diff --git a/samples/package_management/bioc_setup.sh b/samples/package_management/bioc_setup.sh
index 1cfc377b..aa865a42 100755
--- a/samples/package_management/bioc_setup.sh
+++ b/samples/package_management/bioc_setup.sh
@@ -1,3 +1,5 @@
+yum erase microsoft-r-open-mro-3.3* --assumeyes
+
 if [ ! -d "microsoft-r-open" ]; then
     # Download R
     wget https://mran.microsoft.com/install/mro/3.4.0/microsoft-r-open-3.4.0.tar.gz