:displayName": "Python",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:+/?",
+            "@id": "bts:R",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "+/?",
+            "rdfs:label": "R",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "+/?",
+            "sms:displayName": "R",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:-/?",
+            "@id": "bts:MATLAB",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "-/?",
+            "rdfs:label": "MATLAB",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Nf2Genotype"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "-/?",
+            "sms:displayName": "MATLAB",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Freshcollected",
+            "@id": "bts:Java",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Freshcollected",
+            "rdfs:label": "Java",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Fresh collected",
+            "sms:displayName": "Java",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Flashfrozen",
+            "@id": "bts:C",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Flashfrozen",
+            "rdfs:label": "C",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Flash frozen",
+            "sms:displayName": "C",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:FFPE",
+            "@id": "bts:C++",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "FFPE",
+            "rdfs:label": "C++",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "FFPE",
+            "sms:displayName": "C++",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Cryopreserved",
+            "@id": "bts:C#",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Cryopreserved",
+            "rdfs:label": "C#",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Cryopreserved",
+            "sms:displayName": "C#",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:OCT",
+            "@id": "bts:Javascript",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "OCT",
+            "rdfs:label": "Javascript",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "OCT",
+            "sms:displayName": "Javascript",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:RNAlater",
+            "@id": "bts:Bash",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "RNAlater",
+            "rdfs:label": "Bash",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgrammingLanguage"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "RNAlater",
+            "sms:displayName": "bash",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Formalin-fixed",
+            "@id": "bts:3",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Formalin-fixed",
+            "rdfs:label": "3",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "formalin-fixed",
+            "sms:displayName": "3",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Ethanol",
+            "@id": "bts:4",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Ethanol",
+            "rdfs:label": "4",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:SpecimenPreparationMethod"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "ethanol",
+            "sms:displayName": "4",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Years",
+            "@id": "bts:5",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Years",
+            "rdfs:label": "5",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:AgeUnit"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "years",
+            "sms:displayName": "5",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:TPM",
+            "@id": "bts:6",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "TPM",
+            "rdfs:label": "6",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExpressionUnit"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "TPM",
+            "sms:displayName": "6",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:RPKM",
+            "@id": "bts:7",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "RPKM",
