diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 26baa88..7b25fa1 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -56,9 +56,9 @@ jobs:
     
       - name: Install pybigtools
         run: |
-          pip install maturin pytest
+          pip install maturin
           cd pybigtools
-          pip install -e .
+          pip install -e .[test]
   
       - name: Install
         run: |
diff --git a/pybigtools/pyproject.toml b/pybigtools/pyproject.toml
index 562e4be..cd8225b 100644
--- a/pybigtools/pyproject.toml
+++ b/pybigtools/pyproject.toml
@@ -6,10 +6,34 @@ build-backend = "maturin"
 name = "pybigtools"
 description = "Python bindings to the Bigtools Rust library for high-performance BigWig and BigBed I/O"
 license = { text = "MIT" }
+keywords = [
+    "bigwig",
+    "bigbed",
+    "bbi",
+    "bioinformatics",
+    "genomics",
+    "kent",
+    "ucsc",
+    "rust",
+]
+classifiers = [
+    "Development Status :: 4 - Beta",
+    "Operating System :: OS Independent",
+    "Topic :: Scientific/Engineering :: Bio-Informatics",
+    "Programming Language :: Rust",
+    "Programming Language :: Python",
+    "Programming Language :: Python :: 3",
+]
 dependencies = [
     "numpy"
 ]
 
+[project.optional-dependencies]
+test = [
+    "pytest",
+    "smart_open[http]"
+]
+
 [project.urls]
 homepage = "https://github.com/jackh726/bigtools"
 documentation = "https://bigtools.readthedocs.io"
diff --git a/pybigtools/tests/test_api.py b/pybigtools/tests/test_api.py
index 76184d1..28d1715 100644
--- a/pybigtools/tests/test_api.py
+++ b/pybigtools/tests/test_api.py
@@ -4,6 +4,7 @@
 
 import numpy as np
 import pytest
+import smart_open
 
 import pybigtools
 
@@ -17,12 +18,6 @@ def test_open_close():
     b.close()
     assert pytest.raises(pybigtools.BBIFileClosed, b.chroms)
 
-    # Works with pathlib.Path
-    path = REPO_ROOT / "bigtools/resources/test/valid.bigWig"
-    b = pybigtools.open(path, "r")
-    b.close()
-    assert pytest.raises(pybigtools.BBIFileClosed, b.chroms)
-
     # Files are closed when exiting a context manager
     with pybigtools.open(path, "r") as b:
         pass
@@ -33,6 +28,39 @@ def test_open_close():
     assert pytest.raises(pybigtools.BBIReadError, pybigtools.open, s, "r")
 
 
+def test_open_pathlib_path():
+    path = REPO_ROOT / "bigtools/resources/test/valid.bigWig"
+    with pybigtools.open(path, "r") as b:
+        assert b.chroms() == {"chr17": 83_257_441}
+
+
+def test_open_raw_url():
+    url = "http://genome.ucsc.edu/goldenPath/help/examples/bigLollyExample2.bb"
+    with pybigtools.open(url, "r") as b:
+        assert b.chroms() == {'chr21': 46_709_983}
+
+
+def test_open_filelike():
+    # Regular file
+    with open(REPO_ROOT / "bigtools/resources/test/valid.bigWig", "rb") as f:
+        with pybigtools.open(f, "r") as b:
+            assert b.chroms() == {"chr17": 83_257_441}
+
+    # BytesIO
+    with open(REPO_ROOT / "bigtools/resources/test/valid.bigWig", "rb") as f:
+        bw_bytes = f.read()
+
+    with BytesIO(bw_bytes) as f:
+        with pybigtools.open(f, "r") as b:
+            assert b.chroms() == {"chr17": 83_257_441}
+
+    # Other file-like objects
+    url = "http://genome.ucsc.edu/goldenPath/help/examples/bigWigExample.bw"
+    with smart_open.open(url, "rb") as f:
+        with pybigtools.open(f, "r") as b:
+            assert b.chroms() == {'chr21': 48_129_895}
+
+
 @pytest.fixture
 def bw():
     path = str(REPO_ROOT / "bigtools/resources/test/valid.bigWig")
@@ -77,8 +105,8 @@ def test_chroms(bw, bb):
     assert bb.chroms() == {"chr21": 48_129_895}
 
     # Arg with chrom name => length
-    assert bw.chroms("chr17") == 83257441
-    assert bb.chroms("chr21") == 48129895
+    assert bw.chroms("chr17") == 83_257_441
+    assert bb.chroms("chr21") == 48_129_895
 
     # Missing chrom => KeyError
     pytest.raises(KeyError, bw.chroms, "chr11")