diff --git a/CHANGELOG.md b/CHANGELOG.md
index 732d52903a..ce479c29bb 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,7 @@
 
 ### Template
 
+- Remove fasta default from nextflow.config ([#2828](https://github.com/nf-core/tools/pull/2828))
 - Update templates to use nf-core/setup-nextflow v2
 
 ### Linting
diff --git a/nf_core/pipeline-template/nextflow.config b/nf_core/pipeline-template/nextflow.config
index 17e75f18a4..2f9b349916 100644
--- a/nf_core/pipeline-template/nextflow.config
+++ b/nf_core/pipeline-template/nextflow.config
@@ -18,7 +18,6 @@ params {
     genome                     = null
     igenomes_base              = 's3://ngi-igenomes/igenomes/'
     igenomes_ignore            = false
-    fasta                      = null
     {%- endif -%}
 
     // MultiQC options