+            "rdfs:label": "7",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExpressionUnit"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "RPKM",
+            "sms:displayName": "7",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:FPKM",
+            "@id": "bts:8",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "FPKM",
+            "rdfs:label": "8",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExpressionUnit"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "FPKM",
+            "sms:displayName": "8",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Counts",
+            "@id": "bts:9",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Counts",
+            "rdfs:label": "9",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExpressionUnit"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Counts",
+            "sms:displayName": "9",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Other",
+            "@id": "bts:10",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Other",
+            "rdfs:label": "10",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ExpressionUnit"
+                    "@id": "bts:ProgressReportNumber"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Other",
+            "sms:displayName": "10",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:EntityId",
+            "@id": "bts:MassiveSoftNeurofibroma",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "EntityId",
+            "rdfs:label": "MassiveSoftNeurofibroma",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:Filename"
+                    "@id": "bts:TumorType"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "entityId",
+            "sms:displayName": "Massive Soft Neurofibroma",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Python",
+            "@id": "bts:5PNFTdiPSsvPM6",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Python",
+            "rdfs:label": "5PNFTdiPSsvPM6",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Python",
+            "sms:displayName": "5PNF_TdiPSsv_PM_6",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:R",
+            "@id": "bts:5PNFTdiPSsvMM4",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "R",
+            "rdfs:label": "5PNFTdiPSsvMM4",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:ModelSystemName"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "R",
+            "sms:displayName": "5PNF_TdiPSsv_MM_4",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:MATLAB",
+            "@id": "bts:+/?",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "MATLAB",
+            "rdfs:label": "+/?",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:Nf2Genotype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "MATLAB",
+            "sms:displayName": "+/?",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Java",
+            "@id": "bts:-/?",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Java",
+            "rdfs:label": "-/?",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:Nf2Genotype"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Java",
+            "sms:displayName": "-/?",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:C",
+            "@id": "bts:Freshcollected",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "C",
+            "rdfs:label": "Freshcollected",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "C",
+            "sms:displayName": "Fresh collected",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:C++",
+            "@id": "bts:Flashfrozen",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "C++",
+            "rdfs:label": "Flashfrozen",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "C++",
+            "sms:displayName": "Flash frozen",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:C#",
+            "@id": "bts:FFPE",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "C#",
+            "rdfs:label": "FFPE",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "C#",
