diff --git a/src/realizations/catchment/CMakeLists.txt b/src/realizations/catchment/CMakeLists.txt
index caec64b03d..11efabdb83 100644
--- a/src/realizations/catchment/CMakeLists.txt
+++ b/src/realizations/catchment/CMakeLists.txt
@@ -29,7 +29,6 @@ target_link_libraries(realizations_catchment PUBLIC
         )
 
 if(NGEN_ACTIVATE_PYTHON)
-   target_include_directories(realizations_catchment PUBLIC ${PROJECT_SOURCE_DIR}/extern/pybind11/include)
    target_link_libraries(realizations_catchment PUBLIC pybind11::embed)
    configure_file(Bmi_Py_Build_Versions.in Bmi_Py_Build_Versions.cpp)
    target_sources(realizations_catchment PRIVATE Bmi_Py_Build_Versions.cpp)