diff --git a/package-lock.json b/package-lock.json
index 6849e395790b6..040fe3911f377 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -28177,9 +28177,9 @@
 			}
 		},
 		"caniuse-lite": {
-			"version": "1.0.30001434",
-			"resolved": "https://registry.npmjs.org/caniuse-lite/-/caniuse-lite-1.0.30001434.tgz",
-			"integrity": "sha512-aOBHrLmTQw//WFa2rcF1If9fa3ypkC1wzqqiKHgfdrXTWcU8C4gKVZT77eQAPWN1APys3+uQ0Df07rKauXGEYA=="
+			"version": "1.0.30001488",
+			"resolved": "https://registry.npmjs.org/caniuse-lite/-/caniuse-lite-1.0.30001488.tgz",
+			"integrity": "sha512-NORIQuuL4xGpIy6iCCQGN4iFjlBXtfKWIenlUuyZJumLRIindLb7wXM+GO8erEhb7vXfcnf4BAg2PrSDN5TNLQ=="
 		},
 		"capital-case": {
 			"version": "1.0.4",
diff --git a/packages/block-editor/src/components/publish-date-time-picker/index.js b/packages/block-editor/src/components/publish-date-time-picker/index.js
index 364fb09594802..418006cf854c1 100644
--- a/packages/block-editor/src/components/publish-date-time-picker/index.js
+++ b/packages/block-editor/src/components/publish-date-time-picker/index.js
@@ -29,8 +29,6 @@ function PublishDateTimePicker(
 			/>
 			<DateTimePicker
 				startOfWeek={ getSettings().l10n.startOfWeek }
-				__nextRemoveHelpButton
-				__nextRemoveResetButton
 				onChange={ onChange }
 				{ ...additionalProps }
 			/>
diff --git a/packages/components/CHANGELOG.md b/packages/components/CHANGELOG.md
index d4cc445dd379d..6c00d6e22027b 100644
--- a/packages/components/CHANGELOG.md
+++ b/packages/components/CHANGELOG.md
@@ -2,6 +2,10 @@
 
 ## Unreleased
 
+### Breaking Changes
+
+-   `DateTime`: Remove previously deprecated props, `__nextRemoveHelpButton` and `__nextRemoveResetButton` ([#50724](https://github.com/WordPress/gutenberg/pull/50724)).
+
 ### Internal
 
 -   `Modal`: Remove children container's unused class name ([#50655](https://github.com/WordPress/gutenberg/pull/50655)).
diff --git a/packages/components/src/date-time/README.md b/packages/components/src/date-time/README.md
index e01d9074953f2..c65cf6d3a1aae 100644
--- a/packages/components/src/date-time/README.md
+++ b/packages/components/src/date-time/README.md
@@ -26,8 +26,6 @@ const MyDateTimePicker = () => {
 			currentDate={ date }
 			onChange={ ( newDate ) => setDate( newDate ) }
 			is12Hour={ true }
-			__nextRemoveHelpButton
-			__nextRemoveResetButton
 		/>
 	);
 };
@@ -83,17 +81,3 @@ The day that the week should start on. 0 for Sunday, 1 for Monday, etc.
 
 - Required: No
 - Default: 0
-
-### `__nextRemoveHelpButton`: `boolean`
-
-Start opting in to not displaying a Help button which will become the default in a future version.
-
-- Required: No
-- Default: `false`
-
-### `__nextRemoveResetButton`: `boolean`
-
-Start opting in to not displaying a Reset button which will become the default in a future version.
-
-- Required: No
-- Default: `false`
diff --git a/packages/components/src/date-time/date-time/index.tsx b/packages/components/src/date-time/date-time/index.tsx
index 123f20e76c640..a75b9fe57c14e 100644
--- a/packages/components/src/date-time/date-time/index.tsx
+++ b/packages/components/src/date-time/date-time/index.tsx
@@ -6,21 +6,16 @@ import type { ForwardedRef } from 'react';
 /**
  * WordPress dependencies
  */
-import { useState, forwardRef } from '@wordpress/element';
+import { forwardRef } from '@wordpress/element';
 import { __, _x } from '@wordpress/i18n';
-import deprecated from '@wordpress/deprecated';
 
