diff --git a/java-life-sciences/CHANGELOG.md b/java-life-sciences/CHANGELOG.md
index 2ad06b560961..3e141e3ea32a 100644
--- a/java-life-sciences/CHANGELOG.md
+++ b/java-life-sciences/CHANGELOG.md
@@ -1,5 +1,12 @@
 # Changelog
 
+## [0.5.7](https://github.com/googleapis/java-life-sciences/compare/v0.5.6...v0.5.7) (2022-10-05)
+
+
+### Bug Fixes
+
+* update protobuf to v3.21.7 ([1479321](https://github.com/googleapis/java-life-sciences/commit/1479321e19d58a59b28613911c810015d7e9d629))
+
 ## [0.5.6](https://github.com/googleapis/java-life-sciences/compare/v0.5.5...v0.5.6) (2022-10-03)
 
 
diff --git a/java-life-sciences/google-cloud-life-sciences-bom/pom.xml b/java-life-sciences/google-cloud-life-sciences-bom/pom.xml
index c179b8664e9e..095a191eb542 100644
--- a/java-life-sciences/google-cloud-life-sciences-bom/pom.xml
+++ b/java-life-sciences/google-cloud-life-sciences-bom/pom.xml
@@ -3,7 +3,7 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences-bom</artifactId>
-  <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <packaging>pom</packaging>
   <parent>
     <groupId>com.google.cloud</groupId>
@@ -56,17 +56,17 @@
       <dependency>
         <groupId>com.google.cloud</groupId>
         <artifactId>google-cloud-life-sciences</artifactId>
-        <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+        <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.7</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.7</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
     </dependencies>
   </dependencyManagement>
diff --git a/java-life-sciences/google-cloud-life-sciences/pom.xml b/java-life-sciences/google-cloud-life-sciences/pom.xml
index 41f6e3ad77b3..da4a0536eeb4 100644
--- a/java-life-sciences/google-cloud-life-sciences/pom.xml
+++ b/java-life-sciences/google-cloud-life-sciences/pom.xml
@@ -3,7 +3,7 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences</artifactId>
-  <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <packaging>jar</packaging>
   <name>Google Cloud Life Sciences</name>
   <url>https://github.com/googleapis/java-life-sciences</url>
@@ -11,7 +11,7 @@
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <properties>
     <site.installationModule>google-cloud-life-sciences</site.installationModule>
diff --git a/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml b/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml
index 5df9a7cca833..16cf7f480ba7 100644
--- a/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml
+++ b/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml
@@ -4,13 +4,13 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.api.grpc</groupId>
   <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-  <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+  <version>0.5.7</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
   <name>grpc-google-cloud-life-sciences-v2beta</name>
   <description>GRPC library for google-cloud-life-sciences</description>
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <dependencies>
     <dependency>
diff --git a/java-life-sciences/pom.xml b/java-life-sciences/pom.xml
index 79f12ae584ef..fbbd270f5e28 100644
--- a/java-life-sciences/pom.xml
+++ b/java-life-sciences/pom.xml
@@ -4,7 +4,7 @@
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences-parent</artifactId>
   <packaging>pom</packaging>
-  <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <name>Google Cloud Life Sciences Parent</name>
   <url>https://github.com/googleapis/java-life-sciences</url>
   <description>
@@ -60,17 +60,17 @@
       <dependency>
         <groupId>com.google.cloud</groupId>
         <artifactId>google-cloud-life-sciences</artifactId>
-        <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+        <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.7</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.5.7</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
 
       <dependency>
diff --git a/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml b/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml
index 3b7c7e0b5b3c..1cb2eea729c6 100644
--- a/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml
+++ b/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml
@@ -4,13 +4,13 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.api.grpc</groupId>
   <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-  <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+  <version>0.5.7</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
   <name>proto-google-cloud-life-sciences-v2beta</name>
   <description>Proto library for google-cloud-life-sciences</description>
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.5.7-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.5.7</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <dependencies>
     <dependency>
diff --git a/java-life-sciences/versions.txt b/java-life-sciences/versions.txt
index 2545b2bb7ca0..606104236961 100644
--- a/java-life-sciences/versions.txt
+++ b/java-life-sciences/versions.txt
@@ -1,6 +1,6 @@
 # Format:
 # module:released-version:current-version
 
-google-cloud-life-sciences:0.5.6:0.5.7-SNAPSHOT
-grpc-google-cloud-life-sciences-v2beta:0.5.6:0.5.7-SNAPSHOT
-proto-google-cloud-life-sciences-v2beta:0.5.6:0.5.7-SNAPSHOT
+google-cloud-life-sciences:0.5.7:0.5.7
+grpc-google-cloud-life-sciences-v2beta:0.5.7:0.5.7
+proto-google-cloud-life-sciences-v2beta:0.5.7:0.5.7