diff --git a/brainglobe_utils/qtpy/dialog.py b/brainglobe_utils/qtpy/dialog.py
new file mode 100644
index 0000000..9ba3cde
--- /dev/null
+++ b/brainglobe_utils/qtpy/dialog.py
@@ -0,0 +1,29 @@
+from qtpy.QtWidgets import QMessageBox, QWidget
+
+
+def display_warning(widget: QWidget, title: str, message: str) -> bool:
+    """
+    Display a warning in a pop-up that can be accepted or dismissed
+    """
+    message_reply = QMessageBox.question(
+        widget,
+        title,
+        message,
+        QMessageBox.Yes | QMessageBox.Cancel,
+    )
+    if message_reply == QMessageBox.Yes:
+        return True
+    else:
+        return False
+
+
+def display_info(widget, title, message):
+    """
+    Display information in a pop-up that can only be accepted
+    """
+    QMessageBox.information(
+        widget,
+        title,
+        message,
+        QMessageBox.Ok,
+    )
diff --git a/brainglobe_utils/qtpy/interaction.py b/brainglobe_utils/qtpy/interaction.py
new file mode 100644
index 0000000..a5ac1d8
--- /dev/null
+++ b/brainglobe_utils/qtpy/interaction.py
@@ -0,0 +1,138 @@
+from typing import Callable, List, Optional, Tuple
+
+from qtpy.QtWidgets import (
+    QCheckBox,
+    QComboBox,
+    QDoubleSpinBox,
+    QLabel,
+    QLayout,
+    QPushButton,
+    QSpinBox,
+)
+
+
+def add_button(
+    label: str,
+    layout: QLayout,
+    connected_function: Callable,
+    *,
+    row: int = 0,
+    column: int = 0,
+    visibility: bool = True,
+    minimum_width: int = 0,
+    alignment: str = "center",
+    tooltip: Optional[str] = None,
+) -> QPushButton:
+    """
+    Add a button to *layout*.
+    """
+    button = QPushButton(label)
+    if alignment == "center":
+        pass
+    elif alignment == "left":
+        button.setStyleSheet("QPushButton { text-align: left; }")
+    elif alignment == "right":
+        button.setStyleSheet("QPushButton { text-align: right; }")
+
+    button.setVisible(visibility)
+    button.setMinimumWidth(minimum_width)
+
+    if tooltip:
+        button.setToolTip(tooltip)
+
+    layout.addWidget(button, row, column)
+    button.clicked.connect(connected_function)
+    return button
+
+
+def add_checkbox(
+    layout, default, label, row: int = 0, column: int = 0, tooltip=None
+):
+    box = QCheckBox()
+    box.setChecked(default)
+    if tooltip:
+        box.setToolTip(tooltip)
+    layout.addWidget(QLabel(label), row, column)
+    layout.addWidget(box, row, column + 1)
+    return box
+
+
+def add_float_box(
+    layout,
+    default,
+    minimum,
+    maximum,
+    label,
+    step,
+    row: int = 0,
+    column: int = 0,
+    tooltip=None,
+):
+    box = QDoubleSpinBox()
+    box.setMinimum(minimum)
+    box.setMaximum(maximum)
+    box.setValue(default)
+    box.setSingleStep(step)
+    if tooltip:
+        box.setToolTip(tooltip)
+    layout.addWidget(QLabel(label), row, column)
+    layout.addWidget(box, row, column + 1)
+    return box
+
+
+def add_int_box(
+    layout,
+    default,
+    minimum,
+    maximum,
+    label,
+    row: int = 0,
+    column: int = 0,
+    tooltip=None,
+):
+    box = QSpinBox()
+    box.setMinimum(minimum)
+    box.setMaximum(maximum)
+    # Not always set if not after min & max
+    box.setValue(default)
+    if tooltip:
+        box.setToolTip(tooltip)
+    layout.addWidget(QLabel(label), row, column)
+    layout.addWidget(box, row, column + 1)
+    return box
+
+
+def add_combobox(
+    layout: QLayout,
+    label: str,
+    items: List[str],
+    row: int = 0,
+    column: int = 0,
+    label_stack: bool = False,
+    callback=None,
+    width: int = 150,
+) -> Tuple[QComboBox, Optional[QLabel]]:
+    """
+    Add a selection box to *layout*.
+    """
+    if label_stack:
+        combobox_row = row + 1
+        combobox_column = column
+    else:
+        combobox_row = row
+        combobox_column = column + 1
+    combobox = QComboBox()
+    combobox.addItems(items)
+    if callback:
+        combobox.currentIndexChanged.connect(callback)
+    combobox.setMaximumWidth = width
+
+    if label is not None:
+        combobox_label = QLabel(label)
+        combobox_label.setMaximumWidth = width
+        layout.addWidget(combobox_label, row, column)
+    else:
+        combobox_label = None
+
+    layout.addWidget(combobox, combobox_row, combobox_column)
+    return combobox, combobox_label
diff --git a/tests/tests/test_qtpy/test_interaction.py b/tests/tests/test_qtpy/test_interaction.py
new file mode 100644
index 0000000..68fd1f3
--- /dev/null
+++ b/tests/tests/test_qtpy/test_interaction.py
@@ -0,0 +1,39 @@
+import pytest
+from qtpy.QtWidgets import QGridLayout
+
+from brainglobe_utils.qtpy.interaction import add_button, add_combobox
+
+
+@pytest.mark.parametrize("label_stack", [True, False])
+@pytest.mark.parametrize("label", ["A label", None])
+def test_add_combobox(label, label_stack):
+    """
+    Smoke test for add_combobox for all conditional branches
+    """
+    layout = QGridLayout()
+    combobox = add_combobox(
+        layout,
+        row=0,
+        label=label,
+        items=["item 1", "item 2"],
+        label_stack=label_stack,
+    )
+    assert combobox is not None
+
+
+@pytest.mark.parametrize(
+    argnames="alignment", argvalues=["center", "left", "right"]
+)
+def test_add_button(alignment):
+    """
+    Smoke tests for add_button for all conditional branches
+    """
+    layout = QGridLayout()
+    button = add_button(
+        layout=layout,
+        connected_function=lambda: None,
+        label="A button",
+        row=0,
+        alignment=alignment,
+    )
+    assert button is not None