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cob-native.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/cob/cob-native.owl#"
xml:base="http://purl.obolibrary.org/obo/cob/cob-native.owl"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:skos="http://www.w3.org/2004/02/skos/core#"
xmlns:terms="http://purl.org/dc/terms/">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/cob/cob-native.owl">
<owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/cob/releases/2024-09-20/cob-native.owl"/>
<terms:description xml:lang="en">COB brings together key terms from a wide range of OBO projects to improve interoperability.</terms:description>
<terms:license rdf:resource="https://creativecommons.org/publicdomain/zero/1.0/"/>
<terms:title xml:lang="en">Core Ontology for Biology and Biomedicine</terms:title>
<owl:versionInfo>2024-09-20</owl:versionInfo>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
<rdfs:label>definition</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000116 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000116"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000117 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
<!-- http://purl.org/dc/elements/1.1/date -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
<!-- http://purl.org/dc/elements/1.1/description -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
<!-- http://purl.org/dc/elements/1.1/title -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/title"/>
<!-- http://purl.org/dc/terms/date -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/date"/>
<!-- http://purl.org/dc/terms/description -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/description"/>
<!-- http://purl.org/dc/terms/license -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/license"/>
<!-- http://purl.org/dc/terms/title -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/title"/>
<!-- http://www.w3.org/2004/02/skos/core#exactMatch -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/COB_0000002 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000002">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000078"/>
<rdfs:label xml:lang="en">is concretized as</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000016 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000016">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000086"/>
<rdfs:label xml:lang="en">executed by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000023 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000023">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000512"/>
<rdfs:label xml:lang="en">characteristic of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000024 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000024">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000070"/>
<rdfs:label xml:lang="en">participates in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000027 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000027">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000024"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000039"/>
<rdfs:label xml:lang="en">is specified input of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000028 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000028">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000024"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000040"/>
<rdfs:label xml:lang="en">is specified output of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000029 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000029">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000087"/>
<rdfs:label xml:lang="en">realized in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000036 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000036">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000071"/>
<rdfs:label xml:lang="en">contains process</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000039 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000039">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000070"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000035"/>
<rdfs:label xml:lang="en">has specified input</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000040 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000040">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000070"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000035"/>
<rdfs:label xml:lang="en">has specified output</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000047 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000047">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000072"/>
<rdfs:label>has part</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000070 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000070">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<rdfs:label>has participant</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000071 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000071">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<rdfs:label>occurs in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000072 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000072">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:label>part of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000074 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000074">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000070"/>
<rdfs:label>enabled by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000078 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000078">
<rdfs:label>concretizes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000081 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000081">
<rdfs:label>intended to realize</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000084 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000084">
<rdfs:label>has plan</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000085 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000085">
<rdfs:label>intended plan process type</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000086 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000086">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/COB_0000087"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/COB_0000078"/>
</owl:propertyChainAxiom>
<rdfs:label>executes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000087 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000087">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/COB_0000033"/>
<rdfs:label>realizes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000512 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000512">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
<rdfs:domain rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/COB_0000502"/>
<rdfs:label>has characteristic</rdfs:label>
<rdfs:seeAlso>https://github.com/oborel/obo-relations/pull/284</rdfs:seeAlso>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/COB_0000512"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#domain"/>
<owl:annotatedTarget rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<obo:IAO_0000116>Anything can have a characteristic</obo:IAO_0000116>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/COB_0000513 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000513">
<rdfs:label>is about</rdfs:label>
</owl:ObjectProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Data properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/COB_0000511 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000511">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000502"/>
<obo:IAO_0000116>The range of this property should be a user-defined unit datatype, e.g 182^:cm</obo:IAO_0000116>
<rdfs:label>has quantity</rdfs:label>
<rdfs:seeAlso>https://github.com/OBOFoundry/COB/issues/35</rdfs:seeAlso>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000800 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000800">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000011"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
<obo:IAO_0000115>Number of protons in an atomic nucleus</obo:IAO_0000115>
<obo:IAO_0000116>We are undecided as to whether to ultimately model this as a data property of object property + cardinality, but for now we are using DPs as these are faster for reasoning</obo:IAO_0000116>
<rdfs:label xml:lang="en">has atomic number</rdfs:label>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000801 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000801">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
<rdfs:label xml:lang="en">has number of atomic nuclei</rdfs:label>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/COB_0000803 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/COB_0000803">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topDataProperty"/>
<rdfs:label xml:lang="en">has inchi string</rdfs:label>
</owl:DatatypeProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/COB_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000502"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000023"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">mass</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000502"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000023"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">charge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000005">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<obo:IAO_0000116>no longer needed</obo:IAO_0000116>
<rdfs:label xml:lang="en">obsolete_elementary charge</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000006">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label xml:lang="en">material entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:label xml:lang="en">subatomic particle</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000007"/>
<rdfs:label xml:lang="en">proton</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000007"/>
<rdfs:label xml:lang="en">neutron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000801"/>