 /**
  * Internal dependencies
  */
-import Button from '../../button';
 import { default as DatePicker } from '../date';
 import { default as TimePicker } from '../time';
 import type { DateTimePickerProps } from '../types';
-import { Wrapper, CalendarHelp } from './styles';
-import { HStack } from '../../h-stack';
-import { Heading } from '../../heading';
-import { Spacer } from '../../spacer';
+import { Wrapper } from './styles';
 
 export { DatePicker, TimePicker };
 
@@ -35,157 +30,26 @@ function UnforwardedDateTimePicker(
 		onChange,
 		events,
 		startOfWeek,
-		__nextRemoveHelpButton = false,
-		__nextRemoveResetButton = false,
 	}: DateTimePickerProps,
 	ref: ForwardedRef< any >
 ) {
-	if ( ! __nextRemoveHelpButton ) {
-		deprecated( 'Help button in wp.components.DateTimePicker', {
-			since: '13.4',
-			version: '15.8', // One year of plugin releases.
-			hint: 'Set the `__nextRemoveHelpButton` prop to `true` to remove this warning and opt in to the new behaviour, which will become the default in a future version.',
-		} );
-	}
-	if ( ! __nextRemoveResetButton ) {
-		deprecated( 'Reset button in wp.components.DateTimePicker', {
-			since: '13.4',
-			version: '15.8', // One year of plugin releases.
-			hint: 'Set the `__nextRemoveResetButton` prop to `true` to remove this warning and opt in to the new behaviour, which will become the default in a future version.',
-		} );
-	}
-
-	const [ calendarHelpIsVisible, setCalendarHelpIsVisible ] =
-		useState( false );
-
-	function onClickDescriptionToggle() {
-		setCalendarHelpIsVisible( ! calendarHelpIsVisible );
-	}
-
 	return (
 		<Wrapper ref={ ref } className="components-datetime" spacing={ 4 }>
-			{ ! calendarHelpIsVisible && (
-				<>
-					<TimePicker
-						currentTime={ currentDate }
-						onChange={ onChange }
-						is12Hour={ is12Hour }
-					/>
-					<DatePicker
-						currentDate={ currentDate }
-						onChange={ onChange }
-						isInvalidDate={ isInvalidDate }
-						events={ events }
-						onMonthPreviewed={ onMonthPreviewed }
-						startOfWeek={ startOfWeek }
-					/>
-				</>
-			) }
-			{ calendarHelpIsVisible && (
-				<CalendarHelp
-					className="components-datetime__calendar-help" // Unused, for backwards compatibility.
-				>
-					<Heading level={ 4 }>{ __( 'Click to Select' ) }</Heading>
-					<ul>
-						<li>
-							{ __(
-								'Click the right or left arrows to select other months in the past or the future.'
-							) }
-						</li>
-						<li>{ __( 'Click the desired day to select it.' ) }</li>
-					</ul>
-					<Heading level={ 4 }>
-						{ __( 'Navigating with a keyboard' ) }
-					</Heading>
-					<ul>
-						<li>
-							<abbr
-								aria-label={ _x( 'Enter', 'keyboard button' ) }
-							>
-								↵
-							</abbr>
-							{
-								' ' /* JSX removes whitespace, but a space is required for screen readers. */
-							}
-							<span>{ __( 'Select the date in focus.' ) }</span>
-						</li>
-						<li>
-							<abbr aria-label={ __( 'Left and Right Arrows' ) }>
-								←/→
-							</abbr>
-							{
-								' ' /* JSX removes whitespace, but a space is required for screen readers. */
-							}
-							{ __(
-								'Move backward (left) or forward (right) by one day.'
-							) }
-						</li>
-						<li>
-							<abbr aria-label={ __( 'Up and Down Arrows' ) }>
-								↑/↓
-							</abbr>
-							{
-								' ' /* JSX removes whitespace, but a space is required for screen readers. */
-							}
