diff --git a/.github/workflows/ccruntime_e2e.yaml b/.github/workflows/ccruntime_e2e.yaml
index b82e6bba..1e2626fe 100644
--- a/.github/workflows/ccruntime_e2e.yaml
+++ b/.github/workflows/ccruntime_e2e.yaml
@@ -25,6 +25,13 @@ jobs:
           - "az-ubuntu-2004"
           - "az-ubuntu-2204"
           - "s390x"
+          - "tdx"
+        exclude:
+          instance: "tdx"
+          runtimeclass: "kata-qemu"
+        include:
+          instance: "tdx"
+          runtimeclass: "kata-qemu-tdx"
     runs-on: ${{ matrix.instance }}
     steps:
       - name: Take a pre-action for self-hosted runner