+            "sms:displayName": "FFPE",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Javascript",
+            "@id": "bts:Cryopreserved",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Javascript",
+            "rdfs:label": "Cryopreserved",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "Javascript",
+            "sms:displayName": "Cryopreserved",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:Bash",
+            "@id": "bts:OCT",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "Bash",
+            "rdfs:label": "OCT",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgrammingLanguage"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "bash",
+            "sms:displayName": "OCT",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:3",
+            "@id": "bts:RNAlater",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "3",
+            "rdfs:label": "RNAlater",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "3",
+            "sms:displayName": "RNAlater",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:4",
+            "@id": "bts:Formalin-fixed",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "4",
+            "rdfs:label": "Formalin-fixed",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "4",
+            "sms:displayName": "formalin-fixed",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:5",
+            "@id": "bts:Ethanol",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "5",
+            "rdfs:label": "Ethanol",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:SpecimenPreparationMethod"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "5",
+            "sms:displayName": "ethanol",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:6",
+            "@id": "bts:Years",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "6",
+            "rdfs:label": "Years",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:AgeUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "6",
+            "sms:displayName": "years",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:7",
+            "@id": "bts:Nanoparticles",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "7",
+            "rdfs:label": "Nanoparticles",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:DNA"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "7",
+            "sms:displayName": "nanoparticles",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:8",
+            "@id": "bts:Smallmolecule",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "8",
+            "rdfs:label": "Smallmolecule",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:DNA"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "8",
+            "sms:displayName": "small molecule",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:9",
+            "@id": "bts:Mg/mL",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "9",
+            "rdfs:label": "Mg/mL",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:ConcentrationMaterialUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "9",
+            "sms:displayName": "mg/mL",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
         {
-            "@id": "bts:10",
+            "@id": "bts:MM",
             "@type": "rdfs:Class",
             "rdfs:comment": "TBD",
-            "rdfs:label": "10",
+            "rdfs:label": "MM",
             "rdfs:subClassOf": [
                 {
-                    "@id": "bts:ProgressReportNumber"
+                    "@id": "bts:ConcentrationMaterialUnit"
                 }
             ],
             "schema:isPartOf": {
                 "@id": "http://schema.biothings.io"
             },
-            "sms:displayName": "10",
+            "sms:displayName": "mM",
             "sms:required": "sms:false",
             "sms:validationRules": []
         },
diff --git a/modules/Assay/Assay.csv b/modules/Assay/Assay.csv
index ffc12060..e0192bc3 100644
--- a/modules/Assay/Assay.csv
+++ b/modules/Assay/Assay.csv