-							{ __(
-								'Move backward (up) or forward (down) by one week.'
-							) }
-						</li>
-						<li>
-							<abbr aria-label={ __( 'Page Up and Page Down' ) }>
-								{ __( 'PgUp/PgDn' ) }
-							</abbr>
-							{
-								' ' /* JSX removes whitespace, but a space is required for screen readers. */
-							}
-							{ __(
-								'Move backward (PgUp) or forward (PgDn) by one month.'
-							) }
-						</li>
-						<li>
-							<abbr aria-label={ __( 'Home and End' ) }>
-								{ /* Translators: Home/End reffer to the 'Home' and 'End' buttons on the keyboard.*/ }
-								{ __( 'Home/End' ) }
-							</abbr>
-							{
-								' ' /* JSX removes whitespace, but a space is required for screen readers. */
-							}
-							{ __(
-								'Go to the first (Home) or last (End) day of a week.'
-							) }
-						</li>
-					</ul>
-				</CalendarHelp>
-			) }
-			{ ( ! __nextRemoveResetButton || ! __nextRemoveHelpButton ) && (
-				<HStack
-					className="components-datetime__buttons" // Unused, for backwards compatibility.
-				>
-					{ ! __nextRemoveResetButton &&
-						! calendarHelpIsVisible &&
-						currentDate && (
-							<Button
-								className="components-datetime__date-reset-button" // Unused, for backwards compatibility.
-								variant="link"
-								onClick={ () => onChange?.( null ) }
-							>
-								{ __( 'Reset' ) }
-							</Button>
-						) }
-					<Spacer />
-					{ ! __nextRemoveHelpButton && (
-						<Button
-							className="components-datetime__date-help-toggle" // Unused, for backwards compatibility.
-							variant="link"
-							onClick={ onClickDescriptionToggle }
-						>
-							{ calendarHelpIsVisible
-								? __( 'Close' )
-								: __( 'Calendar Help' ) }
-						</Button>
-					) }
-				</HStack>
-			) }
+			<>
+				<TimePicker
+					currentTime={ currentDate }
+					onChange={ onChange }
+					is12Hour={ is12Hour }
+				/>
+				<DatePicker
+					currentDate={ currentDate }
+					onChange={ onChange }
+					isInvalidDate={ isInvalidDate }
+					events={ events }
+					onMonthPreviewed={ onMonthPreviewed }
+					startOfWeek={ startOfWeek }
+				/>
+			</>
 		</Wrapper>
 	);
 }
@@ -207,8 +71,6 @@ function UnforwardedDateTimePicker(
  *       currentDate={ date }
  *       onChange={ ( newDate ) => setDate( newDate ) }
  *       is12Hour
- *       __nextRemoveHelpButton
- *       __nextRemoveResetButton
  *     />
  *   );
  * };
diff --git a/packages/components/src/date-time/date-time/styles.ts b/packages/components/src/date-time/date-time/styles.ts
index a7f23eb276e04..51dc6e71f0c46 100644
--- a/packages/components/src/date-time/date-time/styles.ts
+++ b/packages/components/src/date-time/date-time/styles.ts
@@ -11,7 +11,3 @@ import { VStack } from '../../v-stack';
 export const Wrapper = styled( VStack )`
 	box-sizing: border-box;
 `;
-
-export const CalendarHelp = styled.div`
-	min-width: 260px;
-`;
diff --git a/packages/components/src/date-time/stories/date-time.tsx b/packages/components/src/date-time/stories/date-time.tsx
index 53d369728d34d..447b9cf265ab8 100644
--- a/packages/components/src/date-time/stories/date-time.tsx
+++ b/packages/components/src/date-time/stories/date-time.tsx
@@ -52,10 +52,6 @@ const Template: ComponentStory< typeof DateTimePicker > = ( {
 export const Default: ComponentStory< typeof DateTimePicker > = Template.bind(
 	{}
 );
-Default.args = {
-	__nextRemoveHelpButton: true,
-	__nextRemoveResetButton: true,
-};
 
