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Change Log

Unreleased changes

Reactome v71

Summary for Reactome v71 pathways that are not inferred

Pathways
count description
2,492 total pathways
508 is in disease
32 top-level pathway
999 (40.09%) pathways have figures
count description
999 generated figure or hand-drawn figurehttps://t.co/7xByA9uKKa?amp=1
826 generated figure
173 hand-drawn figure
2,302 pathways (92.38%) have a publication:
Publications summary key:
  P -> PubMed ID
  B -> Book
  U -> URL
count publication keys
2,191 P..
67 PB.
34 .B.
7 P.U
2 ..U
1 PBU

Added:

  • One species: Clostridium perfringens (cpe, taxid=1502)

Changed

  • Number instances increased for relationships involving PhysicalEntity and Event except:
    • Small decrease for:
      • (PhysicalEntity)-[repeatedUnit]->(PhysicalEntity)
    • No change for:
      • (PhysicalEntity)-[entityOnOtherCell]->(PhysicalEntity)
      • (Event)-[reverseReaction]->(Event)
      • (Event)-[entityOnOtherCell]->(PhysicalEntity)
  • (Person):
    • Added about 4,000 more people (Person)
    • Removed BA Brown-Kipphut and MD Maines
  • (Figure):
    • Number of figures reduced to 785 from 808
    • Removed figure author, Marcela Tello-Ruiz
    • Seven more pathways have figures
  • (Summation):
    • Added ~50 Pathway Summations
  • Diseases: Added 47 and removed 4
  • Node instances that were reduced:
Node name from to
GO_CellularComponent 338 304
Depolymerisation 38 31
OtherEntity 334 330
Polymer 1,518 1,507
GenomeEncodedEntity 6,909 5,915
ReferenceDNASequence 533,570 475,150
OtherEntity 334 330
TopLevelPathway 389 374

Reactome v69

Release 2019-07-29 v69.00

Added:

  • New relationships:
    • regulation
    • regulationReference
    • catalystActivityReference
    • surroundedBy
  • New Classes:
    • ControlReference
      • CatalystActivityReference
      • RegulationReference
  • New relationships on ReactionLikeEvent to new ControlReference classes
  • New optional parameter, stoichiometryKnown, to Complex
  • New optional parameter, pubmed, to UndirectedInteraction
  • New relationship, surroundedBy, to GO_CellularComponent

Removed:

  • Removed relationships from GO_BiologicalProcess, GO_MolecularFunction, :
    • regulate
    • positivelyRegulate
    • negativelyRegulate

Copyright (C) 2018-present, DV Klopfenstein. All rights reserved.