@@ -94,3 +94,6 @@ Optical Coherence Tomography,"Optical Coherence Tomography (OCT) combines the pr
 CUT&RUN,"Cleavage Under Targets and Release Using Nuclease (CUT&RUN) is a chromatin profiling strategy in which antibody-targeted controlled cleavage by micrococcal nuclease releases specific protein-DNA complexes into the supernatant for paired-end DNA sequencing. (doi:10.7554/eLife.21856)",,,FALSE,,assay,,,,CUT_RUN,Class,Assay,Assay,Epigenetics_Assay,,,
 3D Imaging,"Technique to produce 3D images to visualize important structures in great detail. To produce 3D images, many scans are made, and then combined by computers to produce a 3D model, which can then be manipulated. 3D ultrasounds are produced using a somewhat similar technique.",,Assay,FALSE,http://purl.obolibrary.org/obo/NCIT_C18485,assay,,,,3D_Imaging,Class,Assay,Assay,Imaging_Assay,,,
 High Frequency Ultrasound,"High frequency ultrasound (HFUS) is an imaging modality that can give greater resolution of surface changes in skin (review in PMID:24583666)",,Assay,FALSE,,assay,,,,High_Frequency_Ultrasound,Class,Assay,Assay,Imaging_Assay,,,
+Dynamic Light Scattering,"Dynamic Light Scattering (DLS), also known as photocorrelation spectroscopy, is a method for determining the size distribution of a sample of small particles in solution by illuminating the sample with a light source (usually a laser) and measuring the time-dependent fluctuations in the intensity of the scattered light caused by Brownian motion.",,Assay,FALSE,http://purl.obolibrary.org/obo/CHMO_0000167,assay,,,,Dynamic_Light_Scattering,Class,Assay,Assay,Light_Scattering_Assay,,,
+Static Light Scattering,"Static Light Scattering is a method for determining structure by measuring the total or time-averaged scattering intensity of scattered visible light as a function of angle.",,Assay,FALSE,http://purl.obolibrary.org/obo/CHMO_0000180,assay,,,,Static_Light_Scattering,Class,Assay,Assay,Light_Scattering_Assay,,,
+Light Scattering Assay,"A method for determining structure by measuring the change in direction or energy of scattered visible light. Light is scattered by the electrons surrounding the atomic nuclei in the sample.",,Assay,FALSE,http://purl.obolibrary.org/obo/CHMO_0000166,assay,,,,Light_Scattering_Assay,Class,Assay,Assay,Spectroscopy,,,
diff --git a/modules/Assay/annotationProperty.csv b/modules/Assay/annotationProperty.csv
index b05bedef..5d223a31 100644
--- a/modules/Assay/annotationProperty.csv
+++ b/modules/Assay/annotationProperty.csv
@@ -1,6 +1,6 @@
 Attribute,Description,Valid Values,DependsOn,Required,Source,Parent,Properties,DependsOn Component,Validation Rules,.ID,.Type,.Module,.Root,.SubOf,.Range,.Cardinality,.EditorNote
 drugScreenType,String describing general class of drug screen,"singleMolecule, smallMoleculeLibraryScreen, combinationLibraryScreen, combinationScreen",,FALSE,,compoundScreen,,,,drugScreenType,Property,Assay,annotationProperty,,,,
-assay,The technology used to generate the data in this file,"elevated plus maze test, open field test, rotarod performance test, mRNAcounts, high content screen, Immunocytochemistry, immunofluorescence, autoradiography, electrochemiluminescence, Real Time PCR, in vivo tumor growth, scale, Blood Chemistry Measurement, in vivo bioluminescence, immunohistochemistry, NOMe-Seq, FIA-MSMS, UPLC-MSMS, HPLC-MSMS, liquid chromatography-electrochemical detection, rnaSeq, mirnaSeq, LC-MSMS, LC-MS, lncrnaSeq, Whole Exome Sequencing, Sanger sequencing, ChIPSeq, rnaArray, snpArray, methylationArray, mirnaArray, bisulfiteSeq, ATACSeq, HI-C, errBisulfiteSeq, ISOSeq, westernBlot, wholeGenomeSeq, polymeraseChainReaction, cellViabilityAssay, atomicForceMicroscopy, brightfieldMicroscopy, tractionForceMicroscopy, nextGenerationTargetedSequencing, jumpingLibrary, MIB/MS, scCGIseq, MudPIT, questionnaire, DNA optical mapping, oxBS-Seq, Ribo-Seq, Positron Emission Tomography, RPPA, ELISA, LTP, LFP, whole-cell patch clamp, sandwich ELISA, Laser Speckle Imaging, Genotyping, TMT quantitation, label free mass spectrometry, cell count, reporter gene assay, Single Cell RNA Sequencing, spatial transcriptomics, Conventional MRI, Functional MRI, Magnetic Resonance Spectroscopy, 2D Incucyte, 2D CellTiter-Glo, 3D microtissue viability, in vivo PDX viability, 2D AlamarBlue fluorescence, 2D AlamarBlue absorbance, rheometry, FTIR Spectroscopy, differential scanning calorimetry, Gel filtration chromatography, Massively Parallel Reporter Assay,Riccardi and Ablon scales,Spatial Frequency Domain Imaging,Optical Coherence Tomography,CUT&RUN,High Frequency Ultrasound, 3D Imaging",,TRUE,,experimentalData,,,,assayType,Property,Assay,annotationProperty,,Assay,one,
