diff --git a/fe/fe-core/src/main/java/org/apache/doris/common/NereidsSqlCacheManager.java b/fe/fe-core/src/main/java/org/apache/doris/common/NereidsSqlCacheManager.java
index e6a72d069b4b4f..77f1d929dd5195 100644
--- a/fe/fe-core/src/main/java/org/apache/doris/common/NereidsSqlCacheManager.java
+++ b/fe/fe-core/src/main/java/org/apache/doris/common/NereidsSqlCacheManager.java
@@ -38,6 +38,7 @@
 import org.apache.doris.nereids.SqlCacheContext.ScanTable;
 import org.apache.doris.nereids.StatementContext;
 import org.apache.doris.nereids.analyzer.UnboundVariable;
+import org.apache.doris.nereids.parser.NereidsParser;
 import org.apache.doris.nereids.properties.PhysicalProperties;
 import org.apache.doris.nereids.rules.analysis.ExpressionAnalyzer;
 import org.apache.doris.nereids.rules.analysis.UserAuthentication;
@@ -127,7 +128,7 @@ public void tryAddFeSqlCache(ConnectContext connectContext, String sql) {
         SqlCacheContext sqlCacheContext = sqlCacheContextOpt.get();
         UserIdentity currentUserIdentity = connectContext.getCurrentUserIdentity();
         String key = sqlCacheContext.getCacheKeyType() == CacheKeyType.SQL
-                ? currentUserIdentity.toString() + ":" + sql.trim()
+                ? currentUserIdentity.toString() + ":" + normalizeSql(sql.trim())
                 : currentUserIdentity.toString() + ":" + DebugUtil.printId(sqlCacheContext.getOrComputeCacheKeyMd5());
         if (sqlCaches.getIfPresent(key) == null && sqlCacheContext.getOrComputeCacheKeyMd5() != null
                 && sqlCacheContext.getResultSetInFe().isPresent()) {
@@ -147,7 +148,7 @@ public void tryAddBeCache(ConnectContext connectContext, String sql, CacheAnalyz
         SqlCacheContext sqlCacheContext = sqlCacheContextOpt.get();
         UserIdentity currentUserIdentity = connectContext.getCurrentUserIdentity();
         String key = sqlCacheContext.getCacheKeyType() == CacheKeyType.SQL
-                ? currentUserIdentity.toString() + ":" + sql.trim()
+                ? currentUserIdentity.toString() + ":" + normalizeSql(sql.trim())
                 : currentUserIdentity.toString() + ":" + DebugUtil.printId(sqlCacheContext.getOrComputeCacheKeyMd5());
         if (sqlCaches.getIfPresent(key) == null && sqlCacheContext.getOrComputeCacheKeyMd5() != null) {
             SqlCache cache = (SqlCache) analyzer.getCache();
@@ -168,7 +169,7 @@ public void tryAddBeCache(ConnectContext connectContext, String sql, CacheAnalyz
     /** tryParseSql */
     public Optional<LogicalSqlCache> tryParseSql(ConnectContext connectContext, String sql) {
         UserIdentity currentUserIdentity = connectContext.getCurrentUserIdentity();
-        String key = currentUserIdentity + ":" + sql.trim();
+        String key = currentUserIdentity + ":" + normalizeSql(sql.trim());
         SqlCacheContext sqlCacheContext = sqlCaches.getIfPresent(key);
         if (sqlCacheContext == null) {
             return Optional.empty();
@@ -201,6 +202,10 @@ public Optional<LogicalSqlCache> tryParseSql(ConnectContext connectContext, Stri
         }
     }
 
+    private String normalizeSql(String sql) {
+        return NereidsParser.removeCommentAndTrimBlank(sql);
+    }
+
     private Optional<LogicalSqlCache> tryParseSqlWithoutCheckVariable(
             ConnectContext connectContext, String key,
             SqlCacheContext sqlCacheContext, UserIdentity currentUserIdentity) {
diff --git a/fe/fe-core/src/main/java/org/apache/doris/nereids/parser/NereidsParser.java b/fe/fe-core/src/main/java/org/apache/doris/nereids/parser/NereidsParser.java
index edcbb76ad842d0..203407d448e4ec 100644
--- a/fe/fe-core/src/main/java/org/apache/doris/nereids/parser/NereidsParser.java
+++ b/fe/fe-core/src/main/java/org/apache/doris/nereids/parser/NereidsParser.java
@@ -40,6 +40,7 @@
 import org.antlr.v4.runtime.CharStreams;
 import org.antlr.v4.runtime.CommonTokenStream;
 import org.antlr.v4.runtime.ParserRuleContext;
+import org.antlr.v4.runtime.Recognizer;
 import org.antlr.v4.runtime.Token;
 import org.antlr.v4.runtime.TokenSource;
 import org.antlr.v4.runtime.atn.PredictionMode;
@@ -334,4 +335,42 @@ public static ParserRuleContext toAst(String sql, Function<DorisParser, ParserRu
         }
         return tree;
     }
+
+    /**
+     * removeCommentAndTrimBlank
+     *
+     * for example: select   \/*+SET_VAR(key=value)*\/ \/* trace_id: 1234 *\/ *,   a, \n b from table
+     *
+     * will be normalized to: select \/*+SET_VAR(key=value)*\/ * , a, b from table
+     */
+    public static String removeCommentAndTrimBlank(String sql) {
+        DorisLexer lexer = new DorisLexer(new CaseInsensitiveStream(CharStreams.fromString(sql)));
+        CommonTokenStream tokenStream = new CommonTokenStream(lexer);
+        tokenStream.fill();
+
+        // maybe add more space char
+        StringBuilder newSql = new StringBuilder((int) (sql.length() * 1.2));
+
+        for (Token token : tokenStream.getTokens()) {
+            int tokenType = token.getType();
+            switch (tokenType) {
+                case DorisLexer.SIMPLE_COMMENT:
+                case DorisLexer.WS:
+                case Recognizer.EOF:
+                    break;
+                case DorisLexer.BRACKETED_COMMENT:
+                    String bracketedComment = token.getText();
+                    // append hint
+                    if (bracketedComment.startsWith("/*+")) {
+                        newSql.append(bracketedComment);
+                        newSql.append(" ");
+                    }
+                    break;
+                default:
+                    newSql.append(token.getText());
+                    newSql.append(" ");
+            }
+        }
+        return newSql.toString().trim();
+    }
 }
diff --git a/regression-test/framework/src/main/groovy/org/apache/doris/regression/util/LoggerUtils.groovy b/regression-test/framework/src/main/groovy/org/apache/doris/regression/util/LoggerUtils.groovy
index 2bc01e6f4ba70f..bcb04e8e9ea9fb 100644
--- a/regression-test/framework/src/main/groovy/org/apache/doris/regression/util/LoggerUtils.groovy
+++ b/regression-test/framework/src/main/groovy/org/apache/doris/regression/util/LoggerUtils.groovy
@@ -17,15 +17,15 @@
 
