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More Duplicate Beta-Oxidation Reactions for Linoleoyl- and gamma-Linolenoyl-CoA #763

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Devlin-Moyer opened this issue Dec 11, 2023 · 0 comments
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@Devlin-Moyer
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Devlin-Moyer commented Dec 11, 2023

Current behavior:

In addition to the duplicate pathways mentioned in #761, there are also two reactions that convert linoleoyl-CoA and γ-linolenoyl-CoA directly into octanoyl-CoA, which are redundant with all of the reactions mentioned in #761 and the 6 other reactions that convert 4-cis-decenoyl-CoA to octanoyl-CoA:

linoleoyl-CoA to octanoyl-CoA: MAR00785 or MAR03275 + MAR03277 + MAR03278 + MAR03279 + MAR03280 + MAR03281 + MAR03282 + MAR03283 + MAR03284 + MAR03285 + MAR03286 + MAR03287 + MAR03288 + MAR03290 + MAR03292 + MAR03293 + MAR03294 + MAR04970 + MAR03298 + MAR03143 + MAR03144 + MAR03146

γ-linolenoyl-CoA to octanoyl-CoA: MAR00799 or MAR03452 + MAR03453 + MAR03454 + MAR03455 + MAR03456+ MAR03457 + MAR03458 + MAR03281 + MAR03282 + MAR03283 + MAR03284 + MAR03285 + MAR03286 + MAR03287 + MAR03288 + MAR03290 + MAR03292 + MAR03293 + MAR03294 + MAR04970 + MAR03298 + MAR03143 + MAR03144 + MAR03146

Proposed changes:

  • Remove MAR00785 for being a duplicate of MAR03275 + MAR03277 + MAR03278 + MAR03279 + MAR03280 + MAR03281 + MAR03282 + MAR03283 + MAR03284 + MAR03285 + MAR03286 + MAR03287 + MAR03288 + MAR03290 + MAR03292 + MAR03293 + MAR03294 + MAR04970 + MAR03298 + MAR03143 + MAR03144 + MAR03146
  • Remove MAR00799 for being a duplicate of MAR03452 + MAR03453 + MAR03454 + MAR03455 + MAR03456+ MAR03457 + MAR03458 + MAR03281 + MAR03282 + MAR03283 + MAR03284 + MAR03285 + MAR03286 + MAR03287 + MAR03288 + MAR03290 + MAR03292 + MAR03293 + MAR03294 + MAR04970 + MAR03298 + MAR03143 + MAR03144 + MAR03146
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