+assay,The technology used to generate the data in this file,"elevated plus maze test, open field test, rotarod performance test, mRNAcounts, high content screen, Immunocytochemistry, immunofluorescence, autoradiography, electrochemiluminescence, Real Time PCR, in vivo tumor growth, scale, Blood Chemistry Measurement, in vivo bioluminescence, immunohistochemistry, NOMe-Seq, FIA-MSMS, UPLC-MSMS, HPLC-MSMS, liquid chromatography-electrochemical detection, rnaSeq, mirnaSeq, LC-MSMS, LC-MS, lncrnaSeq, Whole Exome Sequencing, Sanger sequencing, ChIPSeq, rnaArray, snpArray, methylationArray, mirnaArray, bisulfiteSeq, ATACSeq, HI-C, errBisulfiteSeq, ISOSeq, westernBlot, wholeGenomeSeq, polymeraseChainReaction, cellViabilityAssay, atomicForceMicroscopy, brightfieldMicroscopy, tractionForceMicroscopy, nextGenerationTargetedSequencing, jumpingLibrary, MIB/MS, scCGIseq, MudPIT, questionnaire, DNA optical mapping, oxBS-Seq, Ribo-Seq, Positron Emission Tomography, RPPA, ELISA, LTP, LFP, whole-cell patch clamp, sandwich ELISA, Laser Speckle Imaging, Genotyping, TMT quantitation, label free mass spectrometry, cell count, reporter gene assay, Single Cell RNA Sequencing, spatial transcriptomics, Conventional MRI, Functional MRI, Magnetic Resonance Spectroscopy, 2D Incucyte, 2D CellTiter-Glo, 3D microtissue viability, in vivo PDX viability, 2D AlamarBlue fluorescence, 2D AlamarBlue absorbance, rheometry, FTIR Spectroscopy, differential scanning calorimetry, Gel filtration chromatography, Massively Parallel Reporter Assay,Riccardi and Ablon scales,Spatial Frequency Domain Imaging,Optical Coherence Tomography,CUT&RUN,High Frequency Ultrasound, 3D Imaging,Dynamic Light Scattering,Static Light Scattering",,TRUE,,experimentalData,,,,assayType,Property,Assay,annotationProperty,,Assay,one,
 platform,"A sequencing platform, microscope, spectroscope/plate reader, or other platform for collecting data.","Illumina HiSeq 3000, Illumina HiSeq 2500, Illumina HiSeq 4000, Illumina NextSeq 500, Illumina HiSeq 2000, Illumina MiSeq, Zeiss LSM 980, Affymetrix Genome-Wide Human SNP 5.0 Array, Affymetrix Genome-Wide Human SNP 6.0 Array, PacBio RS II, Illumina Genome Analyzer IIx, Illumina HumanOmni1-Quadv1.0, Illumina 1M, Illumina h650, Illumina Omni2pt5M, Illumina Omni5M, Illumina MouseWG-6 v2.0 expression beadchip, Perlegen 300Karray, Agilent 44Karray, Illumina WholeGenome DASL, Illumina HumanHap300, Nanostring Counter, LTQ Orbitrap XL, Illumina HumanMethylation450, Illumina Infinium MethylationEPIC BeadChip, Affymetrix U133AB, Affymetrix Human Gene 1.0 ST Array, Affymetrix Human Genome U133 Plus 2.0 Array, Illumina HiSeq X, Bionano Irys, Infinium HumanOmniExpressExome, Illumina NextSeq 550, Illumina NextSeq 1000, Illumina NextSeq 2000, PacBio Sequel IIe System, PacBio Sequel II System, Nanostring GeoMx, LI-COR Odyssey CLx, Spectramax M Series, Olympus DP80, Orbitrap Fusion Lumos Tribrid, Illumina NovaSeq 6000, Chromium X,EnVision 2103 Multiplate Reader,Vectra H1 3D Imaging System,Vevo 3100 Imaging System,10x Visium Spatial Gene Expression,Cherry Imaging TRACE Platform,Cherry Imaging FACE Platform,LifeViz Micro System,LifeViz Infinity System",,FALSE,https://docs.gdc.cancer.gov/Data_Dictionary/viewer/#?view=table-definition-view&id=read_group&anchor=platform,experimentalData,,,,platform,Property,Assay,annotationProperty,,Platform,,
