diff --git a/packages/calcite-components/src/components/label/label.tsx b/packages/calcite-components/src/components/label/label.tsx
index bd24c6ddade..06f9d89d9c6 100644
--- a/packages/calcite-components/src/components/label/label.tsx
+++ b/packages/calcite-components/src/components/label/label.tsx
@@ -1,5 +1,19 @@
-import { Component, Element, Event, EventEmitter, h, Host, Prop, VNode } from "@stencil/core";
-import { labelConnectedEvent, labelDisconnectedEvent } from "../../utils/label";
+import {
+  Component,
+  Element,
+  Event,
+  EventEmitter,
+  h,
+  Host,
+  Prop,
+  VNode,
+  Watch,
+} from "@stencil/core";
+import {
+  associateExplicitLabelToUnlabeledComponent,
+  labelConnectedEvent,
+  labelDisconnectedEvent,
+} from "../../utils/label";
 import { Alignment, Scale } from "../interfaces";
 import { CSS } from "./resources";
 
@@ -24,6 +38,11 @@ export class Label {
   /** Specifies the `id` of the component the label is bound to. Use when the component the label is bound to does not reside within the component. */
   @Prop({ reflect: true }) for: string;
 
+  @Watch("for")
+  handleForChange(): void {
+    associateExplicitLabelToUnlabeledComponent(this.el);
+  }
+
   /** Specifies the size of the component. */
   @Prop({ reflect: true }) scale: Scale = "m";
 
diff --git a/packages/calcite-components/src/tests/commonTests.ts b/packages/calcite-components/src/tests/commonTests.ts
index e208679342f..b70c0a50b0f 100644
--- a/packages/calcite-components/src/tests/commonTests.ts
+++ b/packages/calcite-components/src/tests/commonTests.ts
@@ -646,6 +646,30 @@ export function labelable(
         shadowFocusTargetSelector,
       });
     });
+
+    it("is labelable when label's for is set after initialization", async () => {
+      const siblingHtml = html`
+        <calcite-label>${labelTitle}</calcite-label>
+        ${componentHtml}
+      `;
+      const siblingPage: E2EPage = await newE2EPage();
+      beforeContent?.(siblingPage);
+
+      await siblingPage.setContent(siblingHtml);
+      await siblingPage.waitForChanges();
+
+      const label = await siblingPage.find("calcite-label");
+      label.setProperty("for", id);
+      await siblingPage.waitForChanges();
+
+      await assertLabelable({
+        page: siblingPage,
+        componentTag,
+        propertyToToggle,
+        focusTargetSelector,
+        shadowFocusTargetSelector,
+      });
+    });
   });
 }
 
diff --git a/packages/calcite-components/src/utils/component.spec.ts b/packages/calcite-components/src/utils/component.spec.ts
index 82cb4369348..ca7fa99d1bf 100644
--- a/packages/calcite-components/src/utils/component.spec.ts
+++ b/packages/calcite-components/src/utils/component.spec.ts
@@ -1,4 +1,6 @@
-import { getIconScale } from "./component";
+import { componentOnReady, getIconScale } from "./component";
+import { html } from "../../support/formatting";
+import { HTMLStencilElement } from "@stencil/core/internal";
 
 describe("getIconScale", () => {
   it('should return "m" when input is "l"', () => {
@@ -10,3 +12,40 @@ describe("getIconScale", () => {
     expect(getIconScale("s")).toBe("s");
   });
 });
+
+describe("componentOnReady", () => {
+  let requestAnimationFrameSpy: jest.SpyInstance;
+  let fakeComponent: HTMLElement;
+
+  beforeEach(() => {
+    document.body.innerHTML = html` <fake-component></fake-component> `;
+    fakeComponent = document.querySelector<HTMLElement>("fake-component");
+
+    const originalRaf = globalThis.requestAnimationFrame;
+    requestAnimationFrameSpy = jest
+      .spyOn(globalThis, "requestAnimationFrame")
+      .mockImplementation((callback) => originalRaf(callback));
+  });
+
+  afterEach(() => requestAnimationFrameSpy.mockRestore());
+
+  it("should call componentOnReady if it exists on the element (lazy-loaded)", async () => {
+    const componentOnReadyStub = ((fakeComponent as HTMLStencilElement).componentOnReady = jest.fn());
+
+    const promise = componentOnReady(fakeComponent);
+    expect(promise).toBeInstanceOf(Promise);
+
+    await promise;
+    expect(componentOnReadyStub).toHaveBeenCalled();
+  });
+
+  it("waits for an animation frame if componentOnReady does not exist on the element", async () => {
+    expect(requestAnimationFrameSpy).not.toHaveBeenCalled();
+
+    const promise = componentOnReady(fakeComponent);
+    expect(promise).toBeInstanceOf(Promise);
+
+    await promise;
+    expect(requestAnimationFrameSpy).toHaveBeenCalled();
+  });
+});
diff --git a/packages/calcite-components/src/utils/component.ts b/packages/calcite-components/src/utils/component.ts
index c8477fee4cc..645f3552131 100644
--- a/packages/calcite-components/src/utils/component.ts
+++ b/packages/calcite-components/src/utils/component.ts
@@ -1,5 +1,23 @@
 import { Scale } from "../components/interfaces";
+import { HTMLStencilElement } from "@stencil/core/internal";
 