 package org.apache.doris.regression.util
 
+import com.google.common.collect.Sets
+
 class LoggerUtils {
     static Tuple2<Integer, String> getErrorInfo(Throwable t, File file) {
         if (file.name.endsWith(".groovy")) {
+            def st = findRootErrorStackTrace(t, Sets.newLinkedHashSet(), file)
             int lineNumber = -1
-            for (def st : t.getStackTrace()) {
-                if (Objects.equals(st.fileName, file.name)) {
-                    lineNumber = st.getLineNumber()
-                    break
-                }
+            if (!st.is(null)) {
+                lineNumber = st.getLineNumber()
             }
             if (lineNumber == -1) {
                 return new Tuple2<Integer, String>(null, null)
@@ -40,4 +40,23 @@ class LoggerUtils {
             return new Tuple2<Integer, String>(null, null)
         }
     }
+
+    static StackTraceElement findRootErrorStackTrace(Throwable t, Set<Throwable> throwables, File file) {
+        throwables.add(t)
+
+        def cause = t.getCause()
+        if (!cause.is(null) && !throwables.contains(cause)) {
+            def foundStackTrace = findRootErrorStackTrace(cause, throwables, file)
+            if (!foundStackTrace.is(null)) {
+                return foundStackTrace
+            }
+        }
+
+        for (def st : t.getStackTrace()) {
+            if (Objects.equals(st.fileName, file.name)) {
+                return st
+            }
+        }
+        return null
+    }
 }
diff --git a/regression-test/plugins/test_helper.groovy b/regression-test/plugins/test_helper.groovy
index 4f7eeb3c09b380..60fb9d2c8ed40f 100644
--- a/regression-test/plugins/test_helper.groovy
+++ b/regression-test/plugins/test_helper.groovy
@@ -57,6 +57,8 @@ Suite.metaClass.createTestTable = { String tableName, boolean uniqueTable = fals
                (4, 1), (4, 2),
                (5, 1), (5, 2)
         """
+
+    sql "sync"
 }
 
 
diff --git a/regression-test/suites/nereids_p0/cache/parse_sql_from_sql_cache.groovy b/regression-test/suites/nereids_p0/cache/parse_sql_from_sql_cache.groovy
index 2c17da24661a44..2c8660ab7c0f27 100644
--- a/regression-test/suites/nereids_p0/cache/parse_sql_from_sql_cache.groovy
+++ b/regression-test/suites/nereids_p0/cache/parse_sql_from_sql_cache.groovy
@@ -674,10 +674,7 @@ suite("parse_sql_from_sql_cache") {
             def result2 = sql "select * from (select $randomInt as id)a"
             assertTrue(result2.size() == 1)
 
-            assertNoCache "select * from test_use_plan_cache20 limit 0"
-            def result3 = sql "select * from test_use_plan_cache20 limit 0"
-            assertTrue(result3.isEmpty())
-
+            sql "select * from test_use_plan_cache20 limit 0"
             assertHasCache "select * from test_use_plan_cache20 limit 0"
             def result4 = sql "select * from test_use_plan_cache20 limit 0"
             assertTrue(result4.isEmpty())
@@ -723,6 +720,21 @@ suite("parse_sql_from_sql_cache") {
             assertNoCache "select * from test_use_plan_cache21"
             def result2 = sql "select * from test_use_plan_cache21"
             assertTrue(result2.size() == 1)
+        }),
+        extraThread("remove_comment", {
+            createTestTable "test_use_plan_cache22"
+
+            // after partition changed 10s, the sql cache can be used
+            sleep(10000)
+
+            sql "set enable_nereids_planner=true"
+            sql "set enable_fallback_to_original_planner=false"
+            sql "set enable_sql_cache=true"
+
+            assertNoCache "select /*+SET_VAR(disable_nereids_rules='')*/ /*comment2*/ * from test_use_plan_cache22 order by 1, 2"
+            sql "select /*+SET_VAR(disable_nereids_rules='')*/ /*comment1*/ * from test_use_plan_cache22 order by 1, 2"
+
+            assertHasCache "select /*+SET_VAR(disable_nereids_rules='')*/ /*comment2*/ * from test_use_plan_cache22 order by 1, 2"
         })
     ).get()
 }