 targetCaptureKitID,"A unique identifier for the kit used to construct a genomic library using target capture-based techniques, which should be composed of the vendor name, kit name and kit version.",,,TRUE,http://purl.obolibrary.org/obo/NCIT_C177583,experimentalData,,,,targetCaptureKitID,Property,Assay,annotationProperty,,,,"For WES processing, the target BED used could be provided based on the target capture kit."
 libraryID,,,,TRUE,,experimentalData,,,,libraryID,Property,Assay,annotationProperty,,,,
diff --git a/modules/Biosample/Body_Part.csv b/modules/Sample/Body_Part.csv
similarity index 100%
rename from modules/Biosample/Body_Part.csv
rename to modules/Sample/Body_Part.csv
diff --git a/modules/Biosample/Cell.csv b/modules/Sample/Cell.csv
similarity index 100%
rename from modules/Biosample/Cell.csv
rename to modules/Sample/Cell.csv
diff --git a/modules/Biosample/Diagnosis.csv b/modules/Sample/Diagnosis.csv
similarity index 100%
rename from modules/Biosample/Diagnosis.csv
rename to modules/Sample/Diagnosis.csv
diff --git a/modules/Biosample/Disease.csv b/modules/Sample/Disease.csv
similarity index 100%
rename from modules/Biosample/Disease.csv
rename to modules/Sample/Disease.csv
diff --git a/modules/Biosample/Genotype.csv b/modules/Sample/Genotype.csv
similarity index 100%
rename from modules/Biosample/Genotype.csv
rename to modules/Sample/Genotype.csv
diff --git a/modules/Sample/Material.csv b/modules/Sample/Material.csv
new file mode 100644
index 00000000..0008acca
--- /dev/null
+++ b/modules/Sample/Material.csv
@@ -0,0 +1,3 @@
+Attribute,Description,Valid Values,DependsOn,Required,Source,Parent,Properties,DependsOn Component,Validation Rules,.ID,.Type,.Module,.Root,.SubOf,.Range,.Cardinality,.EditorNote
+Polymeric nanoparticles,"Polymeric nanoparticles (PNPs) are solid and spherical (in most cases) structures prepared from natural or synthetic polymers with drug delivery being known to be one of the most important biomedical applications (reference: Hirvonen et al., Nanoengineered Biomaterials for Advanced Drug Delivery, 2020)","","",FALSE,"",,materialType,"","",Polymeric_Nanoparticles,Class,Sample,Material,"","","",""
+DNA,"DNA (deoxyribonucleic acid) is a polymer of nucleotides and is the genetic material in organisms and some viruses.","","",FALSE,"",,materialType,"","",DNA,Class,Sample,Material,"","","",""
diff --git a/modules/Biosample/Model_System.csv b/modules/Sample/Model_System.csv
similarity index 100%
rename from modules/Biosample/Model_System.csv
rename to modules/Sample/Model_System.csv
diff --git a/modules/Biosample/Sex.csv b/modules/Sample/Sex.csv
similarity index 100%
rename from modules/Biosample/Sex.csv
rename to modules/Sample/Sex.csv
diff --git a/modules/Biosample/Species.csv b/modules/Sample/Species.csv
similarity index 100%
rename from modules/Biosample/Species.csv
rename to modules/Sample/Species.csv
diff --git a/modules/Biosample/Specimen_Processing.csv b/modules/Sample/Specimen_Processing.csv
similarity index 100%
rename from modules/Biosample/Specimen_Processing.csv
rename to modules/Sample/Specimen_Processing.csv
diff --git a/modules/Biosample/Specimen_State.csv b/modules/Sample/Specimen_State.csv
similarity index 100%
rename from modules/Biosample/Specimen_State.csv
rename to modules/Sample/Specimen_State.csv
diff --git a/modules/Biosample/Tissue.csv b/modules/Sample/Tissue.csv
similarity index 100%
rename from modules/Biosample/Tissue.csv
rename to modules/Sample/Tissue.csv
diff --git a/modules/Biosample/Tumor.csv b/modules/Sample/Tumor.csv
similarity index 100%
rename from modules/Biosample/Tumor.csv
rename to modules/Sample/Tumor.csv
diff --git a/modules/Biosample/annotationProperty.csv b/modules/Sample/annotationProperty.csv
similarity index 82%
rename from modules/Biosample/annotationProperty.csv
rename to modules/Sample/annotationProperty.csv
index b9cdc508..a133c759 100644
--- a/modules/Biosample/annotationProperty.csv
+++ b/modules/Sample/annotationProperty.csv
@@ -1,6 +1,5 @@
 Attribute,Description,Valid Values,DependsOn,Required,Source,Parent,Properties,DependsOn Component,Validation Rules,.ID,.Type,.Module,.Root,.SubOf,.Range,.Cardinality,.EditorNote
