diff --git a/build.rs b/build.rs
index be75387af6be..231b1266261b 100644
--- a/build.rs
+++ b/build.rs
@@ -28,9 +28,15 @@ fn is_docs_rs() -> bool {
 }
 
 fn is_sidecar_ffi_enabled() -> bool {
-    // Opt-out building the F3 sidecar staticlib
-    match std::env::var("FOREST_F3_SIDECAR_FFI_BUILD_OPT_OUT") {
-        Ok(value) => !matches!(value.to_lowercase().as_str(), "1" | "true"),
-        _ => true,
+    // Note: arm64 is disabled for now as cross-compilation is not yet supported in rust2go
+    // and it's reported rust2go build does not work on arm64 MacOS
+    if cfg!(target_arch = "x86_64") {
+        // Opt-out building the F3 sidecar staticlib
+        match std::env::var("FOREST_F3_SIDECAR_FFI_BUILD_OPT_OUT") {
+            Ok(value) => !matches!(value.to_lowercase().as_str(), "1" | "true"),
+            _ => true,
+        }
+    } else {
+        false
     }
 }