 export const WithEvents: ComponentStory< typeof DateTimePicker > =
 	Template.bind( {} );
diff --git a/packages/components/src/date-time/types.ts b/packages/components/src/date-time/types.ts
index ae99a7082dcd2..02df096a866b9 100644
--- a/packages/components/src/date-time/types.ts
+++ b/packages/components/src/date-time/types.ts
@@ -73,20 +73,4 @@ export type DateTimePickerProps = Omit< DatePickerProps, 'onChange' > &
 		 * passed the date and time as an argument.
 		 */
 		onChange?: ( date: string | null ) => void;
-
-		/**
-		 * Start opting in to not displaying a Help button which will become the
-		 * default in a future version.
-		 *
-		 * @default false
-		 */
-		__nextRemoveHelpButton?: boolean;
-
-		/**
-		 * Start opting in to not displaying a Reset button which will become
-		 * the default in a future version.
-		 *
-		 * @default false
-		 */
-		__nextRemoveResetButton?: boolean;
 	};
diff --git a/packages/dependency-extraction-webpack-plugin/test/__snapshots__/build.js.snap b/packages/dependency-extraction-webpack-plugin/test/__snapshots__/build.js.snap
index f5bf010b1ef8d..42102ca2cb132 100644
--- a/packages/dependency-extraction-webpack-plugin/test/__snapshots__/build.js.snap
+++ b/packages/dependency-extraction-webpack-plugin/test/__snapshots__/build.js.snap
@@ -1,7 +1,7 @@
 // Jest Snapshot v1, https://goo.gl/fbAQLP
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`combine-assets\` should produce expected output: Asset file 'assets.php' should match snapshot 1`] = `
-"<?php return array('fileA.js' => array('dependencies' => array('lodash', 'wp-blob'), 'version' => 'bf200ecb3dcb6881a1f3'), 'fileB.js' => array('dependencies' => array('wp-token-list'), 'version' => '0af6c51a8e6ac934b85a'));
+"<?php return array('fileA.js' => array('dependencies' => array('lodash', 'wp-blob'), 'version' => 'cf268e19006bef774112'), 'fileB.js' => array('dependencies' => array('wp-token-list'), 'version' => '7f3970305cf0aecb54ab'));
 "
 `;
 
@@ -32,7 +32,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`combine-assets\` should pro
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`dynamic-import\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('wp-blob'), 'version' => '782d84ec5d7303bb6bd2');
+"<?php return array('dependencies' => array('wp-blob'), 'version' => 'c8be4fceac30d1d00ca7');
 "
 `;
 
@@ -50,7 +50,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`dynamic-import\` should pro
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`function-output-filename\` should produce expected output: Asset file 'chunk--main--main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '4c78134607e6ed966df3');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '9b7ebe61044661fdabda');
 "
 `;
 
@@ -73,7 +73,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`function-output-filename\`
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`has-extension-suffix\` should produce expected output: Asset file 'index.min.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => 'dabeb91f3cb9dd73d48d');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '49dba68ef238f954b358');
 "
 `;
 
@@ -96,21 +96,21 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`has-extension-suffix\` shou
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`no-default\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array(), 'version' => 'bb85a9737103c7054b00');
+"<?php return array('dependencies' => array(), 'version' => 'f7e2cb527e601f74f8bd');
 "
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`no-default\` should produce expected output: External modules should match snapshot 1`] = `[]`;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`no-deps\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array(), 'version' => '091ffcd70d94dd16e773');
+"<?php return array('dependencies' => array(), 'version' => '143ed23d4b8be5611fcb');
 "
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`no-deps\` should produce expected output: External modules should match snapshot 1`] = `[]`;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`option-function-output-filename\` should produce expected output: Asset file 'chunk--main--main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '4c78134607e6ed966df3');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '9b7ebe61044661fdabda');
 "
 `;
 
@@ -133,7 +133,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`option-function-output-file
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`option-output-filename\` should produce expected output: Asset file 'main-foo.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '4c78134607e6ed966df3');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '9b7ebe61044661fdabda');
 "
 `;
 
@@ -155,7 +155,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`option-output-filename\` sh
 ]
 `;
 
