diff --git a/packages/apollo-server-plugin-response-cache/src/ApolloServerPluginResponseCache.ts b/packages/apollo-server-plugin-response-cache/src/ApolloServerPluginResponseCache.ts
index 71da54b6fc4..cce84c14f59 100644
--- a/packages/apollo-server-plugin-response-cache/src/ApolloServerPluginResponseCache.ts
+++ b/packages/apollo-server-plugin-response-cache/src/ApolloServerPluginResponseCache.ts
@@ -72,6 +72,12 @@ interface Options<TContext = Record<string, any>> {
     requestContext: GraphQLRequestContext<TContext>,
   ): ValueOrPromise<any>;
 
+  // Define this hook if you want the cache key to use a prefix before the hash
+  // Example: {operationName}:{keyHash}
+  dynamicPrefix?(
+    requestContext: GraphQLRequestContext<TContext>,
+  ): ValueOrPromise<string>;
+
   // If this hook is defined and returns false, the plugin will not read
   // responses from the cache.
   shouldReadFromCache?(
@@ -133,6 +139,8 @@ function isGraphQLQuery(requestContext: GraphQLRequestContext<any>) {
   return requestContext.operation?.operation === 'query';
 }
 
+let dynamicPrefix: string = '';
+
 export default function plugin(
   options: Options = Object.create(null),
 ): ApolloServerPlugin {
@@ -166,7 +174,7 @@ export default function plugin(
               ...baseCacheKey!,
               ...contextualCacheKeyFields,
             });
-            const serializedValue = await cache.get(key);
+            const serializedValue = await cache.get(dynamicPrefix + key);
             if (serializedValue === undefined) {
               return null;
             }
@@ -189,6 +197,10 @@ export default function plugin(
             extraCacheKeyData = await options.extraCacheKeyData(requestContext);
           }
 
+          if (options.dynamicPrefix) {
+            dynamicPrefix = await options.dynamicPrefix(requestContext);
+          }
+
           baseCacheKey = {
             source: requestContext.source!,
             operationName: requestContext.operationName,
@@ -293,7 +305,9 @@ export default function plugin(
             // still calls `cache.set` synchronously (ie, that it writes to
             // InMemoryLRUCache synchronously).
             cache
-              .set(key, serializedValue, { ttl: policyIfCacheable.maxAge })
+              .set(dynamicPrefix + key, serializedValue, {
+                ttl: policyIfCacheable.maxAge,
+              })
               .catch(logger.warn);
           };