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Updated version of edgeR throws "norm factors don't multiply to 1" warnings #13

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lianos opened this issue Mar 3, 2020 · 0 comments
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lianos commented Mar 3, 2020

The edgeR update from 3.28.0 to 3.28.1 included some more sanity checks of library.size on norm.factors columns.

Now many of our unit tests throw warnings about fishy norm.factors:

  • test-as.FacileDataSet.R:27: warning: exampleFacileDataSet -> DGELists -> as.FacileDataSet norm factors don't multiply to 1
  • test-assay-normalization.R:18: warning: Normalization of rnaseq data is equivalent to edgeR::cpm norm factors don't multiply to 1
  • test-bioc-assay-containers.R:(18, 45, 46, 65): warning: fetch_assay_data results converted to DGEList norm factors don't multiply to 1
@lianos lianos self-assigned this Mar 3, 2020
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