-tumorType,The type of tumor that the biospecimen used to generate the data were collected from.,"Teratoma, Cutaneous Neurofibroma, Subcutaneous Neurofibroma, Plexiform Neurofibroma, Atypical Neurofibroma, Malignant Peripheral Nerve Sheath Tumor, Glioma, Low-Grade Glioma NOS, Pilocytic Astrocytoma, Atypical Pilocytic Astrocytoma, Pilomyxoid Astrocytoma, Diffuse Astrocytoma, Glioblastoma Multiforme, Anaplastic Pilocytic Astrocytoma, Pleomorphic Xanthoastrocytoma, Oligoastrocytoma, High-Grade Glioma NOS, Unknown, Anaplastic Astrocytoma, Glioblastoma, Schwannoma, Meningioma, Massive Soft 
-Neurofibroma, Diffuse Infiltrating Neurofibroma, Localized Neurofibroma, Neurofibroma with Degenerative Atypia, Neurofibroma, Anaplastic Pleomorphic Xanthoastrocytoma, Ganglioglioma, Anaplastic Ganglioglioma, Optic Pathway Glioma, Not Applicable,Colorectal Carcinoma,Recurrent MPNST,Juvenile Myelomonocytic Leukemia,Sarcoma,Fibromatosis,Fibrosarcoma,Necrotic Neoplasm,Hemorrhagic Neoplasm,NF1-Associated Tumor,NF2-Associated Tumor",,FALSE,Sage Bionetworks,cancer,,,,tumorType,Property,Biosample,annotationProperty,biosampleAnnotation,Tumor,,
+tumorType,The type of tumor that the biospecimen used to generate the data were collected from.,"Teratoma, Cutaneous Neurofibroma, Subcutaneous Neurofibroma, Plexiform Neurofibroma, Atypical Neurofibroma, Malignant Peripheral Nerve Sheath Tumor, Glioma, Low-Grade Glioma NOS, Pilocytic Astrocytoma, Atypical Pilocytic Astrocytoma, Pilomyxoid Astrocytoma, Diffuse Astrocytoma, Glioblastoma Multiforme, Anaplastic Pilocytic Astrocytoma, Pleomorphic Xanthoastrocytoma, Oligoastrocytoma, High-Grade Glioma NOS, Unknown, Anaplastic Astrocytoma, Glioblastoma, Schwannoma, Meningioma, Massive Soft Neurofibroma, Diffuse Infiltrating Neurofibroma, Localized Neurofibroma, Neurofibroma with Degenerative Atypia, Neurofibroma, Anaplastic Pleomorphic Xanthoastrocytoma, Ganglioglioma, Anaplastic Ganglioglioma, Optic Pathway Glioma, Not Applicable,Colorectal Carcinoma,Recurrent MPNST,Juvenile Myelomonocytic Leukemia,Sarcoma,Fibromatosis,Fibrosarcoma,Necrotic Neoplasm,Hemorrhagic Neoplasm,NF1-Associated Tumor,NF2-Associated Tumor",,FALSE,Sage Bionetworks,cancer,,,,tumorType,Property,Biosample,annotationProperty,biosampleAnnotation,Tumor,,
 diagnosis,A diagnosis is the result of a medical investigation to identify a disorder from its signs and symptoms.,"Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis, Unknown, Not Applicable, Sporadic Schwannoma",,FALSE,,experimentalData,,,,diagnosis,Property,Biosample,annotationProperty,,Diagnosis,one,Currently a single NF diagnosis allowed; in the future multiple diagnoses may be allowed for comorbidities.
 bodyPart,"Sample location referring to a named area of the body, inclusive of gross anatomical structures and organ parts. ","head, neck, scalp, leg, pelvis, mesentery, axilla, acetabulum, forearm, muscle, finger, thoracic spine, groin, back, iliac spine, spine, shoulder, scapula, lymph node, kidney, skin, mammary gland, nerves, brain, blood, breast, colon, lung, liver, prostate, pancreas, ovary, spleen, bone marrow, Bursa Of Fabricius, nose",,FALSE,,experimentalData,,,,bodyPart,Property,Biosample,annotationProperty,,Body_Part,,
 organ,A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues. An organ is part of an anatomic system or a body region.,"lymph node, kidney, skin, mammary gland, nerves, brain, blood, breast, colon, lung, liver, prostate, pancreas, ovary, spleen, bone marrow, Bursa Of Fabricius, nose, Eye",,FALSE,,experimentalData,,,,organ,Property,Biosample,annotationProperty,,Organ,,
@@ -26,3 +25,11 @@ age,A numeric value representing age of the individual. Use with ageUnit.,,ageUn
 ageUnit,"A time unit that can be used with a given age value, e.g. years.","days, months, years",,FALSE,Sage Bionetworks,,,,,ageUnit,Property,Biosample,annotationProperty,biosampleAnnotation,,,
 bioSampleUsed,The biosample used.,,,,,,,,,,,,,,,,