-exports[`DependencyExtractionWebpackPlugin Webpack \`output-format-json\` should produce expected output: Asset file 'main.asset.json' should match snapshot 1`] = `"{"dependencies":["lodash"],"version":"a8f35bfc9f46482cc48a"}"`;
+exports[`DependencyExtractionWebpackPlugin Webpack \`output-format-json\` should produce expected output: Asset file 'main.asset.json' should match snapshot 1`] = `"{"dependencies":["lodash"],"version":"4c42b9646049ad2e9438"}"`;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`output-format-json\` should produce expected output: External modules should match snapshot 1`] = `
 [
@@ -168,7 +168,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`output-format-json\` should
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`overrides\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('wp-blob', 'wp-script-handle-for-rxjs', 'wp-url'), 'version' => '2a29b245fc3d0509b5a8');
+"<?php return array('dependencies' => array('wp-blob', 'wp-script-handle-for-rxjs', 'wp-url'), 'version' => '708c71445153f1d07e4a');
 "
 `;
 
@@ -207,17 +207,17 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`overrides\` should produce
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`runtime-chunk-single\` should produce expected output: Asset file 'a.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('wp-blob'), 'version' => '4514ed711f6c035e0887');
+"<?php return array('dependencies' => array('wp-blob'), 'version' => '09a0c551770a351c5ca7');
 "
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`runtime-chunk-single\` should produce expected output: Asset file 'b.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '168d32b5fb42f9e5d8ce');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => 'c9f00d690a9f72438910');
 "
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`runtime-chunk-single\` should produce expected output: Asset file 'runtime.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array(), 'version' => 'd3c2ce2cb84ff74b92e0');
+"<?php return array('dependencies' => array(), 'version' => '46ea0ff11ac53fa5e88b');
 "
 `;
 
@@ -240,7 +240,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`runtime-chunk-single\` shou
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`style-imports\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '04b9da7eff6fbfcb0452');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => 'd8c0ee89d933a3809c0e');
 "
 `;
 
@@ -263,7 +263,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`style-imports\` should prod
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`wordpress\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '4c78134607e6ed966df3');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '9b7ebe61044661fdabda');
 "
 `;
 
@@ -286,7 +286,7 @@ exports[`DependencyExtractionWebpackPlugin Webpack \`wordpress\` should produce
 `;
 
 exports[`DependencyExtractionWebpackPlugin Webpack \`wordpress-require\` should produce expected output: Asset file 'main.asset.php' should match snapshot 1`] = `
-"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => 'ed2bd4e7df46768bb3c2');
+"<?php return array('dependencies' => array('lodash', 'wp-blob'), 'version' => '40370eb4ce6428562da6');
 "
 `;
 
diff --git a/packages/readable-js-assets-webpack-plugin/test/__snapshots__/build.js.snap b/packages/readable-js-assets-webpack-plugin/test/__snapshots__/build.js.snap
index e5a7d6f6accc8..c033e572e8e5e 100644
--- a/packages/readable-js-assets-webpack-plugin/test/__snapshots__/build.js.snap
+++ b/packages/readable-js-assets-webpack-plugin/test/__snapshots__/build.js.snap
@@ -1,7 +1,7 @@
 // Jest Snapshot v1, https://goo.gl/fbAQLP
 
 exports[`ReadableJsAssetsWebpackPlugin should produce the expected output: Asset file index.js should match snapshot 1`] = `
-"/******/ (function() { // webpackBootstrap
+"/******/ (() => { // webpackBootstrap
 var __webpack_exports__ = {};
 function notMinified() {
 	// eslint-disable-next-line no-console
@@ -16,7 +16,7 @@ notMinified();
 exports[`ReadableJsAssetsWebpackPlugin should produce the expected output: Asset file index.min.js should match snapshot 1`] = `"console.log("hello");"`;
 
 exports[`ReadableJsAssetsWebpackPlugin should produce the expected output: Asset file view.js should match snapshot 1`] = `
-"/******/ (function() { // webpackBootstrap
+"/******/ (() => { // webpackBootstrap
 var __webpack_exports__ = {};
 function notMinified() {
 	// eslint-disable-next-line no-console