<owl:hasValue rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">electron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000011">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000801"/>
<owl:hasValue rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</owl:hasValue>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000012"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000013"/>
<obo:IAO_0000115>A material entity consisting of exactly one atomic nucleus and the electron(s) orbiting it.</obo:IAO_0000115>
<obo:IAO_0000116>This atom is closely related to ChEBI's atom, but not exactly equivalent to.</obo:IAO_0000116>
<rdfs:label xml:lang="en">atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000007"/>
<obo:IAO_0000116>Some people may be uncomfortable calling every proton an atomic nucleus</obo:IAO_0000116>
<obo:IAO_0000116>This is equivalent to CHEBI:33252</obo:IAO_0000116>
<rdfs:label xml:lang="en">atomic nucleus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000011"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000080"/>
<obo:IAO_0000115>A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom.</obo:IAO_0000115>
<obo:IAO_0000116>This molecular entity is different than ChEBI's 'molecular entity'.</obo:IAO_0000116>
<obo:IAO_0000116>We would like to have cardinality restrictions on the logic, but there are some technical limitations.</obo:IAO_0000116>
<rdfs:label xml:lang="en">molecular entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000014">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<obo:IAO_0000115>A material entity consisting of multiple atoms that are completely connected by covalent bonds and structured in subunits, and where the most determinate class identity of the macromolecule is not necessarily changed when there is an addition or subtraction of atoms or bonds.</obo:IAO_0000115>
<obo:IAO_0000116>Terms moved to 'molecular entity', see https://github.com/OBOFoundry/Experimental-OBO-Core/issues/33</obo:IAO_0000116>
<rdfs:label xml:lang="en">obsolete macromolecular entity</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000013"/>
<rdfs:label xml:lang="en">protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<obo:IAO_0000115>A material entity that has a plasma membrane and results from cellular division.</obo:IAO_0000115>
<obo:IAO_0000116>CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc.</obo:IAO_0000116>
<obo:IAO_0000116>We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism.</obo:IAO_0000116>
<rdfs:label xml:lang="en">cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000017"/>
<rdfs:label xml:lang="en">native cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000017"/>
<rdfs:label xml:lang="en">cell in vitro</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000013"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>A material entity consisting of at least two macromolecular entities derived from a cell as parts, and that has a function for the cell.</obo:IAO_0000115>
<obo:IAO_0000116>Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes.</obo:IAO_0000116>
<obo:IAO_0000116>Overlaps with some cellular components from GO</obo:IAO_0000116>
<rdfs:label xml:lang="en">subcellular structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<obo:IAO_0000115>A part of a multicellular organism that is a collection of cell components that are not all contained in one cell.</obo:IAO_0000115>
<obo:IAO_0000116>Bodily fluids, such as urine, are currently defined as anatomical entities in UBERON. We should make sure there is a proper home for these here.</obo:IAO_0000116>
<rdfs:label xml:lang="en">gross anatomical part</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<obo:IAO_0000115>A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome.</obo:IAO_0000115>
<obo:IAO_0000116>"Maximal functionally integrated unit" is intended to express unity, which Barry considers synonymous with BFO 'object'.</obo:IAO_0000116>
<obo:IAO_0000116>Includes virus - we will later have a class for cellular organisms.</obo:IAO_0000116>
<rdfs:label xml:lang="en">organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<obo:IAO_0000116>Should revisit if we can place outside of material entity - a collection of roles.</obo:IAO_0000116>
<rdfs:label xml:lang="en">organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is created or changed during material processing.</obo:IAO_0000115>
<rdfs:label xml:lang="en">processed material entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000031">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label xml:lang="en">immaterial entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000031"/>
<rdfs:label xml:lang="en">geographical location</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000502"/>
<rdfs:label xml:lang="en">realizable</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000034">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000072"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000082"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000113"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000083"/>
<rdfs:label xml:lang="en">completely executed planned process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<rdfs:subClassOf>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000070"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000022"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000070"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000072"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000022"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000071"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000022"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000038"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000038"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000065"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000066"/>
<obo:IAO_0000115>A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective.</obo:IAO_0000115>
<obo:IAO_0000116>A biological process is an evolved process</obo:IAO_0000116>
<rdfs:label xml:lang="en">biological process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000074"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/COB_0000073"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/COB_0000075"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000065"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000066"/>
<obo:IAO_0000116>This is the same as GO molecular function</obo:IAO_0000116>
<rdfs:label xml:lang="en">gene product or complex activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000011"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000043"/>
<rdfs:label>monoatomic ion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000011"/>
<rdfs:label>uncharged atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000013"/>
<rdfs:label>nucleic acid polymer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:label>collection of organisms</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000031"/>
<rdfs:label>immaterial anatomical entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000031"/>
<rdfs:label>site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000058 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000058">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000061"/>
<rdfs:label>conclusion based on data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000061">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000002"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000120"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000513"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000116>Pier: 'data, information or knowledge'. OR 'representation</obo:IAO_0000116>
<rdfs:label>information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000062 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000062">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000061"/>
<rdfs:label>disease diagnosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000061"/>
<rdfs:label>phenotypic finding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<rdfs:label>disease course</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000065 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000065">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/COB_0000066"/>
<rdfs:label>environmental process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000034"/>
<obo:IAO_0000116>This is meant to capture processes that are more fundamental than macromolecular activities</obo:IAO_0000116>
<rdfs:label>physico-chemical process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:label>ecosystem</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000068 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000068">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000006"/>
<rdfs:label>geophysical entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000069">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000061"/>
<rdfs:label>directive information entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000013"/>
<rdfs:label>gene product</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000075">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000080"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000073"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000116>This is not covalently bonded, which conflicts with changes to the parent definition.</obo:IAO_0000116>
<rdfs:label>protein-containing macromolecular complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000069"/>
<rdfs:label>objective specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000069"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000076"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/COB_0000047"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000077"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label>action specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/COB_0000069"/>
<rdfs:subClassOf>
<owl:Restriction>