diff --git a/workflow/Snakefile b/workflow/Snakefile
index 29164fe..c954718 100644
--- a/workflow/Snakefile
+++ b/workflow/Snakefile
@@ -85,7 +85,6 @@ if assay == "cfchip":
         join(cfTool_dir, "Output", "H3K4me3", "Signatures", "{name}.Q5DD.csv"), 
         name=chips
     ))
-
     if has_inputs:
         rule_all_ins.append(
             join(qc_dir, "AllSamples-macsNarrow", "AllSamples-macsNarrow_DiffBindQC_TMMcounts.bed")
diff --git a/workflow/rules/dba.smk b/workflow/rules/dba.smk
index 7958029..26f244d 100644
--- a/workflow/rules/dba.smk
+++ b/workflow/rules/dba.smk
@@ -44,7 +44,7 @@ if reps == "yes": otherDirs.append(diffbind_dir)
 mk_dir_if_not_exist(PeakTools + otherDirs)
 
 
-localrules: diffbind_csv_macsN, diffbind_csv_macsB
+localrules: diffbind_csv_macsN, diffbind_csv_macsB, diffbind_csv_genrich
 
 
 # ~~ differential binding analysis ~~ #
@@ -117,6 +117,40 @@ rule diffbind_csv_macsN:
             ))
 
 
+rule diffbind_csv_genrich:
+    input:
+        bed                            = expand(join(genrich_dir, "{name}", "{name}.narrowPeak"), name=chips)
+    output:
+        csvfile                         = join(
+                                            diffbind_dir,
+                                            "{group1}_vs_{group2}-Genrich",
+                                            "{group1}_vs_{group2}-Genrich_Diffbind_prep.csv",
+                                          ),
+    params:
+        rname                           = "diffbind_csv_genrich",
+        this_peaktool                   = "Genrich",
+        peakcaller                      = "narrowPeak",
+        this_peakextension              = "_peaks.narrowPeak",
+        pythonscript                    = join(bin_path, "prep_diffbind.py"),
+        bam_dir                         = bam_dir,
+        workpath                        = workpath,
+    log: join(local_log_dir, "diffbind_csv_genrich", "{group1}_vs_{group2}_diffbind_csv.log")
+    run:
+        for i, contrast in enumerate(group_combos):
+            shell(dedent(
+                """
+                python {params.pythonscript} \\
+                    --con \"""" + contrast + """\" \\
+                    --wp {params.workpath} \\
+                    --pt {params.this_peaktool} \\
+                    --pe {params.this_peakextension} \\
+                    --bd {params.bam_dir} \\
+                    --pc {params.peakcaller} \\
+                    --csv {output.csvfile}
+                """
+            ))
+
+
 rule diffbind_csv_macsB:
     input:
         beds                            = expand(join(macsB_dir, "{name}", "{name}_peaks.broadPeak"), name=chips),
diff --git a/workflow/rules/qc.smk b/workflow/rules/qc.smk
index ad003de..317c8af 100644
--- a/workflow/rules/qc.smk
+++ b/workflow/rules/qc.smk
@@ -426,6 +426,37 @@ rule FRiP_macsN:
         """
 
 
+rule FRiP_Genrich:
+    input:
+        bed                     = expand(join(genrich_dir, "{name}", "{name}.narrowPeak"), name=chips),
+        bam                     = join(bam_dir, "{name}.Q5DD.bam"),
+    output:
+        join(workpath, "PeakQC", "Genrich.{name}.Q5DD.FRiP_table.txt"),
+    params:
+        rname                   = "FRiP_macsN",
+        outroot                 = join(peakqc_dir, "macsNarrow"),
+        script                  = join(bin_path, "frip.py"),
+        genome                  = config['references'][genome]['REFLEN'],
+        tmpdir                  = tmpdir,
+    container: 
+        config['images']['python']
+    shell: 
+        """
+        # Setups temporary directory for
+        # intermediate files with built-in 
+        # mechanism for deletion on exit
+        if [ ! -d "{params.tmpdir}" ]; then mkdir -p "{params.tmpdir}"; fi
+        tmp=$(mktemp -d -p "{params.tmpdir}")
+        trap 'rm -rf "${{tmp}}"' EXIT
+
+        python {params.script} \\
+            -p {input.bed} \\
+            -b {input.bam} \\
+            -g {params.genome} \\
+            -o {params.outroot}
+        """
+
+
 rule FRiP_macsB:
     input:
         bed                     = expand(join(macsB_dir, "{name}", "{name}_peaks.broadPeak"), name=chips),