get_gene.py

#!/usr/bin/env python3
# -*- coding: utf-8 -*-

"""
Fetch scores across all screens for a single gene
using customizable filtering options
"""

import requests
from core import config as cfg

gene_id = 7023
request_url = cfg.BASE_URL + "/gene/" + str(gene_id)

# These parameters can be modified to match any search criteria following
# the rules outlined in the Wiki: https://wiki.thebiogrid.org/doku.php/orcs:webservice
# In this particular instance, we've chosen to limit results to only those in which
# our gene of interest is considered a hit
params = {
    "accesskey": cfg.ACCESS_KEY,
    "format": "json",
    "hit": "yes"
}

r = requests.get( request_url, params = params )
scores = r.json( )

data = {}
for row in scores :
    # Create a hash of results by gene identifier
    data[row['SCREEN_ID']] = row

# Print out data about the gene from several specific screens
print( data['549'] )
print( data['170'] )
print( data['197'] )

""" 
Output as of version 1.0.1:
{'SCORE.2': '0.0108', 'ORGANISM_OFFICIAL': 'Homo sapiens', 'IDENTIFIER_TYPE': 'gene', 'OFFICIAL_SYMBOL': 'TFAP4', 'SCORE.3': '-', 'SCREEN_ID': '549', 'HIT': 'YES', 'IDENTIFIER_ID': '7023', 'SCORE.1': '-0.6694077', 'SOURCE': 'BioGRID ORCS', 'ALIASES': 'AP-4|bHLHc41', 'ORGANISM_ID': '9606', 'SCORE.4': '-', 'SCORE.5': '-'}
{'SCORE.2': '0.831183816', 'ORGANISM_OFFICIAL': 'Homo sapiens', 'IDENTIFIER_TYPE': 'gene', 'OFFICIAL_SYMBOL': 'TFAP4', 'SCORE.3': '0.963569948', 'SCREEN_ID': '170', 'HIT': 'YES', 'IDENTIFIER_ID': '7023', 'SCORE.1': '1.384515796', 'SOURCE': 'BioGRID ORCS', 'ALIASES': 'AP-4|bHLHc41', 'ORGANISM_ID': '9606', 'SCORE.4': '0.960101193', 'SCORE.5': '-'}
{'SCORE.2': '0.00408', 'ORGANISM_OFFICIAL': 'Homo sapiens', 'IDENTIFIER_TYPE': 'gene', 'OFFICIAL_SYMBOL': 'TFAP4', 'SCORE.3': '-', 'SCREEN_ID': '197', 'HIT': 'YES', 'IDENTIFIER_ID': '7023', 'SCORE.1': '-0.595238539', 'SOURCE': 'BioGRID ORCS', 'ALIASES': 'AP-4|bHLHc41', 'ORGANISM_ID': '9606', 'SCORE.4': '-', 'SCORE.5': '-'}
"""