diff --git a/CHANGELOG/CHANGELOG-1.6.md b/CHANGELOG/CHANGELOG-1.6.md
index 834d97f5a63..5ed64b8fad5 100644
--- a/CHANGELOG/CHANGELOG-1.6.md
+++ b/CHANGELOG/CHANGELOG-1.6.md
@@ -1,5 +1,22 @@
 # Changelog 1.6
 
+## 1.6.1 - 2022-05-11
+
+### Added
+
+- Add [documentation](https://github.com/antrea-io/antrea/blob/release-1.6/docs/security.md#protecting-your-cluster-against-privilege-escalations) for the Antrea Agent RBAC permissions and how to restrict them using Gatekeeper/OPA. ([#3694](https://github.com/antrea-io/antrea/pull/3694), [@antoninbas])
+
+### Fixed
+
+- Clean up stale routes installed by AntreaProxy when ProxyAll is disabled. ([#3465](https://github.com/antrea-io/antrea/pull/3465), [@hongliangl])
+- Fix export/import of Services with named ports when using the Antrea Multi-cluster feature. ([#3561](https://github.com/antrea-io/antrea/pull/3561), [@luolanzone])
+- Fix handling of the "reject" packets generated by the Antrea Agent to avoid infinite looping. ([#3569](https://github.com/antrea-io/antrea/pull/3569), [@GraysonWu])
+- Fix DNS resolution error of Antrea Agent on AKS by using `ClusterFirst` dnsPolicy. ([#3701](https://github.com/antrea-io/antrea/pull/3701), [@tnqn])
+- Fix tolerations for Pods running on control-plane for Kubernetes >= 1.24. ([#3731](https://github.com/antrea-io/antrea/pull/3731), [@xliuxu])
+- Reduce permissions of Antrea Agent ServiceAccount. ([#3691](https://github.com/antrea-io/antrea/pull/3691), [@xliuxu])
+- [Windows] Ensure that Service traffic does not bypass NetworkPolicies when ProxyAll is enabled. ([#3510](https://github.com/antrea-io/antrea/pull/3510), [@hongliangl])
+- Fix Antrea wildcard FQDN NetworkPolicies not working when NodeLocal DNSCache is enabled. ([#3510](https://github.com/antrea-io/antrea/pull/3510), [@hongliangl])
+
 ## 1.6.0 - 2022-03-29
 
 - The Egress feature is graduated from Alpha to Beta and is therefore enabled by default.