 export function getIconScale(componentScale: Scale): Extract<Scale, "s" | "m"> {
   return componentScale === "l" ? "m" : "s";
 }
+
+/**
+ * This util helps us wait for a component to be ready for both lazy-loading (`dist` output) and non-lazy-loading (`components` output) components.
+ *
+ * Based on https://github.com/ionic-team/ionic-framework/blob/1a8bd6d/core/src/utils/helpers.ts#L60C1-L79C3
+ *
+ * @param el - the host element to wait for
+ */
+export async function componentOnReady(el: HTMLElement): Promise<void> {
+  await (isStencilEl(el)
+    ? el.componentOnReady()
+    : new Promise<void>((resolve) => requestAnimationFrame(() => resolve())));
+}
+
+function isStencilEl(el: HTMLElement): el is HTMLStencilElement {
+  return typeof (el as HTMLStencilElement).componentOnReady === "function";
+}
diff --git a/packages/calcite-components/src/utils/label.ts b/packages/calcite-components/src/utils/label.ts
index aeb3dd6968f..00c0a6f4f31 100644
--- a/packages/calcite-components/src/utils/label.ts
+++ b/packages/calcite-components/src/utils/label.ts
@@ -1,4 +1,5 @@
 import { closestElementCrossShadowBoundary, isBefore, queryElementRoots } from "./dom";
+import { componentOnReady } from "./component";
 
 export interface LabelableComponent {
   /**
@@ -41,7 +42,7 @@ const labelToLabelables = new WeakMap<HTMLCalciteLabelElement, LabelableComponen
 const onLabelClickMap = new WeakMap<HTMLCalciteLabelElement, typeof onLabelClick>();
 const onLabelConnectedMap = new WeakMap<LabelableComponent, typeof onLabelConnected>();
 const onLabelDisconnectedMap = new WeakMap<LabelableComponent, typeof onLabelDisconnected>();
-const unlabeledComponents = new WeakSet<LabelableComponent>();
+const unlabeledComponents = new Set<LabelableComponent>();
 
 const findLabelForComponent = (componentEl: HTMLElement): HTMLCalciteLabelElement | null => {
   const { id } = componentEl;
@@ -70,7 +71,7 @@ function hasAncestorCustomElements(label: HTMLCalciteLabelElement, componentEl:
   let traversedElements: HTMLElement[];
   const customElementAncestorCheckEventType = "custom-element-ancestor-check";
 
-  const listener = (event) => {
+  const listener = (event: CustomEvent) => {
     event.stopImmediatePropagation();
     const composedPath = event.composedPath() as HTMLElement[];
     traversedElements = composedPath.slice(composedPath.indexOf(componentEl), composedPath.indexOf(label));
@@ -94,6 +95,10 @@ function hasAncestorCustomElements(label: HTMLCalciteLabelElement, componentEl:
  * @param component
  */
 export function connectLabel(component: LabelableComponent): void {
+  if (!component) {
+    return;
+  }
+
   const labelEl = findLabelForComponent(component.el);
 
   if (
@@ -132,6 +137,10 @@ export function connectLabel(component: LabelableComponent): void {
  * @param component
  */
 export function disconnectLabel(component: LabelableComponent): void {
+  if (!component) {
+    return;
+  }
+
   unlabeledComponents.delete(component);
   document.removeEventListener(labelConnectedEvent, onLabelConnectedMap.get(component));
   document.removeEventListener(labelDisconnectedEvent, onLabelDisconnectedMap.get(component));
@@ -202,3 +211,33 @@ function onLabelDisconnected(this: LabelableComponent): void {
   onLabelConnectedMap.set(this, boundOnLabelConnected);
   document.addEventListener(labelConnectedEvent, boundOnLabelConnected);
 }
+
+/**
+ * Helper to associate an explicit label (i.e., using `for`) with a labelable component that does not have an associated label.
+ *
+ * @param label - the label element
+ */
+export async function associateExplicitLabelToUnlabeledComponent(label: HTMLCalciteLabelElement): Promise<void> {
+  await componentOnReady(label);
+
+  const alreadyLabeled = labelToLabelables.has(label);
+
+  if (alreadyLabeled) {
+    return;
+  }
+
+  const forComponentEl = label.ownerDocument?.getElementById(label.for);
+
+  if (!forComponentEl) {
+    return;
+  }
+
+  requestAnimationFrame(() => {
+    for (const labelable of unlabeledComponents) {
+      if (labelable.el === forComponentEl) {
+        connectLabel(labelable);
+        break;
+      }
+    }
+  });
+}