 isXenograft,Whether or not sample source is a xenograft (Yes; No),"Yes, No",,TRUE,,experimentalData,,,,isXenograft,DataProperty,Biosample,annotationProperty,,,,
+sourceName," identifies the source from where the sample is derived. If the sample assayed is a nanoparticle sample or some chemical substance not derived from a biological material, then the corresponding source name should refer to the starting sample that was modified by a protocol for the assay.","",,TRUE,,sourceName,,,,sourceName,Property,Sample,annotationProperty,,,,
+sampleType,"Type of sample","",,FALSE,,sampleType,,,,molecularSpecies,Property,Sample,annotationProperty,,,,"Not used directly in template since each template already implicitly assumes either a biospecimen sample or chemical sample; this is a super-property for organization purposes"
+materialType,"Type of material in the characterization","nanoparticles,polymeric nanoparticles,small molecule,DNA",,FALSE,,sampleType,,,,materialType,Property,Material,annotationProperty,,,,
+pH,"Numeric value for pH sample parameter","",,FALSE,,parameter,,,,pH,Property,Sample,annotationProperty,,,,
+concentrationMaterial,"Numeric value for concentration of the material","",,FALSE,,parameter,,,,concentration,DataProperty,Sample,annotationProperty,,,,
+concentrationMaterialUnit,"Unit used for the material concentration, e.g. mg/mL","mg/mL,mM",,FALSE,,parameter,,,,concentrationUnit,Property,Sample,annotationProperty,,,,
+concentrationNaCl,"Numeric value for NaCl concentration","",,FALSE,,parameter,,,,concentrationNaCl,DataProperty,Sample,annotationProperty,,,,
+concentrationNaClUnit,"Unit used for the NaCl concentration, e.g. mM","mg/mL,mM",,FALSE,,parameter,,,,concentrationNaClUnit,Property,Sample,annotationProperty,,,,
diff --git a/modules/Template/Template.csv b/modules/Template/Template.csv
index 1664c562..40b5ee65 100644
--- a/modules/Template/Template.csv
+++ b/modules/Template/Template.csv
@@ -33,3 +33,4 @@ experimentComponent,Template component for describing core experimental paramete
 genePerturbComponent,Template component for adding genetic perturbation metadata. This applies only to some assays and does not make sense with e.g. behavioral assays.,"genePerturbed,genePerturbationType,genePerturbationTechnology","genePerturbed,genePerturbationType,genePerturbationTechnology",FALSE,Sage Bionetworks,template,,,,Gene_Perturb_Component,Class,Template,TemplateComponent,,,,
 fileComponent,Template component for describing some file on the NF-OSI Synapse platform.,"Filename,entityId,fileFormat,resourceType","Filename,entityId,fileFormat,resourceType",FALSE,Sage Bionetworks,template,,,,File_Component,Class,Template,TemplateComponent,,,,
 ngsComponent,Template component capturing Next Gen Sequencing/genomics attributes.,"runType,readPair,isStranded,readPairOrientation,readStrandOrigin,libraryPrep,libraryPreparationMethod,dissociationMethod,readLength,nucleicAcidSource","runType,readPair,isStranded,readPairOrientation,readStrandOrigin,libraryPrep,libraryPreparationMethod,dissociationMethod,readLength,nucleicAcidSource",FALSE,Sage Bionetworks,template,,,,NGS_Component,Class,Template,TemplateComponent,,,,
+DynamicLightScatteringTemplate,"Template for dynamic light scattering data adapted from ISA-TAB-Nano specs (https://wiki.nci.nih.gov/display/icr/isa-tab-nano)",,"Component,Filename,resourceType,dataType,assay,materialType,pH,concentrationMaterial,concentrationMaterialUnit,concentrationNaCl,concentrationNaClUnit",FALSE,Sage Bionetworks,template,,,,Dynamic_Light_Scattering_Template,Class,Template,Template,,,,
diff --git a/tests/generate_excel.sh b/tests/generate_excel.sh
new file mode 100755
index 00000000..5b3b89b2
--- /dev/null
+++ b/tests/generate_excel.sh
@@ -0,0 +1,5 @@
+#!/bin/bash
+# Test generate excel manifests -- artifacts can be published as a bundle for convenient reference and offline usage when needed  
+
+mkdir publish
+schematic manifest -c config.yml get -dt 'DynamicLightScatteringTemplate' --jsonld NF.jsonld  --output_xlsx publish/DynamicLightScatteringTemplate.xlsx