diff --git a/packages/opentelemetry-core/src/trace/instrumentation/BasePlugin.ts b/packages/opentelemetry-core/src/trace/instrumentation/BasePlugin.ts
index 90631c7830b..b50f739481e 100644
--- a/packages/opentelemetry-core/src/trace/instrumentation/BasePlugin.ts
+++ b/packages/opentelemetry-core/src/trace/instrumentation/BasePlugin.ts
@@ -21,6 +21,7 @@ export abstract class BasePlugin<T> implements Plugin<T> {
   protected _moduleExports!: T;
   protected _tracer!: Tracer;
   protected _logger!: Logger;
+  supportedVersions?: string[];
 
   enable(
     moduleExports: T,
diff --git a/packages/opentelemetry-node-tracer/src/instrumentation/PluginLoader.ts b/packages/opentelemetry-node-tracer/src/instrumentation/PluginLoader.ts
index 7137983bfae..20a680a097e 100644
--- a/packages/opentelemetry-node-tracer/src/instrumentation/PluginLoader.ts
+++ b/packages/opentelemetry-node-tracer/src/instrumentation/PluginLoader.ts
@@ -90,8 +90,6 @@ export class PluginLoader {
           `PluginLoader#load: trying loading ${name}.${version}`
         );
 
-        // @todo (issues/132): Check if version and supportedVersions are
-        // satisfied
         if (!version) return exports;
 
         this.logger.debug(
@@ -101,6 +99,11 @@ export class PluginLoader {
         // Expecting a plugin from module;
         try {
           const plugin: Plugin = require(moduleName).plugin;
+
+          if (!utils.isSupportedVersion(version, plugin.supportedVersions)) {
+            return exports;
+          }
+
           this._plugins.push(plugin);
           // Enable each supported plugin.
           return plugin.enable(exports, this.tracer, this.logger);
diff --git a/packages/opentelemetry-node-tracer/src/instrumentation/utils.ts b/packages/opentelemetry-node-tracer/src/instrumentation/utils.ts
index de9648e3024..1ea90230142 100644
--- a/packages/opentelemetry-node-tracer/src/instrumentation/utils.ts
+++ b/packages/opentelemetry-node-tracer/src/instrumentation/utils.ts
@@ -60,6 +60,19 @@ export function getPackageVersion(
   }
 }
 
+export function isSupportedVersion(
+  moduleVersion: string,
+  supportedVersions?: string[]
+) {
+  if (!Array.isArray(supportedVersions)) {
+    return true;
+  }
+
+  return supportedVersions.some(supportedVersion =>
+    semver.satisfies(moduleVersion, supportedVersion)
+  );
+}
+
 /**
  * Adds a search path for plugin modules. Intended for testing purposes only.
  * @param searchPath The path to add.
diff --git a/packages/opentelemetry-node-tracer/test/instrumentation/utils.test.ts b/packages/opentelemetry-node-tracer/test/instrumentation/utils.test.ts
index 66d25390c59..c90bb469c90 100644
--- a/packages/opentelemetry-node-tracer/test/instrumentation/utils.test.ts
+++ b/packages/opentelemetry-node-tracer/test/instrumentation/utils.test.ts
@@ -69,4 +69,45 @@ describe('Instrumentation#utils', () => {
       });
     });
   });
+  describe('isSupportedVersion', () => {
+    const version = '1.0.1';
+
+    it('should return true when supportedVersions is not defined', () => {
+      assert.strictEqual(utils.isSupportedVersion('1.0.0', undefined), true);
+    });
+
+    [
+      ['1.X'],
+      [version],
+      ['1.X.X', '3.X.X'],
+      ['^1.0.0'],
+      ['~1.0.0', '^0.1.0'],
+      ['*'],
+      ['>1.0.0'],
+    ].forEach(supportedVersion => {
+      it(`should return true when version is equal to ${version} and supportedVersions is equal to ${supportedVersion}`, () => {
+        assert.strictEqual(
+          utils.isSupportedVersion(version, supportedVersion),
+          true
+        );
+      });
+    });
+
+    [['0.X'], ['0.0.1'], ['0.X.X'], ['^0.1.0'], ['1.0.0'], ['<1.0.0']].forEach(
+      supportedVersion => {
+        it(`should return false when version is equal to ${version} and supportedVersions is equal to ${supportedVersion}`, () => {
+          assert.strictEqual(
+            utils.isSupportedVersion(version, supportedVersion),
+            false
+          );
+        });
+      }
+    );
+
+    it(`should return false when version is equal to null and supportedVersions is equal to '*'`, () => {
+      /* tslint:disable:no-any */
+      assert.strictEqual(utils.isSupportedVersion(null as any, ['*']), false);
+      /* tslint:enable:no-any */
+    });
+  });
 });
diff --git a/packages/opentelemetry-types/src/trace/instrumentation/Plugin.ts b/packages/opentelemetry-types/src/trace/instrumentation/Plugin.ts
index 643a4d45291..0c1174d963e 100644
--- a/packages/opentelemetry-types/src/trace/instrumentation/Plugin.ts
+++ b/packages/opentelemetry-types/src/trace/instrumentation/Plugin.ts
@@ -20,6 +20,14 @@ import { Logger } from '../../common/Logger';
 /** Interface Plugin to apply patch. */
 // tslint:disable-next-line:no-any
 export interface Plugin<T = any> {
+  /**
+   * Contains all supported versions.
+   * all versions must be compatible with [semver](https://semver.org/spec/v2.0.0.html) format.
+   * If the version is not supported, we won't apply instrumentation patch (see `enable` method).
+   * If not defined, we will apply instrumentation for every version.
+   */
+  supportedVersions?: string[];
+
   /**
    * Method that enables the instrumentation patch.
    * @param moduleExports The value of the `module.exports` property that would